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https://www.readbyqxmd.com/read/28545058/a-systematic-genomic-screen-implicates-nucleocytoplasmic-transport-and-membrane-growth-in-nuclear-size-control
#1
Kazunori Kume, Helena Cantwell, Frank R Neumann, Andrew W Jones, Ambrosius P Snijders, Paul Nurse
How cells control the overall size and growth of membrane-bound organelles is an important unanswered question of cell biology. Fission yeast cells maintain a nuclear size proportional to cellular size, resulting in a constant ratio between nuclear and cellular volumes (N/C ratio). We have conducted a genome-wide visual screen of a fission yeast gene deletion collection for viable mutants altered in their N/C ratio, and have found that defects in both nucleocytoplasmic mRNA transport and lipid synthesis alter the N/C ratio...
May 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28544336/regulation-of-controlled-substance-prescribing-an-overview-for-certified-nurse-midwives-and-certified-midwives
#2
Kathryn Osborne
In addition to the regulation of prescriptive authority and prescribing practices conducted by individual states, the prescription of controlled substances is also regulated at the federal level by the US Drug Enforcement Administration (DEA). While there are variations in state laws relative to controlled substance prescribing, federal law is uniform across states as established by the Controlled Substances Act (21 United States Code § 801-890) and the DEA Regulations (Title 21, Code of Federal Regulations)...
May 23, 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28535773/nurses-who-work-in-rural-and-remote-communities-in-canada-a-national-survey
#3
Martha L P MacLeod, Norma J Stewart, Judith C Kulig, Penny Anguish, Mary Ellen Andrews, Davina Banner, Leana Garraway, Neil Hanlon, Chandima Karunanayake, Kelley Kilpatrick, Irene Koren, Julie Kosteniuk, Ruth Martin-Misener, Nadine Mix, Pertice Moffitt, Janna Olynick, Kelly Penz, Larine Sluggett, Linda Van Pelt, Erin Wilson, Lela Zimmer
BACKGROUND: In Canada, as in other parts of the world, there is geographic maldistribution of the nursing workforce, and insufficient attention is paid to the strengths and needs of those providing care in rural and remote settings. In order to inform workforce planning, a national study, Nursing Practice in Rural and Remote Canada II, was conducted with the rural and remote regulated nursing workforce (registered nurses, nurse practitioners, licensed or registered practical nurses, and registered psychiatric nurses) with the intent of informing policy and planning about improving nursing services and access to care...
May 23, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/28532509/barriers-and-facilitators-to-healthcare-professional-behaviour-change-in-clinical-trials-using-the-theoretical-domains-framework-a-case-study-of-a-trial-of-individualized-temperature-reduced-haemodialysis
#4
Justin Presseau, Brittany Mutsaers, Ahmed A Al-Jaishi, Janet Squires, Christopher W McIntyre, Amit X Garg, Manish M Sood, Jeremy M Grimshaw
BACKGROUND: Implementing the treatment arm of a clinical trial often requires changes to healthcare practices. Barriers to such changes may undermine the delivery of the treatment making it more likely that the trial will demonstrate no treatment effect. The 'Major outcomes with personalized dialysate temperature' (MyTEMP) is a cluster-randomised trial to be conducted in 84 haemodialysis centres across Ontario, Canada to investigate whether there is a difference in major outcomes with an individualized dialysis temperature (IDT) of 0...
May 22, 2017: Trials
https://www.readbyqxmd.com/read/28522430/the-drosophila-lin54-homolog-mip120-controls-two-aspects-of-oogenesis
#5
Mei-Hsin Cheng, Laura Andrejka, Paul J Vorster, Albert Hinman, Joseph S Lipsick
The conserved multi-protein MuvB core associates with the Myb oncoproteins and with the RB-E2F-DP tumor suppressor proteins in complexes that regulate cell proliferation, differentiation, and apoptosis. Drosophila Mip120, a homolog of LIN54, is a sequence-specific DNA-binding protein within the MuvB core. A mutant of Drosophila mip120 was previously shown to cause female and male sterility. We now show that Mip120 regulates two different aspects of oogenesis. First, in the absence of the Mip120 protein, egg chambers arrest during the transition from stage 7 to 8 with a failure of the normal program of chromosomal dynamics in the ovarian nurse cells...
May 18, 2017: Biology Open
https://www.readbyqxmd.com/read/28512345/phosphoproteome-analysis-reveals-phosphorylation-underpinnings-in-the-brains-of-nurse-and-forager-honeybees-apis-mellifera
#6
Gebreamlak Bezabih, Han Cheng, Bin Han, Mao Feng, Yu Xue, Han Hu, Jianke Li
The honeybee brain is a central organ in regulating wide ranges of honeybee biology, including life transition from nurse to forager bees. Knowledge is still lacking on how protein phosphorylation governs the neural activity to drive the age-specific labor division. The cerebral phosphoproteome of nurse and forager honeybees was characterized using Ti(4+)-IMAC phosphopeptide enrichment mass-spectrometry-based proteomics and protein kinases (PKs) were predicted. There were 3,077 phosphosites residing on 3,234 phosphopeptides from 1004 phosphoproteins in the nurse bees...
May 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28511309/-effect-of-occupational-exposure-on-job-burnout-in-nurses
#7
L G Zhang, T T Jin, Y Y Zhou, J D Yu, F Y Yu
Objective: To investigate the effect of occupational exposure on job burnout in nurses, and to analyze the mediating effect of negative emotion between occupational exposure and job burnout and the regulatory effect of supervisor support on occupational exposure and negative emotion. Methods: From September to December, 2015, simple random sampling was used to select 543 nurses from six tertiary hospitals in Zhejiang Province, China. The questionnaires consisted of occupational exposure risk questionnaire, negative emotion questionnaire, supervisor support questionnaire, and job burnout questionnaire...
March 20, 2017: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28509657/the-palliative-care-challenge-analysis-of-barriers-and-opportunities-to-integrate-palliative-care-in-europe-in-the-view-of-national-associations
#8
Carlos Centeno, Eduardo Garralda, José Miguel Carrasco, Marlieke den Herder-van der Eerden, Melissa Aldridge, David Stevenson, Diane E Meier, Jeroen Hasselaar
BACKGROUND: Palliative care (PC) development is diverse and lacks an effective integration into European healthcare systems. This article investigates levels of integrated PC in European countries. METHODS: A qualitative survey was undertaken for the 2013 EAPC Atlas of PC in Europe with boards of national associations, eliciting opinions on opportunities for, and barriers to, PC development. ANALYSIS: Barriers and opportunities directly related to PC integration were identified and analyzed thematically according (1) to the dimensions of the World Health Organization (WHO) public health model and (2) by the degree of service provision in each country...
May 16, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28494105/empathy-in-pediatric-intensive-care-nurses-part-2-neural-correlates
#9
Philip L Jackson, Margot Latimer, Fanny Eugène, Emily Macleod, Tara Hatfield, Etienne Vachon-Presseau, Pierre-Emmanuel Michon, Kenneth M Prkachin
AIMS: To determine if there are brain activity differences between pediatric intensive care nurses and allied health professionals during pain intensity rating tasks and test whether these differences are related to the population observed (infant or adult) and professional experience. BACKGROUND: The underestimation of patients' pain by healthcare professionals has generally been associated with patterns of change in neural response to vicarious pain, notably reduced activation in regions associated with affective sharing and increased activation in regions associated with regulation, compared with controls...
May 11, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28478877/microvascular-fluid-resuscitation-in-circulatory-shock
#10
REVIEW
Shannan K Hamlin, Penelope Z Strauss, Hsin-Mei Chen, LaDonna Christy
The microcirculation is responsible for blood flow regulation and red blood cell distribution throughout individual organs. Patients with circulatory shock have acute failure of the cardiovascular system in which there is insufficient delivery of oxygen to meet metabolic tissue requirements. All subtypes of shock pathophysiology have a hypovolemic component. Fluid resuscitation guided by systemic hemodynamic end points is a common intervention. Evidence shows that microcirculatory shock persists even after optimization of macrocirculatory hemodynamics...
June 2017: Nursing Clinics of North America
https://www.readbyqxmd.com/read/28476936/genome-wide-screen-for-cell-growth-regulators-in-fission-yeast
#11
Louise Weston, Jessica Greenwood, Paul Nurse
Cellular growth control is important for all living organisms but experimental investigation into this problem is difficult because of the complex range of growth regulatory mechanisms. We have used the fission yeast Schizosaccharomyces pombe to identify potential master regulators of growth. The S. pombe pat1(ts)mei4Δ strain enters the meiotic developmental program at restrictive temperature, but arrests in meiotic G2 phase as mei4(+) is essential for meiotic progression. These cells do not grow, even in an abundance of nutrients...
May 5, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28476255/-care-and-restraint-when-the-law-questions-nursing-practice
#12
Jean-Charles Scotti
With the reforms of 2011 and 2013 relating to psychiatric hospitalisation, raises the question of the suitability of modern psychiatric practice with regard to a person's recognised principles and basic rights. Achieving a balance is difficult and the Constitutional Council has joined the debate, bringing to an end any idea of compromise between safety and freedom. A decision which was made as a result of a clarification of certain regulations which have proved controversial from the point of view of individual liberties...
May 2017: Soins. Psychiatrie
https://www.readbyqxmd.com/read/28468702/bridging-the-policy-clinical-practice-divide-a-conversation-with-parmeeth-m-s-atwal-jd-msn-rn-mph-fnp
#13
Marie Manthey
Marie Manthey, founder of Creative Health Care Management, interviews Parmeeth "Par" Atwal, whose first career included representing the National Association of Community Health Centers as an attorney, editor of a major health policy journal, and a senior position in the Office of the National Coordinator for Health Information Technology at the U.S. Department of Health and Human Services. He then became an active participant in the health care system, earning a bachelor of science in nursing, working in cardiac critical care, and now becoming a family nurse practitioner...
May 1, 2017: Creative Nursing
https://www.readbyqxmd.com/read/28467286/uncovering-common-sleep-disorders-and-their-impacts-on-occupational-performance
#14
Sylvia R Judd
Sleep is an active process; the body undergoes restoration and regeneration. Adequate sleep is essential to health and cognitive function. Sleep is critical for cell repair, a healthy immune system, and hormonal regulation, and aids in the process of learning, memory, and emotion. Inadequate sleep can lead to multiple chronic health and mental conditions over time. The occupational health nurse can be instrumental in screening for two of the most common sleep disorders, insomnia and obstructive sleep apnea, by asking workers key questions and using simple screening tools...
May 2017: Workplace Health & Safety
https://www.readbyqxmd.com/read/28460722/-the-regulation-of-nursing-record-keeping
#15
Grégory Caumes
Record-keeping guarantees a permanent trace of a patient's treatment and the legal protection of the nurse. Legislation provides a regulatory framework. It is also a matter of professionalisation and improvement of practices.
May 2017: Revue de L'infirmière
https://www.readbyqxmd.com/read/28458751/patient-tracking-in-earthquake-emergency-response-in-iran-a-qualitative-study
#16
Nahid Tavakoli, Mohammad H Yarmohammadian, Reza Safdari, Mahmoud Keyvanara
BACKGROUND: After a disaster, all victims have to be rapidly and accurately identified for locating, tracking and regulating them. The purpose of this study was to summarize people's experiences that how the patients were tracked in past earthquake disasters in Iran. METHODS: A qualitative study was carried out in 2015. This was an interview-based qualitative study using content analysis. The interviewed people included physicians, nurses, emergency medical technicians, disaster managers, Red Crescent Society' first responders and managers...
2017: World Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28457775/experiences-of-rural-and-remote-nurses-assisting-with-disasters
#17
Judith C Kulig, Kelly Penz, Chandima Karunanayake, Martha L P MacLeod, Sharleen Jahner, Mary Ellen Andrews
BACKGROUND: Globally, disasters are on the rise. Nurses play a significant role in responding to such events but little is known about rural and remote nurses' experiences. METHODS: A national cross-sectional survey of regulated nurses (registered nurses, registered psychiatric nurses, licensed practical nurses and nurse practitioners) in rural and remote Canada provided the data (n=2465) for the logistic regression of predictors of assisting with a disaster event within the last five years...
April 27, 2017: Australasian Emergency Nursing Journal: AENJ
https://www.readbyqxmd.com/read/28451529/efficacy-of-emotion-regulation-for-patients-suffering-from-chronic-obstructive-pulmonary-disease
#18
Hongling Wang, Zhenhua Wei, Xue Li, Yongjie Li
BACKGROUND: To study the influence values of self-management program intervention on efficacy of emotion regulation for patients suffering from chronic obstructive pulmonary disease (COPD). METHODS: Eighty-six diagnosed chronic COPD patients in stable phase in Linzi District People's Hospital, Zibo Shandong Province, PR China from June 2014 to June 2015 were selected in succession. They were divided into control group and observation group randomly with 43 cases in each group...
January 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28446103/preceptorships-planned-for-all-new-nurses-and-midwives
#19
Matthew Mckew
All new nurses should complete a mandatory preceptorship year, an academic heading up the regulator's 'radical' overhaul of education standards has said.
April 27, 2017: Nursing Management (Harrow)
https://www.readbyqxmd.com/read/28422621/historic-leadership-one-courageous-school-nurse-s-heroic-journey-part-3
#20
Ellen F Johnsen, Katherine J Pohlman
School nursing practice establishes itself in the midst of both education and nursing philosophies, ethics, standards, laws, and regulations. Treading these two worlds is difficult at times and requires that a school nurse possess a strong foundational knowledge base, seek professional collaboration, and navigate conflicting professional demands in order to promote student and public safety. This article is Part 3 of a four-part series that recounts the inspiring story of a school nurse, Ellen Johnsen, who did just that back in the 1980s in Broken Arrow, Oklahoma...
May 2017: NASN School Nurse
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