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https://www.readbyqxmd.com/read/28820677/comparing-measures-of-general-and-abdominal-adiposity-as-predictors-of-blood-pressure-in-college-students
#1
Demetrius A Abshire, Gia Mudd-Martin, Debra K Moser, Terry A Lennie
OBJECTIVE: To compare anthropometric measures of body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), and sagittal abdominal diameter (SAD) as predictors of blood pressure in college students. PARTICIPANTS: Students (N = 116) were recruited from November 2012 through May 2014 at an urban university and rural community colleges. METHODS: Students underwent a brief physical examination during which anthropometric measures were obtained and blood pressure was measured...
August 18, 2017: Journal of American College Health: J of ACH
https://www.readbyqxmd.com/read/28819305/cardiorespiratory-pathogenesis-of-sickle-cell-disease-in-a-mouse-model
#2
Jun Ren, Xiuqing Ding, Marie Trudel, John J Greer, Joanna E MacLean
The nature and development of cardiorespiratory impairments associated with sickle cell disease are poorly understood. Given that the mechanisms of these impairments cannot be addressed adequately in clinical studies, we characterized cardiorespiratory pathophysiology from birth to maturity in the sickle cell disease SAD mouse model. We identified two critical phases of respiratory dysfunction in SAD mice; the first prior to weaning and the second in adulthood. At postnatal day 3, 43% of SAD mice showed marked apneas, anemia, and pulmonary vascular congestion typical of acute chest syndrome; none of these mice survived to maturity...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28816911/resilience-in-adolescents-with-cancer-association-of-coping-with-positive-and-negative-affect
#3
Lexa K Murphy, Alexandra H Bettis, Meredith A Gruhn, Cynthia A Gerhardt, Kathryn Vannatta, Bruce E Compas
OBJECTIVE: To examine the prospective association between adolescents' coping with cancer-related stress and observed positive and negative affect during a mother-adolescent interaction task involving discussion of cancer-related stressors. METHODS: Adolescents (age 10-15 years) self-reported about their coping and affect approximately 2 months after cancer diagnosis. Approximately 3 months later, adolescents and mothers were video recorded having a discussion about cancer, and adolescents were coded for expression of positive affect (positive mood) and negative affect (sadness and anxiety)...
August 9, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28815940/production-and-perception-of-emotional-prosody-by-adults-with-autism-spectrum-disorder
#4
Daniel J Hubbard, Daniel J Faso, Peter F Assmann, Noah J Sasson
This study examined production and perception of affective prosody by adults with autism spectrum disorder (ASD). Previous research has reported increased pitch variability in talkers with ASD compared to typically developing (TD) controls in grammatical speaking tasks (e.g., comparing interrogative vs. declarative sentences), but it is unclear whether this pattern extends to emotional speech. In this study, speech recordings in five emotion contexts (angry, happy, interested, sad, and neutral) were obtained from 15 adult males with ASD and 15 controls (Experiment 1), and were later presented to 52 listeners (22 with ASD) who were asked to identify the emotion expressed and rate the level of naturalness of the emotion in each recording (Experiment 2)...
August 17, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28815639/safety-tolerability-and-pharmacokinetic-characteristics-of%C3%A2-a-novel-nonopioid-analgesic-vvz-149-injections-in-healthy-volunteers-a-first-in-class-first-in-human-study
#5
Jaeseong Oh, SeungHwan Lee, Anhye Kim, Jangsoo Yoon, Kyungho Jang, Doo H Lee, Sunyoung Cho, Sang Rim Lee, Kyung-Sang Yu, Jae-Yong Chung
VVZ-149, a dual antagonist of GlyT2 and 5HT2 A receptors, is an investigational analgesic with a novel mechanism of action that is currently under early-stage clinical development as an injectable agent for the treatment of postoperative pain. Here, the safety, tolerability, and pharmacokinetics of VVZ-149 injections in healthy male volunteers were explored in a randomized, double-blind, single- and multiple-ascending-dose (SAD and MAD, respectively), placebo-controlled clinical study. Subjects randomly received a 4-hour intravenous infusion of 0...
August 16, 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28814736/emotions-alter-muscle-proprioceptive-coding-of-movements-in-humans
#6
Rochelle Ackerley, Jean-Marc Aimonetti, Edith Ribot-Ciscar
Emotions can evoke strong reactions that have profound influences, from gross changes in our internal environment to small fluctuations in facial muscles, and reveal our feelings overtly. Muscles contain proprioceptive afferents, informing us about our movements and regulating motor activities. Their firing reflects changes in muscle length, yet their sensitivity can be modified by the fusimotor system, as found in animals. In humans, the sensitivity of muscle afferents is modulated by cognitive processes, such as attention; however, it is unknown if emotional processes can modulate muscle feedback...
August 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28813793/the-combined-action-of-a-passive-exoskeleton-and-an-emg-controlled-neuroprosthesis-for-upper-limb-stroke-rehabilitation-first-results-of-the-retrainer-project
#7
E Ambrosini, S Ferrante, J Zajc, M Bulgheroni, W Baccinelli, E d'Amico, T Schauer, C Wiesener, M Russold, M Gfoehler, M Puchinger, M Weber, S Becker, K Krakow, M Rossini, D Proserpio, G Gasperini, F Molteni, G Ferrigno, A Pedrocchi
The combined use of Functional Electrical Stimulation (FES) and robotic technologies is advocated to improve rehabilitation outcomes after stroke. This work describes an arm rehabilitation system developed within the European project RETRAINER. The system consists of a passive 4-degrees-of-freedom exoskeleton equipped with springs to provide gravity compensation and electromagnetic brakes to hold target positions. FES is integrated in the system to provide additional support to the most impaired muscles. FES is triggered based on the volitional EMG signal of the same stimulated muscle; in order to encourage the active involvement of the patient the volitional EMG is also monitored throughout the task execution and based on it a happy or sad emoji is visualized at the end of each task...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28812274/oxytocin-and-anxiety-disorders
#8
Michael G Gottschalk, Katharina Domschke
In the present chapter, we review the literature focusing on oxytocin (OT)-centered research in anxiety spectrum conditions, comprising separation anxiety disorder, specific phobias, social anxiety disorder (SAD), panic disorder, generalized anxiety disorder, and anxiety-related endophenotypes (e.g., trust behavior, behavioral inhibition, neuroticism, and state/trait anxiety). OT receptor gene (OXTR) polymorphisms have been implicated in gene-environment interactions with attachment style and childhood maltreatment and to influence clinical outcomes, including SAD intensity and limbic responsiveness...
August 16, 2017: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/28811112/exogenous-testosterone-affects-early-threat-processing-in-socially-anxious-and-healthy-women
#9
Jacobien M van Peer, Dorien Enter, Henk van Steenbergen, Philip Spinhoven, Karin Roelofs
Testosterone plays an important role in social threat processing. Recent evidence suggests that testosterone administration has socially anxiolytic effects, but it remains unknown whether this involves early vigilance or later, more sustained, processing-stages. We investigated the acute effects of testosterone administration on social threat processing in 19 female patients with Social Anxiety Disorder (SAD) and 19 healthy controls. Event-related potentials (ERPs) were recorded during an emotional Stroop task with subliminally presented faces...
August 12, 2017: Biological Psychology
https://www.readbyqxmd.com/read/28810437/a-systematic-review-of-the-association-between-emotions-and-eating-behaviour-in-normal-and-overweight-adult-populations
#10
Tracey J Devonport, Wendy Nicholls, Christopher Fullerton
A systematic review was completed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive search of four electronic databases (2004-2015) yielded 60,017 articles, of which 29 met inclusion criteria. Included studies performed poorly on data quality analysis in terms of randomisation and controlling for confounding factors. Participant's body mass index scores range from 19.73 (standard deviation = 1.54) to 28.4 (standard deviation = 1.4) kg/m(2)...
March 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28807703/is-early-palliative-care-feasible-in-patients-with-multiple-myeloma
#11
Josep Porta-Sales, Maria Guerrero-Torrelles, Deborah Moreno-Alonso, Josep Sarra-Escarre, Victòria Clapés-Puig, Jordi Trelis-Navarro, Anna Sureda-Balarí, Alberto Fernández De Sevilla-Ribosa
CONTEXT: Evidence for the benefits of early palliative care (EPC) in patients with solid tumors is strong, but EPC has received scant attention in hematological malignancies. OBJECTIVE: To assess the benefits of outpatient-based EPC for symptom control in patients with multiple myeloma. METHODS: Retrospective study of patients attending the Multiple Myeloma Palliative Care Clinic (MM-PAL) at our hospital in the year 2013 (February 1 - December 31)...
August 11, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28806742/dissociating-maternal-responses-to-sad-and-happy-facial-expressions-of-their-own-child-an-fmri-study
#12
Dorothea Kluczniok, Catherine Hindi Attar, Jenny Stein, Sina Poppinga, Thomas Fydrich, Charlotte Jaite, Viola Kappel, Romuald Brunner, Sabine C Herpertz, Katja Boedeker, Felix Bermpohl
BACKGROUND: Maternal sensitive behavior depends on recognizing one's own child's affective states. The present study investigated distinct and overlapping neural responses of mothers to sad and happy facial expressions of their own child (in comparison to facial expressions of an unfamiliar child). METHODS: We used functional MRI to measure dissociable and overlapping activation patterns in 27 healthy mothers in response to happy, neutral and sad facial expressions of their own school-aged child and a gender- and age-matched unfamiliar child...
2017: PloS One
https://www.readbyqxmd.com/read/28802727/brain-activation-during-processing-of-genuine-facial-emotion-in-depression-preliminary-findings
#13
REVIEW
Samantha J Groves, Toni L Pitcher, Tracy R Melzer, Jennifer Jordan, Janet D Carter, Gin S Malhi, Lucy C Johnston, Richard J Porter
OBJECTIVE: The current study aimed to examine the neural correlates of processing genuine compared with posed emotional expressions, in depressed and healthy subjects using a novel functional magnetic resonance imaging (fMRI) paradigm METHOD: During fMRI scanning, sixteen depressed patients and ten healthy controls performed an Emotion Categorisation Task, whereby participants were asked to distinguish between genuine and non-genuine (posed or neutral) facial displays of happiness and sadness...
July 27, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28802301/sleep-duration-s-association-with-diet-physical-activity-mental-status-and-weight-among-korean-high-school-students
#14
Jounghee Lee
BACKGROUND AND OBJECTIVES: Sleep deprivation is a critical public health problem, especially in Korean adolescents. This study aimed to identify the association between sleep duration and dietary behaviors, physical activity, mental status, and nutritional status among high school students in South Korea. METHODS AND STUDY DESIGN: Based on the data collected from the 2014 Korea Youth Risk Behavior Web-based Survey, 31,407 high school students who met the inclusion criteria were selected and the association between sleep duration and selected health risk factors was identified using multivariable logistic regression models...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28800789/indicators-of-poorly-controlled-asthma-and-health-related-quality-of-life-among-school-age-children-in-the-united-states
#15
(no author information available yet)
BACKGROUND: Poorly controlled asthma has far-reaching effects on school-age children and their parents, but little is knownabout the national impact on health-related quality of life (HRQoL). OBJECTIVE: To examine HRQoL associated with asthma and indicators of poorly controlled asthma in the United States. METHODS: This was a cross-sectional analysis of HRQoL among school-age children (age range, 6-17 years) with asthma in the nationally representative 2007-2013 Medical Expenditure Panel Survey (MEPS)...
August 11, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28799677/text-message-reminders-for-improving-patient-appointment-adherence-in-an-office-based-buprenorphine-program-a-feasibility-study
#16
Babak Tofighi, Frank Grazioli, Sewit Bereket, Ellie Grossman, Yindalon Aphinyanaphongs, Joshua David Lee
BACKGROUND AND OBJECTIVES: Missed visits are common in office-based buprenorphine treatment (OBOT). The feasibility of text message (TM) appointment reminders among OBOT patients is unknown. METHODS: This 6-month prospective cohort study provided TM reminders to OBOT program patients (N = 93). A feasibility survey was completed following delivery of TM reminders and at 6 months. RESULTS: Respondents reported that the reminders should be provided to all OBOT patients (100%) and helped them to adhere to their scheduled appointment (97%)...
August 11, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28797822/mental-health-nurses-emotions-exposure-to-patient-aggression-attitudes-to-and-use-of-coercive-measures-cross-sectional-questionnaire-survey
#17
Rahul Jalil, Jorg W Huber, Judith Sixsmith, Geoffrey L Dickens
BACKGROUND: Mental health nurses are exposed to patient aggression, and required to manage and de-escalate aggressive incidents; coercive measures such as restraint and seclusion should only be used as a last resort. An improved understanding of links between nurses' exposure to aggression, attitudes to, and actual involvement in, coercive measures, and their emotions (anger, guilt, fear, fatigue, sadness), could inform preparation and education for prevention and management of violence...
July 31, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28796560/facial-emotion-decoding-in-patients-with-parkinson-s-disease
#18
Marco De Risi, Giancarlo Di Gennaro, Angelo Picardi, Sara Casciato, Liliana G Grammaldo, Alfredo D'Aniello, Deborah Lanni, Stefano Meletti, Nicola Modugno
PURPOSE: In line with the growing attention on non-motor symptoms and disturbance of affective and emotional processing in Parkinson's disease, we aimed to study different aspects of facial emotion expression evaluation in a group of PD without cognitive decline in treatment with common antiparkinsonian drugs, matched for sex, age, and education with healthy subjects. MATERIALS AND METHODS: The study was conducted on 30 patients (13 male; mean age: 63.3±6.7; mean age of disease onset: 56...
August 10, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28795433/schwann-cell-dedifferentiation-associated-demyelination-leads-to-exocytotic-myelin-clearance-in-inflammatory-segmental-demyelination
#19
So Young Jang, Byeol-A Yoon, Yoon Kyung Shin, Seoug Hoon Yun, Young Rae Jo, Yun Young Choi, Meejung Ahn, Taekyun Shin, Joo In Park, Jong Kuk Kim, Hwan Tae Park
Schwann cells (SCs), which form the peripheral myelin sheath, have the unique ability to dedifferentiate and to destroy the myelin sheath under various demyelination conditions. During SC dedifferentiation-associated demyelination (SAD) in Wallerian degeneration (WD) after axonal injury, SCs exhibit myelin and junctional instability, down-regulation of myelin gene expression and autophagic myelin breakdown. However, in inflammatory demyelinating neuropathy (IDN), it is still unclear how SCs react and contribute to segmental demyelination before myelin scavengers, macrophages, are activated for phagocytotic myelin digestion...
August 10, 2017: Glia
https://www.readbyqxmd.com/read/28792318/sadness-of-a-lonely-death
#20
Tracey Ann Miller
I remember my first experience as a shy, inexperienced 17-year-old.I washed a lady who had died and who had no family or even next of kin. I did a property list and all that she had in her possession were spectacles, dentures and a pair of underpants.
August 9, 2017: Nursing Standard
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