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https://www.readbyqxmd.com/read/29782959/targeting-central-%C3%AE-2-receptors-ameliorates-streptozotocin-induced-neuroinflammation-via-inhibition-of-glycogen-synthase-kinase3-pathway-in-mice
#1
Nora O Abdel Rasheed, Nesrine S El-Sayed, Aiman S El-Khatib
Alzheimer's disease (AD) is portrayed by progressive cognitive decline and pathological deposition of amyloid plaques as well as neurofibrillary tangles. Most of AD cases are sporadic, resulting from overlap of various environmental and genetic factors. Intra-cerebroventricular injection of streptozotocin (STZ) leads to insulin resistance brain state accompanied by memory decline, oxidative stress, and neuro-degeneration which mimic the pathologies associated with sporadic Alzheimer's disease (SAD). In the current study, protective effects of formoterol in STZ-induced SAD were studied...
May 18, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29782379/the-dysfunction-of-processing-emotional-faces-in-schizophrenia-revealed-by-expression-related-visual-mismatch-negativity
#2
Guimei Yin, Shenglin She, Lun Zhao, Yingjun Zheng
To investigate the emotional face processing in patients with schizophrenia, the preattentive automatic processing of emotional faces in individuals with schizophrenia was compared with that of age-matched healthy control group as indexed by the expressional mismatch negativity (EMMN) elicited by facial expressions. Compared with neutral faces as standard stimuli, deviant emotional faces elicited posterior EMMN between 150 and 500 ms after stimuli onset, with larger amplitudes for sad than happy deviant faces...
May 18, 2018: Neuroreport
https://www.readbyqxmd.com/read/29782309/in-memoriam-assistant-professor-kre%C3%A5-imir-kostovi%C3%A4-md-phd-16-october-1969-15-october-2017
#3
Branka Marinović
On a Sunday afternoon almost six months ago, we were deeply moved by the news that our Krešimir is no longer with us. The sad news spread from Sarajevo with the speed only most horrible and saddest news can achieve. And everybody who was reached by these news wondered whether it was possible and whether it was true. Because our professor Kostović left us a day before his 48th birthday. Krešimir Kostović was born on the 16th October 1969 in Zagreb, where he completed primary and secondary education. He enrolled at the University of Zagreb School of Medicine in 1988, and got his medical degree in 1995...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29782141/in-situ-assembly-of-well-dispersed-ag-nanoparticles-throughout-electrospun-alginate-nanofibers-for-monitoring-human-breath-smart-fabrics
#4
Jun Zhang, Xiao-Xiong Wang, Bin Zhang, Seeram Ramakrishna, Miao Yu, Jian-Wei Ma, Yun-Ze Long
Alginate nanofibers assembled with sliver nanoparticles throughout the whole nanofiber were fabricated by three steps including electrospinning of Na-alginate nanofibers, ion exchange between the sodium and silver ions, and in situ reduction of silver nanoparticles. The content, distribution and size of the nanoparticles are controllable by tuning reaction conditions. Ag/alginate nanofibers exhibit good humidity sensitivity in a wide humidity range from ambient RH (20%) to 85% RH. Interestingly, these humidity sensors can be attached to a 3M-9001V mask for monitoring human breath during exercise and emotion changes, and this smart exhibits accurate and continuous human-breath tracking no matter how fast or slow as well as how deep or shallow...
May 21, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29781824/symptom-experience-and-self-rated-physical-functioning-in-patients-with-ovarian-cancer-receiving-chemotherapy-a-longitudinal-study
#5
Ingvild Vistad, Milada Cvancarova, Guro Lindviksmoen Astrup, Tone Rustøen, Astrid H Liavaag
OBJECTIVES: In this longitudinal study, we investigated occurrence of multiple symptoms during chemotherapy in patients with ovarian cancer. We also evaluated whether self-rated physical functioning, selected demographic, and clinical variables were associated with symptom burden over time. METHODS AND MATERIALS: In total, 82 patients provided longitudinal data (4 time points) by completing questionnaires including the Memorial Symptom Assessment Scale, the Karnofsky Performance Status Scale, and the Self-Administered Comorbidity Questionnaire...
May 18, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29781649/treatment-of-social-approach-processes-in-adults-with-social-anxiety-disorder
#6
Lynn E Alden, Kristin Buhr, Melisa Robichaud, Jennifer L Trew, M Leili Plasencia
OBJECTIVE: Despite the social impairment associated with social anxiety disorder (SAD), little research has examined the impact of treatment on positive relational functioning. Accordingly, the authors conducted a treatment outcome study to evaluate a cognitive behavior therapy (CBT) regimen augmented by a relational focus (CBT-R) relative to a graduated exposure-applied relaxation (GEAR) regimen and wait list (WL) control. To examine the mechanism(s) that underlies treatment effects, they used structural equation modeling (SEM) to evaluate two potential mediators, change in judgment biases and in safety behaviors...
June 2018: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/29781648/a-mobile-app-for-social-anxiety-disorder-a-three-arm-randomized-controlled-trial-comparing-mobile-and-pc-based-guided-self-help-interventions
#7
Timo Stolz, Ava Schulz, Tobias Krieger, Alessia Vincent, Antoine Urech, Christian Moser, Stefan Westermann, Thomas Berger
OBJECTIVE: Internet-based cognitive-behavioral treatments (ICBT) have shown promise for various mental disorders, including social anxiety disorder (SAD). Most of these treatments have been delivered on desktop computers. However, the use of smartphones is becoming ubiquitous and could extend the reach of ICBT into users' everyday life. Only a few studies have empirically examined the efficacy of ICBT delivered through a smartphone app and there is no published study on mobile app delivered ICBT for SAD...
June 2018: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/29781645/sex-differences-in-emotion-recognition-evidence-for-a-small-overall-female-superiority-on-facial-disgust
#8
Hannah L Connolly, Carmen E Lefevre, Andrew W Young, Gary J Lewis
Although it is widely believed that females outperform males in the ability to recognize other people's emotions, this conclusion is not well supported by the extant literature. The current study sought to provide a strong test of the female superiority hypothesis by investigating sex differences in emotion recognition for five basic emotions using stimuli well-calibrated for individual differences assessment, across two expressive domains (face and body), and in a large sample (N = 1,022: Study 1). We also assessed the stability and generalizability of our findings with two independent replication samples (N = 303: Study 2, N = 634: Study 3)...
May 21, 2018: Emotion
https://www.readbyqxmd.com/read/29781577/-googling-gout-exploring-perceptions-about-gout-through-a-linguistic-analysis-of-online-search-activities
#9
Kayla N Jordan, James W Pennebaker, Keith J Petrie, Nicola Dalbeth
AIMS: To understand what terms people seeking information about gout use most frequently in online searches and explore the psychological and emotional tone of these searches. METHODS: A large de-identified dataset of search histories from major search engines was analyzed. Participants who searched for gout (n=1,117), arthritis (arthritis search control group, n=2,036, age and sex-matched), and a random set of age and sex-matched participants (general control group, n=2,150) were included...
May 21, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29781374/april-and-staci-could-be-predictors-of-severe-multiorgan-dysfunction-syndrome-in-sepsis
#10
Dajana F Lendak, Dunja M Mihajlović, Aleksandra S Novakov-Mikić, Jasmina M Boban, Milan Ubavić, Snežana V Brkić
Although the role of B cells in sepsis immunoregulation has become an interesting topic, there is lack of data on the role of B cell function regulators in prediction of multiorgan dysfunction syndrome (MODS). The aim of this study was to evaluate the prognostic value of A Proliferation Inducing Ligand (APRIL) and soluble Transmembrane Activator and CAML Interactor Protein (sTACI), the main B cell function regulators, in prediction of MODS development within the first 48h after admission to intensive care unit, among septic patients...
May 21, 2018: Virulence
https://www.readbyqxmd.com/read/29781341/bullying-and-attitudes-toward-masculinity-in-croatian-schools-behavioral-and-emotional-characteristics-of-students-who-bully-others
#11
Natko Gereš, Pamela Orpinas, Urelija Rodin, Danijela Štimac-Grbić, Aida Mujkić
Prevention of bullying is paramount to creating a positive and welcoming school environment. This study compared the following characteristics reported by students who had perpetrated bullying in Croatian schools and those who did not: gender, type of school, family wealth, negative emotionality, behaviors that may compromise health, and endorsement of traditional masculinity. Within the framework of the "Croatian Adolescent Masculinity Study," second and third grade students of secondary schools (equivalent to tenth and eleventh grade in the United States) in the city of Zagreb ( N = 4,072) completed a cross-sectional, paper-and-pencil survey...
May 1, 2018: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29780315/automatic-processing-of-changes-in-facial-emotions-in-dysphoria-a-magnetoencephalography-study
#12
Qianru Xu, Elisa M Ruohonen, Chaoxiong Ye, Xueqiao Li, Kairi Kreegipuu, Gabor Stefanics, Wenbo Luo, Piia Astikainen
It is not known to what extent the automatic encoding and change detection of peripherally presented facial emotion is altered in dysphoria. The negative bias in automatic face processing in particular has rarely been studied. We used magnetoencephalography (MEG) to record automatic brain responses to happy and sad faces in dysphoric (Beck's Depression Inventory ≥ 13) and control participants. Stimuli were presented in a passive oddball condition, which allowed potential negative bias in dysphoria at different stages of face processing (M100, M170, and M300) and alterations of change detection (visual mismatch negativity, vMMN) to be investigated...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29779855/transportability-of-imagery-enhanced-cbt-for-social-anxiety-disorder
#13
Peter M McEvoy, David M Erceg-Hurn, Kevin C Barber, Jessica R Dupasquier, David A Moscovitch
Pilot and open trials suggest that imagery-enhanced group cognitive behaviour therapy (CBT) is highly effective for social anxiety disorder (SAD). However, before being considered reliable and generalisable, the effects of the intervention need to be replicated by clinicians in a setting that is independent of the protocol developers. The current study compared outcomes from clients with a principal diagnosis of SAD at the Australian clinic where the protocol was developed (n = 123) to those from an independent Canadian clinic (n = 46) to investigate whether the large effects would generalise...
May 14, 2018: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29778654/music-and-cognitive-dissonance-comment-on-an-integrative-review-of-the-enjoyment-of-sadness-associated-with-music-by-tuomas-eerola-et-al
#14
Leonid Perlovsky
No abstract text is available yet for this article.
March 22, 2018: Physics of Life Reviews
https://www.readbyqxmd.com/read/29778040/violence-against-child-protection-workers-a-study-of-workers-experiences-attributions-and-coping-strategies
#15
Josianne Lamothe, Amélie Couvrette, Gabrielle Lebrun, Gabrielle Yale, Camille Roy, Stéphane Guay, Steve Geoffrion
Child protection workers (CPWs) are frequently exposed to client violence, both psychological and physical, in their line of work whether they operate in the community or in residential settings. Despite this known vulnerability, research on the subject has lagged. The current study sought to analyze CPWs' experiences with client violence, their interpretation of it, its perceived consequences and their coping strategies. Specifically, 30 CPWs working both in the community and in residential settings, took part in an in-depth, semi-structured interview...
May 16, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29777643/infertility-psychological-distress-and-coping-strategies-among-women-in-mali-west-africa-a-mixed-methods-study
#16
Rosanna F Hess, Ratchneewan Ross, John L GilillandJr
Relatively little is known about infertility and its consequences in Mali, West Africa where the context and culture are different from those of previously studied settings. This study therefore aimed to specifically examine infertility induced psychological distress and coping strategies among women in Mali. A convergent mixed-methods design-correlational cross-sectional and qualitative descriptive-guided the study. Fifty-eight infertile Malian women participated: 52 completed the Psychological Evaluation Test specific for infertility and a question on general health status, and 26 were interviewed in-depth...
March 2018: African Journal of Reproductive Health
https://www.readbyqxmd.com/read/29772688/modeling-the-population-health-impact-of-introducing-a-modified-risk-tobacco-product-into-the-u-s-market
#17
Smilja Djurdjevic, Peter N Lee, Rolf Weitkunat, Zheng Sponsiello-Wang, Frank Lüdicke, Gizelle Baker
Philip Morris International (PMI) has developed the Population Health Impact Model (PHIM) to quantify, in the absence of epidemiological data, the effects of marketing a candidate modified risk tobacco product (cMRTP) on the public health of a whole population. Various simulations were performed to understand the harm reduction impact on the U.S. population over a 20-year period under various scenarios. The overall reduction in smoking attributable deaths (SAD) over the 20-year period was estimated as 934,947 if smoking completely went away and between 516,944 and 780,433 if cMRTP use completely replaces smoking...
May 16, 2018: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/29771635/pathogenesis-based-treatments-in-primary-sjogren-s-syndrome-using-artificial-intelligence-and-advanced-machine-learning-techniques-a-systematic-literature-review
#18
Nathan Foulquier, Pascal Redou, Christophe Le Gal, Bénédicte Rouvière, Jacques-Olivier Pers, Alain Saraux
Big data analysis has become a common way to extract information from complex and large datasets among most scientific domains. This approach is now used to study large cohorts of patients in medicine. This work is a review of publications that have used artificial intelligence and advanced machine learning techniques to study physio pathogenesis-based treatments in pSS. A systematic literature review retrieved all articles reporting on the use of advanced statistical analysis applied to the study of systemic autoimmune diseases (SADs) over the last decade...
May 17, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29771563/induced-sadness-increases-persistence-in-a-simulated-slot-machine-task-among-recreational-gamblers
#19
Gaëtan Devos, Luke Clark, Pierre Maurage, Joël Billieux
Gambling may constitute a strategy for coping with depressive mood, but a direct influence of depressive mood on gambling behaviors has never been tested via realistic experimental designs in gamblers. The current study tested whether experimentally induced sadness increases persistence on a simulated slot machine task using real monetary reinforcement in recreational gamblers. Sixty participants were randomly assigned to an experimental (sadness induction) or control (no emotional induction) condition, and then performed a slot machine task consisting of a mandatory phase followed by a persistence phase...
May 2018: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/29771561/mood-selectively-moderates-the-implicit-alcohol-association-drinking-relation-in-college-student-heavy-episodic-drinkers
#20
Kristen P Lindgren, Jason J Ramirez, Reinout W Wiers, Bethany A Teachman, Jeanette Norris, Cecilia C Olin, Melissa L Gasser, Debra Kaysen, Clayton Neighbors
Multiple studies indicate that implicit alcohol-related associations (i.e., indices of relatively fast, spontaneous processes) predict drinking. An important next step is to investigate moderators of the implicit association-drinking relationship. Mood state has been proposed as a moderator of this relationship: implicit associations have been theorized to be stronger predictors of drinking under positive mood states. From the same theoretical perspective, explicit measures (indices of relatively slow, reflective processes) have been proposed to be stronger predictors of drinking under negative mood states...
May 2018: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
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