Izel M Eraslan, Monique Egberts-Brugman, Justin L Read, Lara M Voglsanger, Rasika M Samarasinghe, Lee Hamilton, Poshmaal Dhar, Richard J Williams, Leigh C Walker, Sarah Ch'ng, Andrew J Lawrence, Adam J Walker, Olivia M Dean, Andrew L Gundlach, Craig M Smith
Relaxin-family peptide 3 receptor (RXFP3) is activated by relaxin-3 in the brain to influence arousal and related functions, such as feeding and stress responses. Two transgenic mouse lines have recently been developed that co-express different fluorophores within RXFP3-expressing neurons: either yellow fluorescent protein (YFP; RXFP3-Cre/YFP mice) or tdTomato (RXFP3-Cre/tdTomato mice). To date, the characteristics of neurons that express RXFP3-associated fluorophores in these mice have only been investigated in the bed nucleus of the stria terminalis and the hypothalamic arcuate nucleus...
May 5, 2024: Biochemical Pharmacology