Richard Casaburi, Debora Merrill, Thomas Dolmage, Judith Garcia-Aymerich, Malin Fageras, Roger Goldstein, Gale Harding, Nancy Kline Leidy, Francois Maltais, Denis O'Donnell, Janos Porszasz, Luis Puente-Maestu, Stephen Rennard, Frank Sciurba, Martijn A Spruit, Ruth Tal-Singer, Kay Tetzlaff, Alex Van't Hul, Ren Yu, Alan Hamilton
Introduction: The chronic obstructive pulmonary disease (COPD) biomarker qualification consortium (CBQC) was formed under COPD Foundation management, with the goal of qualifying biomarkers and clinical outcome assessments through established regulatory processes. Within CBQC, a working group evaluated opportunities for qualification of an exercise endurance measure. In a recent publication [ Chronic Obstr Pulm Dis. 2022; 9(2):252-265], we described a conceptual framework establishing exercise endurance's direct relationship to an individual with COPD's experience of physical functioning in daily life, and that increase in exercise endurance is a patient-centered, meaningful treatment benefit...
August 31, 2022: Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation