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"Ground Glass Nodule"

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https://www.readbyqxmd.com/read/28066673/percutaneous-imaging-guided-cryoablation-for-lung-cancer
#1
REVIEW
Yi-Shi Zhang, Li-Zhi Niu, Ke Zhan, Zhong-Hai Li, Yu-Gang Huang, Yi Yang, Ji-Bing Chen, Ke-Cheng Xu
Percutaneous cryoablation under imaging guidance has been proved to be a safe and effective method for ablation and debulking of tumors, providing radical cure or palliation, as the case may be, for patients with different stages of disease. The local control rate is high with cryoablation, and the complications are usually controllable, making it a reasonable choice in lung cancer treatment. In this paper the technique and mechanism of action of cryoablation are summarized, and studies performed on the application of percutaneous cryoablation in various stages of lung cancer are reviewed...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28047572/we-fg-207b-07-feasibility-of-low-dose-lung-cancer-screening-with-a-whole-body-photon-counting-ct-first-human-results
#2
R Symons, T Cork, L Folio, D Bluemke, A Pourmorteza
PURPOSE: To evaluate the feasibility of using a whole-body photon counting detector (PCD) CT scanner for low dose lung cancer screening compared to a conventional energy integrating detector (EID) system. METHODS: Radiation dose-matched EID and PCD scans of the COPDGene 2 phantom and 2 human volunteers were acquired. Phantom images were acquired at different radiation dose levels (CTDIvol: 3.0, 1.5, and 0.75 mGy) and different tube voltages (120, 100, and 80 kVp), while human images were acquired at vendor recommended low-dose lung cancer screening settings...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28043993/safety-and-reproducibility-of-virtual-assisted-lung-mapping-a-multicentre-study-in-japan%C3%A2
#3
Masaaki Sato, Taiji Kuwata, Keiji Yamanashi, Atsushi Kitamura, Kenji Misawa, Kota Imashimizu, Masashi Kobayashi, Masaki Ikeda, Terumoto Koike, Shinji Kosaka, Ryuta Fukai, Yasuo Sekine, Noritaka Isowa, Shin Hirayama, Hiroaki Sakai, Fumiaki Watanabe, Kazuhiro Nagayama, Akihiro Aoyama, Hiroshi Date, Jun Nakajima
OBJECTIVES: Virtual-assisted lung mapping (VAL-MAP) is a preoperative bronchoscopic multispot dye-marking technique using virtual images. The purpose of this study was to evaluate the safety, efficacy and reproducibility of VAL-MAP among multiple centres. METHODS: Selection criteria included patients with pulmonary lesions anticipated to be difficult to identify at thoracoscopy and/or those undergoing sub-lobar lung resections requiring careful determination of resection margins...
January 2, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/27996227/-clinical-treatment-of-pure-ground-glass-nodule-on-chest-computed-tomography
#4
Masafumi Yamaguchi
No abstract text is available yet for this article.
2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/27991453/low-dose-lung-cancer-screening-with-photon-counting-ct-a-feasibility-study
#5
Rolf Symons, Tyler E Cork, Pooyan Sahbaee, Matthew K Fuld, Steffen Kappler, Les R Folio, David A Bluemke, Amir Pourmorteza
To evaluate the feasibility of using a whole-body photon-counting detector (PCD) CT scanner for low-dose lung cancer screening compared to a conventional energy integrating detector (EID) system. Radiation dose-matched EID and PCD scans of the COPDGene 2 phantom were acquired at different radiation dose levels (CTDIvol: 3.0, 1.5, and 0.75 mGy) and different tube voltages (120, 100, and 80 kVp). EID and PCD images were compared for quantitative Hounsfield unit (HU) accuracy, noise levels, and contrast-to-noise ratios (CNR) for detection of ground-glass nodules (GGN) and emphysema...
January 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27895963/evaluation-of-semi-automatic-segmentation-methods-for-persistent-ground-glass-nodules-on-thin-section-ct-scans
#6
Young Jae Kim, Seung Hyun Lee, Chang Min Park, Kwang Gi Kim
OBJECTIVES: This work was a comparative study that aimed to find a proper method for accurately segmenting persistent ground glass nodules (GGN) in thin-section computed tomography (CT) images after detecting them. METHODS: To do this, we first applied five types of semi-automatic segmentation methods (i.e., level-set-based active contour model, localized region-based active contour model, seeded region growing, K-means clustering, and fuzzy C-means clustering) to preprocessed GGN images, respectively...
October 2016: Healthcare Informatics Research
https://www.readbyqxmd.com/read/27824870/clinical-course-radiological-manifestations-and-outcome-of-pneumocystis-jirovecii-pneumonia-in-hiv-patients-and-renal-transplant-recipients
#7
Lukas Ebner, Laura N Walti, Andri Rauch, Hansjakob Furrer, Alexia Cusini, Andreas M J Meyer, Stefan Weiler, Uyen Huynh-Do, Johannes Heverhagen, Spyridon Arampatzis, Andreas Christe
BACKGROUND: Pneumocystis jirovecii pneumonia (PCP) is a frequent opportunistic infection in immunocompromised patients. In literature, presentation and outcome of PCP differs between patients with human immunodeficiency virus (HIV) infection and renal transplant recipients (RTRs). METHODS: We conducted a cross-sectional study of patients with PCP based on the HIV and renal transplant registries at our institution. Radiological and clinical data from all confirmed PCP cases between 2005 and 2012 were compared...
2016: PloS One
https://www.readbyqxmd.com/read/27765176/evaluation-of-a-new-ultrasound-thoracoscope-for-localization-of-lung-nodules-in-ex%C3%A2-vivo-human-lungs
#8
Hideki Ujiie, Tatsuya Kato, Hsin-Pei Hu, Suhaib Hasan, Priya Patel, Hironobu Wada, Daiyoon Lee, Kosuke Fujino, David M Hwang, Marcelo Cypel, Marc de Perrot, Andrew Pierre, Gail Darling, Thomas K Waddell, Shaf Keshavjee, Kazuhiro Yasufuku
BACKGROUND: Localization of small, nonvisible and nonpalpable nodules is challenging during video-assisted thoracoscopic surgery. We evaluated the feasibility of using a new ultrasound thoracoscope to localize nodules in resected ex vivo human lungs. METHODS: The tumor was localized and measured in its greatest dimension with a prototype ultrasound thoracoscope (XLTF-UC180; Olympus Corporation, Tokyo, Japan) at different frequencies (5.0 to 12.0 MHz) and different lung specimen states (deflated, semiinflated)...
October 17, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27666609/computer-aided-diagnosis-cad-of-subsolid-nodules-evaluation-of-a-commercial-cad-system
#9
Joseph Benzakoun, Sébastien Bommart, Joël Coste, Guillaume Chassagnon, Mathieu Lederlin, Samia Boussouar, Marie-Pierre Revel
OBJECTIVES: To evaluate the performance of a commercially available CAD system for automated detection and measurement of subsolid nodules. MATERIALS AND METHODS: The CAD system was tested on 50 pure ground-glass and 50 part-solid nodules (median diameter: 17mm) previously found on standard-dose CT scans in 100 different patients. True nodule detection and the total number of CAD marks were evaluated at different sensitivity settings. The influence of nodule and CT acquisition characteristics was analyzed with logistic regression...
October 2016: European Journal of Radiology
https://www.readbyqxmd.com/read/27659289/thin-section-computed-tomography-findings-of-lung-adenocarcinoma-with-inherent-metastatic-potential
#10
Shigeki Suzuki, Keiju Aokage, Junji Yoshida, Genichiro Ishii, Yuki Matsumura, Tomohiro Haruki, Tomoyuki Hishida, Kanji Nagai
PURPOSE: The solid component of lung ground-glass nodules on thin-section computed tomography (TSCT) reflects cancer cell progression and invasiveness. The purpose of this study was to clarify the cut-off value of preoperative TSCT findings in treating a lesion suspected of being adenocarcinoma and to recognize the timing of surgical resection for lung nodules. METHODS: We reevaluated the TSCT findings in 392 patients with clinical stage IA lung adenocarcinoma who underwent surgical resection between 2003 and 2007...
September 22, 2016: Surgery Today
https://www.readbyqxmd.com/read/27643776/how-to-define-and-display-solid-components-within-ground-glass-nodules-and-differentiate-pure-ground-glass-nodules-from-mixed-ground-glass-nodules
#11
Li Fan, Qiong Li, Yi Xiao, Yun Wang, Shi-Yuan Liu
No abstract text is available yet for this article.
October 2016: Radiology
https://www.readbyqxmd.com/read/27594146/value-of-baseline-clinical-and-ct-characteristics-for-predicting-the-progression-of-persistent-pure-ground-glass-nodule-10-mm-or-less-in-diameter
#12
Fang Wu, Zu-Long Cai, Shu-Ping Tian, Xin Jin, Rui Jing, Yue-Qing Yang, Mei Jin, Shao-Hong Zhao
Objective To explore the risk factors of the progression of persistent pure ground-glass nodule (pGGN) and make the risk stratification for pGGN 10 mm or less in diameter. Methods From June 2008 to April 2015,100 patients (108 lesions) with persistent pGGN≤10 mm in diameter were included in this study. Patients were followed up at least 1 year using thin-section computed tomography (CT). Patients' baseline clinical data and CT characteristics of pGGN were compared between progression group (size increased or/and solid component appeared) and non-progression group...
August 2016: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/27575275/value-of-ct-characteristics-in-predicting-invasiveness-of-adenocarcinoma-presented-as-pulmonary-ground-glass-nodules
#13
Hongdou Ding, Jingyun Shi, Xiao Zhou, Dong Xie, Xiao Song, Yang Yang, Zhongliu Liu, Haifeng Wang
Background Less invasive adenocarcinomas (LIAs) of the lung, including adenocarcinoma in situ (AIS) and minimally invasive adenocarcinoma (MIA), are indications of sublobar resection and has a 5-year disease-free survival rate of almost 100% after surgery. By distinguishing invasive adenocarcinoma from LIA with computed tomography (CT) characteristics, it is possible to determine the extent of resection and prognosis for patients with ground-glass nodules (GGNs) before surgery. Methods We reviewed CT and pathological findings of 728 GGNs in 645 consecutive patients who received curative lung resection in a single center...
August 30, 2016: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/27542241/preoperative-nomogram-for-identifying-invasive-pulmonary-adenocarcinoma-in-patients-with-pure-ground-glass-nodule-a-multi-institutional-study
#14
Yunlang She, Lilan Zhao, Chenyang Dai, Yijiu Ren, Junyan Zha, Huikang Xie, Sen Jiang, Jingyun Shi, Shunbin Shi, Weirong Shi, Bing Yu, Gening Jiang, Ke Fei, Yongbing Chen, Chang Chen
PURPOSE: To construct a preoperative nomogram to differentiate invasive pulmonary adenocarcinomas (IPAs) from preinvasive lesions in patients with solitary pure ground-glass nodules (GGN). METHODS: A primary cohort of patients with pathologically confirmed pulmonary solitary pure GGN after surgery were retrospectively studied at five institutions from January 2009 to September 2015. Half of the patients were randomly selected and assigned to a model-development cohort, and the remaining patients were assigned to a validation cohort...
August 11, 2016: Oncotarget
https://www.readbyqxmd.com/read/27532604/preoperative-percutaneous-transthoracic-needle-biopsy-increased-the-risk-of-pleural-recurrence-in-pathological-stage-i-lung-cancer-patients-with-sub-pleural-pure-solid-nodules
#15
Kosuke Kashiwabara, Hiroshi Semba, Shinji Fujii, Shinsuke Tsumura
We retrospectively evaluated whether preoperative percutaneous transthoracic needle biopsy (PTNB) affected the incidence of pleural recurrence in pathological stage I lung cancer patients. Pleural recurrence occurred in pure solid nodule (PSN) cases but not in ground-glass nodule cases, as evaluated using thin-section computed tomographic imaging. When the cases were restricted to sub-pleural PSN, the incidence of recurrence tended to be higher in a PTNB group (63 patients diagnosed by PTNB) than in a non-PTNB group (86 patients diagnosed by transbronchial biopsy or intraoperative diagnosis) (25% vs...
September 13, 2016: Cancer Investigation
https://www.readbyqxmd.com/read/27499970/visceral-pleural-invasion-in-lung-adenocarcinoma-%C3%A2-3-cm-with-ground-glass-opacity-a-clinical-pathological-and-radiological-study
#16
Li-Lan Zhao, Hui-Kang Xie, Li-Ping Zhang, Jun-Yan Zha, Fang-Yu Zhou, Ge-Ning Jiang, Chang Chen
BACKGROUND: Visceral pleural invasion (VPI) had been demonstrated as an aggressive sign in non-small cell lung cancers (NSCLC). However, its incidence and clinical relevance in early lung cancer showing ground glass nodules (GGNs) has not been clarified. METHODS: All consecutive surgically treated patients with solitary GGNs between 2009 and 2013 were reviewed retrospectively. Inclusion criteria were defined as lesions ≤3 cm with pleura abutting on computed tomography (CT) scan and pathologically confirmed NSCLC...
July 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27454944/solitary-pulmonary-capillary-hemangioma-of-adult-cases-clinicopathologic-characteristics-as-an-unrecognized-entity
#17
Hirotsugu Hashimoto, Atsushi Kurata, Masachika Fujiwara, Kei Hara, Jun Matsumoto, Masashi Kusakabe, Keisei Tachibana, Tamaki Nashiro, Yuichi Terado, Masaaki Akahane, Kazuhiro Usui, Yoshio Suzuki, Haruhiko Kondo, Hiroshi Kamma, Masahiko Kuroda, Hajime Horiuchi
Solitary pulmonary capillary hemangioma (SPCH) is a rare disease, first described about autopsy cases in 2000 and about surgically resected cases in 2006. To date, only 9 surgically resected cases have been published in English. Here, we report 7 original cases with surgery (median age, 54 y; 4 females, 2 never-smokers). All patients were asymptomatic, and all nodules were detected by computed tomography (CT). The median (range) size of nodule was 11 (8 to 16) mm. Six of 7 cases showed the part-solid nodule appearance and 1 showed pure ground-glass nodule appearance in CT findings...
October 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27255399/subsolid-pulmonary-nodule-morphology-and-associated-patient-characteristics-in-a-routine-clinical-population
#18
Onno M Mets, Pim A de Jong, Ernst Th Scholten, Kaman Chung, Bram van Ginneken, Cornelia M Schaefer-Prokop
OBJECTIVES: To determine the presence and morphology of subsolid pulmonary nodules (SSNs) in a non-screening setting and relate them to clinical and patient characteristics. METHODS: A total of 16,890 reports of clinically obtained chest CT (06/2011 to 11/2014, single-centre) were searched describing an SSN. Subjects with a visually confirmed SSN and at least two thin-slice CTs were included. Nodule volumes were measured. Progression was defined as volume increase exceeding the software interscan variation...
February 2017: European Radiology
https://www.readbyqxmd.com/read/27249174/maximum-intensity-projection-and-computer-aided-detection-algorithms-as-stand-alone-reader-devices-in-lung-cancer-screening-using-different-dose-levels-and-reconstruction-kernels
#19
Lukas Ebner, Justus E Roos, Jared D Christensen, Tomas Dobrocky, Lars Leidolt, Barbara Brela, Verena C Obmann, Sonya Joy, Adrian Huber, Andreas Christe
OBJECTIVE: The objective of our study was to evaluate lung nodule detection rates on standard and microdose chest CT with two different computer-aided detection systems (SyngoCT-CAD, VA 20, Siemens Healthcare [CAD1]; Lung CAD, IntelliSpace Portal DX Server, Philips Healthcare [CAD2]) as well as maximum-intensity-projection (MIP) images. We also assessed the impact of different reconstruction kernels. MATERIALS AND METHODS: Standard and microdose CT using three reconstruction kernels (i30, i50, i70) was performed with an anthropomorphic chest phantom...
August 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27198242/101pd-preoperative-nomogram-for-identifying-invasive-pulmonary-adenocarcinoma-in-patients-with-pure-ground-glass-nodule-a-multi-institutional-study
#20
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