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"Ground Glass Nodule"

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https://www.readbyqxmd.com/read/28639833/predictive-ct-features-of-visceral-pleural-invasion-by-t1-sized-peripheral-pulmonary-adenocarcinomas-manifesting-as-subsolid-nodules
#1
Su Yeon Ahn, Chang Min Park, Yoon Kyung Jeon, Hyungjin Kim, Jong Hyuk Lee, Eui Jin Hwang, Jin Mo Goo
OBJECTIVE: The objective of our study was to determine whether visceral pleural invasion (VPI) of T1-sized peripheral pulmonary adenocarcinomas manifesting as subsolid nodules (SSNs) abutting the pleural surface or associated with pleural tags can be predicted. MATERIALS AND METHODS: Our study population consisted of 188 T1-sized peripheral pulmonary adenocarcinomas that appeared as SSNs (24 pure ground-glass nodules [GGNs] and 164 part-solid nodules) and underwent surgical resection between January 2007 and December 2013...
June 22, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28629453/three-dimensional-substructure-measurements-for-the-differential-diagnosis-of-ground-glass-nodules
#2
Mingzheng Peng, Gang Yu, Chengzhong Zhang, Cuidi Li, Jinwu Wang
BACKGROUND: We analyzed the differences between maximum and peak computed tomography (CT) numbers (M-P), respectively representing the densities of the solid center and the main periphery of ground-glass nodules (GGNs), and the average change in M-P velocity (V(M-P)) during follow-up to differentiate between pre-invasive (PIA) and invasive adenocarcinoma (IAC). METHODS: Data of 102 patients were retrospectively collected and analyzed in our study including 43 PIAs and 59 IACs...
June 19, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28625634/imaging-features-of-tsct-predict-the-classification-of-pulmonary-preinvasive-lesion-minimally-and-invasive-adenocarcinoma-presented-as-ground-glass-nodules
#3
Yinan Liu, Hui Sun, Fei Zhou, Chunxia Su, Guanghui Gao, Shengxiang Ren, Caicun Zhou, Zhemin Zhang, Jingyun Shi
OBJECTIVES: To comprehensively investigate the role of thin section computed tomography(TSCT) features to distinguish invasive adenocarcinoma(IA) from preinvasive or minimally invasive adenocarcinoma(MIA) appearing as pure or mixed ground glass nodules (pGGNs, mGGNs), and to distinguish adenocarcinoma in situ (AIS) from atypical adenomatous hyperplasia (AAH) in pGGNs. MATERIALS AND METHODS: Three hundred thirteen patients with 334 pathologically diagnosed GGNs according to the 2011 IASLC/ATS/ERS classification were included into this study...
June 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28616728/the-relationship-of-cancer-characteristics-and-patient-outcome-with-time-to-lung-cancer-diagnosis-after-an-abnormal-screening-ct
#4
Sushilkumar K Sonavane, Paul Pinsky, Jubal Watts, David S Gierada, Reginald Munden, Satinder P Singh, Hrudaya Nath
PURPOSE: The National Lung Screening Trial (NLST) demonstrated a reduction in lung cancer and all-cause mortality with low-dose CT (LDCT) screening. The aim of our study was to examine the time to diagnosis (TTD) of lung cancer in the LDCT arm of the NLST and assess its relationship with cancer characteristics and survival. METHODS: The subjects (N = 462) with a positive baseline screen and subsequent lung cancer diagnosis within 3 years were evaluated by data and image review to confirm the baseline abnormality...
June 14, 2017: European Radiology
https://www.readbyqxmd.com/read/28616268/tumor-invasiveness-defined-by-iaslc-ats-ers-classification-of-ground-glass-nodules-can-be-predicted-by-quantitative-ct-parameters
#5
Qian-Jun Zhou, Zhi-Chun Zheng, Yong-Qiao Zhu, Pei-Ji Lu, Jia Huang, Jian-Ding Ye, Jie Zhang, Shun Lu, Qing-Quan Luo
BACKGROUND: To investigate the potential value of CT parameters to differentiate ground-glass nodules between noninvasive adenocarcinoma and invasive pulmonary adenocarcinoma (IPA) as defined by IASLC/ATS/ERS classification. METHODS: We retrospectively reviewed 211 patients with pathologically proved stage 0-IA lung adenocarcinoma which appeared as subsolid nodules, from January 2012 to January 2013 including 137 pure ground glass nodules (pGGNs) and 74 part-solid nodules (PSNs)...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28608997/natural-history-and-clinical-characteristics-of-multiple-pulmonary-nodules-with-ground-glass-opacity
#6
Yuki Sato, Daichi Fujimoto, Takeshi Morimoto, Keiichiro Uehara, Kazuma Nagata, Ichiro Sakanoue, Hiroshi Hamakawa, Yutaka Takahashi, Yukihiro Imai, Keisuke Tomii
BACKGROUND AND OBJECTIVE: Ground glass nodules (GGNs) are frequently encountered in the lungs. We report the natural history and characteristics of multiple GGNs, and propose a management plan for patients with multiple GGNs. METHODS: We retrospectively analysed patients with GGNs that met the following criteria: (i) GGN diameter of 3 cm or less, (ii) ground glass opacity proportion of 50% or more and (iii) observation without treatment for ≥6 months. We evaluated size changes in computed tomography images...
June 13, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28576745/lung-adenocarcinoma-manifesting-as-pure-ground-glass-nodules-correlating-ct-size-volume-density-and-roundness-with-histopathologic-invasion-and-size
#7
Benedikt H Heidinger, Kevin R Anderson, Ursula Nemec, Daniel B Costa, Sidhu P Gangadharan, Paul A VanderLaan, Alexander A Bankier
HYPOTHESIS: To quantify the relation between computed tomography (CT) size, volume, density, and roundness of lung adenocarcinomas (AC) manifesting as pure ground glass nodules (pGGNs) on CT, and to correlate these parameters with histologic features of invasiveness. METHODS: From 2005 to 2015, 63 ACs manifesting as pGGNs on CT were surgically resected at our institution. CT size was measured, and roundness, volumes and densities were computed. CT parameters were correlated to age and gender, as well as to size and number of invasive foci, and to histologic AC subcategories...
May 30, 2017: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/28575398/carbon-dioxide-insuf%C3%AF-ation-and-thoracoscopic-ultrasonography-image-of-pure-ground-glass-nodule
#8
Hirofumi Uehara, Atsushi Yasuda, Hiroshi Kondo, Masafumi Kawamura
Thoracic surgeons frequently encounter early lung cancer showing a pure ground-glass nodule. Although thoracoscopic wedge resection is used extensively, it cannot be easily located for surgical procedures. Thoracoscopic ultrasonography is a real-time and less invasive technique for small lung lesion localization during thoracoscopic surgery. However, this technique has not been widely adopted because residual air in the lung results in poor ultrasound images. A 64-year-old woman was found to have pure ground-glass nodule...
May 29, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28523166/a-novel-hybrid-technique-for-localization-of-subcentimeter-lung-nodules
#9
Xuguang Pang, Liang Xue, Jiemin Chen, Jianyong Ding
BACKGROUND: It is technically challenging to locate non-visible, non-palpable subcentimeter ground-glass nodules (GGNs) of lung during video-assisted thoracic surgery (VATS). Computed tomography (CT)-guided marking of small pulmonary nodules using microcoils has been reported to be a practical method of preoperative localization, whereas dislodgement of microcoils remains to be a bothersome complication. The objective of this study was to assess the viability and effectiveness of a newly developed hybrid technique, which combines induced controllable pneumothorax and CT-guided microcoil marking procedure to reduce the risk of microcoil dislodgement...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449455/the-many-facets-of-diagnostic-bronchoscopy-for-pulmonary-ground-glass-nodules
#10
EDITORIAL
Christine Chavez, Takehiro Izumo
No abstract text is available yet for this article.
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28386719/ct-and-histopathologic-characteristics-of-lung-adenocarcinoma-with-pure-ground-glass-nodules-10-mm-or-less-in-diameter
#11
Fang Wu, Shu-Ping Tian, Xin Jin, Rui Jing, Yue-Qing Yang, Mei Jin, Shao-Hong Zhao
OBJECTIVE: To evaluate CT and histopathologic features of lung adenocarcinoma with pure ground-glass nodule (pGGN) ≤10 mm in diameter. METHODS: CT appearances of 148 patients (150 lesions) who underwent curative resection of lung adenocarcinoma with pGGN ≤10 mm (25 atypical adenomatous hyperplasias, 42 adenocarcinoma in situs, 38 minimally invasive adenocarcinomas, and 45 invasive pulmonary adenocarcinomas) were analyzed for lesion size, density, bubble-like sign, air bronchogram, vessel changes, margin, and tumour-lung interface...
April 6, 2017: European Radiology
https://www.readbyqxmd.com/read/28386717/co-registration-of-pre-operative-ct-with-ex-vivo-surgically-excised-ground-glass-nodules-to-define-spatial-extent-of-invasive-adenocarcinoma-on-in-vivo-imaging-a-proof-of-concept-study
#12
Mirabela Rusu, Prabhakar Rajiah, Robert Gilkeson, Michael Yang, Christopher Donatelli, Rajat Thawani, Frank J Jacono, Philip Linden, Anant Madabhushi
OBJECTIVE: To develop an approach for radiology-pathology fusion of ex vivo histology of surgically excised pulmonary nodules with pre-operative CT, to radiologically map spatial extent of the invasive adenocarcinomatous component of the nodule. METHODS: Six subjects (age: 75 ± 11 years) with pre-operative CT and surgically excised ground-glass nodules (size: 22.5 ± 5.1 mm) with a significant invasive adenocarcinomatous component (>5 mm) were included...
April 6, 2017: European Radiology
https://www.readbyqxmd.com/read/28338535/lung-cancers-associated-with-cystic-airspaces-natural-history-pathologic-correlation-and-mutational-analysis
#13
Florian J Fintelmann, Jesaja K Brinkmann, William R Jeck, Fabian M Troschel, Subba R Digumarthy, Mari Mino-Kenudson, Jo-Anne O Shepard
PURPOSE: The aim of the study was to investigate the natural history of non-small cell lung cancers (NSCLCs) associated with cystic airspaces, including histopathology and molecular analysis. MATERIALS AND METHODS: A total of 34,801 computed tomographic (CT) scans of 2954 patients diagnosed with NSCLC between 2010 and 2015 were evaluated for association with a cystic airspace. Characteristics on serial CT, 18F-fludeoxyglucose positron emission tomography, and pathologic analysis were recorded...
May 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28328859/single-stage-nonintubated-uniportal-thoracoscopic-resection-of-synchronous-bilateral-pulmonary-nodules-after-coil-labeling-a-case-report-and-literature-review
#14
Miao Zhang, Tao Wang, You-Wei Zhang, Wen-Bin Wu, Heng Wang, Rong-Hua Xu
RATIONALE: Preoperative localization of small pulmonary nodules is essential for precise resection, besides, the optimal treatment for pulmonary nodules is controversial and the prognosis without surgery is uncertain. PATIENT CONCERNS: Herein we present a patient with compromised pulmonary function harboring synchronous triple ground-glass nodules located separately in different pulmonary lobes. DIAGNOSES: The pathological diagnosis of the nodules were chronic inflammation, inflammatory pseudotumor and atypical adenomatous hyperplasia, respectively...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28296757/radiological-prediction-of-tumor-invasiveness-of-lung-adenocarcinoma-on-thin-section-ct
#15
Masahiro Yanagawa, Takeshi Johkoh, Masayuki Noguchi, Eiichi Morii, Yasushi Shintani, Meinoshin Okumura, Akinori Hata, Maki Fujiwara, Osamu Honda, Noriyuki Tomiyama
To evaluate thin-section computed tomography (CT) (TSCT) features that differentiate adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), and invasive adenocarcinoma (IVA), and to determine the size of solid portion on CT that correlates to pathological invasive components. Forty-eight patients were included. Nodules were classified into ground-glass nodule (GGN), part-solid, solid, and heterogeneous. Visual density of GGNs was subjectively evaluated using reference standard images: faint GGN (Ga), <-700 Hounsfield unit (HU); intermediate GGN (Gb), from -700 to -400 HU; dense GGN (Gc), >-400 HU; and mixed (Ga + Gb, Ga + Gc, and Gb + Gc)...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28267551/quantitative-ct-analysis-of-pulmonary-pure-ground-glass-nodule-predicts-histological-invasiveness
#16
Qiong Li, Li Fan, En-Tao Cao, Qing-Chu Li, Ya-Feng Gu, Shi Yuan Liu
OBJECTIVE: To assess whether quantitative computed tomography (CT) can help predict histological invasiveness of pulmonary adenocarcinoma appearing as pure ground glass nodules (pGGNs). METHODS: A total of 110 pulmonary pGGNs were retrospectively evaluated, and pathologically classified as pre-invasive lesions, minimally invasive adenocarcinoma (MIA) and invasive pulmonary adenocarcinoma (IPA). Maximum nodule diameters, largest cross-sectional areas, volumes, mean CT values, weights, and CT attenuation values at the 0th,2th,5th, 25th, 50th,75th, 95th, 98th and100th percentiles on histogram, as well as 2th to 98th, 5th to 95th, 25th to 75th,and 0th to 100thslopes, respectively, were compared among the three groups...
April 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28243892/micropapillary-histological-subtype-in-lung-adenocarcinoma-of-2%C3%A2-cm-or-less-impact-on-recurrence-and-clinical-predictors
#17
Yukihiro Yoshida, Jun-Ichi Nitadori, Aya Shinozaki-Ushiku, Jiro Sato, Tempei Miyaji, Takuhiro Yamaguchi, Masashi Fukayama, Jun Nakajima
OBJECTIVE: This study examined the clinical and radiological characteristics of adenocarcinoma having the micropapillary histological subtype. METHODS: We included 233 patients who were operated from 2001 to 2012 for lung adenocarcinoma of 2 cm or less. The pathology was reviewed according to the 2015 WHO classification. We defined adenocarcinoma with a micropapillary component as adenocarcinoma in which the area of the micropapillary histological subtype exceeded 5% of the tumor...
May 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28186249/correlation-between-radiological-and-pathological-features-of-operated-ground-glass-nodules
#18
Ludovic Fournel, Harry Etienne, Audrey Mansuet Lupo, Diane Damotte, Alexandra Rouquette, Marie-Pierre Revel, Claude Guinet, Marco Alifano, Jean-François Regnard
No abstract text is available yet for this article.
February 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28119328/what-is-the-radiological-definition-of-part-solid-tumour-in-lung-cancer-%C3%A2
#19
Takeshi Matsunaga, Kenji Suzuki, Kazuya Takamochi, Shiaki Oh
OBJECTIVES: The method of evaluating ground glass opacity (GGO) on thin-section computed tomographic (CT) scans is an issue of debate in early lung cancer. The term 'part-solid tumour' is frequently misused, and there is no consensus for its definition. METHODS: A retrospective study was conducted on 775 consecutive patients with resected lung adenocarcinoma of clinical stage IA between 2008 and 2013. Part-solid tumours (PSTs) having a ground glass component and consolidation were divided into two categories using the radiological criterion of a consolidation-to-tumour (C/T) ratio of 0...
February 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28104995/spontaneous-rupture-of-hepatic-epithelioid-hemangioendothelioma-a-case-report
#20
Jun-Wu Yang, Yong Li, Kai Xie, Wei Dong, Xian-Tong Cao, Wei-Dong Xiao
Hepatic epithelioid hemangioendothelioma (HEH) is a rare tumor of vascular endothelial origin. Spontaneous rupture of HEH is a life-threatening complication and is extremely rare. HEH has variable malignant potential, and the clinical diagnosis remains challenging. Here we report a case of HEH with spontaneous rupture. A 44-year-old man presented with constant cutting pains over the right upper abdomen after eating. He had hemoptysis 11 d previously. Diagnostic abdominal puncture demonstrated active bleeding...
January 7, 2017: World Journal of Gastroenterology: WJG
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