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https://www.readbyqxmd.com/read/28445795/a-novel-approach-to-calculating-small-intestine-length-based-on-magnetic-resonance-enterography
#1
Nicole A Wilson, Hyung-Soon Park, Kyoung Soub Lee, Lauren K Barron, Brad W Warner
BACKGROUND: Bowel length is an important factor in the management of patients with intestinal failure and short bowel syndrome (SBS). However, it is difficult to accurately measure the length of the small intestine. Our purpose was to demonstrate the feasibility of a dedicated software algorithm for calculating small intestine length based on magnetic resonance enterography (MRE) images. STUDY DESIGN: A custom algorithm for image thresholding, wall-identification, segmentation, and path extraction was designed and implemented...
April 23, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28444216/dietary-metabolites-derived-from-gut-microbiota-critical-modulators-of-epigenetic-changes-in-mammals
#2
Mohd Iqbal Bhat, Rajeev Kapila
The mammalian gastrointestinal tract harbors trillions of commensal microorganisms, collectively known as the microbiota. The microbiota is a critical source of environmental stimuli and, thus, has a tremendous impact on the health of the host. The microbes within the microbiota regulate homeostasis within the gut, and any alteration in their composition can lead to disorders that include inflammatory bowel disease, allergy, autoimmune disease, diabetes, mental disorders, and cancer. Hence, restoration of the gut flora following changes or imbalance is imperative for the host...
April 22, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/28443583/retrograde-cerebral-air-embolism-in-a-patient-with-intestinal-necrosis-a-case-report
#3
Onur Taydaş, Mehmet Ruhi Onur, Erhan Akpınar
BACKGROUND: Cerebral venous air embolism (CVAE) is a severe clinical condition related to unfavoured outcome in patients with neurological impairment. CVAE may occur secondary to arterial or venous interventions. A rare mechanism of CVAE is retrograde embolism that is characterized by gas flow in a direction opposite to that of the normal blood flow. CASE REPORT: A 69-year-old female was admitted to our hospital with shortness of breath and abdominal pain. Abdominal computed tomography (CT) revealed intramural gas in the bowel and free gas in the mesenteric veins and portal vein...
April 13, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28437455/effect-of-a-probiotic-beverage-consumption-enterococcus-faecium-crl-183-and-bifidobacterium-longum-atcc-15707-in-rats-with-chemically-induced-colitis
#4
Larissa Sbaglia Celiberto, Raquel Bedani, Naiara Naiana Dejani, Alexandra Ivo de Medeiros, José Antonio Sampaio Zuanon, Luis Carlos Spolidorio, Maria Angela Tallarico Adorno, Maria Bernadete Amâncio Varesche, Fábio Carrilho Galvão, Sandro Roberto Valentini, Graciela Font de Valdez, Elizeu Antonio Rossi, Daniela Cardoso Umbelino Cavallini
BACKGROUND: Some probiotic strains have the potential to assist in relieving the symptoms of inflammatory bowel disease. The impact of daily ingestion of a soy-based product fermented by Enterococcus faecium CRL 183 and Lactobacillus helveticus 416 with the addition of Bifidobacterium longum ATCC 15707 on chemically induced colitis has been investigated thereof within a period of 30 days. METHODS: Colitis was induced by dextran sulfate sodium. The animals were randomly assigned into five groups: Group C: negative control; Group CL: positive control; Group CLF: DSS with the fermented product; Group CLP: DSS with the non-fermented product (placebo); Group CLS: DSS with sulfasalazine...
2017: PloS One
https://www.readbyqxmd.com/read/28437000/magnetically-guided-capsule-endoscopy
#5
REVIEW
Naveen Shamsudhin, Vladimir I Zverev, Henrik Keller, Salvador Pane, Peter W Egolf, Bradley J Nelson, Alexander M Tishin
Wireless capsule endoscopy (WCE) is a powerful tool for medical screening and diagnosis, where a small capsule is swallowed and moved by means of natural peristalsis and gravity through the human gastrointestinal (GI) tract. The camera-integrated capsule allows for visualization of the small intestine, a region which was previously inaccessible to classical flexible endoscopy. As a diagnostic tool, it allows to localize the sources of bleedings in the middle-part of the gastrointestinal tract and to identify diseases such as inflammatory bowel disease (Crohn's disease), Polyposis-Syndrome and tumors...
April 24, 2017: Medical Physics
https://www.readbyqxmd.com/read/28436060/pneumatosis-intestinalis-in-a-cohort-of-children-with-neurological-impairment-a-patient-group-with-a-management-dilemma
#6
Karim Awad, Melissa Short, Anindya Niyogi, Gareth Hosie, Alok Godse
AIM: Pneumatosis intestinalis (PI) is uncommon in school-age children. We studied a cohort of neurologically impaired school-age children with PI to formulate an optimum management plan. METHODS: We retrospectively studied all school-age children who were referred to paediatric surgeons with radiological evidence of PI identified between 2011 and 2015. We analysed data on patient demographics, medications, feeding, associated comorbidities, presentation, investigations and treatments...
April 24, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28434083/predictors-of-a-successful-outcome-for-infants-with-short-bowel-syndrome-a-30-year-single-institution-experience
#7
Tatsuru Kaji, Kazuhiko Nakame, Seiro Machigashira, Takafumi Kawano, Ryuta Masuya, Waka Yamada, Koji Yamada, Shun Onishi, Tomoe Moriguchi, Koshiro Sugita, Motoi Mukai, Satoshi Ieiri
PURPOSE: Short-bowel syndrome (SBS) is associated with high morbidity and mortality. We conducted this study to establish the predictors of survival and weaning off parenteral nutrition (PN). METHODS: We reviewed the medical records of 16 SBS infants treated at our institution within a 30-year period. SBS was defined as a residual small-bowel length (RSBL) of <75 cm. Loss of the ileocecal valve (ICV), cholestasis (D-Bil >2.0 mg/dl), enterostomy, and RSBL were all evaluated...
April 22, 2017: Surgery Today
https://www.readbyqxmd.com/read/28429671/ethanolamine-metabolism-in-the-mammalian-gastrointestinal-tract-mechanisms-patterns-and-importance
#8
J Zhou, X Xiong, K Wang, L Zou, D Lv, Y Yin
Nutritional exchanges and cooperation between bacteria in the gastrointestinal tract and the mammalian host play an important role in health and disease. Ethanolamine is an essential dietary lipid nutrient for animals and is abundant in both intestinal and bacterial cell membranes. Ethanolamine can be utilized by intestinal eukaryotic cells via the cytidine phosphoethanolamine pathway for de novo synthesis of phosphatidylethanolamine, and certain bacteria are able to catabolize it as a major carbon and/or nitrogen source with the help of ethanolamine utilization proteins...
March 31, 2017: Current Molecular Medicine
https://www.readbyqxmd.com/read/28429130/long-term-outcome-of-sacral-neuromodulation-for-chronic-refractory-constipation
#9
Yasuko Maeda, Michael A Kamm, Carolynne J Vaizey, Klaus E Matzel, Claes Johansson, Harald Rosen, Cornelius G Baeten, Søren Laurberg
PURPOSE: Sacral neuromodulation has been reported as a treatment for severe idiopathic constipation. This study aimed to evaluate the long-term effects of sacral neuromodulation by following patients who participated in a prospective, open-label, multicentre study up to 5 years. METHODS: Patients were followed up at 1, 3, 6, 12, 24, 36, 48 and 60 months. Symptoms and quality of life were assessed using bowel diary, the Cleveland Clinic constipation score and the Short Form-36 quality-of-life scale...
April 20, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/28426474/pouch-related-symptoms-and-quality-of-life-in-patients-with-ileal-pouch-anal-anastomosis
#10
Edward L Barnes, Hans H Herfarth, Robert S Sandler, Wenli Chen, Elizabeth Jaeger, Van M Nguyen, Amber R Robb, Michael D Kappelman, Christopher F Martin, Millie D Long
BACKGROUND: Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) has become the standard surgical treatment for the majority of patients with inflammatory bowel disease (IBD) who require colectomy. We evaluated the prevalence of pouch-related symptoms among the Crohn's and Colitis Foundation of America Partners cohort and the effect of pouch-related symptoms on Patient-Reported Outcome Measurement Information System measures. METHODS: We performed analyses nested in the Crohn's and Colitis Foundation of America Partners cohort...
April 19, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28426457/race-differences-in-initial-presentation-early-treatment-and-1-year-outcomes-of-pediatric-crohn-s-disease-results-from-the-improvecarenow-network
#11
Jennifer L Dotson, Michele Cho, Josh Bricker, Michael D Kappelman, Deena J Chisolm, Gitit Tomer, Wallace V Crandall
BACKGROUND: Racially disparate care has been shown to contribute to suboptimal health care outcomes for minorities. Using the ImproveCareNow network, we investigated differences in management and outcomes of pediatric patients with Crohn's disease at diagnosis and 1-year postdiagnosis. METHODS: ImproveCareNow is a learning health network for pediatric inflammatory bowel disease. It contains prospective, longitudinal data from outpatient encounters. This retrospective study included all patients with Crohn's disease ≤21 years, September 2006 to October 2014, with the first recorded encounter ≤90 days from date of diagnosis and an encounter 1 year ±60 days...
May 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28425133/fecal-microbiota-signatures-of-adult-patients-with-different-types-of-short-bowel-syndrome
#12
Yuhua Huang, Feilong Guo, Yousheng Li, Jian Wang, Jieshou Li
BACKGROUND AND AIM: Short bowel syndrome (SBS) is a common cause of intestinal failure and can be divided into three types depending on intestinal anatomy. Gut dysbiosis has been observed in pediatric SBS patients and is associated with impaired outcome. Little is known about the changes in gut microbiota of adult SBS patients. Therefore, we aim to characterize the fecal microbiota of adult patients with different types of SBS. METHODS: Fifteen fecal samples from healthy controls and adult patients with type II or type III SBS were collected (five in each group)...
April 19, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28422869/effects-of-jianpi-qingchang-decoction-on-the-quality-of-life-of-patients-with-ulcerative-colitis-a-randomized-controlled-trial
#13
Yan-Cheng Dai, Lie Zheng, Ya-Li Zhang, Xuan Chen, De-Liang Chen, Zhi-Peng Tang
This study aims to determine the effects of the Jianpi Qingchang decoction (JQD) on the quality of life (QOL) of patients with spleen deficiency and dampness-heat syndrome ulcerative colitis (UC).A total of 120 active UC patients with spleen deficiency and dampness-heat syndrome were enrolled into this study. These patients were randomly divided into 2 groups: test group and control group (n = 60, each group). Patients in the test group were treated with JQD, while patients in control group were treated with 5-amino salicylic acid...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28422369/what-impact-do-questionnaire-length-and-monetary-incentives-have-on-mailed-health-psychology-survey-response
#14
Kathryn A Robb, Lauren Gatting, Jane Wardle
OBJECTIVES: Response rates to health-related surveys are declining. This study tested two strategies to improve the response rate to a health psychology survey mailed through English general practices: (1) sending a shortened questionnaire and (2) offering a monetary incentive to return a completed questionnaire. DESIGN: Randomized controlled trial. METHODS: Adults (n = 4,241) aged 45-59 years, from four General Practices in South-East England, were mailed a survey on attitudes towards bowel cancer screening...
April 19, 2017: British Journal of Health Psychology
https://www.readbyqxmd.com/read/28421909/management-of-intra-abdominally-translocated-contraceptive-devices-is-surgery-the-only-way-to-treat-this-problem
#15
Mustafa Gazi Uçar, Fatih Şanlıkan, Tolgay Tuyan Ilhan, Ahmet Göçmen, Çetin Çelik
This study was a multi-centre retrospective review of patients with uterine perforation caused by intrauterine contraceptive devices (IUDs). A total of 15 patients were registered, in a seven year period. Among them, five were asymptomatic and the rest were symptomatic. Asymptomatic patients were managed conservatively, except in one case in which the patient requested surgery because she also wanted a tubal ligation. Symptomatic patients all underwent surgery. All the surgeries were elective and all the surgical procedures were initiated laparoscopically...
May 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28421251/defining-the-ultrasound-longitudinal-natural-history-of-newly-diagnosed-pediatric-small-bowel-crohn-disease-treated-with-infliximab-and-infliximab-azathioprine-combination-therapy
#16
Jonathan R Dillman, Soudabeh Fazeli Dehkordy, Ethan A Smith, Michael A DiPietro, Ramon Sanchez, Vera DeMatos-Maillard, Jeremy Adler, Bin Zhang, Andrew T Trout
BACKGROUND: Little is known about changes in the imaging appearances of the bowel and mesentery over time in either pediatric or adult patients with newly diagnosed small bowel Crohn disease treated with anti-tumor necrosis factor-alpha (anti-TNF-α) therapy. OBJECTIVE: To define how bowel ultrasound findings change over time and correlate with laboratory inflammatory markers in children who have been newly diagnosed with pediatric small bowel Crohn disease and treated with infliximab...
April 18, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28420945/controversies-and-recent-developments-of-the-low-fodmap-diet
#17
Peta Hill, Jane G Muir, Peter R Gibson
The low-fermentable oligo-, di-, and monosaccharide and polyol (FODMAP) diet is a 2-phased intervention, with strict reduction of all slowly absorbed or indigestible short-chain carbohydrates (ie, FODMAPs) followed by reintroduction of specific FODMAPs according to tolerance. The efficacy of the elimination phase of the FODMAP diet is well established, but the success of maintaining this diet has been shown in only a few observational studies. How the efficacy of the low-FODMAP diet compares with that of other therapies has received limited attention, but recent studies have shown this diet to be comparable or superior to diets that address eating style and choice of food as well as to gut hypnotherapy...
January 2017: Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28415670/case-control-study-of-the-efficacy-of-retrogastric-roux-en-y-choledochojejunostomy
#18
Xin-Wei Yang, Jun-Yi Chen, Wen-Liang Yan, Jing Du, Zhi-Jian Wen, Xing-Zhou Yan, Ping-Hua Yang, Jue Yang, Bao-Hua Zhang
The traditional, retrocolic/antegastric Roux-en-Y choledochojejunostomy is technically complicated, and the incidence of postoperative complications remains high. Here we report the outcome of 59 consecutively treated patients (study group, SG) that underwent a new choledochojejunostomy method in which the jejunal loop is passed behind the antrum pyloricum (retrogastric route). A retrospective comparison was made between this group of patients and 187 patients (control group, CG) that underwent conventional Roux-en-Y choledochojejunostomy (antegastric route)...
March 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28414674/a-clot-possibly-due-to-loss-of-tnf-%C3%AE-supression
#19
J Broussard, M Berlinger, D Lauret
INTRODUCTION: Inflammation and venous thrombosis enjoy a close Relationship. We present a patient who had multiple DVTs following the discontinuation of anti- TNF-α therapy. CASE: A 34 year old African American female with a history of multiple DVT's, miscarriages, and reported Crohn's disease presented with shortness of breath. In the Emergency Department, CTA showed bilateral pulmonary emboli. The patient had been off adalimumab for one year and reported abdominal pain with 6-7 non-bloody bowel movements daily...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28413300/anorectal-agenesis-with-rectovaginal-fistula-a-rare-regional-variant
#20
Subhasis Roy Choudhury, Niyaz Ahmed Khan, Pinaki Ranjan Debnath, Partap Singh Yadav, Shalu Shah, Rajiv Chadha
AIMS AND OBJECTIVES: The anatomical types of female anorectal malformation (ARM) are complex and include several rare and regional variants. The aim of this report is to highlight the diagnosis and management of cases of anorectal agenesis with rectovaginal fistula (RVF). MATERIALS AND METHODS: This is a retrospective chart review of cases of RVF who underwent definitive surgery between November 2000 and September 2016 in a single institution. RESULTS: Of the 244 female patients with anorectal anomalies treated in our institution over a 16-year period, there were 15 cases of RVF with anorectal agenesis giving it an incidence of 6%...
April 2017: Journal of Indian Association of Pediatric Surgeons
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