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Upper GI surgery

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https://www.readbyqxmd.com/read/29439836/hospital-variation-and-the-impact-of-postoperative-complications-on-the-use-of-perioperative-chemo-radio-therapy-in-resectable-gastric-cancer-results-from-the-dutch-upper-gi-cancer-audit
#1
M G Schouwenburg, L A D Busweiler, N Beck, D Henneman, S Amodio, M I van Berge Henegouwen, A Cats, R van Hillegersberg, J W van Sandick, B P L Wijnhoven, M W J Wouters, G A P Nieuwenhuijzen
BACKGROUND: Dutch national guidelines on the diagnosis and treatment of gastric cancer recommend the use of perioperative chemotherapy in patients with resectable gastric cancer. However, adjuvant chemotherapy is often not administered. The aim of this study was to evaluate hospital variation on the probability to receive adjuvant chemotherapy and to identify associated factors with special attention to postoperative complications. METHODS: All patients who received neoadjuvant chemotherapy and underwent an elective surgical resection for stage IB-IVa (M0) gastric adenocarcinoma between 2011 and 2015 were identified from a national database (Dutch Upper GI Cancer Audit)...
January 12, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29434711/endoscopic-management-of-foreign-bodies-in-the-upper-gastrointestinal-tract-an-analysis-of-846-cases-in-china
#2
Fangfang Yuan, Xiaowei Tang, Wei Gong, Lei Su, Yali Zhang
Foreign body ingestion is a relatively common occurrence, which may lead to morbidity and mortality. The aim of the present study was to report the experience of management of upper gastrointestinal foreign bodies by endoscopy in a large center. All patients who presented at the Department of Gastroenterology at Nanfang Hospital (Guangzhou, China) with complaints regarding upper gastrointestinal (GI) foreign body ingestion from December 1987 to December 2013. Hospital medical charts and endoscopic records were examined to evaluate etiology, treatment, and outcomes for these patients...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29428692/routine-contrast-imaging-after-bariatric-surgery-and-the-effect-on-hospital-length-of-stay
#3
Uzma Rahman, Salvatore Docimo, Aurora D Pryor, Andrew Bates, Nabeel R Obeid, Konstantinos Spaniolas
BACKGROUND: Although multiple studies demonstrate that routine postoperative contrast studies have a low yield in diagnosing patients with early gastrointestinal (GI) leak after bariatric surgery, the practice pattern is unknown. Additionally, routine imaging may hinder procedural pathways that lead to accelerated postoperative discharge. OBJECTIVES: To report on the nationwide use of routine upper GI studies (UGI) and evaluate the effect on hospital resource utilization...
January 3, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29412834/targeted-intestinal-delivery-of-incretin-secretagogues-towards-new-diabetes-and-obesity-therapies
#4
Fiona M Gribble, Claire L Meek, Frank Reimann
A new strategy under development for the treatment of type 2 diabetes and obesity is to mimic some of the effects of bariatric surgery by delivering food-related stimuli to the distal gastrointestinal tract where they should enhance the release of gut hormones such as glucagon-like peptide-1 (GLP-1) and peptideYY (PYY). Methods include inhibition of food digestion and absorption in the upper GI tract, or oral delivery of stimuli in capsules or pelleted form to protect them against gastric degradation. A variety of agents have been tested in humans using capsules, microcapsules or pellets, delivering nutrients, bile acids, fatty acids and bitter compounds...
February 2018: Peptides
https://www.readbyqxmd.com/read/29346827/efficacy-and-complications-of-submucosal-tunneling-endoscopic-resection-for-upper-gastrointestinal-submucosal-tumors-and-exploration-for-influencing-factors
#5
Shunzhe Song, Xu Wang, Shen Zhang, Yanxia Li, Xiaonan Zhang, Xufang Chu
BACKGROUND:  Submucosal tunneling endoscopic resection (STER) has emerged as a feasible technique for resecting upper gastrointestinal (GI) tract submucosal tumors (SMTs) through natural orifice transluminal endoscopic surgery. STER reduces the risk of postoperative perforation and abdominal infections and promotes rapid wound healing. The aim of this meta-analysis was to evaluate the safety and efficacy of STER for small (≤ 3.5 cm) upper GI SMTs and explore the potential factors influencing STER's efficacy and complication rate...
January 18, 2018: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29343478/treatment-of-gastrointestinal-bleeding-with-idarucizumab-in-a-patient-receiving-dabigatran
#6
Jennifer Mourafetis, Norman Doctor, Simon Leung
PURPOSE: A case report describing use of idarucizumab for dabigatran reversal without the use of hemostatic agents in a patient who developed acute upper gastrointestinal (GI) bleeding while receiving triple antithrombotic therapy is presented. SUMMARY: A 77-year-old man with a complex cardiac history presented to the emergency room with chief complaints of black tarry stools and low blood pressures for 4 days. His past medical history included recent percutaneous coronary intervention (PCI) and drug-eluting stent (DES) placement, atrial fibrillation, hypertension, hyperlipidemia, coronary artery disease, coronary artery bypass graft surgery, stage 3 chronic kidney disease, and cholecystectomy...
January 17, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29340823/endoscopic-perforations-what-are-the-indications-for-surgery
#7
Diane Mege, Laura Beyer-Berjot, Walid Ezzedine, Anderson Loundou, Jean-Charles Grimaud, Marc Barthet, Stéphane Berdah
BACKGROUND: Despite their low occurrence, endoscopic perforations (EPs) are concerning. Some predictive factors have been identified, and EP management is debated, whether non-surgical (medical and/or endoscopic) or surgical. The objective was to elaborate a predictive score for surgical management of EP. METHODS: All the patients addressed for upper and lower EP, except oesophageal EP, were retrospectively included (2004-2015). Demographic data, endoscopic features (indication, location, type), clinical, biological and radiological presentations of EP were reviewed...
January 16, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29286026/-quality-of-life-of-patients-with-complicated-reflux-esophagitis-followed-antireflux-surgery
#8
A F Chernousov, T V Khorobrykh, F P Vetshev, T I Ionova, D Mugadzaveta, S V Osminin, T P Nikitina
AIM: To analyze quality of life of patients with complicated reflux-esophagitis followed antireflux surgery. MATERIAL AND METHODS: The trial enrolled 200 patients who underwent surgical treatment at the Burdenko Faculty Surgery Clinic of Sechenov First Moscow State Medical University for complicated reflux esophagitis from 2008 to 2015. Inclusion criteria were long-standing reflux esophagitis irresistible to conservative treatment, hiatal hernia with shortening of the esophagus and/or peptic stricture and/or Barrett's esophagus...
2017: Khirurgiia
https://www.readbyqxmd.com/read/29282515/impact-of-the-weekday-of-surgery-on-outcome-in-gastric-cancer-patients-who-underwent-d2-gastrectomy
#9
Felix Berlth, K Messerle, P S Plum, S-H Chon, J von Ambüren, A Hohn, M Dübbers, C J Bruns, S P Mönig, E Bollschweiler, A H Hölscher, H Alakus
BACKGROUND: The impact of the weekday of surgery in major elective cases of the upper-GI has been discussed controversially. The objective of this study was to assess whether weekday of surgery influences outcome in patients undergoing D2-gastrectomy. MATERIALS AND METHODS: Patients who underwent D2-gastrectomy for gastric adenocarcinoma between 1996 and 2016 were included. Weekday of surgery was recognized, and subgroups were analyzed regarding clinical and histopathological differences...
December 28, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29282382/massive-upper-and-lower-gi-bleed-from-simultaneous-primary-al-amyloidosis-of-the-stomach-and-transverse-colon-in-a-patient-with-multiple-myeloma
#10
Zubair Khan, Umar Darr, Anas Renno, Abhinav Tiwari, Aijaz Sofi, Ali Nawras
Symptomatic primary (amyloid light-chain or AL) amyloidosis of the gastrointestinal (GI) tract is very rare. Most of the patients with symptomatic involvement of the GI tract present with altered motility, malabsorption, or bleeding. We report a case of gastric and colonic amyloidosis on anticoagulation presenting with massive upper and lower GI bleeding. A 67-year-old lady known to have multiple myeloma and AL amyloidosis on rivaroxaban presented with massive upper GI bleeding. Esophagogastroduodenoscopy showed a mass lesion (3 × 7 cm) located along the greater curvature in the body/antrum with active bleeding...
September 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29273212/factors-contributing-to-variation-in-the-use-of-multimodality-treatment-in-patients-with-gastric-cancer-a-dutch-population-based-study
#11
N Beck, L A D Busweiler, M G Schouwenburg, M Fiocco, A Cats, F E M Voncken, B P L Wijnhoven, M I van Berge Henegouwen, M W J M Wouters, J W van Sandick
BACKGROUND: Substantial variation in the use of (neo) adjuvant treatment in patients with gastric cancer exists. The aim of this study was to identify underlying (organizational and process) factors associated with the use of perioperative therapy. PATIENTS AND METHODS: Patients with resectable gastric cancer who underwent surgery between 2012 and 2014 were selected from the Dutch Upper gastrointestinal Cancer Audit (DUCA). The proportion of perioperatively treated patients was defined per hospital...
December 13, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29260002/profile-of-extrahepatic-portal-venous-obstruction-among-children-in-central-india
#12
Mayank Jain, Jenisha Jain, Gauri Rao Passi, Kamna Jain, Shikhar Jain
Introduction: There is a paucity of data regarding the clinical profile of children with extrahepatic portal venous obstruction (EHPVO) from Central India. Material and methods: Retrospective analysis of 30 children with EHPVO treated between 2002 and 2012. Results: The median age of presentation was 12.5 years (range 5-14 years) and median duration of symptoms was 3.2 years (range 0.3-10 years). Home delivery was noted in 30 cases (100%), umbilical sepsis in 8 (27%) and history of cow dung application over the umbilical cord in 2 cases (6...
December 2017: Clinical and Experimental Hepatology
https://www.readbyqxmd.com/read/29218673/results-of-endoscopic-vacuum-assisted-closure-device-for-treatment-of-upper-gi-leaks
#13
Marc Bludau, Hans F Fuchs, Till Herbold, Martin K H Maus, Hakan Alakus, Felix Popp, Jessica M Leers, Christiane J Bruns, Arnulf H Hölscher, Wolfgang Schröder, Seung-Hun Chon
BACKGROUND: Esophageal perforations and postoperative leakage of esophagogastrostomies are considered to be life-threatening conditions due to the potential development of mediastinitis and consecutive sepsis. Vacuum-assisted closure (VAC) techniques, a well-established treatment method for superficial infected wounds, are based on a negative pressure applied to the wound via a vacuum-sealed sponge. Endoluminal VAC (E-VAC) therapy as a treatment for GI leakages in the rectum was introduced in 2008...
December 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29216840/over-the-scope-clip-pre-mounted-onto-a-double-balloon-enteroscope-for-fast-and-successful-closure-of-post-emr-jejunal-perforation-case-report
#14
Flaminia Purchiaroni, Takeshi Nakajima, Taku Sakamoto, Seiichiro Abe, Yutaka Saito
BACKGROUND: Familial adenomatous polyposis (FAP) is a rare, autosomal dominant disease clinically characterized by the early onset of many adenomatous polyps throughout the colon, which turn into colon cancer, if left untreated. In FAP patients, polyps can also occur in the upper gastrointestinal (GI) tract, especially in the duodenum. Adenomas beyond duodenum are rare and mostly located in the proximal jejunum and distal ileum. The management of such polyps can be either surgical or endoscopic, depending on the features of the polyp, Spigelman stage and patient's clinical conditions...
December 8, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/29158179/prognostic-factors-affecting-outcomes-in-patients-with-malignant-gi-bleeding-treated-with-a-novel-endoscopically-delivered-hemostatic-powder
#15
Rapat Pittayanon, Rungsun Rerknimitr, Alan Barkun
BACKGROUND AND AIM: Endoscopic hemostatic techniques remain poorly effective for GI tumor bleeding. We assessed Tc-325 (Hemospray) for this indication and determined possible predictors of decreased recurrent bleeding and improved 6-month survival in affected patients. METHODS: This retrospective study identified 99 patients with active malignant GI bleeding (primary or metastatic) treated with Tc-325. Eleven patients were excluded because of incomplete data. Data on patient characteristics and possible predictive factors of early (72-hour) and delayed (7, 14 and 30-day) recurrent bleeding, as well as six-month survival, were collected...
November 17, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29124121/patients-comorbidities-reduce-the-clinical-value-of-emergency-colonoscopy-results-of-a-retrospective-cohort-study
#16
Cristiano Cremone, Anouk Esch, Charlotte Gagniere, Alessandro Fugazza, Faria Mesli, Michael Levy, Aurelien Amiot, Alexis Laurent, Yann LeBaleur, Francois Hemery, Nicolas De'Angelis, Francesco Brunetti, Iradj Sobhani
Background and study aims:  Urgent endoscopy is often used to diagnose and sometimes treat acute upper gastrointestinal syndromes (hemorrhage, toxic ingestion, and occlusion). However, its suitability concerning the management of lower gastrointestinal conditions in emergency circumstances is controversial. Patients and methods:  We studied the role of emergency colonoscopy in diagnosis and treatment of all consecutive patients presenting with acute lower gastrointestinal symptoms referred to our hospital on an emergency basis...
November 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/29102872/shoulder-balance-in-lenke-type-2-adolescent-idiopathic-scoliosis-should-we-fuse-to-the-second-thoracic-vertebra
#17
Huiliang Yang, Gi Hye Im, Bowen Hu, Lei Wang, Chunguang Zhou, Limin Liu, Yueming Song
OBJECTIVES: There are many different systems recommending upper instrumented vertebra (UIV) for Lenke type 2 adolescent idiopathic scoliosis (AIS), several of which suggest that all Lenke type 2 AIS patients should be fused to the second thoracic vertebra (T2). However, all previously proposed UIV selecting systems do not accurately predict postoperative shoulder balance. We investigated whether fusing to T2 could prevent postoperative shoulder imbalance and identified circumstances under which to fuse up to T2...
October 31, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29031177/giant-gastric-lipoma-presenting-as-gi-bleed-enucleation-or-resection
#18
Salah Termos, Ossama Reslan, Omar Alqabandi, Abdullah AlDuwaisan, Saud Al-Subaie, Khalifa Alyatama, Mohammad Alali, Ahmad AlSaleh
INTRODUCTION: Gastric lipomas are unusual benign lesions and account for less than 1% of all tumours of the stomach and 5% of all gastrointestinal lipomas (Thompson et al.2003; Fernandez et al. 1983 [1,2]). Although predominantly asymptomatic and indolent; they may present with gastric outlet obstruction and upper gastrointestinal (GI) bleeding owing to size and ulceration. Only a few cases have been reported, presenting large in size with massive GI bleeding (Alcalde Escribano et al...
October 6, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28991077/surveillance-of-duodenal-polyposis-in-familial-adenomatous-polyposis-should-the-spigelman-score-be-modified
#19
EDITORIAL
Isabelle Sourrouille, Jérémie H Lefèvre, Conor Shields, Chrystelle Colas, Jerôme Bellanger, Benoît Desaint, Francois Paye, Emmanuel Tiret, Yann Parc
BACKGROUND: Duodenal polyposis is a manifestation of adenomatous polyposis that predisposes to duodenal or ampullary adenocarcinoma. Duodenal polyposis is monitored by upper GI endoscopies and may require iterative resections and prophylactic radical surgical treatment when malignancy is threatening. OBJECTIVE: The purpose of this study was to evaluate severity scoring for surveillance and treatment in a large series of duodenal polyposis. DESIGN: From 1982 to 2014, every patient surveyed by upper GI endoscopies for duodenal polyposis was included...
November 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28987713/radiographic-measurement-of-intestinal-length-among-children-with-short-bowel-syndrome-retrospective-determination-remains-problematic
#20
Cristine S Velazco, Brenna S Fullerton, Joseph A Brazzo, Charles R Hong, Tom Jaksic, Carol E Barnewolt
PURPOSE: Small bowel length is the most reliable predictor of enteral independence in pediatric short bowel syndrome. Retrospectively measured bowel lengths on upper GI with small bowel follow-through (UGI/SBFT) were compared to operative measurements. METHODS: A pediatric radiologist and surgical trainees blinded to operative measurements retrospectively analyzed UGI/SBFT studies using the digital radiography curved measurement tool. Children with SBS and severe intestinal failure (parenteral nutrition >90days) at a multidisciplinary intestinal failure program 2002-2015 were included...
September 5, 2017: Journal of Pediatric Surgery
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