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SAF system

P Saumya-Rajesh, J Krithikadatta, N Velmurugan, C Sooriaprakas
AIM: This randomized controlled trial compared the incidence of post-instrumentation pain associated with Mtwo rotary NiTi files and the self-adjusting file system following canal shaping and cleaning. METHODOLOGY: Following sample size estimation, a total of 130 patients were randomized into two groups based on selection criteria [group Mtwo and group SAF (self-adjusting file)]. Root canal treatment was carried out in two appointments. The teeth were endodontically treated with the appropriate allotted systems following the similar clinical parameters...
September 23, 2016: International Endodontic Journal
Ali Keleş, Hatice Alçin, Manoel D Sousa-Neto, Marco A Versiani
INTRODUCTION: The purpose of this ex vivo study was to evaluate the percentage reduction of accumulated hard tissue debris (AHTD) in the mesial root canal system of mandibular molars under different final irrigation regimens by means of micro-computed tomographic imaging. METHODS: Sixty curved mesial roots of mandibular molars with 2 independent canals joint apically by an isthmus (Vertucci type II) were selected. Specimens were scanned at a resolution of 12.5 μm, anatomically matched, and distributed into 3 groups (n = 20) according to the preparation protocol: Self-Adjusting File (SAF; ReDent Nova, Ra'anana, Israel), Reciproc (VDW GmbH, Munich, Germany), and Revo-S (Micro-Mega, Besançon, France) systems...
September 9, 2016: Journal of Endodontics
Hannes Hagström, Patrik Nasr, Mattias Ekstedt, Stergios Kechagias, Per Stål, Pierre Bedossa, Rolf Hultcrantz
BACKGROUND AND AIMS: A new score for the histological severity of nonalcoholic fatty liver disease (NAFLD), called SAF (Steatosis, Activity and Fibrosis) has been developed. We aimed to evaluate the impact of this score on overall mortality. METHODS: We used data from 139 patients with biopsy-proven NAFLD. All biopsies were graded according to the SAF scoring system and disease severity was classified as mild, moderate or severe. Causes of death were extracted from a national, population-based register...
September 10, 2016: Scandinavian Journal of Gastroenterology
Aliye Kamalak, Ismail Uzun, Hakan Arslan, Ali Keleş, Ezgi Doğanay, Cangül Keskin, Merve Akçay
OBJECTIVE: Additional cleaning techniques and devices are required to remove maximum amount of residual filling material, which might limit disinfection of root canal system during retreatment. This study aimed to compare fracture resistance of roots when self-adjusting file (SAF), photon-induced photoacoustic streaming (PIPS), passive ultrasonic irrigation (PUI), erbium-doped yttrium aluminum garnet (Er:YAG), or neodymium-doped yttrium aluminum garnet (Nd:YAG) lasers are applied following the use of retreatment files in endodontics...
October 2016: Photomedicine and Laser Surgery
M Munteanu, D Tiniakos, Q Anstee, F Charlotte, G Marchesini, E Bugianesi, M Trauner, M Romero Gomez, C Oliveira, C Day, J-F Dufour, S Bellentani, Y Ngo, S Traussnig, H Perazzo, O Deckmyn, P Bedossa, V Ratziu, T Poynard
BACKGROUND: Blood tests of liver injury are less well validated in non-alcoholic fatty liver disease (NAFLD) than in patients with chronic viral hepatitis. AIMS: To improve the validation of three blood tests used in NAFLD patients, FibroTest for fibrosis staging, SteatoTest for steatosis grading and ActiTest for inflammation activity grading. METHODS: We pre-included new NAFLD patients with biopsy and blood tests from a single-centre cohort (FibroFrance) and from the multicentre FLIP consortium...
October 2016: Alimentary Pharmacology & Therapeutics
Yuanqing Ma, Aleš Benda, Philip R Nicovich, Katharina Gaus
Supercritical angle fluorescence (SAF) detection combines the axial discrimination and exquisite signal-to-noise ratio of total internal reflection fluorescence (TIRF) with the lateral discrimination and convenience of confocal excitation. This combination makes SAF ideal for fluorescence correlation spectroscopy (FCS) on membranes and other structures in close proximity to the coverslip. Here we report a straightforward modification of a commercial microscope to implement SAF FCS and demonstrate in both model supported lipid bilayers and cellular systems that this approach shows an increase in signal from membrane-bound fluorophores relative to fluorophores in solution, benchmarked against line-scanning FCS...
April 1, 2016: Biomedical Optics Express
E J N L Silva, V M Ferreira, C C Silva, Herrera, G De-Deus, B P Gomes
AIM: To compare the effectiveness of large apical preparations and complementary canal preparation with the Self Adjusting File (SAF) in removing endotoxins from the root canal of teeth with apical periodontitis. METHODOLOGY: Ten single-rooted and single-canaled teeth with post-treatment apical periodontitis were selected. Endotoxin samples were taken after the removal of the root filling (S1), after chemomechanical preparation (CMP) using 2.5% NaOCl and an R25 file (S2), after CMP using 2...
July 12, 2016: International Endodontic Journal
Ghada N El-Sarnagawy, Amal Saf Hafez
The decision of intubation and mechanical ventilation in poisoned patients with impaired consciousness can be a difficult task. The present study aimed to evaluate the power of Glasgow Coma Scale (GCS), acute physiology and chronic health evaluation (APACHE II), rapid acute physiology score (RAPS) and rapid emergency medicine score (REMS) at admission in predicting the need of intubation and mechanical ventilation in drug overdose patients with disturbed consciousness level (DCL). This prospective observational study was conducted on 104 poisoned patients who were admitted to Tanta Toxicological Unit with a DCL...
June 23, 2016: Human & Experimental Toxicology
Bosu Jeong, Chang Hee Jung, Yong-Ho Lee, Il-Hyung Shin, Hansuk Kim, Soo-Jin Bae, Dae-Sic Lee, Eun Seok Kang, Uk Kang, Jong Jin Kim, Joong-Yeol Park
Optical measurement of skin auto-fluorescence (SAF), most likely emanating from accumulated advanced glycation end-products (AGEs), has been proposed for the noninvasive diagnosis of glucose intolerance in clinical settings. Here, we developed a novel imaging system with transmission geometry for SAF measurement and compared its diagnostic performance in a Korean population.
June 2016: Diabetes Research and Clinical Practice
Nishant K Vyavahare, Srinidhi Surya Raghavendra, Niranjan N Desai
BACKGROUND: Complete cleaning of the root canal is the goal for ensuring success in endodontics. Removal of debris plays an important role in achieving this goal. In spite of advancements in instrument design, apical extrusion of debris remains a source of inflammation in the periradicular region. AIM: To comparatively evaluate the amount of apically extruded debris with V-Taper, ProTaper Next, and the self-adjusting File (SAF) system. MATERIALS AND METHODS: Sixty-four extracted human mandibular teeth with straight root canals were taken...
May 2016: Journal of Conservative Dentistry: JCD
P Amoroso-Silva, M P Alcalde, M A Hungaro Duarte, G de Deus, R Ordinola-Zapata, L G Freire, B C Cavenago, I G de Moraes
AIM: To assess the effect of 90º-oscillatory instrumentation with hand files on the following morphological parameters (volume, surface area and uninstrumented surface) in C-shaped root canals after instrumentation using a single-file reciprocation system (Reciproc; VDW, Munich, Germany) and a Self-Adjusting File System (SAF; ReDent Nova, Ra'anana, Israel). METHODOLOGY: Twenty mandibular second molars with C-shaped canals and C1 canal configurations were divided into two groups (n = 10) and instrumented with Reciproc and SAF instruments...
May 19, 2016: International Endodontic Journal
Ajinkya M Pawar, Mansing Pawar, Zvi Metzger, Bhagyashree Thakur
AIM: This study evaluated whether using supplementary files for removing root canal filling residues after ProTaper Universal Retreatment files (RFs) increased the debris extrusion apically. MATERIALS AND METHODS: Eighty mandibular premolars with single root and canal were instrumented with ProTaper Universal rotary system (SX-F3) and obturated. The samples were divided randomly into four groups (n = 20). Group 1 served as a control; only ProTaper Universal RFs D1-D3 were used, and the extruded debris was weighed...
March 2016: Journal of Conservative Dentistry: JCD
Aziz Mahmoudzadeh, Afshin Mohsenifar, Tavoos Rahmani-Cherati
Macrophages are effector cells in the innate and adaptive immune systems and in situ exist within three-dimensional (3-D) microenvironments. As there has been an increase in interest in the use of 3-D scaffolds to mimic natural microenvironments in vitro, this study examined the impact on cultured mice peritoneal macrophages using standard 2-D plates as compared to 3-D collagen-chitosan scaffolds. Here, 2-D and 3-D cultured macrophages were evaluated for responses to lipopolysaccharide (LPS), dexamethasone (Dex), BSA (bovine serum albumin), safranal (herbal component isolated from safranal [Saf]) and Alyssum homolocarpum mucilage (A...
July 2016: Journal of Immunotoxicology
A Kfir, D Elkes, A Pawar, A Weissman, I Tsesis
OBJECTIVES: The objective of this study is to determine the potential for microcracks in the radicular dentin of first maxillary premolars using three different mechanized endodontic instrumentation systems. METHODS: Eighty extracted maxillary first premolars with two root canals and no externally visible microcracks were selected. Root canal instrumentation was performed with either the ProTaper file system, the WaveOne primary file, or the self-adjusting file (SAF)...
March 30, 2016: Clinical Oral Investigations
Pierre Bedossa, Keyur Patel
Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum of histopathologic features, ranging from isolated hepatic steatosis, to steatohepatitis with evidence of hepatocellular injury and fibrosis, to cirrhosis. The diagnosis and determination of NAFLD prognosis requires clinical and histopathologic assessments. Liver biopsy still is regarded as the reference for differentiating steatosis (NAFL) from nonalcoholic steatohepatitis, for staging hepatic fibrosis, and for identifying NAFLD in patients with other chronic liver disease...
June 2016: Gastroenterology
G B Leoni, M A Versiani, Y T Silva-Sousa, J F B Bruniera, J D Pécora, M D Sousa-Neto
AIM: To evaluate the efficacy of four final irrigation protocols on the reduction of hard-tissue debris accumulated within the mesial root canal system of mandibular first molars using micro-CT analysis. METHODOLOGY: Forty mesial roots of mandibular molars with a single and continuous isthmus connecting the mesiobuccal and mesiolingual canals (Vertucci's Type I configuration) were selected and scanned at a resolution of 8.6 μm. Canals were enlarged sequentially using WaveOne Small and Primary instruments activated in reciprocating motion without intracanal irrigation to allow debris to accumulate within the mesial root canal system...
March 18, 2016: International Endodontic Journal
Fatih Cakici, Elif B Cakici, Funda Fundaoglu Küçükekenci
PURPOSE: To compare the amount of apically extruded debris during root canal retreatment using ProTaper retreatment system (Dentsply Maillefer, Ballaigues, Switzerland), ProTaper retreatment system with Self-Adjusting File (SAF) system (ReDent-Nova, Ra'anana, Israel), Mtwo retreatment system (VDW, Munich, Germany), Mtwo retreatment system with SAF instruments. METHODS: In total, 72 extracted human mandibular incisor teeth were used. All root canals were prepared with ProTaper universal (Dentsply Maillefer) up to F2 file and filled with gutta percha and AH plus sealer using cold lateral condensation before being assembled randomly into 4 groups (n = 18 each)...
February 2016: International Journal of Artificial Organs
Ratyakshi Nain, Dhirendra Singh, Manjeet Jassal, Ashwini K Agrawal
The effect of incorporation of rigid zinc oxide (ZnO) nanostructures on carbonization behavior of electrospun special acrylic fiber grade poly(acrylonitrile) (PAN-SAF) nanofibers was investigated. ZnO nanorods with high aspect ratios were incorporated into a PAN-N,N-dimethylformamide system and the composite nanofibers reinforced with aligned ZnO rods up to 50 wt% were successfully electrospun, and subsequently, carbonized. The morphology and the structural analysis of the resultant carbon nanofibers revealed that the rigid ZnO nanorods, present inside the nanofibers, possibly acted as scaffolds (temporary support structures) for immobilization of polymer chains and assisted in uniform heat distribution...
February 21, 2016: Nanoscale
Sinan Yürüker, Melahat Görduysus, Selen Küçükkaya, Emel Uzunoğlu, Can Ilgın, Orhan Gülen, Behram Tuncel, Mehmet Ömer Görduysus
INTRODUCTION: The aim of this study was to estimate the remaining amount of residual filling materials in root canals after retreatment using ProTaper Universal Retreatment (PTUR) files (Dentsply Maillefer, Ballaigues, Switzerland) alone or with the additional use of the Self-Adjusting File (SAF; ReDent-Nova, Ra'anana, Israel), Reciproc (VDW, Munich, Germany), or Hedström-files (H-file; VDW, Antaeos, Munich, Germany) with volumetric estimation using the stereologic method via cone-beam computed tomographic images...
March 2016: Journal of Endodontics
Jonathan Rodrigues, Carrie Caruthers, Roua Azmeh, Mark S Dykewicz, Raymond G Slavin, Alan P Knutsen
Fungi cause a wide spectrum of fungal diseases of the upper and lower airways. There are three main phyla involved in allergic fungal disease: (1) Ascomycota (2) Basidiomycota (3) Zygomycota. Allergic fungal rhinosinusitis (AFRS) causes chronic rhinosinusitis symptoms and is caused predominantly by Aspergillus fumigatus in India and Bipolaris in the United States. The recommended treatment approach for AFRS is surgical intervention and systemic steroids. Allergic bronchopulmonary aspergillosis (APBA) is most commonly diagnosed in patients with asthma or cystic fibrosis...
2016: Expert Review of Clinical Immunology
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