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https://www.readbyqxmd.com/read/29222991/salivary-immune-proteins-monitoring-can-help-detection-of-binge-and-chronic-alcohol-drinkers-preliminary-findings
#1
Napoleon Waszkiewicz, Beata Galińska-Skok, Anna Zalewska, Sławomir Dariusz Szajda, Krzysztof Zwierz, Magdalena Więdłocha, Agata Szulc
BACKGROUND: We compared effects of binge and chronic alcohol drinking on oral health and salivary immunity proteins. METHODS: The study involved males: 13 healthy social-drinking (C), 10 alcohol-dependent after chronic alcohol-intoxication (A), and 8 binge-drinkers after a single binge-drinking session (B). We compared periodontal/dental state and salivary immune proteins (lactoferrin -Lf, lysozyme -Lz, oral peroxidase -OPO, immunoglobulin A -IgA) in all groups...
December 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29222585/-extranodal-abdominal-lymphomas
#2
REVIEW
T F Weber, S Dietrich, J Nattenmüller
BACKGROUND: Extranodal manifestations occur in up to 40% of non-Hodgkin lymphomas. The prevalence of extranodal involvement has increased. OBJECTIVES: A comprehensive overview on lymphoma involvement in the parenchymatous abdominal organs, the gastrointestinal tract, and the peritoneal cavity under due consideration of clinical implications is given. MATERIALS AND METHODS: A selective literature search with analysis of dedicated original research articles and reviews was carried out...
December 8, 2017: Der Radiologe
https://www.readbyqxmd.com/read/29222570/narrative-language-sampling-in-typical-development-implications-for-clinical-trials
#3
Marie Moore Channell, Susan J Loveall, Frances A Conners, Danielle J Harvey, Leonard Abbeduto
Purpose: This study examined cross-sectional age-related trajectories of expressive language variables (syntactic complexity, lexical diversity, unintelligibility, dysfluency, and talkativeness) derived from a narrative language sampling procedure. Method: Narrative samples were analyzed from 103 typically developing individuals, ages 4-21 years. Results: Results showed that this procedure was effective for the entire age range, with participants producing an utterance on virtually every page of the wordless picture books used to prompt the narrative...
December 7, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29222266/impact-of-bone-disease-and-pain-in-thalassemia
#4
REVIEW
Antonio Piga
Conventional treatment of thalassemia, namely regular blood transfusion and iron chelation, improves perspectives and quality of life; however, successful treatment leads to more time in which long-term complications such as bone disease can develop. Thalassemia bone disease (TBD) is unique: all aspects, from bone anatomy and bone quality to mineral density, may be affected, with important morbidity including osteoporosis, fractures, spinal deformities, nerve compression, and pain. Clinical presentations include growth impairment, rickets-like features, back pain, spinal deformities, any sign of nerve compression, severe osteoporosis, and fragility fractures...
December 8, 2017: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/29222249/thrombocytopenia-in-pregnancy
#5
REVIEW
Douglas B Cines, Lisa D Levine
Thrombocytopenia develops in 5% to 10% of women during pregnancy or in the immediate postpartum period. A low platelet count is often an incidental feature, but it might also provide a biomarker of a coexisting systemic or gestational disorder and a potential reason for a maternal intervention or treatment that might pose harm to the fetus. This chapter reflects our approach to these issues with an emphasis on advances made over the past 5 to 10 years in understanding and managing the more common causes of thrombocytopenia in pregnancy...
December 8, 2017: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/29222221/acute-pancreatitis-following-oesophagogastroduodenoscopy
#6
Nnamdi Arinze Nwafo
Acute pancreatitis is a well-recognised complication of endoscopic procedures like endoscopic retrograde cholangiopancreatography but not oesophagogastroduodenoscopy (OGD). I report a case of a 33-year-old woman, admitted with severe epigastric pain and vomiting 2 hours after an elective OGD for evaluation of chronic gastrointestinal symptoms. Pancreatitis was diagnosed on the basis of elevated lipase (40 790 U/L; normal 11-82) and findings on imaging studies. Other common causes of acute pancreatitis such as gallstones, alcohol and medications were ruled out...
December 7, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29222033/multiple-perspectives-of-qingkailing-injection-fraction-single-compound-in-revealing-the-hepatotoxicity-of-baicalin-and-hyodeoxycholic-acid
#7
Jiayu Zhang, Shifeng Wang, Lulu Xu, Qiao Zhang, Zhanpeng Shang, Yanling Zhang, Qinghua Wu, Shiyou Li, Yanjiang Qiao
ETHNOPHARMACOLOGICAL RELEVANCE: The complexity of ingredients in traditional Chinese medical formulas and the limited consideration of toxicological responses are fundamental issues that hamper prognostic information of drug quality control. MATERIALS AND METHODS: A multidisciplinary approach for quality control of Qingkailing injection (QKL) regarding drug induced liver toxicity was described for the first time. High content image analysis (HCA) was combined with reverse-phase chromatographic separation and high-resolution MS detection technologies to provide the dynamic responses of HepG2 cell injury...
December 5, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29221912/variable-clinical-phenotype-in-two-siblings-with-aicardi-gouti%C3%A3-res-syndrome-type-6-and-a-novel-mutation-in-the-adar-gene
#8
Lisa Schmelzer, Martin Smitka, Christine Wolf, Nadja Lucas, Victoria Tüngler, Gabriele Hahn, Andreas Tzschach, Nataliya Di Donato, Min Ae Lee-Kirsch, Maja von der Hagen
Aicardi-Goutières syndrome (AGS) is a hereditary inflammatory encephalopathy resulting in severe neurological damage in the majority of cases. We report on two siblings with AGS6 due to compound heterozygosity for a known and a novel mutation in the ADAR gene and a strikingly variable phenotype. The first sibling presented at 12 months of age with a subacute encephalopathy following a mild respiratory infection. The child developed a spastic tetraparesis, generalized dystonia and dysarthria. In contrast, the younger sibling presented with an acute episode of neurological impairment in his third year of life, from which he recovered without sequelae within a few weeks...
November 22, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/29221457/capillaria-hepatica-calodium-hepaticum-infection-in-a-horse-a-case-report
#9
Akihiro Ochi, Tatsuro Hifumi, Takanori Ueno, Yoshinari Katayama
BACKGROUND: Capillaria hepatica is a zoonotic parasite in humans and animals and has a worldwide distribution. However, infections in mammals apart from rodents, which are natural hosts of the parasite, have rarely been reported. This report describes the first known case of C. hepatica infection in a horse in Japan. CASE PRESENTATION: A 3-year-old filly without clinical signs was presented at a slaughterhouse in Japan. Gross examination revealed white to tan nodules 0...
December 8, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29221350/glomus-tumors-of-the-trachea-2-case-reports-and-a-review-of-the-literature
#10
Chun Wang, Yuan Ma, Xin Zhao, Pei-Li Sun, Ying-Ming Zhang, Mao Huang, Yan Zhu, Shu-Xian Jin
Glomus tumors (GTs) of the trachea are very rare neoplasms that usually arise from the distal portion of the respiratory tree. The origin of these tumors is modified smooth muscle cells of glomus bodies. In this study, we describe two cases of GT of the trachea, as well as the histologic features of these tumors and their treatments. One tumor was diagnosed via bronchoscopic biopsy, and the other tumor was diagnosed via surgery. Clinical follow-up showed that the two patients are alive and well after 8 and 15 months post-treatment, respectively...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221317/cystic-tumor-of-the-atrioventricular-node-a-review-of-the-literature
#11
REVIEW
Jessica G Y Luc, Kevin Phan, Vakhtang Tchantchaleishvili
Primary cardiac tumors are uncommon clinical entities with an incidence of 0.0017% to 0.03% of all autopsies. Cystic tumor of the atrioventricular (AV) node, also known as mesothelioma of the AV node, is a benign congenital tumor that is located in the triangle of Koch in the AV nodal region of the atrial septum of the heart. It comprises of 2.7% of cardiac tumors and is the most common primary cardiac tumor causing sudden death. We herein review the etiology, presentation, differential diagnosis, diagnosis, management, surgical approaches and outcomes of this rare tumor...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221314/thoracoscopic-left-s4a-subsegmentectomy
#12
Akira Hamada, Hiroyuki Oizumi, Hirohisa Kato, Jun Suzuki, Hikaru Watarai, Katsuyuki Suzuki, Takanori Sasage, Mitsuaki Sadahiro
A 63-year-old woman who underwent a left hepatic lobectomy for hilar cholangiocarcinoma was referred to our department for further management. Chest computed tomography showed a lung nodule that was increased in size to 8 mm in the S4a. The differential diagnosis was metastasis versus primary lung cancer. Thoracoscopic left S4a subsegmentectomy was performed. The operative time was 158 min. The blood loss was minimal. Air leakage was not observed, and a chest tube was removed on POD 1. The patient was discharged home on POD 3...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221294/using-m-mode-ultrasonography-to-assess-diaphragm-dysfunction-and-predict-the-success-of-mechanical-ventilation-weaning-in-elderly-patients
#13
Daozheng Huang, Huan Ma, Wenzhao Zhong, Xiaoting Wang, Yan Wu, Tiehe Qin, Shouhong Wang, Ning Tan
Background: Ultrasonography (US) is a non-invasive and commonly available bedside diagnostic tool. The aim of this study was to assess the utility of M-mode US on ventilator weaning outcomes in elderly patients. Methods: This was a single center, prospective, observational study in patients aged 80 years or older who were in the medical intensive care unit, had undergone mechanical ventilation for >48 hours, and met the criteria for a spontaneous breathing trial (SBT)...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221282/induction-chemoradiotherapy-using-docetaxel-and-cisplatin-with-definitive-dose-radiation-followed-by-surgery-for-locally-advanced-non-small-cell-lung-cancer
#14
Hidejiro Torigoe, Junichi Soh, Shuta Tomida, Kei Namba, Hiroki Sato, Kuniaki Katsui, Katsuyuki Hotta, Kazuhiko Shien, Hiromasa Yamamoto, Masaomi Yamane, Susumu Kanazawa, Katsuyuki Kiura, Shinichiro Miyoshi, Shinichi Toyooka
Background: Induction chemoradiotherapy (CRT) followed by surgery is a therapeutic option for locally advanced non-small cell lung cancer (LA-NSCLC). Typically, around 40-50 Gy of radiation is applied as the induction-dose; however, a definitive-dose (DD) of radiation (60 Gy or higher) is occasionally applied to increase local control. We investigated the impact of induction CRT with DD radiation in LA-NSCLC patients treated with a single regimen of docetaxel and cisplatin. Methods: We reviewed 110 patients with LA-NSCLC who underwent induction CRT followed by surgery using a single regimen (docetaxel and cisplatin) between January 1999 and December 2014 at our hospital...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221270/analysis-of-the-clinical-differentiation-of-pulmonary-sclerosing-pneumocytoma-and-lung-cancer
#15
Jun Zhu
Background: Pulmonary sclerosing pneumocytoma (PSP) is a rare benign lung tumor. This study investigated the diagnostic experience of PSP and lung cancer. Methods: This study is a retrospective study. We observed the locations of lung lesions, imaging form and clinical symptoms, and recorded the surgical complications through comparing patients with PSP and lung cancer. Results: From December 2012 to February 2017, 187 PSP cases and 197 lung cancer cases were collected...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221063/200-gb-s-transmission-using-a-dual-polarization-o-band-silicon-photonic-intensity-modulator-for-stokes-vector-direct-detection-applications
#16
Eslam El-Fiky, Mohamed Osman, Mohammed Sowailem, Alireza Samani, David Patel, Rui Li, Md G Saber, Yun Wang, Nicolas Abadia, Yannick D'Mello, David V Plant
We present a dual-polarization O-band silicon photonic (SiP) transmitter for intra-datacenter optical interconnects. The transmitter is built using two identical O-band traveling wave Mach-Zehnder modulators with an average VπL and a bandwidth at 1.5 V bias voltage of 2.88 V.cm and 24.5 GHz, respectively. We experimentally demonstrate the transmitter in a Stokes vector direct-detection (SV-DD) system for dual-polarization intensity modulated signals with 2-level and 4-level pulse amplitude modulation (DP-PAM2 and DP-PAM4) formats...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29219900/diagnostic-challenges-in-nocardia-keratitis
#17
Joséphine Behaegel, Sorcha Ní Dhubhghaill, Carina Koppen
OBJECTIVE: To present a case of diagnostic confusion in Nocardia keratitis in a contact lens wearer and to illustrate the characteristic clinical findings of this rare entity. METHODS: Case report of Nocardia keratitis that was mistaken for acanthamoeba, herpetic, and fungal keratitis in three tertiary corneal referral centers before the correct diagnosis of Nocardia infection was made. RESULTS: A 29-year-old contact lens wearer was referred to our hospital for a contact lens-associated bacterial keratitis, not improving under standard bacterial treatment...
December 5, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/29219891/thrombotic-thrombocytopenic-purpura-in-a-child-treated-for-acute-lymphoblastic-leukemia-case-report-and-review-of-literature
#18
Francesco De Leonardis, Roberta Koronica, Rosa Maria Daniele, Nicola Santoro
Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy caused by deficiency of von Willebrand factor-cleaving protease ADAMTS13. Large von Willebrand multimer formation and intravascular platelet aggregation affecting the arterioles and capillaries can result in death unless early treatment is administered. We report on the case of a child with TTP associated with a human herpes virus type-6 infection occurring during chemotherapy for acute lymphoblastic leukemia who was effectively treated by fresh frozen plasma infusions and antiviral therapy...
December 6, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29218797/lymphoepithelioma-like-carcinoma-of-the-uterine-cervix-cytomorphologic-features-and-diagnostic-pitfalls-by-liquid-based-cytology
#19
Isaac Lloyd, Barbara Chadwick
Lymphoepithelioma-like carcinoma (LELC) is a rare variant of cervical squamous cell carcinoma with unclear HPV and EBV association. Due to the accompanying and often obscuring lymphocytic inflammation, malignant cells may be difficult to recognize on cytologic samples and can mimic several more common benign and atypical cervical lesions. In this case report, we describe the cytomorphologic findings of LELC by liquid-based cytology in a 59-year-old Caucasian woman who was positive for high risk HPV but had no visible cervical lesions...
December 8, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29218653/differential-diagnosis-of-pancreatic-epidermoid-cyst-without-a-solid-component-residual-splenic-tissue-vs-mucinous-cystic-neoplasm
#20
Kousei Ishigami, Akihiro Nishie, Hiroyuki Irie, Yoshiki Asayama, Yasuhiro Ushijima, Yukihisa Takayama, Daisule Okamoto, Nobuhiro Fujita, Takao Ohtsuka, Tetsuhide Ito, Naoki Mochidome, Hiroshi Honda
PURPOSE: The purpose of this study was to clarify whether there are differences in imaging findings between pancreatic epidermoid cyst (EDC) without a solid component (residual splenic tissue) and mucinous cystic neoplasm (MCN). MATERIALS AND METHODS: The study group consisted of histologically proven EDC (eight cases) and MCN (20 cases). CT and MRI findings were compared on the following imaging findings: the shape of the cystic lesions and the presence or absence of septum, calcification, and high-intensity fluid on T1- and diffusion-weighted images (b factor = 1000)...
December 7, 2017: Journal of Gastrointestinal Cancer
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