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Fetal echocardiography

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https://www.readbyqxmd.com/read/29306968/the-impact-of-third-trimester-genetic-counseling
#1
Reuven Sharony, Offra Engel, Shira Litz-Philipsborn, Rivka Sukenik-Halevy, Tal Biron-Shental, Mark I Evans
OBJECTIVE: To evaluate the impact of genetic counseling (GC) during the third trimester by analyzing changes in pregnancy management and the correlation with postnatal findings. METHODS: This was a retrospective study. Pregnancy course and neonatal follow-up were analyzed according to the reason for referral and implementation of recommendations. RESULTS: The records of neonates born to 181 women were retrieved. Fifty-two women (group 1-29%) qualified for pregnancy termination under Israeli guidelines and laws, and 129 (group 2-71%) were not at the time they were referred...
January 6, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29287140/introduction-from-fetal-echocardiography-to-fetal-cardiology-a-journey-of-over-half-a-century
#2
Shuping Ge, Dev Maulik
In this Special Issue of the Journal, 8 review articles that represent the new developments and applications of fetal echocardiography and fetal cardiology for diagnosis, prognosis, and treatment of fetal cardiovascular disease are included. The goal was to provide an updated review of the evidence for the current and emerging use of fetal echocardiography and cardiac magnetic resonance, improved diagnosis of challenging congenital heart disease, new tools for evaluation of fetal systolic and diastolic function, better prognosis and risk stratification of newborns with congenital heart diseases, and new and promising therapies for fetuses with cardiovascular disease...
December 2017: Echocardiography
https://www.readbyqxmd.com/read/29287138/4d-fetal-echocardiography-an-update
#3
Greggory R DeVore, Gary Satou, Mark Sklansky
With the introduction of the electronic 4-dimensional and spatial-temporal image Correlation (e-STIC), it is now possible to obtain large volume datasets of the fetal heart that are virtually free of artifact. This allows the examiner to use a number of imaging modalities when recording the volumes that include two-dimensional real time, power and color Doppler, and B-flow images. Once the volumes are obtained, manipulation of the volume dataset allows the examiner to recreate views of the fetal heart that enable examination of cardiac anatomy...
December 2017: Echocardiography
https://www.readbyqxmd.com/read/29287137/maternal-hyperoxygenation-a-potential-therapy-for-congenital-heart-disease-in-the-fetuses-a-systematic-review-of-the-current-literature
#4
Jennifer Co-Vu, Dalia Lopez-Colon, Himesh V Vyas, Natalie Weiner, Curt DeGroff
OBJECTIVES: To assess efficacy, safety, outcomes, and intrauterine complications following maternal hyperoxygenation (MH) therapy in fetuses with congenital heart disease (CHD). METHODS: A systematic review was performed following an electronic search of databases. Articles were published before January 1, 2017, in an English-language and non-English-language journals (with English translations), and included human fetuses and expectant mothers with a fetal diagnosis of CHD who received MH...
December 2017: Echocardiography
https://www.readbyqxmd.com/read/29287135/pulmonary-hypoplasia-in-fetuses-with-congenital-conotruncal-defects
#5
Qian Wang, Ying Zhao, Ling Han, Ye Zhang, Shuping Ge, Yihua He
OBJECTIVES: We sought to investigate pulmonary hypoplasia (PH) and associated risk factors in fetuses with congenital conotruncal defect (CTD). METHODS: A total of 75 fetuses with CTD (gestational age (GA): 22-32 weeks) and 150 normal GA-matched fetuses as the control group were studied. We measured diameters of aorta (Ao); main, left, and right pulmonary artery (PA); and their Z-scores by fetal echocardiography (FE). We also measured the lung area, lung area/chest area ratio (LCR), lung-to-head circumference ratio (LHR), right lung area/head circumference2 (quantitative lung index, QLI), and Z-scores...
December 2017: Echocardiography
https://www.readbyqxmd.com/read/29287134/prenatal-diagnosis-of-total-anomalous-pulmonary-venous-connection-by-2d-and-3d-fetal-echocardiography
#6
Ye Zhang, Qin Shao, Lin Sun, Shuping Ge, Yihua He
OBJECTIVE: Prenatal diagnosis of total anomalous pulmonary venous connection (TAPVC) by fetal echocardiography (FE) remains a challenge. We sought to ascertain the diagnostic accuracy of 2D and 3D spatiotemporal image correlation (STIC) FE and the potential incremental value of 3D STIC FE for prenatal diagnosis and assessment of TAPVC. METHODS: This study was conducted retrospectively in a single tertiary referral center. The study population consisted of 74 TAPVC from 17 063 fetuses by FE from August 2010 to April 2016...
December 2017: Echocardiography
https://www.readbyqxmd.com/read/29287133/cardiac-function-and-dysfunction-in-the-fetus
#7
Luke Eckersley, Lisa K Hornberger
Evaluation of fetal cardiac function is one of the most important components of fetal echocardiography. Fetal cardiac dysfunction is closely linked to risk of intrauterine fetal demise, in many, but not all cases is indicative of worse postnatal prognosis and may prompt the use of medications or interventions to optimize outcomes. There may be implications for termination versus continuation of pregnancy, an indication for early delivery, a change in location and even mode of delivery. In extreme cases, fetal cardiac dysfunction may prompt prenatal or early neonatal listing for cardiac transplantation...
December 2017: Echocardiography
https://www.readbyqxmd.com/read/29287132/fetal-echocardiography-for-planning-perinatal-and-delivery-room-care-of-neonates-with-congenital-heart-disease
#8
Laura Sanapo, Jay D Pruetz, Maciej Słodki, M Beth Goens, Anita J Moon-Grady, Mary T Donofrio
Fetal echocardiography facilitates the prenatal diagnosis of infants with congenital heart disease (CHD) and through sequential examinations, allows assessment of fetal hemodynamics and cardiovascular status from the time of diagnosis to delivery. Fetal cardiologists have created diagnostic protocols aimed at risk stratifying severity and potential postnatal compromise in fetuses with CHD, and identifying those who may require special intervention at birth or within the first days of life. In this article, we review fetal cardiovascular physiology, the progression of CHD in utero and fetal echocardiographic findings used for risk stratification of newborns with CHD, as well as some of the basic principles of planning for the neonatal resuscitation and initial transitional care of these complex newborns...
December 2017: Echocardiography
https://www.readbyqxmd.com/read/29287130/a-brief-history-of-fetal-echocardiography-and-its-impact-on-the-management-of-congenital-heart-disease
#9
Dev Maulik, Navin C Nanda, Devika Maulik, Gustavo Vilchez
Congenital heart disease (CHD), the most common congenital malformation, is associated with adverse outcome. Development of fetal echocardiography has made prenatal diagnosis of CHD a reality, and in the process revolutionized its management. This historical review briefly narrates this development over the decades focusing on the emergence of the primary modalities of fetal echocardiography comprised of the time-motion mode, two-dimensional B-mode, spectral Doppler, color Doppler, and three- and four-dimensional cardiac imaging...
December 2017: Echocardiography
https://www.readbyqxmd.com/read/29285173/rapamycin-therapy-for-neonatal-tuberous-sclerosis-complex-with-cardiac-rhabdomyomas-a-case-report-and-review
#10
Shanshan Mao, Qi Long, Huijia Lin, Jinling Liu
Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disease that varies greatly in its expression. The current study reports a novel case of TSC caused by a TSC2 mutation (TSC2c.1642_1643insA or TSC2p.K549fsX589), in which multiple cardiac rhabdomyomas were detected by fetal echocardiography in week 31 of pregnancy. The infant was delivered successfully; however, seizures began 16 days following birth. Subsequent genetic tests confirmed a diagnosis of TSC. Rapamycin treatment resulted in regression of cardiac rhabdomyomas and controlled seizures...
December 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29246511/fetal-cardiac-function-in-maternal-diabetes-a%C3%A2-conventional-and-speckle-tracking-echocardiographic-study
#11
Joana O Miranda, Rui J Cerqueira, Carla Ramalho, José Carlos Areias, Tiago Henriques-Coelho
BACKGROUND: Intrauterine exposure to a diabetic environment is associated with adverse fetal myocardial remodeling. The aim of this study was to assess the biventricular systolic and diastolic function of fetuses exposed to maternal diabetes (MD) compared with control subjects, using a comprehensive cardiac functional assessment and exploring the role of speckle-tracking to assess myocardial deformation. The authors hypothesized that fetuses exposed to MD present signs of biventricular dysfunction, which can be detected by deformation analysis...
December 12, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29245172/comment-on-how-fetal-growth-restriction-and-preterm-birth-affects-cardiac-morphology-and-function-during-infancy
#12
P P Bassareo, G Mercuro
We read with great interest the recent paper by Cohen et al regarding the early morphological and functional changes induced by intrauterine growth restriction on the heart and detected during echocardiography(1). In particular, the authors found increases in left ventricular sphericity and posterior and relative wall thicknesses. They also noted that the diastolic function, measured with tissue Doppler imaging, dropped. This article is protected by copyright. All rights reserved.
December 15, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29221765/advances-in-fetal-echocardiography
#13
REVIEW
Helena M Gardiner
The development of fetal echocardiography and success in prenatal cardiac screening programs over the past 30 years has been driven by technical innovation and influenced by the different approaches of the various specialties practicing it. Screening for congenital heart defects no longer focuses on examining a limited number of pregnant women thought to be at increased risk, but instead forms an integrated part of a high-quality anatomical ultrasound performed in the second trimester using the 'five-transverse view' protocol...
December 5, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29216197/shift-toward-greater-pathologic-post-myocardial-infarction-remodeling-with-loss-of-the-adaptive-hypertrophic-signaling-of-alpha1-adrenergic-receptors-in-mice
#14
Che-Chung Yeh, Yanying Fan, Yanchun Xu, Yi-Lin Yang, Paul C Simpson, Michael J Mann
RATIONALE: We have hypothesized that post-infarction cardiac remodeling can be influenced by shifts in the balance between intracellular mediators of "pathologic" and "physiologic" hypertrophy. Although alpha1 adrenergic receptors (alpha1-ARs) mediate pro-adaptive hypertrophy during pressure overload, little is known about their role or downstream mediators after myocardial infarction. METHODS: We performed loss-of-function experiments via coronary ligation in alpha1A-AR knockout (AKO) mice...
2017: PloS One
https://www.readbyqxmd.com/read/29201331/determination-of-fetal-left-ventricular-volume-based-on-two-dimensional-echocardiography
#15
Li Yu, Yi Guo, Yuanyuan Wang, Jinhua Yu, Ping Chen
Determination of fetal left ventricular (LV) volume in two-dimensional echocardiography (2DE) is significantly important for quantitative analysis of fetal cardiac function. A backpropagation (BP) neural network method is proposed to predict LV volume more accurately and effectively. The 2DE LV border and volume are considered as the input and output of BP neural network correspondingly. To unify and simplify the input of the BP neural network, 16 distances calculated from the border to its center with equal angle are used instead of the border...
2017: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29190628/cord-blood-biomarkers-of-cardiac-dysfunction-and-damage-in-term-growth-restricted-fetuses-classified-by-severity-criteria
#16
Míriam Perez-Cruz, Fàtima Crispi, María Teresa Fernández, Johanna Alexandra Parra, Anna Valls, María Dolores Gomez Roig, Eduard Gratacós
OBJECTIVE: To assess cardiovascular function and damage in term small-for-gestational-age (SGA) and intrauterine growth-restricted (IUGR) fetuses by echocardiography and biomarkers in cord blood. METHODS: This was a cohort study including 60 normal fetuses and 47 term small fetuses subclassified as small for gestational age (SGA) with estimated fetal weight (EFW) between the 3rd and 9th centiles and normal fetoplacental Doppler (n = 14) or intrauterine growth restriction (IUGR, n = 33) if EFW <3rd centile or EFW <10th centile together with cerebroplacental ratio <5th and/or mean uterine artery pulsatility index >95th centile...
November 30, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/29170884/is-retrograde-blood-flow-of-aortic-isthmus-useful-for-the-prenatal-screening-of-coarctation-of-the-aorta-by-fetal-color-doppler-echocardiography-a-preliminary-study
#17
Hiroshi Kawamura, Noboru Inamura, Yuka Inoue, Yukiko Kawazu, Futoshi Kayatani, Nobuaki Mitsuda
PURPOSE: To validate the relationship between retrograde blood flow in the aortic isthmus (AoI-R) by color Doppler in fetal echocardiography and postnatal coarctation of the aorta (CoA) diagnosed as isthmus narrowing. METHODS: This was a retrospective study of 22 cases of prenatally suspected simple CoA or CoA with small ventricular septum defect based on fetal echocardiography performed by pediatric cardiologists in our hospital. Gestational age at the first detection of AoI-R and the optimal cut-off value for the prediction of postnatal CoA were mainly evaluated according to the postnatal diagnosis of CoA...
November 23, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/29166810/anesthetic-management-of-amniotic-fluid-embolism-a-multi-center-retrospective-cohort-study
#18
Shiri Skolnik, Alexander Ioscovich, Leonid A Eidelman, Atara Davis, Anat Shmueli, Amir Aviram, Sharon Orbach-Zinger
INTRODUCTION: Amniotic fluid embolism (AFE) is a rare and potentially lethal obstetric complication, commonly occurring during labor, delivery, or immediately postpartum. There is a paucity of data regarding incidence, risk factors, and clinical management. Our primary objective in this study was to evaluate clinical presentation of AFE and delineate anesthesia management of these cases. METHODS: This 10 years retrospective multi-center cohort study was performed in five tertiary university-affiliated medical centers, between the years 2005 and 2015...
November 22, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29116459/neonatal-systemic-lupus-erythematosus-syndrome-a-comprehensive-review
#19
REVIEW
Federica Vanoni, Sebastiano A G Lava, Emilio F Fossali, Riccardo Cavalli, Giacomo D Simonetti, Mario G Bianchetti, Marie-Ange Bozzini, Carlo Agostoni, Gregorio P Milani
Neonatal lupus erythematosus is an uncommon syndrome, which is caused by transplacental passage of maternal autoantibodies to Sjögren's syndrome A or B autoantigens. The clinical presentation includes distinctive cutaneous lesions resembling those seen in systemic lupus erythematosus, hepatobiliary disease, and cytopenias, which disappear with the clearance of maternal autoantibodies. The most severe presentation is a total atrioventricular heart block, which begins during the second trimester of gestation and is irreversible...
December 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29115693/effects-of-fetal-growth-restriction-and-preterm-birth-on-cardiac-morphology-and-function-during-infancy
#20
Emily Cohen, Christie Whatley, Flora Y Wong, Euan M Wallace, Joanne C Mockler, Alexsandria Odoi, Samantha Hollis, Rosemary S C Horne, Stephanie R Yiallourou
AIM: To investigate the effects of fetal growth restriction (FGR) and prematurity on cardiac morphology and function in infancy. We hypothesized that FGR and prematurity would both alter cardiac development. METHODS: Cardiac morphology and function were evaluated in 24 preterm FGR infants (p-FGR) and 23 preterm and 19 term appropriately-grown-for-gestational-age infants (p-AGA and t-AGA, respectively) by conventional echocardiography and Tissue Doppler Imaging. p-FGR and p-AGA infants were studied on postnatal Day One and all groups were studied at one and six months post-term age...
November 8, 2017: Acta Paediatrica
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