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https://www.readbyqxmd.com/read/28538396/effects-of-teriparatide-versus-alendronate-for-treatment-of-postmenopausal-osteoporosis-a-meta-analysis-of-randomized-controlled-trials
#1
Ya-Kang Wang, Si-Qing Qin, Tao Ma, Wei Song, Ren-Qi Jiang, Jian-Bin Guo, Kun Li, Yu-Min Zhang
OBJECTIVES: Osteoporosis remains a clinical challenge. Teriparatide is an anabolic drug and alendronate is an antiresorptive agent; both are used in the treatment of osteoporosis. Comprehensive reviews investigating the comparative safety and efficacy of teriparatide versus alendronate are scarce. Therefore, we conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the safety and efficacy of teriparatide versus alendronate for the treatment of postmenopausal osteoporosis...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28473095/acr-appropriateness-criteria-%C3%A2-chronic-back%C3%A2-pain%C3%A2-suspected-sacroiliitis-spondyloarthropathy
#2
Stephanie A Bernard, Mark J Kransdorf, Francesca D Beaman, Ronald S Adler, Behrang Amini, Marc Appel, Erin Arnold, R Carter Cassidy, Bennett S Greenspan, Kenneth S Lee, Michael J Tuite, Eric A Walker, Robert J Ward, Daniel E Wessell, Barbara N Weissman
Inflammatory sacroiliitis or the seronegative axial spondyloarthropathies often presents as back pain or sacroiliac joint pain of more than 3-month duration with inflammatory symptoms and typically in patients younger than 45 years of age. Imaging plays an important role in diagnosis and disease monitoring. This article addresses the appropriate sequence of initial imaging for evaluation of a suspected spondyloarthropathy, the imaging follow-up of treatment response and the special considerations for imaging of trauma in patients with ankylosis of the spine...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28473089/acr-appropriateness-criteria-%C3%A2-suspected-osteomyelitis-septic-arthritis-or-soft-tissue-infection-excluding-spine-and-diabetic-foot
#3
Francesca D Beaman, Paul F von Herrmann, Mark J Kransdorf, Ronald S Adler, Behrang Amini, Marc Appel, Erin Arnold, Stephanie A Bernard, Bennett S Greenspan, Kenneth S Lee, Michael J Tuite, Eric A Walker, Robert J Ward, Daniel E Wessell, Barbara N Weissman
Infection of the musculoskeletal system is a common clinical problem. Differentiating soft tissue from osseous infection often determines the appropriate clinical therapeutic course. Radiographs are the recommend initial imaging examination, and although often not diagnostic in acute osteomyelitis, can provide anatomic evaluation and alternative diagnoses influencing subsequent imaging selection and interpretation. MRI with contrast is the examination of choice for the evaluation of suspected osteomyelitis, and MRI, CT, and ultrasound can all be useful in the diagnosis of soft tissue infection...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28473078/acr-appropriateness-criteria-%C3%A2-plexopathy
#4
Julie Bykowski, Joseph M Aulino, Kevin L Berger, R Carter Cassidy, Asim F Choudhri, A Tuba Kendi, Claudia F E Kirsch, Michael D Luttrull, Aseem Sharma, Vilaas S Shetty, Khoi Than, Christopher J Winfree, Rebecca S Cornelius
MRI without and with contrast is the most accurate imaging method to determine whether a process is intrinsic or extrinsic to a nerve of the brachial or lumbosacral plexus. However, there are no Current Procedural Terminology codes to correspond to imaging studies of the brachial or lumbar plexus discretely. This assessment uses "MRI of the brachial plexus" or "MRI of the lumbosacral plexus" as independent entities given that imaging acquisition for the respective plexus differs in sequences and planes compared with those of a routine neck, chest, spine, or pelvic MRI, yet acknowledges the potential variability of ordering practices across institutions...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28473075/acr-appropriateness-criteria-%C3%A2-osteoporosis%C3%A2-and%C3%A2-bone-mineral-density
#5
Robert J Ward, Catherine C Roberts, Jenny T Bencardino, Erin Arnold, Steven J Baccei, R Carter Cassidy, Eric Y Chang, Michael G Fox, Bennett S Greenspan, Soterios Gyftopoulos, Mary G Hochman, Douglas N Mintz, Joel S Newman, Charles Reitman, Zehava S Rosenberg, Nehal A Shah, Kirstin M Small, Barbara N Weissman
Osteoporosis is a considerable public health risk, with 50% of women and 20% of men >50 years of age experiencing fracture, with mortality rates of 20% within the first year. Dual x-ray absorptiometry (DXA) is the primary diagnostic modality by which to screen women >65 years of age and men >70 years of age for osteoporosis. In postmenopausal women <65 years of age with additional risk factors for fracture, DXA is recommended. Some patients with bone mineral density above the threshold for treatment may qualify for treatment on the basis of vertebral body fractures detected through a vertebral fracture assessment scan, a lateral spine equivalent generated from a commercial DXA machine...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28473069/acr-appropriateness-criteria-%C3%A2-back-pain-child
#6
Timothy N Booth, Ramesh S Iyer, Richard A Falcone, Laura L Hayes, Jeremy Y Jones, Nadja Kadom, Abhaya V Kulkarni, John S Myseros, Sonia Partap, Charles Reitman, Richard L Robertson, Maura E Ryan, Gaurav Saigal, Bruno P Soares, Aylin Tekes-Brady, Andrew T Trout, Nicholas A Zumberge, Brian D Coley, Susan Palasis
It is now generally accepted that nontraumatic back pain in the pediatric population is common. The presence of isolated back pain in a child has previously been an indication for imaging; however, recently a more conservative approach has been suggested using clinical criteria. The presence of constant pain, night pain, and radicular pain, alone or in combination, lasting for 4 weeks or more, constitute clinical red flags that should prompt further imaging. Without these clinical red flags, imaging is likely not indicated...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28456674/bone-morphogenetic-protein-use-in-spine-surgery-in-the-united-states-how-have-we-responded-to-the-warnings
#7
Javier Z Guzman, Robert K Merrill, Jun S Kim, Samuel C Overley, James E Dowdell, Sulaiman Somani, Andrew C Hecht, Samuel K Cho, Sheeraz A Qureshi
BACKGROUND CONTEXT: Recombinant human bone morphogenetic protein-2 (rhBMP-2) has been widely adopted as a fusion adjunct in spine surgery since its approval in 2002. A number of concerns regarding adverse effects and potentially devastating complications of rhBMP-2 use led to an FDA advisory issued in 2008 cautioning its use, and a separate warning about its potential complications was published by The Spine Journal in 2011. PURPOSE: To compare trends of rhBMP-2 use in spine surgery after the FDA advisory in 2008 and The Spine Journal warning in 2011...
April 26, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28426855/journal-club-outpatient-cervical-and-lumbar-spine-surgery-is-feasible-and-safe-a-consecutive-single-center-series-of-1449-patients-erratum
#8
(no author information available yet)
No abstract text is available yet for this article.
December 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28373141/spine-hip-relations-add-understandings-to-the-pathophysiology-of-femoro-acetabular-impingement-a-systematic-review
#9
REVIEW
C Rivière, A Hardijzer, J-Y Lazennec, P Beaulé, S Muirhead-Allwood, J Cobb
Relationship between hip pathoanatomy and symptomatic FAI has been reported to be weak. This is explained by the reciprocal interaction between proximal femur and acetabular anatomies, but potentially also by the individual spine-hip relations (SHR). The key-answer for a complete understanding of the pathophysiology of FAI might lie in the comprehension of the SHRs, which have not yet been fully addressed. Therefore we conducted a systematic review to answer the subsequent questions: Is there any evidence of a relationship between FAI and (1) sagittal pelvic kinematics, (2) pelvic incidence, and (3) types of SHRs? A systematic review of the existing literature utilizing PubMed and Google search engines was performed in December 2016...
April 1, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28373138/the-influence-of-spine-hip-relations-on-total-hip-replacement-a-systematic-review
#10
REVIEW
C Rivière, J-Y Lazennec, C Van Der Straeten, E Auvinet, J Cobb, S Muirhead-Allwood
Sagittal pelvic kinematics along with spino-pelvic angular parameters have recently been studied by numerous investigators for their effect on total hip replacement (THR) clinical outcomes, but many issue of spine-hip relations (SHR) are currently unexplored. Therefore, our review aims at clarifying the following questions: is there any evidence of a relationship between articular impingement/dislocation risk in primary THR and (1) certain sagittal pelvic kinematics patterns, (2) pelvic incidence, and (3) types of SHRs? A systematic review of the existing literature utilising PubMed and Google search engines was performed in January 2017...
April 1, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28347680/top-50-most-cited-articles-on-primary-tumors-of-the-spine
#11
REVIEW
Nima Alan, Jonathan Cohen, Alp Ozpinar, Nitin Agarwal, Adam S Kanter, David O Okonkwo, D Kojo Hamilton
Citation analysis was performed in order to identify the top 50 most cited articles pertaining to the field of primary spinal tumors. This collection of articles highlights important trends in the neurosurgical literature. We searched the Thomson Reuters Web of Knowledge in order to identify articles pertaining to primary tumors of the spine. Impertinent articles were removed. The top 50 most cited articles were identified. Thereafter, article characteristics were determined including article type, article topic, level of evidence, and citation rate...
March 24, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28341955/osteoplasty-in-crooked-nose-deformity-a-novel-approach
#12
Ilker Koçak, Erol Senturk
BACKGROUND: Crooked nose deformity is one of the most difficult issues to correct by rhinoplasty, as it can result in undesired late sequelae. Revision rates are often high, and numerous operational techniques have been tested. This study describes a crooked nose rhinoplasty technique that reduces the need for a double osteotomy in the long nasal bone. METHODS: This study included 26 patients with an I-shaped crooked nose deformity. In the surgical correction of the crooked nose deformity, previously defined techniques were applied to the cartilage identically...
March 24, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28331220/identification-of-biallelic-extl3-mutations-in-a-novel-type-of-spondylo-epi-metaphyseal-dysplasia
#13
Long Guo, Nursel H Elcioglu, Shuji Mizumoto, Zheng Wang, Bilge Noyan, Hatice M Albayrak, Shuhei Yamada, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura, Shiro Ikegawa
Spondylo-epi-metaphyseal dysplasia (SEMD) is a group of inherited skeletal diseases characterized by the anomalies in spine, epiphyses and metaphyses. SEMD is highly heterogeneous and >20 distinct entities have been identified. Here we describe a novel type of SEMD in two unrelated Turkish patients who presented with severe platyspondyly, kyphoscoliosis, pelvic distortion, constriction of the proximal femora and brachydactyly. Although these phenotypes overlap considerably with some known SEMDs, they had a novel causal gene, exostosin-like glycosyltransferase 3 (EXTL3), that encodes a glycosyltransferase involved in the synthesis of heparin and heparan sulfate...
March 23, 2017: Journal of Human Genetics
https://www.readbyqxmd.com/read/28294069/wallet-neuritis-an-example-of-peripheral-sensitization
#14
Md Abu Bakar Siddiq, Israt Jahan, Sam Masihuzzaman
BACKGROUND: Wallet neuritis is an example of extra-spinal tunnel neuropathy concerning sciatic nerve. Its clinical appearance often gets confused with sciatica of lumbar spine origin. Wallet-induced chronic sciatic nerve constriction produces gluteal and ipsilateral lower extremity pain, tingling, and burning sensation. It was Lutz, first describing credit-card wallet sciatica in an Attorney, surfaced on Journal of American Medical Association (JAMA), 1978; however, the condition has not been well-studied in various other occupations...
March 9, 2017: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28245207/100-most-influential-publications-in-scoliosis-surgery
#15
James Jun Zhou, Michael T Koltz, Nitin Agarwal, Zachary J Tempel, Adam S Kanter, David O Okonkwo, D Kojo Hamilton
STUDY DESIGN: Bibliometric analysis. OBJECTIVE: To apply the established technique of citation analysis to identify the 100 most influential articles in scoliosis surgery research published between 1900 and 2015. SUMMARY OF BACKGROUND DATA: Previous studies have applied the technique of citation analysis to other areas of study. This is the first article to apply this technique to the field of scoliosis surgery. METHODS: A two-step search of the Thomson Reuters Web of Science was conducted to identify all articles relevant to the field of scoliosis surgery...
March 2017: Spine
https://www.readbyqxmd.com/read/28215603/a-new-concept-for-an-old-pain-carpalgia-pain-in-the-wrist
#16
L Maizo Alemán
OBJECTIVE: The idea of this article is to propose to the general use of a new term to semiologically describe musculoskeletal wrist pain. FINDINGS: The use of terms with Greco-Latin roots is common in the medical field. The result is expressed in the newly coined word (neologism) "carpalgia", defined as musculoskeletal pain in the region of the wrist. CONCLUSIONS: The use of other terms related to musculoskeletal pain of the shoulder (omalgia), knee (gonalgia), metatarsus (metatarsalgia), spine (cervicalgia, lumbalgia), or hip (coxalgia) terms have demonstrated their importance through their applicability in different medical journals in recent years...
February 15, 2017: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/28186942/use-of-combination-therapy-in-the-treatment-of-primary-osteoporosis-protocol-for-a-network-meta-analysis-of-randomised-trials
#17
Shenghan Lou, Houchen Lv, Yuxiang Chen, Licheng Zhang, Peifu Tang
INTRODUCTION: The existing medications approved for treatment of primary osteoporosis can be divided into antiresorptive drugs and anabolic drugs. According to the mechanisms of action, the combined therapy may produce a synergistic effect on bone mineral density (BMD) compared with monotherapy, and thus improves the efficacy of fracture resistance. This network meta-analysis aims to compare the efficacies of different combined methods for the treatment of primary osteoporosis. METHODS AND ANALYSIS: MEDLINE, EMBASE and Cochrane databases will be searched to identify all randomised controlled trials (RCTs) and quasi-RCTs that evaluate the effectiveness of combined therapy versus monotherapy for primary osteoporosis...
November 8, 2016: BMJ Open
https://www.readbyqxmd.com/read/28125523/machine-learning-based-classification-of-38-years-of-spine-related-literature-into-100-research-topics
#18
David C Sing, Lionel N Metz, Stefan Dudli
STUDY DESIGN: Retrospective review. OBJECTIVE: To identify the top 100 spine research topics. SUMMARY OF BACKGROUND DATA: Recent advances in "machine learning," or computers learning without explicit instructions, have yielded broad technological advances. Topic modeling algorithms can be applied to large volumes of text to discover quantifiable themes and trends. METHODS: Abstracts were extracted from the National Library of Medicine PubMed database from five prominent peer-reviewed spine journals (European Spine Journal [ESJ], The Spine Journal [SpineJ], Spine, Journal of Spinal Disorders and Techniques [JSDT], Journal of Neurosurgery: Spine [JNS])...
June 1, 2017: Spine
https://www.readbyqxmd.com/read/28125099/a-comparison-of-standard-two-dimensional-ultrasound-to-three-dimensional-volume-sonography-for-routine-second-trimester-fetal-imaging
#19
M E Roy-Lacroix, F Moretti, Z M Ferraro, L Brosseau, J Clancy, K Fung-Kee-Fung
OBJECTIVE: In comparison with standard two-dimensional (2D) imaging of fetal structure and biometry, we aimed to evaluate the role of three-dimensional (3D) imaging as a screening tool in the mid-trimester. STUDY DESIGN: Pregnant women presenting between 18and 22 weeks for routine anatomical survey and biometric measurements were recruited. Six volumes of fetal anatomic regions were obtained and archived for later reconstruction, along with three volumes of extra-fetal structures (placenta, cervix, amniotic fluid)...
April 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28098744/trabecular-microstructure-and-damage-affect-cement-leakage-from-the-basivertebral-foramen-during-vertebral-augmentation
#20
Shengyun Li, Chongyan Wang, Zhi Shan, Junhui Liu, Tianming Yu, Xuyang Zhang, Shunwu Fan, Blaine A Christiansen, Wenyuan Ding, Fengdong Zhao
STUDY DESIGN: A prospective study on cadaver specimens. OBJECTIVE: To explore why cement leakage from BF easily occurs during vertebral augmentation procedures. SUMMARY OF BACKGROUND DATA: Type B (through BF, basivertebral foramen) cement leakage is the most common type after vertebral augmentation, but the mechanism of this is still controversial. The contribution of vertebral trabecular bone orientation and trabecular damage during compression fracture to cement leakage is still unknown...
January 16, 2017: Spine
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