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acute coronary syndrome with ST segment elevation

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https://www.readbyqxmd.com/read/29138181/one-year-outcome-of-intensive-insulin-therapy-combined-to-glucose-insulin-potassium-in-acute-coronary-syndrome-a-randomized-controlled-study
#1
Wahid Bouida, Kaouthar Beltaief, Mohamed Amine Msolli, Nasri Bzeouich, Adel Sekma, Malek Echeikh, Malek Mzali, Hamdi Boubaker, Mohamed Habib Grissa, Riadh Boukef, Mohsen Hassine, Zohra Dridi, Asma Belguith, Fadhel Najjar, Ines Khochtali, Semir Nouira
BACKGROUND: A number of factors may offset the cardioprotective effects of glucose-insulin-potassium (GIK) on outcome of patients with acute coronary syndrome, such as hyperglycemia induced by this cocktail infusion. We performed a study to evaluate the effect of intensive insulin therapy in association with GIK on 1-year outcome in patients hospitalized for acute coronary syndrome. METHODS AND RESULTS: In a randomized prospective controlled trial we included 772 patients with non-ST-segment elevation acute coronary syndrome...
November 14, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29129350/evaluation-of-ecg-algorithms-designed-to-improve-detect-of-transient-myocardial-ischemia-to-minimize-false-alarms-in-patients-with-suspected-acute-coronary-syndrome
#2
Michele M Pelter, Yuan Xu, Richard Fidler, Ran Xiao, David W Mortara, Hu Xiao
BACKGROUND: Patients hospitalized for suspected acute coronary syndrome (ACS) are at risk for transient myocardial ischemia. During the "rule-out" phase, continuous ECG ST-segment monitoring can identify transient myocardial ischemia, even when asymptomatic. However, current ST-segment monitoring software is vastly underutilized due to false positive alarms, with resultant alarm fatigue. Current ST algorithms may contribute to alarm fatigue because; (1) they are not designed with a delay (minutes), rather alarm to brief spikes (i...
October 24, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29117666/prognostic-significance-of-non-chest-pain-symptoms-in-patients-with-non-st-segment-elevation-myocardial-infarction
#3
Inna Kim, Min Chul Kim, Keun Ho Park, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Myung Ho Jeong, Jeong Gwan Cho, Jong Chun Park, Myeong Chan Cho, Jong Jin Kim, Young Jo Kim, Youngkeun Ahn
Background/Aims: Chest pain is an essential symptom in the diagnosis of acute coronary syndrome (ACS). One-third of patients with ACS present atypically, which can influence their receiving timely lifesaving therapy. Methods: A total of 617 NSTEMI patients from the Korea Acute MI Registry (KAMIR) and the Korea Working Group on MI (KorMI) databases were analyzed. The study population was divided into two groups by symptoms at presentation (typical symptoms group, 128; atypical symptoms groups, 128)...
November 10, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29102289/in-hospital-mortality-analysis-of-japanese-patients-with-acute-coronary-syndrome-using-the-tokyo-ccu-network-database-applicability-of-the-grace-risk-score
#4
Kota Komiyama, Masato Nakamura, Kengo Tanabe, Hiroki Niikura, Hajime Fujimoto, Keiko Oikawa, Hiroyuki Daida, Takeshi Yamamoto, Ken Nagao, Morimasa Takayama
BACKGROUND: The GRACE risk score was developed to predict in-hospital mortality for acute coronary syndrome (ACS) using multinational registries, but did not include Japanese data. Therefore, GRACE risk scores are not extensively used in Japan. The present study aimed to evaluate the relationship between the GRACE risk score and in-hospital mortality among Japanese patients with ACS using the Tokyo CCU (cardiovascular care unit) Network Database. METHODS AND RESULTS: A total of 9460 patients with ACS hospitalized at 67 Tokyo CCUs between January 2011 and December 2013 were retrospectively reviewed and GRACE risk scores were calculated...
October 25, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/29059651/-the-features-of-a-functional-state-of-the-coronary-circulation-in-women-smokers-with-non-st-elevation-acute-coronary-syndrome
#5
Тетяна М Соломенчук, Артем О Бедзай, Василь В Процько
INTRODUCTION: Acute coronary syndrome is one of the most adverse prognostic clinical forms of ischemic heart disease. In recent years, attention of researchers and cardiologists practical attract female patients due to a substantial increase in the prevalence including acute coronary syndrome, differences in the causes and features of its course. Women often diagnosed myocardial infarction without ST elevation and nonobstructive coronary heart disease associated with coronary spasm or stratification of coronary artery...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29041896/-recommendations-of-the-society-of-specialists-in-urgent-cardiology-diagnosis-and-treatment-of-patients-with-non-st-segment-elevation-acute-coronary-syndrome-part-1
#6
S I YAvelov, Y M Ruda, V O Averkov, P E Panchenko
No abstract text is available yet for this article.
August 2017: Kardiologiia
https://www.readbyqxmd.com/read/29041001/hmgb1-expression-level-in-circulating-platelets-is-not-significantly-associated-with-outcomes-in-symptomatic-coronary-artery-disease
#7
Dominik Rath, Tobias Geisler, Meinrad Gawaz, Sebastian Vogel
BACKGROUND/AIMS: Platelets express high-mobility group box 1 (HMGB1), a damage-associated molecular pattern molecule (DAMP) that triggers thrombosis and inflammation when present in extracellular space. The role of platelet-derived HMGB1 in coronary artery disease (CAD) remains unexplored. METHODS: In a cohort study, we measured the expression of HMGB1 on the surface of circulating platelets in 183 patients with symptomatic CAD (stable CAD: n=80, acute coronary syndrome, ACS: n=103) at the time of percutaneous coronary intervention...
2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29033507/syntax-score-of-infarct-related-artery-other-than-the-number-of-coronary-balloon-inflations-and-deflations-as-an-independent-predictor-of-contrast-induced-acute-kidney-injury-in-patients-with-st-segment-elevation-myocardial-infarction
#8
Cheng-Wei Liu, Pen-Chih Liao, Kuo-Chin Chen, Jung-Cheng Hsu, Chung-Ming Tu, Yen-Wen Wu, Ai-Hsien Li, Shin-Rong Ke, Jiunn-Lee Lin
BACKGROUND: Although remote ischemic post-conditioning (RIPC) has been shown to prevent contrast-induced acute kidney injury (CIAKI) in patients with acute coronary syndrome, its efficacy in patients with ST-segment elevation myocardial infarction (STEMI) remains unclear. We examined the relationship among balloon inflations and deflations (BID) times, SYNTAX score of infarction-related artery (SI), periprocedural complications, and CIAKI in STEMI patients undergoing primary percutaneous coronary intervention (pPCI)...
July 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29033503/the-management-and-prognostic-factors-of-acute-coronary-syndrome-evidence-from-the-taiwan-acute-coronary-syndrome-full-spectrum-registry
#9
REVIEW
Chun-Yuan Chu, Tsung-Hsien Lin, Wen-Ter Lai
Cardiovascular disease (CVD) accounts for approximately one-third of all global deaths, and acute coronary syndrome (ACS) is the most severe form of CVD. It is of notable importance to develop ACS strategies for reducing major adverse cardiac events (MACE) and preventing complications. In the Taiwan ACS Full Spectrum Registry, 1-year mortality among patients with ST-segment elevation myocardial infarction, non ST-segment elevation myocardial infarction and unstable angina was 6.1%, 10.1%, and 6.2%, respectively...
July 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29033367/stent-implantation-and-vascular-healing-of-a-spontaneous-coronary-artery-dissection-assessed-by-optical-coherence-tomography-in-a-patient-with-acute-coronary-syndrome
#10
Kirstine Nørregaard Hansen, Lisbeth Antonsen, Lisette Okkels Jensen
A 60-year old woman with non-ST-segment elevation myocardial infarction, underwent coronary angiogram combined with optical coherence tomography (OCT) revealing a long dissection in the right coronary artery. The patient experienced peri-procedural chest pain, the electrocardiogram showed ST-segment elevations, and compromised coronary blood flow, why mechanical revascularization with percutaneous coronary intervention (PCI) was indicated. At 1-month follow-up, OCT revealed early, competent vascular healing, and a distal stenosis was treated with PCI...
September 5, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29029775/-management-of-nstemi-in-a-hospital-without-interventional-cardiology-and-without-use-of-grace-score-does-the-clinician-appreciation-match-the-grace-score-calculated-retrospectively-for-the-coronarography-delay
#11
F Bouriche, S Yvorra, A Hassan, F Paganelli, L Bonello, S Luigi, F Attia
PURPOSE: The management of non-ST segment elevation acute coronary syndromes (NSTEACS) remains an issue for mobidity, mortality, and an economic stake. The first aim of the study was to evaluate the additional value of the GRACE score for the compliance with the recommended times to coronary angiography in an hospital without interventional cardiology. We also analysed the in-hospital and 6-month mortality and the predictive factors of compliance for the coronarography delays. METHODS: Retrospective monocenter cross-sectional study including consecutive patients with chest pain suggestive of a NSTEACS during 1 year...
November 2017: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29027810/electrocardiographic-characteristics-associated-with-in-hospital-outcome-in-patients-with-left-main-acute-coronary-syndrome-for-contriving-a-new-risk-stratification-score
#12
Takayuki Iida, Fumito Tanimura, Kyoko Takahashi, Hideki Nakamura, Satoshi Nakajima, Motoyuki Nakamura, Yoshihiro Morino, Tomonori Itoh
AIM: The aim of this study was to evaluate electrocardiographic characteristics associated with in-hospital prognosis in patients with left main acute coronary syndrome. METHODS AND RESULTS: A total of 89 left main acute coronary syndrome subjects were selected from 3357 consecutive acute coronary syndrome patients (2.7%). Patients of this study were divided into two groups; those who survived and those who died. Patients' characteristics and electrocardiogram on admission were then retrospectively analyzed between the two groups...
December 1, 2016: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29020244/impact-of-total-occlusion-of-culprit-artery-in-acute-non-st-elevation-myocardial-infarction-a-systematic-review-and-meta-analysis
#13
Abdur R Khan, Harsh Golwala, Avnish Tripathi, Aref A Bin Abdulhak, Chirag Bavishi, Haris Riaz, Vishnu Mallipedi, Ambarish Pandey, Deepak L Bhatt
Aims: Total occlusion (TO) of the culprit artery usually presents with ST-elevation myocardial infarction. A subset of patients with TO present as non-ST segment elevation myocardial infarction (NSTEMI) without classic ST-elevation on the electrocardiogram. This may lead to delay in identification of these patients and further management. We performed a meta-analysis to estimate the difference in outcomes between totally occluded and non-occluded culprit arteries in patients with NSTEMI...
November 1, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28990941/influence-of-coronary-calcification-patterns-on-hemodynamic-outcome-of-coronary-stenoses-and-remodeling
#14
Ahmet Demirkıran, Ozan Çakır, Adem Atıcı, Emre Aslanger, Cansu Akdeniz, Berrin Umman, Sabahattin Umman, Zehra Bugra, Murat Sezer
OBJECTIVE: The histological characteristics of plaque may affect the hemodynamic outcome of a given coronary stenosis. In particular, the potential effect of volumetric calcium content and the topographical distribution in the lesion segment on physiological outcome has not yet been investigated. The aim of this study was to identify any potential correlation between patterns of calcification and the fractional flow reserve (FFR) and the coronary remodeling index (RMI). METHODS: A total of 26 stable angina pectoris and 34 acute coronary syndrome patients without persistent ST-segment elevation constituted the study population...
October 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28984671/early-coronary-angiography-for-survivors-of-out-of-hospital-cardiac-arrests-without-st-elevation
#15
Michael Goldfarb, Bojan Cercek
There are over 300,000 out-of-hospital cardiac arrests (OOHCA) in the United States each year, and the long-term survival rate is less than 10%. Despite improvements in postarrest management, the greatest drop-off in survival occurs during hospitalization, mostly due to myocardial dysfunction and neurological injury. Coronary artery disease is common in postcardiac arrest patients, with an incidence of approximately 60-80%. In patients with a chest pain syndrome and an ST-segment-elevation myocardial infarction pattern evident on the presenting electrocardiogram, immediate revascularization is recommended by cardiovascular societies due to established mortality benefits...
November 2017: Cardiology in Review
https://www.readbyqxmd.com/read/28982673/multivessel-versus-culprit-vessel-only-percutaneous-coronary-intervention-among-patients-with-acute-myocardial-infarction-insights-from-the-translate-acs-observational-study
#16
Homam Ibrahim, Praneet K Sharma, David J Cohen, Gregg C Fonarow, Lisa A Kaltenbach, Mark B Effron, Marjorie E Zettler, Eric D Peterson, Tracy Y Wang
BACKGROUND: Among patients with acute myocardial infarction (MI) who have multivessel disease, it is unclear if multivessel percutaneous coronary intervention (PCI) improves clinical and quality-of-life outcomes compared with culprit-only intervention. We sought to compare clinical and quality-of-life outcomes between multivessel and culprit-only PCI. METHODS AND RESULTS: Among 6061 patients with acute MI who have multivessel disease in the TRANSLATE-ACS (Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome) study, we used inverse probability-weighted propensity adjustment to study the associations between multivessel and culprit-only intervention during the index PCI and major adverse cardiovascular events, unplanned all-cause readmission, and angina frequency at 6 weeks and 1 year...
October 5, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28980282/long-term-outcomes-of-patients-with-multivessel-coronary-artery-disease-presenting-non-st-segment-elevation-acute-coronary-syndromes
#17
Piotr Desperak, Michał Hawranek, Paweł Gąsior, Aneta Desperak, Andrzej Lekston, Mariusz Gąsior
BACKGROUND: There is paucity of data concerning the optimal revascularization in patients with multivessel coronary artery disease (CAD) presenting non-ST-segment elevation acute coronary syndrome (NSTE-ACS). The aim was to evaluate long-term outcomes of patients with multivessel CAD presenting NSTE-ACS depending on the management after coronary angiography. METHODS: 3,166 patients with NSTE-ACS hospitalized between 2006-2014 were screened. After exclusions, 1,342 patients were enrolled with multivessel CAD and were divided depending on their management after coronary angiography; the medical-only therapy group (n = 91), the PCI group (n = 1,122), the CABG group (n = 129)...
October 5, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28978948/machine-learning-improves-risk-stratification-after-acute-coronary-syndrome
#18
Paul D Myers, Benjamin M Scirica, Collin M Stultz
The accurate assessment of a patient's risk of adverse events remains a mainstay of clinical care. Commonly used risk metrics have been based on logistic regression models that incorporate aspects of the medical history, presenting signs and symptoms, and lab values. More sophisticated methods, such as Artificial Neural Networks (ANN), form an attractive platform to build risk metrics because they can easily incorporate disparate pieces of data, yielding classifiers with improved performance. Using two cohorts consisting of patients admitted with a non-ST-segment elevation acute coronary syndrome, we constructed an ANN that identifies patients at high risk of cardiovascular death (CVD)...
October 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28976875/antiplatelet-therapy-in-a-patient-with-coronary-artery-disease-and-myelodysplastic-syndrome-with-thrombocytopenia
#19
Francisco José Fernández-Fernández, Eugenia Ameneiros-Lago, Cintia Tuñas-Gesto, Inmaculada Gómez-Buela
To date, there are no sufficient data to make firm recommendations on the treatment of patients with severe thrombocytopenia who require antiplatelet therapy after experiencing acute coronary syndrome. Therefore, we think that it is important to communicate the experience with individual cases. We report the case of a patient who presented with pericardial effusion causing cardiac tamponade. He had thrombocytopenia associated with myelodysplastic syndrome, and ten weeks before this admission, percutaneous transluminal coronary angioplasty with implantation of drug-eluting stents was performed for non-ST-segment elevation acute coronary syndrome...
2017: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/28965522/apical-hypertrophic-cardiomyopathy-treated-as-st-elevation-myocardial-infarction
#20
Christopher J Parr, Rajat Sharma, Philip J Garber
Electrocardiographic changes resulting from apical hypertrophic cardiomyopathy may mimic an acute coronary syndrome. A 67-year-old Sudanese male without cardiac risk factors presented to hospital with chest pain and electrocardiographic findings of septal ST-segment elevation, ST-segment depression in V4-V6, and diffuse T-wave inversion. He was treated as an acute ST-elevation myocardial infarction with thrombolytics. There was no cardiac biomarker rise and coronary angiography did not reveal evidence of significant coronary arterial disease...
October 2, 2017: CJEM
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