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acute coronary syndrome with ST segment elevation

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https://www.readbyqxmd.com/read/29778236/challenges-in-implementation-of-institutional-protocols-for-patients-with-acute-coronary-syndrome
#1
REVIEW
Atman P Shah, Sandeep Nathan
The diagnosis of acute coronary syndrome (ACS) encompasses ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation ACS (non-STEMI and unstable angina). In recent years, there have been improvements in the rates of death, cardiogenic shock, and recurrent myocardial infarction in patients with ACS, primarily due to the introduction of new pharmacological and interventional therapies, as well as the introduction of and adherence to new treatment guidelines. However, ACS still represents a considerable public health burden...
April 17, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29762500/circulating-micrornas-in-young-patients-with-acute-coronary-syndrome
#2
Kind-Leng Tong, Ahmad Syadi Mahmood Zuhdi, Wan Azman Wan Ahmad, Paul M Vanhoutte, Joao Pedro de Magalhaes, Mohd Rais Mustafa, Pooi-Fong Wong
Circulating microRNAs (miRNAs) hold great potential as novel diagnostic markers for acute coronary syndrome (ACS). This study sought to identify plasma miRNAs that are differentially expressed in young ACS patients (mean age of 38.5 ± 4.3 years) and evaluate their diagnostic potentials. Small RNA sequencing (sRNA-seq) was used to profile plasma miRNAs. Discriminatory power of the miRNAs was determined using receiver operating characteristic (ROC) analysis. Thirteen up-regulated and 16 down-regulated miRNAs were identified in young ACS patients...
May 15, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29761721/association-between-serum-s100a1-level-and-global-registry-of-acute-coronary-events-score-in-patients-with-non-st-segment-elevation-acute-coronary-syndrome
#3
Yuanmin Li, Chenjun Han, Peng Zhang, Wangfu Zang, Rong Guo
Objective Acute coronary syndrome (ACS) is associated with several clinical syndromes, one of which is acute non-ST-segment ACS (NSTE-ACS). S100A1 is a calcium-dependent regulator of heart contraction and relaxation. We investigated the association between the serum S100A1 level and the Global Registry of Acute Coronary Events (GRACE) risk score in patients with NSTE-ACS and the potential of using the serum S100A1 level to predict the 30-day prognosis of NSTE-ACS. Methods The clinical characteristics of 162 patients with NSTE-ACS were analyzed to determine the GRACE score...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29755633/coronary-artery-thromboses-stent-thrombosis-and-antiphospholipid-antibody-syndrome-case-report
#4
Augusto Ferreira Correia, Dinaldo Cavalcanti Oliveira, Marcio Sanctos
The antiphospholipid antibody syndrome (APS) is defined by a state of hypercoagulability secondary to an autoimmune disorder. There are evidences that approximately 2.8-5.5% of cases of acute myocardial infarction (AMI) in young individuals are secondary to APS. In this case report, three coronary artery thromboses occurring within a short period are described. Initially, there was an ST-segment elevation (STEMI) in the presence of coronary artery disease (CAD), with the vessel being treated with stent implantation...
April 2018: Cardiology Research
https://www.readbyqxmd.com/read/29754965/gender-based-outcome-differences-for-emergency-department-presentation-ofnon-stemi-acute-coronary-syndrome
#5
James R Langabeer, Tiffany Champagne-Langabeer, Raymond Fowler, Timothy Henry
BACKGROUND: It is known that women generally have worse mortality outcomes than men with regards to ST-segment elevation myocardial infarction. However, less is known about contemporary gender differences in non-STEMI acute coronary syndrome, particularly those presenting to emergency departments within a regionalized system of care with standardized protocols. METHODS: Retrospective registry data from 2010 to 2016 were examined from the North Texas Mission: Lifeline system of care, representing 33 hospitals around the Dallas Texas metropolitan area...
May 7, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29753418/-percutaneous-coronary-intervention-in-the-management-of-acute-coronary-syndromes-in-ivory-coast-challenges-and-outcomes
#6
R N'Guetta, A Ekou, H Yao, J B Anzouan-Kacou, B Gérardin, R Pillière, A M Adoh, R Seka
AIM: Assess the challenges and outcomes of percutaneous coronary intervention (PCI) in the management of ACS at Abidjan Heart Institute. PATIENTS AND METHODS: Prospective survey carried out from April, 1st, 2010 to April, 29th, 2016. Whole patients aged 18-year-old, admitted at Abidjan Heart Institute for ACS, and who underwent PCI were included in the Registre prospectif des actes de cardiologie interventionnelle de l'institut de cardiologie d'Abidjan (REPACI)...
May 9, 2018: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29747915/prognostic-and-practical-validation-of-current-definitions-of-myocardial-infarction-associated-with-percutaneous-coronary-intervention
#7
Pierluigi Tricoci, L Kristin Newby, Robert M Clare, Sergio Leonardi, C Michael Gibson, Robert P Giugliano, Paul W Armstrong, Frans Van de Werf, Gilles Montalescot, David J Moliterno, Claes Held, Philip E Aylward, Lars Wallentin, Robert A Harrington, Eugene Braunwald, Kenneth W Mahaffey, Harvey D White
OBJECTIVES: In 13,038 patients with non-ST-segment elevation acute coronary syndrome undergoing index percutaneous coronary intervention (PCI) in the EARLY ACS (Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome) and TRACER (Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome) trials, the relationship between PCI-related myocardial infarction (MI) and 1-year mortality was assessed. BACKGROUND: The definition of PCI-related MI is controversial...
May 14, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29747324/-prognostic-value-of-myeloperoxidase-concentration-in-patients-with-acute-coronary-syndrome
#8
S C Liu, T C Yi, H Y Weng, L Zhang, Y X Li, Momin Mohetaboer, Y Zhang, J Jiang, J P Li, Y Huo
Objective: To evaluate the difference of plasma myeloperoxidase (MPO) level in different types of acute coronary syndrome (ACS) patients, and the value of baseline MPO level in predicting short-term and long-term outcomes in patients with ACS. Methods: The study cohort was derived from "the 12th Five-Year" National Science and Technology Support Program Project "Study on Comprehensive Intervention and Prognosis of Acute Coronary Syndrome" . We enrolled all hospitalized ACS patients who were enrolled in "the 12th Five-Year" cohort from January 1, 2011 to December 31, 2013...
April 24, 2018: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29744618/association-between-central-venous-pressure-as-assessed-by-echocardiography-left-ventricular-function-and-acute-cardio-renal-syndrome-in-patients-with-st-segment-elevation-myocardial-infarction
#9
Shafik Khoury, Arie Steinvil, Amir Gal-Oz, Gilad Margolis, Aviram Hochstatd, Yan Topilsky, Gad Keren, Yacov Shacham
BACKGROUND: Recent reports have demonstrated the adverse effects of venous congestion on renal function in patients with heart failure. None of these trials, however, has evaluated the effect of acute myocardial ischemia on the occurrence of acute kidney injury (AKI). METHODS: We conducted a retrospective study of 1336 ST segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) between June 2012 and June 2016...
May 9, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29743902/early-and-long-term-outcomes-of-complete-revascularization-with-percutaneous-coronary-intervention-in-patients-with-multivessel-coronary-artery-disease-presenting-with-non-st-segment-elevation-acute-coronary-syndromes
#10
Michał Hawranek, Piotr Desperak, Paweł Gąsior, Aneta Desperak, Andrzej Lekston, Mariusz Gąsior
Introduction: The clinical significance of complete revascularization with percutaneous coronary intervention (CR-PCI) in patients with non-ST-segment acute coronary syndrome (NSTE-ACS) remains uncertain. Aim: To evaluate the impact of CR-PCI during index hospitalization on short and long-term incidence of death and composite endpoint among patients with multivessel coronary artery disease (CAD) presenting with NSTE-ACS. Material and methods: We analyzed consecutive data of 1,592 patients with multivessel CAD from 2006 to 2014...
2018: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
https://www.readbyqxmd.com/read/29736108/acute-coronary-syndrome-with-normal-coronary-arteries-a-case-of-spontaneous-spasm-lysis
#11
Vogiatzis Ioannis, Koutsambasopoulos Konstantinos, Samaras Antonios, Bostanitis Ioannis
Introduction: Patients suffering from Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) are found with no obstructive coronary artery disease on coronary arteriography. The Aim of this interesting case report is to present a patient with acute chest pain, temporal ST-segment elevation and MINOCA. Case report: A case of a young woman who presented with acute chest pain suggestive of angina, with temporal ST-segment elevation, accidentally recorded and not rising of myocardial necrosis biomarkers in blood tests is described...
April 2018: Medical Archives
https://www.readbyqxmd.com/read/29736064/psychiatric-comorbidities-in-acute-coronary-syndromes-six-month-follow-up-study
#12
D Ramya Shruthi, S Sunil Kumar, Nagaraj Desai, Rajesh Raman, T S Sathyanarayana Rao
Introduction: Acute coronary syndrome (ACS) caused by coronary atherosclerosis include ST-segment elevation myocardial infarction (STEMI), non-STEMI, and unstable angina. The relation between psychiatric disorders and coronary artery disease is a complex one which includes the effect of the psychosocial factors on heart and vice versa. Point prevalence studies have been reported, but there is paucity of follow-up studies from India. Materials and Methods: The study is a follow-up evaluation at discharge of 248 consecutive patients presented with ACS at JSS Hospital, Mysuru, Karnataka, over a period of 6 months to assess the psychiatric comorbidities...
January 2018: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/29735411/vasospastic-myocardial-infarction-complicated-with-bilateral-femoral-arteries-vasospasm
#13
Chengzhi Gao, Huapeng Yu, Daixu Li, Qiang Liu
Coronary vasospasm is an infrequent cause of acute coronary syndrome. Additionally, femoral artery spasm is not frequently encountered clinically. Here we present a case of a patient with an acute ST segment elevation myocardial infarction, secondary to a documented right coronary artery vasospasm, complicated with left coronary artery and femoral artery vasospasm. Intravenous ultrasound showed calcification at the sites of spasm. This case report indicates that coronary vasospasm should be regularly considered as part of the work up of myocardial infarction...
April 17, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29716535/predictive-value-of-neutrophil-to-lymphocyte-ratio-in-patients-with-acute-st-segment-elevation-myocardial-infarction-after-percutaneous-coronary-intervention-a-meta-analysis
#14
Sai Zhang, Jun Diao, Chunmei Qi, Jingjing Jin, Li Li, Xingjuan Gao, Lei Gong, Weiheng Wu
BACKGROUND: The neutrophil to lymphocyte ratio (NLR) is an indicator of systemic inflammation and a prognostic marker in patients with acute coronary syndrome (ACS). This study aims to investigate the value of NLR to predict the in-hospital and long-term prognosis in patients with ST segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI) by meta-analysis. METHOD: The studies related to the prognosis of NLR and STEMI patients published in the Pubmed, Embase, and Ovid databases before June 2017 were retrieved...
May 2, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29715123/takotsubo-cardiomyopathy-developed-after-two-stage-surgery-for-double-primary-lung-cancer
#15
Fumihiko Kinoshita, Gouji Toyokawa, Tetsuzo Tagawa, Taichi Matsubara, Yuka Kozuma, Naoki Haratake, Shinkichi Takamori, Takaki Akamine, Fumihiko Hirai, Yoshihiko Maehara
Takotsubo cardiomyopathy (TC) is a syndrome characterized by transient local systolic dysfunction of the left ventricle with no evidence of coronary artery disease or acute plaque rupture. We present the case of 71-year-old woman who developed TC after two-stage surgery for double primary lung cancer. On computed tomography, lung nodules were identified in the left upper and right middle lobes. Based on the diagnosis of double primary lung cancer, we performed two-stage surgery (left upper lobectomy followed by right middle lobectomy)...
May 2018: Anticancer Research
https://www.readbyqxmd.com/read/29709405/influence-of-obesity-and-metabolic-syndrome-on-clinical-outcomes-of-st-segment-elevation-myocardial-infarction-in-men-undergoing-primary-percutaneous-coronary-intervention
#16
Seung Hun Lee, Myung Ho Jeong, Ju Han Kim, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Youngkeun Ahn, Shung Chull Chae, In Whan Seong, Jong Sun Park, Jei Keon Chae, Seung Ho Hur, Kwang-Soo Cha, Hyo-Soo Kim, Hyeon Cheol Gwon, Ki Bae Seung, Seung Woon Rha
BACKGROUND: The correlation between obesity and metabolic syndrome (MetS) and its impact on cardiovascular disease remains unclear. This study aims to investigate the impact of metabolic status and obesity on clinical outcomes of male patients with ST-segment elevation myocardial infarction (STEMI). METHODS: Data from the Korea Acute Myocardial Infarction Registry-National Institutes of Health registry were used to evaluate the impact of obesity and MetS on patients undergoing primary percutaneous coronary intervention (PPCI) from November 2005 to November 2015...
April 27, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29706432/increased-risk-of-ischemic-stroke-associated-with-new-onset-atrial-fibrillation-complicating-acute-coronary-syndrome-a-systematic-review-and-meta-analysis
#17
Jiachen Luo, Hongqiang Li, Xiaoming Qin, Baoxin Liu, Jinlong Zhao, Guli Maihe, Zhiqiang Li, Yidong Wei
BACKGROUND: Atrial fibrillation has been established as a major risk factor of ischemic stroke, however, the influence of new-onset atrial fibrillation (NOAF) complicating acute coronary syndrome (ACS) on ischemic stroke remains controversial. This meta-analysis aimed to validate the association between NOAF complicating ACS and ischemic stroke. METHODS: We identified randomized controlled trials and cohort studies comparing the ischemic stroke risk between patients with NOAF and sinus rhythm after ACS by searching MEDLINE, EMBASE and Cochrane Central Register of Controlled Trials databases...
April 23, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29705375/three-year-impact-of-immediate-invasive-strategy-in-patients-with-non-st-segment-elevation-myocardial-infarction-from-the-riddle-nstemi-study
#18
Dejan Milasinovic, Aleksandra Milosevic, Zorana Vasiljevic-Pokrajcic, Jelena Marinkovic, Vladan Vukcevic, Branislav Stefanovic, Milika Asanin, Sanja Stankovic, Branislava Ivanovic, Goran Stankovic
Previous studies compared clinical outcomes of early versus delayed invasive strategy in patients with non-ST-elevation acute coronary syndrome up to 1-year follow-up, but long-term data remain scarce. Our aim was to evaluate the long-term effects of immediate invasive intervention in patients with Non-ST-Segment Elevation Myocardial Infarction (NSTEMI). The Randomized Study of Immediate Versus Delayed Invasive Intervention in Patients With Non-ST-Segment Elevation Myocardial Infarction (RIDDLE-NSTEMI) was a randomized, investigator-initiated, parallel-group trial that assigned 323 patients with NSTEMI (1:1) to either immediate (median time to intervention 1...
March 28, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29699746/characteristics-management-and-outcome-of-transient-st-elevation-versus-persistent-st-elevation-and-non-st-elevation-myocardial-infarction
#19
David S Blondheim, Michael Kleiner-Shochat, Aya Asif, Mark Kazatsker, Aaron Frimerman, Rami Abu-Fanne, Elena Neiman, Maguli Barel, Yaniv Levy, Naama Amsalem, Avraham Shotan, Simcha R Meisel
Patients with acute myocardial infarctions (AMIs) present as persistent ST-elevation myocardial infarction (STEMI) or as non-ST-segment elevation myocardial infarction (NSTEMI). In some patients with STEMI, ST elevations are transient and resolve before coronary intervention (transient ST-elevation myocardial infarction [TSTEMI]). We analyzed our registry comprising all consecutive patients with AMI admitted during 2009 to 2014, and compared the characteristics, management, and outcome of patients with TSTEMI with those of patients with STEMI and NSTEMI...
March 12, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29671864/treatment-of-patients-with-acute-coronary-syndrome-recommendations-for-medical-emergency-teams-focus-on-antiplatelet-therapies-updated-experts-standpoint
#20
Jacek Kubica, Piotr Adamski, Przemysław Paciorek, Jerzy R Ładny, Zbigniew Kalarus, Waldemar Banasiak, Wacław Kochman, Jarosław Gorący, Beata Wożakowska-Kapłon, Eliano Pio Navarese, Andrzej Kleinrok, Robert Gil, Maciej Lesiak, Jarosław Drożdż, Aldona Kubica, Krzysztof J Filipiak, Jarosław Kaźmierczak, Aleksander Goch, Stefan Grajek, Andrzej Basiński, Łukasz Szarpak, Grzegorz Grześk, Piotr Hoffman, Wojciech Wojakowski, Zbigniew Gąsior, Sławomir Dobrzycki, Jolanta M Siller-Matula, Adam Witkowski, Wiktor Kuliczkowski, Marcin Gruchała, Dariusz Timler, Grzegorz Opolski, Dariusz Dudek, Jacek Legutko, Marzenna Zielińska, Jarosław Wójcik
A group of Polish experts in cardiology and emergency medicine, encouraged by the European Society of Cardiology (ESC) guidelines, have recently published common recommendations for medical emergency teams regarding the pre-hospital management of patients with acute coronary syndrome. Due to the recent publication of the 2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation and 2017 focused update on dual antiplatelet therapy in coronary artery disease the current panel of experts decided to update the previous standpoint...
April 19, 2018: Cardiology Journal
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