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Tian-Shu Chu, Jinmei Xu
Hydrogen bonding dynamics has received extensive research attention in recent years due to the significant advances in femtolaser spectroscopy experiments and quantum chemistry calculations. Usually, photoexcitation would cause changes in the hydrogen bonding formed through the interaction between hydrogen donor and acceptor molecules on their ground electronic states, and such transient strengthening or weakening of hydrogen bonding could be crucial for the photophysical transformations and the subsequent photochemical reactions that occurred on a time scale from tens of femtosecond to a few nanoseconds...
September 2016: Journal of Molecular Modeling
Jorge L Alió del Barrio, Mohammed Ziaei, Maninder Bhogal, Bruce D Allan
PURPOSE: To review indications and clinical results for a hybrid deep lamellar endothelial keratoplasty (Femto-DLEK) technique combining contemporary donor tissue preparation and implantation techniques with femtosecond laser-assisted dissection of the host tissue. METHODS: A retrospective analysis of consecutive cases of Femto-DLEK performed between 2011 and 2014 at Moorfields Eye Hospital, London, was conducted. All patients underwent manifest refraction and optical coherence tomography examination at their most recent review visit...
November 2015: Cornea
Sri Ganesh, Sheetal Brar
No abstract text is available yet for this article.
2015: International Journal of Ophthalmology
Mukesh Taneja, Varsha M Rathi, Bhupesh Bagga
PURPOSE: To report the use of femtosecond laser platform to remove a glass foreign body (FB) and remove scar by performing sutureless lamellar keratoplasty. CASE REPORT: A 34-year-old man presented with a posttraumatic anterior stromal scar and retained corneal glass FB after injury to his left eye, sustained in a prior vehicular accident. Right eye examination was essentially normal. Best-corrected visual acuity of the left eye was 20/320. He underwent femtosecond laser-assisted sutureless anterior lamellar keratoplasty using the 500-kHz femtosecond laser machine...
February 2015: Optometry and Vision Science: Official Publication of the American Academy of Optometry
Zoltan Z Nagy
Femtosecond lasers represent a new frontier in cataract surgery. Since their introduction and first human treatment in 2008, a lot of new developments have been achieved. In this review article, the physical principle of femtolasers is discussed, together with the indications and side effects of the method in cataract surgery. The most important clinical results are also presented regarding capsulotomy, fragmentation of the crystalline lens, corneal wound creation, and refractive results. Safety issues such as endothelial and macular changes are also discussed...
2014: Clinical Ophthalmology
Darwin R Reyes, Albert Folch, Harp Minhas, Michael Gaitan
The 6th annual μTAS Art in Science Award was presented to Ye Wang of Eindhoven University of Technology at the 17th International Conference of Miniaturized Systems for Chemistry and Life Sciences held in Freiburg, Germany, on October 27-31, 2013. The winning image captivated the hearts and minds of the judges and is featured on the front cover of this issue. "Artificial Life", as the author of the work that produced this image named it, was taken with a scanning electron microscope (SEM) and shows cilia-like structures (or "microhairs") generated from PDMS (polydimethylsiloxane) and magnetic nanoparticles (Y...
April 21, 2014: Lab on a Chip
J Kacerovská, M Kacerovský, R Kadlec
PURPOSE: Compare the effect of cataract surgery with conventional phacoemulsification and cataract surgery performed on the cornea assisted by femtolaser with the help of contactless endothelial microscope. THE GROUP OF PATIENTS AND METHODS: In each group there were 25 eyes (25 patients) after the cataract surgery with conventional phacoemulsification and 25 eyes (25 patients) after cataract surgery performed on the cornea assisted by femtolaser with the help of contactless endothelial microscope...
October 2013: Ceská a Slovenská Oftalmologie
Gregor Wollensak, Christian M Hammer, Eberhard Spörl, Jörg Klenke, Katrin Skerl, Yao Zhang, Saadettin Sel
PURPOSE: The aim of this study was to assess the biomechanical efficacy of transepithelial collagen crosslinking using the femtosecond laser pocket technique compared with that using the standard crosslinking (CXL) technique. METHODS: Forty ex vivo porcine eyes were divided into 4 groups with 10 samples each. Group 1 comprised the untreated controls. Group 2 was the standard CXL group with debridement, instillation of 0.1% riboflavin-dextran solution for 15 minutes before and every 5 minutes during the 30 minutes of irradiation with ultraviolet A (UVA) light of 370 nm and an irradiance of 3 mW/cm²...
March 2014: Cornea
Hana Abouzeid
Introduced in 2008, femtolaser is playing a more and more significant role in cataract surgery. This laser allows to perform three steps of the cataract surgery: the corneal incisions, the capsulotomy, and the lens fragmentation. The prooved advantages of the technique are a better quality of the incisions with a reduced induced astigmatism, a better reliability and reproducibility of the capsulotomy with a better stability of the implanted lens and a reduction of the use of ultrasounds which can negatively affect the cornea...
December 11, 2013: Revue Médicale Suisse
Zoltán Z Nagy, Jacek P Szaflik
Having been very successful in corneal surgery, femtolasers were recently introduced into the surgery of crystalline lens. The most important indications and advantages include: perfectly centered and sized capsulotomy, liquefaction of softer lenses and fragmentation of harder lenses which allows for chopping the nucleus without the use of phaco energy. Femtolaser can also be used for creating corneal wounds (tunnels) of any size at any location, and in order to manage the preoperative astigmatism using arcuate incisions at the desired depth within the cornea...
2012: Klinika Oczna
Zoltan Z Nagy
No abstract text is available yet for this article.
December 2012: Journal of Refractive Surgery
Agnes I Takács, Illés Kovács, Kata Miháltz, Tamás Filkorn, Michael C Knorz, Zoltán Z Nagy
PURPOSE: To compare the effect of conventional phacoemulsification and femtosecond laser-assisted cataract surgery on the cornea using Scheimpflug imaging and noncontact specular microscopy. METHODS: In each group, 38 eyes (38 patients) underwent cataract surgery using either femtosecond laser-assisted (Alcon LenSx laser) (femtolaser group) or conventional phacoemulsification (phaco group). Central corneal thickness, 3-mm corneal volume, and Pentacam Nucleus Staging (PNS) were determined by a rotating Scheimpflug camera (Pentacam HR, Oculus Optikgeräte GmbH), and the volume stress index was calculated at 1 day and 1 month postoperatively...
June 2012: Journal of Refractive Surgery
Detlef Uthoff, Markus Pölzl, Daniel Hepper, Detlef Holland
PURPOSE: To investigate the outcomes of simultaneous correction of presbyopia and ametropia by a bi-aspheric cornea modulation technique, based on the creation of a central area hyperpositive for near vision and leaving the pericentral cornea for far vision in hyperopic, emmetropic, and myopic presbyopic patients. SETTING: Sixty eyes of 30 patients were treated with the PresbyMAX technique by one surgeon (D.U.) at the Eye Hospital Bellevue, Kiel, Germany. METHODS: Twenty eyes with hyperopic presbyopia, 20 eyes with emmetropic presbyopia, and 20 eyes with myopic presbyopia underwent Femto-Lasik, and were assessed up to 6 months postoperatively...
November 2012: Graefe's Archive for Clinical and Experimental Ophthalmology
Hailong Qiu, Liang Sun, Shuo Tan, Yu Sun, Shuwei Hao, Yong Yu, Weiqiang Lv, Shibin Ge, Chunhui Yang
Cubic nanocrystal and hexagonal micro-rods NaYF4, with predictable size, shape and phase, have been successfully synthesized through hydrothermal reaction. The growth mechanism and the effect of mass transfer on the morphology of hexagonal micro-prism are both discussed in detail. The increase of tri-doping lanthanide ion concentration decreased the size of crystal particle, which was explained by the Arrhenius rate equation together combined with the Gibbs-Thomson relationship. Furthermore, the dopants did not only affect the sizes of tri-doped NaYF4 micro-rods, but also impacted upon fluorescence intensity...
September 2011: Journal of Nanoscience and Nanotechnology
Alain Saad, Alice Grise-Dulac, Damien Gatinel
A patient was treated bilaterally for hyperopia (twice in the right eye and 3 times in the left eye) using laser in situ keratomileusis (LASIK) and achieved stable vision. Preoperatively, there was no known risk factor for ectasia. Three years after the last LASIK enhancement treatment, intrastromal femtolaser-assisted incisions (Intracor procedure using the Technolas femtosecond laser) were made bilaterally. After the procedure, a severe loss in the corrected distance visual acuity and in the quality of vision occurred, associated with a topography pattern suggestive of isolated anterior central protrusion...
November 2010: Journal of Cataract and Refractive Surgery
T Kohnen, O K Klaproth, V Derhartunian, D Kook
OBJECTIVE: For technical reasons, the rotating knives (microkeratomes) commonly used for flap creation in LASIK may induce cut complications such as buttonholes or incomplete flaps. Femtosecond (femto) lasers should reduce these risks because, compared with microceratomes, femtolasers work more precisely and individually, so the flap can be individualized according to the patient's eye condition. Therefore, surgery should be less of a strain to patients, vision should recover faster, and optical quality should be optimized...
May 2010: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
J Heichel, T Hammer, R Sietmann, G I W Duncker, F Wilhelm
OBJECTIVE: To demonstrate the qualities and compare the typical features of cut surfaces and cut edges created by the Femtec femtosecond laser and the Zyoptix XP microkeratome, using scanning electron microscope (SEM) pictures. METHODS: Lamellar keratotomies were performed using a femtosecond laser (40 kHz) or a microkeratome on freshly enucleated porcine eyes (n=16, eight each per technique). After special preparation, SEM images were taken to evaluate the qualities of the cut surfaces and cut edges...
April 2010: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
R Leitgeb, W Drexler, A Unterhuber, B Hermann, T Bajraszewski, T Le, A Stingl, A Fercher
We present, for the first time, in vivo ultrahigh resolution (~2.5 microm in tissue), high speed (10000 A-scans/second equivalent acquisition rate sustained over 160 A-scans) retinal imaging obtained with Fourier domain (FD) OCT employing a commercially available, compact (500x260mm), broad bandwidth (120 nm at full-width-at-half-maximum centered at 800 nm) Titanium:sapphire laser (Femtosource Integral OCT, Femtolasers Produktions GmbH). Resolution and sampling requirements, dispersion compensation as well as dynamic range for ultrahigh resolution FD OCT are carefully analyzed...
May 17, 2004: Optics Express
B Povazay, K Bizheva, B Hermann, A Unterhuber, H Sattmann, A Fercher, W Drexler, C Schubert, P Ahnelt, M Mei, R Holzwarth, W Wadsworth, J Knight, P St J Russell
In this article the ability of ultrahigh resolution ophthalmic optical coherence tomography (OCT) to image small choroidal blood vessels below the highly reflective and absorbing retinal pigment epithelium is demonstrated for the first time. A new light source (lambdac= 1050 nm, Deltalambda = 165 nm, Pout= 10 mW), based on a photonic crystal fiber pumped by a compact, self-starting Ti:Al2O3 laser has therefore been developed. Ex-vivo ultrahigh resolution OCT images of freshly excised pig retinas acquired with this light source demonstrate enhanced penetration into the choroid and better visualization of choroidal vessels as compared to tomograms acquired with a state-of-the art Ti:Al2O3 laser (Femtolasers Compact Pro, lc= 780 nm, Deltalambda= 160 nm, Pout= 400 mW), normally used in clinical studies for in vivo ultrahigh resolution ophthalmic OCT imaging...
August 25, 2003: Optics Express
Barry Cense, Erik Koperda, Jeffrey M Brown, Omer P Kocaoglu, Weihua Gao, Ravi S Jonnal, Donald T Miller
Ultrabroadband sources, such as multiplexed superluminescent diodes (SLDs) and femtosecond lasers, have been successfully employed in adaptive optics optical coherence tomography (AO-OCT) systems for ultrahigh resolution retinal imaging. The large cost differential of these sources, however, motivates the need for a performance comparison. Here, we compare the performance of a Femtolasers Integral Ti:Sapphire laser and a Superlum BroadLighter T840, using the same AO-OCT system and the same subject. In addition, we investigate the capability of our instrument equipped with the Integral to capture volume images of the fovea and adjacent regions on a second subject using the AO to control focus in the retina and custom and freeware image registration software to reduce eye motion artifacts...
March 2, 2009: Optics Express
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