Smyle

PURPOSE: Little is known about the financial burden experienced by patients receiving radiation therapy. Furthermore, currently, no financial toxicity screening tools have been validated for use in radiation oncology. METHODS AND MATERIALS: Physician surveys were used to gauge provider understanding of treatment costs and their willingness to adopt the use of financial toxicity screening tools. Post-treatment patient surveys were used to investigate the covariates of treatment-induced financial risk...

Control of microtubule dynamics underlies several fundamental processes such as cell polarity, cell division, and cell motility. To gain insights into the mechanisms that control microtubule dynamics during cell motility, we investigated the interactome of the microtubule plus-end-binding protein end-binding 1 (EB1). Via molecular mapping and cross-linking mass spectrometry we identified and characterized a large complex associating a specific isoform of myomegalin termed "SMYLE" (for short myomegalin-like EB1 binding protein), the PKA scaffolding protein AKAP9, and the pericentrosomal protein CDK5RAP2...

The purpose of this study was to identify attitudes of California physical therapy consumers toward the professional image of physical therapists. Attitudes toward the professional image of physicians were elicited for comparative purposes. Independent variables were selected to determine their influence on the perceived professional images. The results indicated that consumers viewed physical therapists as possessing four of the five criteria of professionalism; the exception was autonomy of judgment. No significant difference existed between the consumer views of the professional image of physical therapists and the professional image of physicians...

Preoperative radiation therapy is one of the major indications for the use of ionizing radiation in the treatment of malignant disease. The preoperative application of radiation treatment is given with the intention of reducing the size of bulky cancers, thus converting unresectable tumors into resectable ones. Other benefits are reduction in the risk of locoregional recurrence and in the risk of blood-borne dissemination of malignant cells promoted during surgical resection.This paper presents and discusses three cases of unresectable intrapelvic tumors initially treated by radiation therapy with the primary goal of palliation...