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Premature, neonatal, respiration,

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https://www.readbyqxmd.com/read/27125601/multiple-repeat-caesarean-deliveries-do-they-increase-maternal-and-neonatal-morbidity
#1
Senem Yaman Tunc, Elif Agacayak, Sibel Sak, Serdar Basaranoglu, Neval Yaman Goruk, Abdulkadir Turgut, Hayrettin Tay, Evindar Elci, Talip Gul
OBJECTIVE: The aim of the present study is to evaluate the effects of the increased number of caesarean deliveries (CDs) in cases of multiple repeat caesarean deliveries (MRCDs) on maternal and neonatal morbidity. METHODS: MRCDs admitted to our hospital between January 2013 and September 2014 were analysed retrospectively. A total number of 1133 women were included in the study and were divided into 4 groups. Group 1: second CDs (n = 329); Group 2: third CDs (n = 225); Group 3: fourth CDs (n = 447); Group 4: fifth CDs (n = 132)...
April 29, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/26975461/the-effects-of-kangaroo-care-in-the-neonatal-intensive-care-unit-on-the-physiological-functions-of-preterm-infants-maternal-infant-attachment-and-maternal-stress
#2
Eun-Sook Cho, Shin-Jeong Kim, Myung Soon Kwon, Haeryun Cho, Eun Hye Kim, Eun Mi Jun, Sunhee Lee
UNLABELLED: This study was conducted to identify the effects of kangaroo care on the physiological functions of preterm infants, maternal-infant attachment, and maternal stress. DESIGN AND METHODS: For this study, a quasi-experiment design was used with a nonequivalent control group, and a pre- and post-test. Data were collected from preterm infants with corrected gestational ages of ≥33weeks who were hospitalized between May and October 2011. Twenty infants were assigned to the experimental group and 20 to the control group...
July 2016: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/26845716/computerized-vital-signs-analysis-and-late-onset-infections-in-extremely-low-gestational-age-infants
#3
Leena Bhattacharya Mithal, Ram Yogev, Hannah Palac, Ilan Gur, Karen K Mestan
AIM: Current clinical and laboratory diagnostics for neonatal infection are inadequate. An infant's systemic inflammatory response may be identified earlier than clinical suspicion by a computerized algorithm (RALIS) incorporating multiple vital signs (VS). We tested the ability of RALIS to detect late onset infection (LOI) earlier than clinically suspected. METHODS: We conducted a retrospective review of infants enrolled in a birth cohort study at Prentice Women's Hospital...
July 1, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/26590570/oral-alimentation-in-neonatal-and-adult-populations-requiring-high-flow-oxygen-via-nasal-cannula
#4
Steven B Leder, Jonathan M Siner, Matthew J Bizzarro, Brian M McGinley, Maureen A Lefton-Greif
Use of high-flow oxygen via nasal cannula (HFO2-NC) is increasingly common in intensive care unit (ICU) settings. Despite the critical interface between respiration and swallowing, and the high acuity of patients in ICUs, the impact of HFO2-NC on feeding and swallowing is unknown. The present prospective, single-center, cohort study investigated the impact of HFO2-NC use on oral alimentation in neonatal and adult ICU patients. Oral alimentation status was evaluated in 100 consecutive ICU inpatients (50 neonatal and 50 adult) requiring HFO2-NC...
April 2016: Dysphagia
https://www.readbyqxmd.com/read/26583943/cardiorespiratory-events-in-preterm-infants-interventions-and-consequences
#5
J M Di Fiore, C F Poets, E Gauda, R J Martin, P MacFarlane
Stabilization of respiration and oxygenation continues to be one of the main challenges in clinical care of the neonate. Despite aggressive respiratory support including mechanical ventilation, continuous positive airway pressure, oxygen and caffeine therapy to reduce apnea and accompanying intermittent hypoxemia, the incidence of intermittent hypoxemia events continues to increase during the first few months of life. Even with improvements in clinical care, standards for oxygen saturation targeting and modes of respiratory support have yet to be identified in this vulnerable infant cohort...
April 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/26465983/early-inhaled-budesonide-for-the-prevention-of-bronchopulmonary-dysplasia
#6
RANDOMIZED CONTROLLED TRIAL
Dirk Bassler, Richard Plavka, Eric S Shinwell, Mikko Hallman, Pierre-Henri Jarreau, Virgilio Carnielli, Johannes N Van den Anker, Christoph Meisner, Corinna Engel, Matthias Schwab, Henry L Halliday, Christian F Poets
BACKGROUND: Systemic glucocorticoids reduce the incidence of bronchopulmonary dysplasia among extremely preterm infants, but they may compromise brain development. The effects of inhaled glucocorticoids on outcomes in these infants are unclear. METHODS: We randomly assigned 863 infants (gestational age, 23 weeks 0 days to 27 weeks 6 days) to early (within 24 hours after birth) inhaled budesonide or placebo until they no longer required oxygen and positive-pressure support or until they reached a postmenstrual age of 32 weeks 0 days...
October 15, 2015: New England Journal of Medicine
https://www.readbyqxmd.com/read/26375032/transplacental-administration-of-rosiglitazone-attenuates-hyperoxic-lung-injury-in-a-preterm-rabbit-model
#7
Jute Richter, Jaan Toelen, Taro Nagatomo, Julio Jimenez, Jeroen Vanoirbeek, Jan Deprest
INTRODUCTION: Continuous improvements in perinatal care have allowed the survival of increasingly more prematurely born infants. The establishment of respiration in an extremely immature yet still developing lung results in chronic lung injury with significant mortality and morbidity. We experimentally evaluated a novel medical strategy to prevent hyperoxia-induced lung injury by prenatal rosiglitazone. MATERIALS AND METHODS: Pregnant rabbits were injected with saline or rosiglitazone (3 mg/kg) 48 and 24 h prior to preterm delivery at 28 days of gestation (term = 31 days)...
2016: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/26309974/-legal-liability-for-blindness-in-an-extremely-low-birth-weight-premature-infant
#8
Petra Marschewski, Roland Uphoff
No abstract text is available yet for this article.
April 2015: Kinderkrankenschwester: Organ der Sektion Kinderkrankenpflege
https://www.readbyqxmd.com/read/26170310/three-dimensional-model-of-surfactant-replacement-therapy
#9
Marcel Filoche, Cheng-Feng Tai, James B Grotberg
Surfactant replacement therapy (SRT) involves instillation of a liquid-surfactant mixture directly into the lung airway tree. It is widely successful for treating surfactant deficiency in premature neonates who develop neonatal respiratory distress syndrome (NRDS). However, when applied to adults with acute respiratory distress syndrome (ARDS), early successes were followed by failures. This unexpected and puzzling situation is a vexing issue in the pulmonary community. A pressing question is whether the instilled surfactant mixture actually reaches the adult alveoli/acinus in therapeutic amounts...
July 28, 2015: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/26148359/-prevention-of-ventilator-associated-infection-in-neonates-with-respiratory-distress-syndrome
#10
P I Mironov, V A Rudnov
UNLABELLED: The aim of the research was to reduce the risk ventilator-associated infections (VAI) in neonates with respiratory distress syndrome. DESIGN: retrospective, observational, single center, historical control. MATERIALS AND METHODS: 113 newborns were included in the study. Ventilator-associated pneumonia was diagnosed based on the criteria of VAP CDC/NNIS. Ventilator-associated tracheobronchitis was determined on the basis of criteria of Code LRI-BRON proposed CDC National Healthcare Safety Network...
March 2015: Anesteziologiia i Reanimatologiia
https://www.readbyqxmd.com/read/26107681/outcomes-of-early-ligation-of-patent-ductus-arteriosus-in-preterms-multicenter-experience
#11
MULTICENTER STUDY
Mohamed H Ibrahim, Ahmed Azab, Naglaa M Kamal, Mostafa A Salama, Hatem H Elshorbagy, Enas A A Abdallah, Abdulrahman Hammad, Laila M Sherief
Persistent ductal patency may have serious effects in preterm infants. Analysis of the results of different trials were inconclusive in determining whether medical or surgical closure of the ductus is preferable and what is the best timing for surgical intervention.The aim of this study was to evaluate the effect of timing of surgical closure of patent ductus arteriosus (PDA) on ventilatory, hemodynamic, and nutritional status of preterm infants.The authors retrospectively looked at the outcomes of surgical ligation of PDA from January 2010 to June 2014 at 2 Saudi neonatal intensive units at 2 tertiary care centers and the authors compared the results of early ligation (before 3 weeks) to the late ligation (after 3 weeks) regarding different hemodynamic, ventilatory, and nutritional parameters...
June 2015: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26078238/optimal-timing-for-introducing-enteral-nutrition-in-the-neonatal-intensive-care-unit
#12
Jie Liu, Kaimeng Kong, Yexuan Tao, Wei Cai
OBJECTIVE: To identify the optimal time for introducing enteral nutrition to critically ill neonates. METHODS: This prospective cohort study included all eligible critically ill neonates who were admitted to a multidisciplinary tertiary neonatal intensive care unit (NICU) between 1st June and 30th November 2013. Nutrient intake and clinical outcomes during NICU stay were recorded. The effect of early (<24 hours after NICU admission) and delayed (>=24 hours) enteral nutrition introduction on clinical outcomes was assessed...
2015: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/26014693/-measurement-of-tidal-breathing-pulmonary-function-in-premature-infants-with-different-gestational-ages
#13
Ling Ji, Li-Ya Ma, Na-Na Huang
OBJECTIVE: To investigate the characteristics of the tidal breathing pulmonary function in premature infants with different gestational ages. METHODS: A total of 75 premature infants were classified into three groups according to their gestational ages: <32 weeks, 32-33(+6) weeks and 34-36(+6) weeks. Fifty-five full-term infants (39-40 weeks group) were selected as the control group. All infants were given the tidal breathing pulmonary function test at 3-5 days after birth...
May 2015: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/25946927/neonatal-outcomes-of-infants-admitted-to-a-large-government-hospital-in-amman-jordan
#14
Priya Sivasubramaniam, Cristin E Quinn, Meridith Blevins, Ahmad Al Hajajra, Najwa Khuri-Bulos, Samir Faouri, Natasha Halasa
OBJECTIVE: To describe characteristics and outcomes of Jordanian newborns admitted to a large governmental neonatal intensive care unit (NICU). METHODS: Newborns born at the government hospital, Al Bashir, in Amman, Jordan were prospectively enrolled. The study focused on newborns admitted to the NICU and a retrospective chart review was performed. Abstraction included in-hospital mortality, antibiotic days, ventilation, oxygen use, and CRP levels. Rank sum and chi-squared tests were used to compare across outcomes...
2015: Global Journal of Health Science
https://www.readbyqxmd.com/read/25944197/the-potential-harms-and-benefits-from-research-on-medical-practices
#15
COMMENT
Benjamin S Wilfond, David C Magnus
No abstract text is available yet for this article.
May 2015: Hastings Center Report
https://www.readbyqxmd.com/read/25944196/the-author-replies
#16
COMMENT
Robert M Nelson
No abstract text is available yet for this article.
May 2015: Hastings Center Report
https://www.readbyqxmd.com/read/25944195/muddled-measures-of-risks-and-misremembered-reasons
#17
COMMENT
John D Lantos, Chris Feudtner
No abstract text is available yet for this article.
May 2015: Hastings Center Report
https://www.readbyqxmd.com/read/25944194/what-counts-as-equipoise
#18
COMMENT
Henry J Silverman, Didier Dreyfuss
No abstract text is available yet for this article.
May 2015: Hastings Center Report
https://www.readbyqxmd.com/read/25928880/still-births-neonatal-deaths-and-neonatal-near-miss-cases-attributable-to-severe-obstetric-complications-a-prospective-cohort-study-in-two-referral-hospitals-in-uganda
#19
Annettee Nakimuli, Scovia N Mbalinda, Rose C Nabirye, Othman Kakaire, Sarah Nakubulwa, Michael O Osinde, Nelson Kakande, Dan K Kaye
BACKGROUND: Neonatal near miss cases occur more often than neonatal deaths and could enable a more comprehensive analysis of risk factors, short-term outcomes and prognostic factors in neonates born to mothers with severe obstetric complications. The objective was to assess the incidence, presentation and perinatal outcomes of severe obstetric morbidity in two referral hospitals in Central Uganda. METHODS: A prospective cohort study was conducted between March 1, 2013 and February 28, 2014, in which all newborns from cases of severe pregnancy and childbirth complications were eligible for inclusion...
2015: BMC Pediatrics
https://www.readbyqxmd.com/read/25785789/elective-high-frequency-oscillatory-ventilation-versus-conventional-ventilation-for-acute-pulmonary-dysfunction-in-preterm-infants
#20
REVIEW
Filip Cools, Martin Offringa, Lisa M Askie
BACKGROUND: Respiratory failure due to lung immaturity is a major cause of mortality in preterm infants. Although the use of intermittent positive pressure ventilation (IPPV) in neonates with respiratory failure saves lives, its use is associated with lung injury and chronic lung disease. A newer form of ventilation called high frequency oscillatory ventilation has been shown in experimental studies to result in less lung injury. OBJECTIVES: The objective of this review was to determine the effect of the elective use of high frequency oscillatory ventilation (HFOV) as compared to conventional ventilation (CV) on the incidence of chronic lung disease (CLD), mortality and other complications associated with prematurity and assisted ventilation in preterm infants who were mechanically ventilated for respiratory distress syndrome (RDS)...
2015: Cochrane Database of Systematic Reviews
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