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https://www.readbyqxmd.com/read/29667689/no-unjamming-transition-in-a-voronoi-model-of-biological-tissue
#1
Daniel M Sussman, Matthias Merkel
Vertex models are a popular approach to simulating the mechanical and dynamical properties of dense biological tissues, describing the tissue as a network of polygons. Recently a class of two-dimensional vertex models was shown to exhibit a disordered rigidity transition controlled by the preferred cellular geometry, which was subsequently echoed by experimental findings. An attractive variant of these models uses a Voronoi tessellation to describe the cells, which reduces the number of degrees of freedom as compared the original vertex model...
April 18, 2018: Soft Matter
https://www.readbyqxmd.com/read/29667250/a-new-2d-echocardiographic-approach-to-evaluate-the-membrane-and-valve-movement-of-the-berlin-heart-excor-vad-chamber-in-pediatric-vad-patients
#2
Arianna Di Molfetta, Roberta Iacobelli, Gianfranco Ferrari, Sergio Filippelli, Gianluigi Perri, Alessandra Toscano, Rachele Adorisio, Paolo Guccione, Antonio Amodeo
The use of Berlin Heart EXCOR VAD (BH) is a validated therapy to bridge pediatric patients to heart transplant. Serial echocardiographic (ECHO) assessment of VAD patients is necessary to support patients' management. This work aims at developing an innovative strategy to evaluate the BH device functioning by ECHO and its interaction with the native heart in a pediatric population. ECHO evaluation of BH membrane movement, and inflow and outflow valves was performed in 2D, 2D-color Doppler, M-mode, and M-mode color Doppler to assess the functioning of the device by direct positioning of the ECHO probe on the BH cannulas and membranes...
April 2018: Artificial Organs
https://www.readbyqxmd.com/read/29642694/integrated-quadruple-stress-echocardiography
#3
Eugenio Picano, Doralisa Morrone, Maria C Scali, Alda Huqi, Katia Coviello, Quirino Ciampi
Stress Echocardiography (SE) is an established diagnostic technique. For 40 years, the cornerstone of the technique has been the detection of regional wall motion abnormalities (RWMA), due to the underlying physiologically-relevant epicardial coronary artery stenosis. In the last decade, three new parameters (more objective than RWMA) have shown the potential to integrate and comple- ment RWMA: 1- B-lines, also known as ultrasound lung comets, as a marker of extra-vascular lung water, measured using lung ultrasound with the 4-site simplified scan symmetrically of the antero- lateral thorax on the third intercostal space, from mid-axillary to anterior axillary and mid- clavicular line; 2-left ventricular contractile reserve (LVCR), assessed as the peak stress/rest ratio of left ventricular force, also known as elastance (systolic arterial pressure by cuff sphygmomanome- ter/end-systolic volume from 2D echocardiography); 3- coronary flow velocity reserve (CFVR) on left anterior descending coronary artery, calculated as peak stress/rest ratio of diastolic peak flow velocity assessed using pulsed-wave Doppler...
April 11, 2018: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29607567/shear-strain-rate-from-phase-contrast-velocity-encoded-mri-application-to-study-effects-of-aging-in-the-medial-gastrocnemius-muscle
#4
Usha Sinha, Vadim Malis, Robert Csapo, Marco Narici, Shantanu Sinha
BACKGROUND: Strain rate (SR) is a measure of the rate of regional deformation that can be computed by analyzing velocity-encoded phase-contrast 2D images. Recent studies have explored the changes in normal components of the strain tensor in aging muscle, while shear strain may also provide valuable information. PURPOSE: To compute the shear SR from velocity-encoded MRI of the lower leg and to study the correlation of SR parameters measured in the medial gastrocnemius (MG) to muscle force in a cohort of young and senior subjects...
April 1, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29605969/latent-myopathy-is-more-pronounced-in-patients-with-low-flow-versus-normal-flow-aortic-stenosis-with-normal-left-ventricular-ejection-fraction-who-are-undergoing-surgical-aortic-valve-replacement-multicenter-study-with-a-brief-review-of-the-literature
#5
Azhar Supariwala, Monica Sanchez-Ross, Valentin Suma, Karthik Seetharam, Daniel Marrero, Daniel Swistel, Sandhya Balaram, Farooq A Chaudhry
BACKGROUND: Midwall fibrosis and low stroke volume are independent predictors of mortality in severe aortic stenosis (AS) with preserved LV ejection fraction (LVEF). The role of speckle tracking echocardiography (STE) to identify latent myopathy pre- and post- aortic valve replacement (AVR) in high risk AS patients with normal LVEF is limited. METHODS: Demographic, 2D echocardiographic, and STE data were analyzed in patients with severe AS and preserved LVEF who underwent tissue AVR...
April 1, 2018: Echocardiography
https://www.readbyqxmd.com/read/29605902/three-dimensional-full-automated-software-in-the-evaluation-of-the-left-ventricle-function-from-theory-to-clinical-practice
#6
Valentina Barletta, Rocio Hinojar, Alejandra Carbonell, Ariana González-Gómez, Iacopo Fabiani, Vitantonio Di Bello, José Julio Jiménez-Nacher, José Zamorano, Covadonga Fernández-Golfín
Left ventricular systolic function evaluation is an essential part of all transthoracic echocardiographic (TTE) studies. 3D echocardiography (3DE) is superior to 2D and is recommended as the method of choice. However, since it is time consuming and requires training, it is rarely performed. Different automatic analysis software tries to overcome these limitations but they need to be accurate and reproducible before they can be used clinically. The aim of this study was to test the accuracy and reproducibility of new 3D automatic quantitative software in everyday clinical practice...
March 31, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29605381/type-2-diabetes-patients-have-accelerated-cartilage-matrix-degeneration-compared-to-diabetes-free-controls-data-from-the-osteoarthritis-initiative
#7
Jan Neumann, Felix C Hofmann, Ursula Heilmeier, Walid Ashmeik, Kenneth Tang, Alexandra S Gersing, Benedikt J Schwaiger, Michael C Nevitt, Gabby B Joseph, Nancy E Lane, Charles E McCulloch, Thomas M Link
PURPOSE: Osteoarthritis (OA) and diabetes mellitus (DM) share common risk factors with a potential underlying relationship between both diseases. The purpose of this study was to investigate the longitudinal effects of DM on cartilage deterioration over 24-months with MR-based T2 relaxation time measurements. METHODS: From the Osteoarthritis Initiative cohort 196 diabetics were matched in small sets for age, sex, BMI and Kellgren-Lawrence score with 196 non-diabetic controls...
March 29, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29603487/comparison-between-3d-isotropic-and-2d-conventional-mr-arthrography-for-diagnosing-rotator-cuff-tear-and-labral-lesions-a-meta-analysis
#8
Sun Hwa Lee, Seong Jong Yun, Wook Jin, So Young Park, Ji Seon Park, Kyung Nam Ryu
BACKGROUND: Although 3D-isotropic MR arthrography has been characterized as a substitute imaging tool for rotator cuff tear (RCT) and labral lesions, it has not been commonly used in clinical practice because of controversy related to image blurring and indistinctness of structural edges. PURPOSE: To perform a comparison of the diagnostic performance of 3D-isotropic MR arthrography and 2D-conventional MR arthrography for diagnosis of RCT (solely RCT, full/partial-thickness supraspinatus [SST]-infraspinatus [IST] tear, or subscapularis [SSc] tear) and labral lesions...
March 30, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29594809/presence-of-the-posterior-pituitary-bright-spot-sign-on-mri-in-the-general-population-a-comparison-between-1-5-and-3t-mri-and-between-2d-t1-spin-echo-and-3d-t1-gradient-echo-sequences
#9
Verena Klyn, Sven Dekeyzer, Ruth Van Eetvelde, Pieter Roels, Ortwin Vergauwen, Pieter Devolder, Martin Wiesmann, Eric Achten, Omid Nikoubashman
PURPOSE: To describe the prevalence of the posterior pituitary bright spot (PPBS) in the general population on 1.5 and 3T MRI examinations and on 2D-T1 spin-echo (SE) and 3D-T1 gradient-echo (GE) sequences. MATERIALS AND METHODS: 1017 subjects who received an MRI of the brain for aspecific neurological complaints were included. MRI was performed on 1.5T in 64.5% and on 3T in 35.5% of subjects. Presence of the PPBS was evaluated on sagittal 2D T1-SE echo images with slice thickness 3 mm in 67...
March 28, 2018: Pituitary
https://www.readbyqxmd.com/read/29584598/use-of-2d-u-net-convolutional-neural-networks-for-automated-cartilage-and-meniscus-segmentation-of-knee-mr-imaging-data-to-determine-relaxometry-and-morphometry
#10
Berk Norman, Valentina Pedoia, Sharmila Majumdar
Purpose To analyze how automatic segmentation translates in accuracy and precision to morphology and relaxometry compared with manual segmentation and increases the speed and accuracy of the work flow that uses quantitative magnetic resonance (MR) imaging to study knee degenerative diseases such as osteoarthritis (OA). Materials and Methods This retrospective study involved the analysis of 638 MR imaging volumes from two data cohorts acquired at 3.0 T: (a) spoiled gradient-recalled acquisition in the steady state T1ρ -weighted images and (b) three-dimensional (3D) double-echo steady-state (DESS) images...
March 27, 2018: Radiology
https://www.readbyqxmd.com/read/29580616/increasing-robustness-of-radial-grase-acquisition-for-sar-reduced-brain-imaging
#11
Melisa Okanovic, Michael Völker, Robert Trampel, Felix Breuer, Peter Jakob, Martin Blaimer
PURPOSE: To improve a radial multi-slice 2D gradient- and spin-echo (GRASE) sequence and provide an appropriate image reconstruction technique for SAR-reduced high-resolution neuroimaging. METHODS: Additional readout gradients per radio-frequency (RF) refocusing allow for a reduced number of RF pulses. In this way, a specific absorption rate (SAR) reduction is achieved and the application at high-field systems becomes more feasible. A phase insensitive image reconstruction is proposed to reduce signal dropout artifacts originating from opposite readout polarities...
March 23, 2018: Zeitschrift Für Medizinische Physik
https://www.readbyqxmd.com/read/29570513/three-dimensional-echocardiographic-ventricular-mass-end-diastolic-volume-ratio-in-native-hypertensive-patients-relation-between-stroke-volume-and-geometry
#12
Maria Lembo, Roberta Esposito, Ciro Santoro, Francesco Lo Iudice, Vincenzo Schiano-Lomoriello, Valeria Fazio, Maria Gabriella Grimaldi, Bruno Trimarco, Giovanni de Simone, Maurizio Galderisi
BACKGROUND: Elevated left ventricular (LV) mass/end-diastolic volume ratio (LVM/EDV) has been associated with higher evidence of myocardial fibrosis and dysfunction in hypertensive patients by cardiac magnetic resonance, a technique with limited availability. OBJECTIVES: We investigated the ability of three-dimensional (3D) echocardiography in identifying a phenotype of LV concentric geometry according to LVM/EDV ratio, possibly detecting early myocardial damage in native-hypertensive patients...
March 22, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29569741/the-effects-of-navigator-distortion-and-noise-level-on-interleaved-epi-dwi-reconstruction-a-comparison-between-image-and-k-space-based-method
#13
Erpeng Dai, Zhe Zhang, Xiaodong Ma, Zijing Dong, Xuesong Li, Yuhui Xiong, Chun Yuan, Hua Guo
PURPOSE: To study the effects of 2D navigator distortion and noise level on interleaved EPI (iEPI) DWI reconstruction, using either the image- or k-space-based method. METHODS: The 2D navigator acquisition was adjusted by reducing its echo spacing in the readout direction and undersampling in the phase encoding direction. A POCS-based reconstruction using image-space sampling function (IRIS) algorithm (POCSIRIS) was developed to reduce the impact of navigator distortion...
March 23, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29567351/interatrial-block-to-predict-atrial-fibrillation-in-myotonic-dystrophy-type-1
#14
Vincenzo Russo, Andrea Antonio Papa, Anna Rago, Carmine Ciardiello, Marco Marano, Riccardo Proietti, Luisa Politano, Gerardo Nigro
Paroxysmal atrial fibrillation frequently occurs in Myotonic dystrophy type 1 (DM1) patients. Interatrial block is recognized as predictor of atrial arrhythmias, particularly atrial fibrillation (AF). The aim of this study was to evaluate the role of interatrial block in predicting the onset of atrial fibrillation during 2-year follow-up in DM1 patients who underwent pacemaker implantation for conduction system disorders. The study prospectively enrolled 70 DM1 patients (aged 36-69; 31 M) who underwent pacemaker implantation for cardiac rhythm abnormalities in accordance with the current guidelines...
January 31, 2018: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/29565646/a-mechanism-for-3d-semi-automated-myocardium-boundary-detection-using-displacement-encoding-with-stimulated-echoes-dense
#15
Julia Karr, Xiaodong Zhong, Michael V Cohen, Angela Judice-Yates, Eduardo Rel, Maria S Figarola
OBJECTIVE: Displacement ENcoding with Stimulated Echoes (DENSE) is a MRI technique developed to encode phase related to myocardial tissue displacements, and the displacement information directly applied towards detecting left-ventricular (LV) myocardial motion during the cardiac cycle. The purpose of this study is to present a novel, 3D DENSE displacement-based and magnitude image quantization-based, semi-automated detection technique for myocardial wall motion whose boundaries are used for rapid and automated computation of 3D myocardial strain...
March 22, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29561895/untangling-the-r2-contrast-in-multiple-sclerosis-a-combined-mri-histology-study-at-7-0-tesla
#16
Francesca Bagnato, Simon Hametner, Emma Boyd, Verena Endmayr, Yaping Shi, Vasiliki Ikonomidou, Guanhua Chen, Siddharama Pawate, Hans Lassmann, Seth Smith, E Brian Welch
T2*-weighted multi-echo gradient-echo magnetic resonance imaging and its reciprocal R2* are used in brain imaging due to their sensitivity to iron content. In patients with multiple sclerosis who display pathological alterations in iron and myelin contents, the use of R2* may offer a unique way to untangle mechanisms of disease. Coronal slices from 8 brains of deceased multiple sclerosis patients were imaged using a whole-body 7.0 Tesla MRI scanner. The scanning protocol included three-dimensional (3D) T2*-w multi-echo gradient-echo and 2D T2-w turbo spin echo (TSE) sequences...
2018: PloS One
https://www.readbyqxmd.com/read/29554708/bioactive-segetane-ingenane-and-jatrophane-diterpenes-from-euphorbia-taurinensis
#17
Dóra Rédei, Norbert Kúsz, Gréta Sátori, Annamária Kincses, Gabriella Spengler, Katalin Burián, Zoltán Barina, Judit Hohmann
A novel segetane (1: ) and jatrophane diterpene (2: ), together with five known diterpenoids possessing segetane (3: ), jatrophane (4: ), and ingenane skeletons (5 - 7: ), were isolated from the methanol extract of Euphorbia taurinensis All. The structure elucidation of the compounds was performed by means of extensive spectroscopic analysis, including HRESIMS and 1D (1 H, J -modulated spin-echo carbon experiment) and 2D (HSQC, HMBC, COSY, NOESY) NMR experiments. The multidrug resistance reversing and cytotoxic effects of five diterpenes (1, 4:  - 7: ) were studied on the L5178 mouse lymphoma cell line using rhodamine 123 accumulation and the MTT cell viability assay...
March 19, 2018: Planta Medica
https://www.readbyqxmd.com/read/29526564/normative-data-for-left-and-right-ventricular-systolic-strain-in-healthy-caucasian-italian-children-by-two-dimensional-speckle-tracking-echocardiography
#18
Massimiliano Cantinotti, Marco Scalese, Raffaele Giordano, Eliana Franchi, Nadia Assanta, Marco Marotta, Cecilia Viacava, Sabrina Molinaro, Giorgio Iervasi, Giuseppe Santoro, Martin Koestenberger
BACKGROUND: There is an increasing interest in echocardiographic strain (ε) measurements for the assessment of ventricular myocardial function in children; however, pediatric nomograms remain limited. Our aim was to establish pediatric nomograms for the left ventricular (LV) and the right ventricular (RV) ε measured by two-dimensional speckle-tracking echocardiography (2D-STE) in a large cohort of healthy children prospectively enrolled. METHODS: Echocardiographic measurements included STE LV longitudinal and circumferential and RV longitudinal global end-systolic ε...
March 8, 2018: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29524248/a-2d-spiral-turbo-spin-echo-technique
#19
Zhiqiang Li, John P Karis, James G Pipe
PURPOSE: 2D turbo-spin-echo (TSE) is widely used in the clinic for neuroimaging. However, the long refocusing radiofrequency pulse train leads to high specific absorption rate (SAR) and alters the contrast compared to conventional spin-echo. The purpose of this work is to develop a robust 2D spiral TSE technique for fast T2 -weighted imaging with low SAR and improved contrast. METHODS: A spiral-in/out readout is incorporated into 2D TSE to fully take advantage of the acquisition efficiency of spiral sampling while avoiding potential off-resonance-related artifacts compared to a typical spiral-out readout...
March 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29523179/a-young-female-presenting-with-heart-failure-secondary-to-eosinophilic-myocarditis-a-case-report-and-review-of-the-literature
#20
Dissanayake Mudiyanselage Priyantha Udaya Kumara Ralapanawa, Kulatunga Wijekoon Mudiyanselage Pramitha Prabhashini Kumarihamy, Miriyalini Sundararajah, Widana Arachchilage Thilak Ananda Jayalath
BACKGROUND: Eosinophilic myocarditis is one of the fatal complications of idiopathic hypereosinophilic syndromes. Given the rarity of this form of myocarditis, it is often under-recognized. We describe a young girl who presented with features of heart failure. To our knowledge, this is the first reported case of eosinophilic myocarditis in a young Sri Lankan female. CASE PRESENTATION: A previously healthy 21 year old Sri Lankan female admitted with shortness of breath for 1 week duration with associated low grade fever and profuse sweating...
March 9, 2018: BMC Research Notes
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