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https://www.readbyqxmd.com/read/28534200/atrophy-of-calf-muscles-by-unloading-results-in-an-increase-of-tissue-sodium-concentration-and-fat-fraction-decrease-a-23-na-mri-physiology-study
#1
D A Gerlach, K Schopen, P Linz, B Johannes, J Titze, J Zange, J Rittweger
PURPOSE: (23)Na MRI demonstrated increased tissue sodium concentrations in a number of pathologies. Acute atrophy results in muscle fibre volume shrinking that may result in a relative increase of extracellular volume and might affect sodium concentration. Thus, we hypothesized that local unloading of the calf muscles would lead to a decrease in muscle volume and an increase in muscle tissue sodium concentration. METHOD: One lower leg of 12 healthy male subjects was submitted to a 60 day long period of unloading using the Hephaistos orthosis, while the other leg served as control...
May 22, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28528267/using-mri-to-non-invasively-and-accurately-quantify-preoperative-hepatic-steatosis
#2
Callisia N Clarke, Haesun Choi, Ping Hou, Catherine H Davis, Jingfei Ma, Asif Rashid, Jean-Nicolas Vauthey, Thomas A Aloia
BACKGROUND: The obesity epidemic has significantly increased the incidence and severity of hepatic steatosis in liver surgery patients and liver donors, potentially impacting postoperative liver regeneration and function. Development of a non-invasive means to quantify hepatic steatosis would facilitate selection of candidates for liver resection and transplant donation. METHODS: An IRB-approved protocol prospectively enrolled 28 patients with liver tumors requiring hepatic resection...
May 17, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28524543/snapshot-whole-brain-t1-relaxometry-using-steady-state-prepared-spiral-multislice-variable-flip-angle-imaging
#3
Rahel Heule, Josef Pfeuffer, Oliver Bieri
PURPOSE: Variable flip angle (VFA) imaging is widely used for whole-brain T1 quantification. Because of the requirement to acquire at least two sets of MR images at different flip angles, VFA relaxometry is relatively slow. Here, whole-brain VFA T1 mapping at 1.5 T is accelerated by using efficient spiral non-Cartesian imaging METHODS: To quantify T1 in the human brain, radiofrequency spoiled gradient-echo imaging is performed at two optimized flip angles using an interleaved 2D multislice sequence with high spoiling efficiency...
May 19, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28513892/assessment-of-nonarteritic-anterior-ischemic-optic-neuropathy-with-intravoxel-incoherent-motion-diffusion-weighted-imaging-using-readout-segmented-echo-planar-imaging-parallel-imaging-and-2d-navigator-based-reacquisition
#4
Ping Lu, Yan Sha, Hailin Wan, Feng Wang, Guohong Tan, Wenlin Tang
PURPOSE: To determine the feasibility of intravoxel incoherent motion (IVIM) for characterizing perfusion properties and its potential diagnostic utility for nonarteritic anterior ischemic optic neuropathy (NAION). IVIM diffusion-weighted imaging is a promising technique that can measure perfusion and diffusion characteristics simultaneously in a noninvasive manner. MATERIALS AND METHODS: Orbital IVIM in a 3.0T scanner was performed on 33 patients with NAION and 15 controls using readout-segmented echo-planar imaging, parallel imaging, and 2D navigator-based reacquisition (RESOLVE-IVIM)...
May 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28491295/magnetic-resonance-imaging-planning-in-children-with-complex-congenital-heart-disease-a-new-approach
#5
Israel Valverde, Tarinee Tangcharoen, Tarique Hussain, Hubrecht de Bliek, Graeme Penney, Marcel Breeuwer, Tobias Schaeffter, Reza Razavi, Gerald Greil
OBJECTIVES: To compare a standard sequential 2D Planning Method (2D-PM) with a 3D offline Planning Method (3D-PM) based on 3D contrast-enhanced magnetic resonance angiography (CE-MRA) in children with congenital heart disease (CHD). DESIGN: In 14 children with complex CHD (mean: 2.6 years, range: 3 months to 7.6 years), axial and coronal cuts were obtained with single slice spin echo sequences to get the final double oblique longitudinal cut of the targeted anatomical structure (2D-PM, n = 31)...
January 2017: JRSM Cardiovascular Disease
https://www.readbyqxmd.com/read/28489309/isotropic-three-dimensional-t2-mapping-of-knee-cartilage-development-and-validation
#6
Roberto Colotti, Patrick Omoumi, Gabriele Bonanno, Jean-Baptiste Ledoux, Ruud B van Heeswijk
PURPOSE: 1) To implement a higher-resolution isotropic 3D T2 mapping technique that uses sequential T2 -prepared segmented gradient-recalled echo (Iso3DGRE) images for knee cartilage evaluation, and 2) to validate it both in vitro and in vivo in healthy volunteers and patients with knee osteoarthritis. MATERIALS AND METHODS: The Iso3DGRE sequence with an isotropic 0.6 mm spatial resolution was developed on a clinical 3T MR scanner. Numerical simulations were performed to optimize the pulse sequence parameters...
May 10, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28488622/family-with-ehlers-danlos-syndrome-combined-classic-and-vascular-type-with-rare-presentation-of-progressive-myopathy-and-unusual-association-of-severe-facial-and-trigeminal-motor-weakness
#7
A Nalini, N Devaraddi, N Gayathri, Chandrajit Prasad, V Preethish-Kumar, K Polavarapu, S Shantanu
We report the clinical, radiological, biochemical, muscle histology, and electron microscopic features of two members of a family with combined Ehlers-Danlos syndrome (EDS) [classic and vascular type] and progressive myopathy as the primary manifestation. A 35-year old lady presented with severe gluteal and thigh muscle pain and easy fatigability for 5 years. She developed weakness and wasting of pelvic and pectoral girdles and thighs for 3 years and severe neck flexor and truncal weakness for 6 months. She had a history of recurrent jaw dislocation, easy bruising with hyperpigmentation, hyperextensibility of joints, translucent skin, and papyraceous scars...
May 2017: Neurology India
https://www.readbyqxmd.com/read/28475712/surgical-management-of-aortopulmonary-window-24-years-of-experience-and-lessons-learned
#8
Deepak Gowda, Trushar Gajjar, Jinaga Nageswar Rao, Praveen Chavali, Aaditya Sirohi, Naveen Pandarinathan, Neelam Desai
OBJECTIVES: Aortopulmonary window represents 0.2-0.3% of all congenital heart lesions. Progressive pulmonary arterial hypertension and its consequences are more common with this anomaly. The purpose of this study was to share 24 years of surgical experience in managing a spectrum of 55 cases of aortopulmonary window, followed up to 17 years in a single institution. METHODS: : This retrospective study was done from November 1991 to November 2015 of 55 patients with aortopulmonary window who underwent successful surgical repair...
May 5, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28474393/dynamic-1-h-imaging-of-hyperpolarized-1-13-c-lactate-in-vivo-using-a-reverse-inept-experiment
#9
Jiazheng Wang, Felix Kreis, Alan J Wright, Richard L Hesketh, Malcolm H Levitt, Kevin M Brindle
PURPOSE: Dynamic magnetic resonance spectroscopic imaging of hyperpolarized (13) C-labeled cell substrates has enabled the investigation of tissue metabolism in vivo. Currently observation of these hyperpolarized substrates is limited mainly to (13) C detection. We describe here an imaging pulse sequence that enables proton observation by using polarization transfer from the hyperpolarized (13) C nucleus to spin-coupled protons. METHODS: The pulse sequence transfers (13) C hyperpolarization to (1) H using a modified reverse insensitive nuclei enhanced by polarization transfer (INEPT) sequence that acquires a fully refocused echo...
May 5, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28470915/comparison-of-fast-acquisition-strategies-in-whole-heart-four-dimensional-flow-cardiac-mr-two-center-1-5-tesla-phantom-and-in-vivo-validation-study
#10
Pankaj Garg, Jos J M Westenberg, Pieter J van den Boogaard, Peter P Swoboda, Rahoz Aziz, James R J Foley, Graham J Fent, F G J Tyl, L Coratella, Mohammed S M ElBaz, R J van der Geest, David M Higgins, John P Greenwood, Sven Plein
PURPOSE: To validate three widely-used acceleration methods in four-dimensional (4D) flow cardiac MR; segmented 4D-spoiled-gradient-echo (4D-SPGR), 4D-echo-planar-imaging (4D-EPI), and 4D-k-t Broad-use Linear Acquisition Speed-up Technique (4D-k-t BLAST). MATERIALS AND METHODS: Acceleration methods were investigated in static/pulsatile phantoms and 25 volunteers on 1.5 Tesla MR systems. In phantoms, flow was quantified by 2D phase-contrast (PC), the three 4D flow methods and the time-beaker flow measurements...
May 4, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28460762/acute-pulmonary-thromboembolism-epidemiology-predictors-and-long-term-outcome-a-single-center-experience
#11
U M Nagamalesh, V S Prakash, K C Karthik Naidu, S Sarthak, Anupama V Hegde, T Abhinay
INTRODUCTION: Acute pulmonary thromboembolism (PTE) is a life-threatening disease. Mortality in PTE still remains very high in spite of progress in diagnostic tools. Mortality rate is about 30% in patients with unrecognized acute PTE. METHODS: It is a single center observational study of 31 consecutive patients who were hospitalized in the Department of Cardiology at MS Ramaiah Memorial hospital between January 1, 2010 and June 2015. All the patients confirmed with diagnosis of acute PTE by CT scan (either HRCT or CTPA) were included in the study...
March 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28460192/proton-density-fat-fraction-of-rotator-cuff-muscles-is-associated-with-isometric-strength-10-years-after-rotator-cuff-repair-a-quantitative-magnetic-resonance-imaging-study-of-the-shoulder
#12
Dimitrios C Karampinos, Christian Holwein, Stefan Buchmann, Thomas Baum, Stefan Ruschke, Alexandra S Gersing, Reto Sutter, Andreas B Imhoff, Ernst J Rummeny, Pia M Jungmann
BACKGROUND: Quantitative muscle fat-fraction magnetic resonance (MR) imaging techniques correlate with semiquantitative Goutallier scores with failure after rotator cuff (RC) repair. PURPOSE: To investigate the relationship of proton density fat fraction (PDFF) of the RC muscles with semiquantitative MR scores, cartilage T2 relaxation times, and clinical isometric strength measurements in patients 10 years after unilateral RC repair. STUDY DESIGN: Cross-sectional study; Level of evidence, 3...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28456274/a-specific-absorption-rate-reduction-method-for-simultaneous-multislice-magnetic-resonance-imaging
#13
Fu-Hsing Wu, Edzer L Wu, Yi-Hang Tung, Po-Wei Cheng, Tzi-Dar Chiueh, Jyh-Horng Chen
This study proposes a modified Shinnar-Le Roux method to synthesize the excitation radio frequency (RF) pulse for a 2D gradient echo (GRE) based simultaneous multi-slice (SMS) magnetic resonance imaging (MRI) with features of low specific absorption rate (SAR) and small out-of-slice ripple. This synthesis method for SMS RF pulses employs thinner slice bandwidth and lower multislice offset frequencies to reduce SAR values and adopts a weighted Parks-McClellan algorithm to reduce sidelobes. Formulas for estimating relative SAR values of the SMS pulses are also introduced...
April 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28448406/two-dimensional-spoiled-gradient-recalled-echo-magnetic-resonance-imaging-of-the-liver-using-respiratory-navigator-gating-techniques
#14
Yusuke Inoue, Hirofumi Hata, Keiji Matsunaga, Ai Nakajima, Shotaro Komi, Yutaka Abe, Hiroki Miyatake
OBJECTIVE: We assessed the feasibility of T1-weighted 2-dimensional spoiled gradient-recalled (2D SPGR) acquisition in steady-state imaging of the liver with various respiratory navigator gating techniques. METHODS: A total of 12 healthy volunteers underwent in-phase and out-of-phase 2D SPGR imaging of the liver during breath-holding and free-breathing. Four techniques for respiratory navigation, 2 conventional navigator techniques and 2 self-navigator techniques, were used for free-breathing imaging...
April 26, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28444805/2d-multi-spectral-imaging-for-fast-mri-near-metal
#15
Brian A Hargreaves, Valentina Taviani, Daniel V Litwiller, Daehyun Yoon
PURPOSE: To develop a fast 2D method for MRI near metal with reduced B0 in-plane and through-slice artifacts. METHODS: Multi-spectral imaging (MSI) approaches reduce artifacts in MR images near metal, but require 3D imaging of multiple excited volumes regardless of imaging geometry or artifact severity. The proposed 2D MSI method rapidly excites a limited slice and spectral region using gradient reversal between excitation and refocusing pulses, then uses standard 2D imaging, with the process repeating to cover multiple spectral offsets that are combined as in other MSI techniques...
April 25, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28438984/comparison-of-multiple-non-invasive-methods-of-measuring-cardiac-output-during-pregnancy-reveals-marked-heterogeneity-in-the-magnitude-of-cardiac-output-change-between-women
#16
John W Petersen, Jing Liu, Yueh-Yun Chi, Melissa Lingis, R Stan Williams, Alice Rhoton-Vlasak, Mark S Segal, Kirk P Conrad
Various non-invasive methods are available to measure cardiac output (CO) during pregnancy. We compared serial measures of CO using various methods to determine which provided the least variability. Ten patients with spontaneous pregnancy had estimation of CO at baseline prior to becoming pregnant and at the end of the first and third trimesters. Echocardiographic data were used to estimate CO using the Teichholz method, Simpson's biplane method, and the Doppler determined velocity time integral (VTI) method...
April 2017: Physiological Reports
https://www.readbyqxmd.com/read/28438666/how-to-choose-the-right-mr-sequence-for-your-research-question-at-7-t-and-above
#17
José P Marques, David G Norris
The choice of a pulse sequence at ultra-high field can be influenced by a number of considerations and constraints that are not always the same as those at lower fields. Foremost amongst these is of course the information required and the time available, but considerations of static main field- and transmit field- inhomogeneities as well as power deposition can also play an important role. In this review we first briefly examine the characteristics of high field MRI, and then describe the performance and constraints relevant to the major imaging readouts, and their implementation with parallel imaging techniques...
April 21, 2017: NeuroImage
https://www.readbyqxmd.com/read/28433557/early-changes-of-left-ventricular-filling-pattern-after-reperfused-st-elevation-myocardial-infarction-and-doxycycline-therapy-insights-from-the-tiptop-trial
#18
Giampaolo Cerisano, Piergiovanni Buonamici, Guido Parodi, Alberto Santini, Guia Moschi, Renato Valenti, Angela Migliorini, Paolo Colonna, Benedetta Bellandi, Anna Maria Gori, David Antoniucci
AIM: Metalloproteinases inhibition by doxycycline reduces cardiac protein degradation at extracellular and intracellular level in the experimental model ischemia/reperfusion injury. Since both extracellular cardiac matrix and titin filaments inside the cardiomyocyte are responsible for the myocardial stiffness, we hypothesized that doxycycline could favorably act on left ventricular (LV) filling pressures in patients after reperfused acute ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS: Seventy-three of 110 patients of the TIPTOP trial underwent a 2D-Echo-Doppler on admission, and at pre-discharge and at 6-month after a primary PCI for STEMI and LV dysfunction...
April 7, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28424572/functional-sensitivity-of-2d-simultaneous-multi-slice-echo-planar-imaging-effects-of-acceleration-on-g-factor-and-physiological-noise
#19
Nick Todd, Oliver Josephs, Peter Zeidman, Guillaume Flandin, Steen Moeller, Nikolaus Weiskopf
Accelerated data acquisition with simultaneous multi-slice (SMS) imaging for functional MRI studies leads to interacting and opposing effects that influence the sensitivity to blood oxygen level-dependent (BOLD) signal changes. Image signal to noise ratio (SNR) is decreased with higher SMS acceleration factors and shorter repetition times (TR) due to g-factor noise penalties and saturation of longitudinal magnetization. However, the lower image SNR is counteracted by greater statistical power from more samples per unit time and a higher temporal Nyquist frequency that allows for better removal of spurious non-BOLD high frequency signal content...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28415115/p981lvot-area-measurement-using-gated-ct-data-reclassifies-aortic-stenosis-severity-as-graded-by-echocardiography
#20
L Moderato, A Palumbo, S Coli, D Orlandini, G Russo, N Gaibazzi
Background: Measurement of left ventricular outflow tract (LVOT) diameter and area for estimation of aortic valve area (AVA) using transthoracic echocardiography (TTE) and the continuity equation assumes circular LVOT. The use of direct planimetric measurement of LVOT area by gated-CT can theoretically improve accuracy of AVA calculation. Purpose: We aim to assess reproducibility of LVOT echo measurement and its correlation and agreement with Gated CT measurements...
December 1, 2016: European Heart Journal Cardiovascular Imaging
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