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https://www.readbyqxmd.com/read/28419246/quality-assurance-for-a-multicenter-phase-ii-study-of-stereotactic-ablative-radiotherapy-for-hepatocellular-carcinoma-%C3%A2-5-cm-a-planning-dummy-run
#1
Sun Hyun Bae, Mi-Sook Kim, Won Il Jang, Kum Bae Kim, Kwang Hwan Cho, Woo Chul Kim, Chang Yeol Lee, Eun Seog Kim, Chul Won Choi, A Ram Chang, Sunmi Jo, Jin-Young Kim
Objective: The Korean Radiation Oncology Group (12-02) investigated the outcome of stereotactic ablative radiotherapy for hepatocellular carcinoma ≤5 cm using 60 Gy in three fractions. To evaluate dosimetric differences and compliance in a multicenter trial, a planning dummy run procedure was performed. Methods: All six participating institutions were provided the contours of two dummy run cases. Plans were performed following the study protocol to cover the planning target volume with a minimum of 90% of the prescription dose and to satisfy the constraints for organs at risk...
April 13, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28410684/knowledge-based-treatment-planning-an-inter-technique-and-inter-system-feasibility-study-for-prostate-cancer
#2
Elisabetta Cagni, Andrea Botti, Renato Micera, Maria Galeandro, Roberto Sghedoni, Matteo Orlandi, Cinzia Iotti, Luca Cozzi, Mauro Iori
PURPOSE: Helical Tomotherapy (HT) plans were used to create two RapidPlan knowledge-based (KB) models to generate plans with different techniques and to guide the optimization in a different treatment planning system for prostate plans. Feasibility and performance of these models were evaluated. MATERIAL AND METHODS: two sets of 35 low risk (LR) and 30 intermediate risk (IR) prostate cancer cases who underwent HT treatments were selected to train RapidPlan models...
April 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28383157/development-of-a-novel-low-radiation-absorbent-lok-bar-to-reduce-x-ray-scattering-and-absorption-in-rapidarc-%C3%A2-treatment-planning-and-dose-delivery
#3
Hajime Monzen, Kazuki Kubo, Mikoto Tamura, Masaru Hayakawa, Yasumasa Nishimura
We developed a novel low-radiation-absorbent lok-bar (HM-bar) that is used to secure the immobilizers to the couch. The aim of this study was to investigate the X-ray scattering and absorption properties of the HM-bar in computed tomography (CT) simulation and radiotherapy dose delivery using the Varian Exact™ lok-bar (VL-bar) as a benchmark. CT images were obtained with or without lok-bar, and then each image was visually evaluated for artifacts. The attenuation rates for each lok-bar were measured using a farmer-type ionization chamber (PTW30013) and the I'mRT phantom (IBA Dosimetry GmbH)...
April 6, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28335778/radiation-dose-escalation-based-on-fdg-pet-driven-dose-painting-by-numbers-in-oropharyngeal-squamous-cell-carcinoma-a-dosimetric-comparison-between-tomotherapy-ha-and-rapidarc
#4
Sarah Differding, Edmond Sterpin, Nicolas Hermand, Bianca Vanstraelen, Sandra Nuyts, Nathalie de Patoul, Jean-Marc Denis, John Aldo Lee, Vincent Grégoire
PURPOSE: Validation of dose escalation through FDG-PET dose painting (DP) for oropharyngeal squamous cell carcinoma (SCC) requires randomized clinical trials with large sample size, potentially involving different treatment planning and delivery systems. As a first step of a joint clinical study of DP, a planning comparison was performed between Tomotherapy HiArt® (HT) and Varian RapidArc® (RA). METHODS: The planning study was conducted on five patients with oropharyngeal SCC...
March 23, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28297456/is-the-dose-distribution-distorted-in-imrt-and-rapidarc-treatment-when-patient-plans-are-swapped-across-beam-matched-machines
#5
Chockkalingam Krishnappan, Chandrasekaran Anu Radha, Vendhan Subramani, Madhan Kumar Gunasekaran
The purpose of this study is to evaluate the degree of dose distribution distortion in advanced treatments like IMRT and RapidArc when patient plans are swapped across dosimetrically equivalent so-called "beam-matched" machines. For this purpose the entire work is divided into two stages. At forefront stage all basic beam properties of 6 MV X-rays like PDD, profiles, output factors, TPR20/10 and MLC transmission of two beam-matched machines - Varian Clinac iX and Varian 600 C/D Unique - are compared and evaluated for differences...
September 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297441/comprehensive-dosimetric-planning-comparison-for-early-stage-non-small-cell-lung-cancer-with-sabr-fixed-beam-imrt-versus-vmat-versus-tomotherapy
#6
Ilma Xhaferllari, Omar El-Sherif, Stewart Gaede
Volumetric-modulated arc therapy (VMAT) is emerging as a leading technology in treating early-stage, non-small cell lung cancer (NSCLC) with stereotactic ablative radiotherapy (SABR). However, two other modalities capable of delivering intensity-modulated radiation therapy (IMRT) include fixed-beam and helical TomoTherapy (HT). This study aims to provide an extensive dosimetric comparison among these various IMRT techniques for treating early-stage NSCLC with SABR. Ten early-stage NSCLC patients were retrospectively optimized using three fixed-beam techniques via nine to eleven beams (high and low modulation step-and-shoot (SS), and sliding window (SW)), two VMAT techniques via two partial arcs (SmartArc (SA) and RapidArc (RA)), and three HT techniques via three different fan beam widths (1 cm, 2...
September 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28291927/single-fraction-radiosurgery-stereotactic-body-radiation-therapy-sbrt-for-spine-metastasis-a-dosimetric-comparison-of-multiple-delivery-platforms
#7
Adrian Nalichowski, Isaac Kaufman, John Gallo, Todd Bossenberger, Tim Solberg, Ezequiel Ramirez, Yulong Yan, Julie Fredrick, Tewfik Bichay, Alan Mayville, Jay Burmeister
There are numerous commercial radiotherapy systems capable of delivering single fraction spine radiosurgery/SBRT. We aim to compare the capabilities of several of these systems to deliver this treatment when following standardized criteria from a national protocol. Four distinct target lesions representing various case presentations of spine metastases were contoured in both the thoracic and lumbar spine of an anthropomorphic SBRT phantom. Single fraction radiosurgery/SBRT plans were designed for each target with each of our treatment platforms...
January 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28279147/dosimetric-comparison-and-evaluation-of-4-stereotactic-body-radiotherapy-techniques-for-the-treatment-of-prostate-cancer
#8
Jan Seppälä, Sami Suilamo, Mikko Tenhunen, Liisa Sailas, Heli Virsunen, Erna Kaleva, Jani Keyriläinen
PURPOSE: The aim of this study was to compare dosimetric characteristics, monitor unit, and delivery efficiency of 4 different stereotactic body radiotherapy techniques for the treatment of prostate cancer. METHODS: This study included 8 patients with localized prostate cancer. Dosimetric assets of 4 delivery techniques for stereotactic body radiotherapy were evaluated: robotic CyberKnife, noncoplanar intensity-modulated radiotherapy, and 2 intensity-modulated arc therapy techniques (RapidArc and Elekta volumetric-modulated arc therapy)...
April 2017: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/28241884/radiotherapy-of-nasopharyngeal-cancer-using-rapidarc-dosimetric-study-of-military-teaching-hospital-mohamed-v-morocco
#9
Issam Lalya, El Amin Marnouche, Maghous Abdelhak, Noha Zaghba, Khalid Andaloussi, Mohamed Elmarjany, Laila Baddouh, Keltoum Dahmani, Khalid Hadadi, Hassan Sifat, Hamid Mansouri
BACKGROUND: The aim of the present study is to assess efficacy and efficiency of Volumetric-modulated arc therapy (VMAT) technique in treatment of nasopharyngeal cancer in our institution and to report toxicity related to this technique. METHODS: Between June 2013 and January 2015, thirty-two patients with non metastatic nasopharyngeal cancer were curatively treated using VMAT Rapidarc. Dose prescription was performed using two different schedules, it consisted of either simultaneous integrated boost or simultaneous modulated accelerated radiation therapy delivering 70 Gy in 35 fractions and 69...
February 28, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28237181/moderate-hypofractionated-postprostatectomy-volumetric-modulated-arc-therapy-with-daily-image-guidance-vmat-igrt-a%C3%A2-mono-institutional-report-on-feasibility-and-acute-toxicity
#10
Sergio Fersino, Umberto Tebano, Rosario Mazzola, Niccolò Giaj-Levra, Francesco Ricchetti, Gioacchino Di Paola, Alba Fiorentino, Gianluisa Sicignano, Stefania Naccarato, Ruggero Ruggieri, Stefano Cavalleri, Filippo Alongi
INTRODUCTION: The aim of this study was to evaluate the acute toxicity profiles of a moderate hypofractionated regimen with volumetric modulated arc therapy (VMAT) in patients with prostate cancer (PC) who underwent radical prostatectomy. MATERIAL AND METHODS: From December 2012 to February 2016, 125 patients, previously having undergone radical prostatectomy, received adjuvant (64 patients) or salvage (61 patients) radiotherapy (RT) inside an institutional protocol of moderate hypofractionation schedule using the VMAT technique (Varian RapidArc, Palo Alto, CA)...
February 6, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28228330/assessment-of-monitor-unit-limiting-strategy-using-volumetric-modulated-arc-therapy-for-cancer-of-hypopharynx
#11
Shabbir Ahamed, Navin Singh, Deleep Gudipudi, Suneetha Mulinti, Anil Talluri, Bhudevi Soubhagya, Madhusudhana Sresty
PURPOSE: To quantify relative merit of MU deprived plans against freely optimized plans in terms of plan quality and report changes induced by progressive resolution optimizer algorithm (PRO3) to the dynamic parameters of RapidArc. MATERIALS AND METHODS: Ten cases of carcinoma hypopharynx were retrospectively planned in three phases without using MU tool. Replicas of these baseline plans were reoptimized using "Intermediate dose" feature and "MU tool" to reduce MUs by 20%, 35%, and 50%...
March 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28114239/clinical-outcomes-of-stereotactic-body-radiotherapy-in-oligometastatic-gynecological-cancer
#12
Concetta Laliscia, Maria Grazia Fabrini, Durim Delishaj, Riccardo Morganti, Carlo Greco, Martina Cantarella, Roberta Tana, Fabiola Paiar, Angiolo Gadducci
OBJECTIVE: The objective of this study was to assess the role of stereotactic body radiotherapy (SBRT) in the treatment of distantly recurrent, oligometastatic gynecological cancer. METHODS: The hospital records of 45 patients with F-fluorodeoxyglucose (F-FDG) positron emission tomography positive, distantly recurrent, oligometastatic gynecological cancer were reviewed. All these patients had a number of target lesions less than 5, with largest diameter less than 6 cm...
February 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28048624/su-f-t-284-the-effect-of-linear-accelerator-output-variation-on-the-quality-of-patient-specific-rapid-arc-verification-plans
#13
G Sandhu, F Cao, S Szpala, K Kohli
PURPOSE: The aim of the current study is to investigate the effect of machine output variation on the delivery of the RapidArc verification plans. METHODS: Three verification plans were generated using Eclipse™ treatment planning system (V11.031) with plan normalization value 100.0%. These plans were delivered on the linear accelerators using ArcCHECK- device, with machine output 1.000 cGy/MU at calibration point. These planned and delivered dose distributions were used as reference plans...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048534/su-f-t-584-investigating-correction-methods-for-ion-recombination-effects-in-octavius-1000-srs-measurements
#14
C Knill, M Snyder, J Rakowski, L Zhuang, M Matuszak, Burmeister J
PURPOSE: PTW's Octavius 1000 SRS array performs IMRT QA measurements with liquid filled ionization chambers (LICs). Collection efficiencies of LICs have been shown to change during IMRT delivery as a function of LINAC pulse frequency and pulse dose, which affects QA results. In this study, two methods were developed to correct changes in collection efficiencies during IMRT QA measurements, and the effects of these corrections on QA pass rates were compared. METHODS: For the first correction, Matlab software was developed that calculates pulse frequency and pulse dose for each detector, using measurement and DICOM RT Plan files...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048350/su-f-p-30-clinical-assessment-of-auto-beam-hold-triggered-by-fiducial-localization-during-prostate-rapidarc-delivery
#15
P Atkinson, Q Chen
PURPOSE: To assess the clinical efficacy of auto beam hold during prostate RapidArc delivery, triggered by fiducial localization on kV imaging with a Varian True Beam. METHODS: Prostate patients with four gold fiducials were candidates in this study. Daily setup was accomplished by aligning to fiducials using orthogonal kV imaging. During RapidArc delivery, a kV image was automatically acquired with a momentary beam hold every 60 degrees of gantry rotation. The position of each fiducial was identified by a search algorithm and compared to a predetermined 1...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048260/su-f-p-37-implementation-of-an-end-to-end-qa-test-of-the-radiation-therapy-imaging-planning-and-delivery-process-to-identify-and-correct-possible-sources-of-deviation
#16
F Salinas Aranda, V Suarez, S Arbiser, R Sansogne
PURPOSE: To implement an end-to-end QA test of the radiation therapy imaging, planning and delivery process, aimed to assess the dosimetric agreement accuracy between planned and delivered treatment, in order to identify and correct possible sources of deviation. To establish an internal standard for machine commissioning acceptance. METHODS: A test involving all steps of the radiation therapy: imaging, planning and delivery process was designed. The test includes analysis of point dose and planar dose distributions agreement between TPS calculated and measured dose...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047896/su-f-t-339-comparison-between-coplanar-and-non-coplanar-rapidarc-approach-of-hippocampal-sparing-whole-brain-radiotherapy
#17
B Liu, J Kim
PURPOSE: To compare the dosimetry of coplanar and non-coplanar RapidArc whole brain plans for hippocampal sparing METHODS: We studied the RapidArc plans of patient with brain metastases, with the prescription of 3750 cGy in 15 fractions. The coplanar approach used a full clockwise (CW) arc and a full counterclockwise (CCW) arc, with the couch angle to be 0°. The non-coplanar approach used a full arc with a couch angle of 0°, and a partial arc with a couch angle of 90°. Treatment planning system is Eclipse Ver...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047842/su-f-t-420-dosimetry-comparison-of-advanced-external-beam-radiation-treatment-modalities-to-brachytherapy-treatments-in-patients-with-cervical-cancer
#18
U Mwidu, S Devic, M Shehadeh, M AlKafi, R Mahmood, B Moftah
PURPOSE: A retrospective comparison of dose distributions achievable by High dose rate brachytherapy (HDRBT), Helical TomoTherapy (TOMO), CyberKnife (CK) and RapidArc (RA) in locally advanced inoperable cervical cancer patients is presented. METHODS: Five patients with advanced stage cervical carcinoma were selected for this study after a full course of external beam radiotherapy (EBRT), chemotherapy and HDR Brachytherapy. To highlight any significant similarities/differences in dose distributions, high-risk clinical target volume (HRCTV) coverage, organs at risk (OAR) sparing, and machine specific delivery limitations, we used D90 (dose received by 90% of the volume) as the parameter for HRCTV coverage as recommended by the GEC-ESTRO Working Group...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047283/su-f-t-344-commissioning-constant-dose-rate-vmat-in-the-raystation-treatment-planning-system-for-a-varian-clinac-ix
#19
J Pursley, G Gueorguiev, H Prichard, D Gierga
PURPOSE: To demonstrate the commissioning of constant dose rate volumetric modulated arc therapy (VMAT) in the Raystation treatment planning system for a Varian Clinac iX with Exact couch. METHODS: Constant dose rate (CDR) VMAT is an option in the Raystation treatment planning system, enabling VMAT delivery on Varian linacs without a RapidArc upgrade. Raystation 4.7 was used to commission CDR-VMAT for a Varian Clinac iX. Raystation arc model parameters were selected to match machine deliverability characteristics...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047095/su-f-t-531-determination-of-site-specific-dynamic-jaw-versus-static-jaw-rapidarc-delivery
#20
C Tien, M Brewer, M Studenski
PURPOSE: Dynamic-jaw tracking maximizes the area blocked by both jaw and MLC in RapidArc. We developed a method to quantify jaw tracking. METHODS: An Eclipse Scripting API (ESAPI) was used to export beam parameters for each arc's control points. The specific beam parameters extracted were: gantry angle, control point number, meterset, x-jaw positions, y-jaw positions, MLC bank-number, MLC leaf-number, and MLC leaf-position. Each arc contained 178 control points with 120 MLC positions...
June 2016: Medical Physics
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