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Prospective memory

Lana Hamieh, Rana R McKay, Xun Lin, Ronit Simantov, Toni K Choueiri
BACKGROUND: Poor-risk patients with metastatic renal-cell carcinoma remain poorly characterized in prospective clinical trials. Therefore, we sought to provide a comprehensive analysis of this patient population, defined by 3 widely used prognostic models, treated with targeted therapy. PATIENTS AND METHODS: We conducted a pooled retrospective analysis of 4736 metastatic renal-cell carcinoma patients treated on phase 2 and 3 clinical trials. Poor-risk patients were defined according to the Memorial Sloan Kettering Cancer Center (MSKCC), International Metastatic Renal Cell Carcinoma Database Consortium (IMDC), and Hudes risk models...
August 12, 2017: Clinical Genitourinary Cancer
D Draaisma
From the age of about 60, many people begin to experience difficulties with tasks that require the use of prospective memory and begin to have trouble finding words and names. Worried that these symptoms may be indicative of the onset of Alzheimer's disease, many of them fill in online self-tests or consult their family doctor. In the vast majority of cases, symptoms like these indicate completely natural age-related forgetfulness. Physicians should encourage a socially active lifestyle to slow down further decline...
2017: Nederlands Tijdschrift Voor Geneeskunde
Yu-Xi Song, Wen-Yi Tong, Yu-Hao Shen, Shijing Gong, Z Tang, Chun-Gang Duan
Considerable progress in contemporary spintronics has been made in recent years for developing nanoscale data memory and quantum information processing. It is, however, still a great challenge to achieve the ultimate limit of storage bit. Two-dimensional materials, fortunately, provide an alternative solution to design materials with the expected miniaturizing scale, the chemical stability as well as the giant magnetic anisotropy energy. By performing first-principles calculations, we have examined two possible doping sites on WS<sub>2</sub> monolayer using three kind of transition metal (TM) atoms (Mn, Fe and Co)...
September 14, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Massimiliano Fabbiani, Antonio Muscatello, Paolo Perseghin, Marco Bani, Arianna Incontri, Nicola Squillace, Giuseppe Lapadula, Andrea Gori, Alessandra Bandera
BACKGROUND: The contribution of monocyte activation in the development of HIV-associated neurocognitive disorders is not completely understood. This study aimed to explore the predictive value of peripheral monocyte/macrophage (M/M) phenotypes on the evolution of cognitive performance in a population of virologically suppressed HIV-infected patients. SETTING: Prospective, observational, longitudinal study. METHODS: HIV-1-infected patients with HIV-RNA <50copies/mL for >12 months underwent neuropsychological examination at baseline and after 1 year...
October 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
Sweta Tiwari, Maja-Lisa Løchen, Bjarne K Jacobsen, Laila A Hopstock, Audhild Nyrnes, Inger Njølstad, Ellisiv B Mathiesen, Kjell A Arntzen, Jocasta Ball, Simon Stewart, Tom Wilsgaard, Henrik Schirmer
BACKGROUND: Previous studies have shown associations between atrial fibrillation (AF) and cognitive decline. We investigated this association in a prospective population study, focusing on whether stroke risk factors modulated this association in stroke-free women and men. METHODS: We included 4983 participants (57% women) from the 5(th) survey of the Tromsø Study (Tromsø 5, 2001), of whom 2491 also participated in 6(th) survey (Tromsø 6, 2007-08). Information about age, education, blood pressure, body mass index, lipids, smoking, coffee consumption, physical activity, depression, coronary and valvular heart disease, heart failure and diabetes was obtained at baseline...
September 13, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
Kees Okkersen, Melanie Buskes, Johannes Groenewoud, Roy P C Kessels, Hans Knoop, Baziel van Engelen, Joost Raaphorst
OBJECTIVE: To examine the cognitive profile of patients with myotonic dystrophy type 1 (DM1) on the basis of a systematic review and meta-analysis of the literature. METHODS: Embase, Medline and PsycInfo were searched for studies reporting ≥1 neuropsychological test in both DM1 patients and healthy controls. Search, data extraction and risk of bias analysis were independently performed by two authors to minimize error. Neuropsychological tests were categorized into 12 cognitive domains and effect sizes (Hedges' g) were calculated for each domain and for tests administered in ≥5 studies...
August 16, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
John Guinane, Boon Lung Ng
BACKGROUND: Despite of their limited availability and potential for significant variation between and within each modality, this is the first study to prospectively measure the clinical utility of MRI and/or SPECT brain scanning in addition to the routine diagnostic workup of patients presenting to memory clinic. METHODS: A single center study was conducted over a convenience of 12-month sampling period. For each patient referred for MRI and/or SPECT scanning, the primary geriatrician or psychogeriatrician was asked to assign an initial diagnosis...
September 7, 2017: International Psychogeriatrics
Luciana de Almeida Silva Teixeira, Fabiana Prado Dos Santos Nogueira, Gabriel Antonio Nogueira Nascentes
Dengue is an arboviral infection clinically recognized as an acute and self-limited disease. Persistence of dengue symptoms is known, but it has been little studied. The aim of this study was to characterize persistent symptoms in 113 patients with dengue followed up clinically and by laboratory testing at a tertiary hospital. Symptoms that persisted for more than 14 days were observed in 61 (54.0%) patients, and six (6.2%) of them had symptoms for 6 months or more. The persistent symptoms identified were myalgia, weakness, hair loss, memory loss, reduced resistance to physical effort, headache, reasoning problems, arthralgia, sleepiness- and emotional lability...
September 4, 2017: Revista do Instituto de Medicina Tropical de São Paulo
Kristina B Beck, Matthias-Claudio Loretto, Max Ringler, Walter Hödl, Andrius Pašukonis
Animals relying on uncertain, ephemeral and patchy resources have to regularly update their information about profitable sites. For many tropical amphibians, widespread, scattered breeding pools constitute such fluctuating resources. Among tropical amphibians, poison frogs (Dendrobatidae) exhibit some of the most complex spatial and parental behaviors-including territoriality and tadpole transport from terrestrial clutches to ephemeral aquatic deposition sites. Recent studies have revealed that poison frogs rely on spatial memory to successfully navigate through their environment...
2017: PeerJ
Daniele S J Volpe, Nátali C A C Oliveira, A Carlos Santos, Maria B M Linhares, Ana P C P Carlotti
OBJECTIVES: To evaluate neuropsychological outcome after traumatic brain injury (TBI) and its association with trauma severity and late magnetic resonance imaging (MRI) findings. METHODS: Prospective cohort study of patients with TBI admitted to the paediatric intensive care unit over 5 years. Trauma severity was determined by Glasgow Coma Scale (GCS), neurological outcome by King's Outcome Scale for Childhood Head Injury (KOSCHI) and neuropsychological outcome by Wechsler Intelligence Scale for Children - Fourth Edition...
September 5, 2017: Brain Injury: [BI]
Amanda J Cross, Johnson George, Michael C Woodward, David Ames, Henry Brodaty, Rory Wolfe, Michael H Connors, Rohan A Elliott
BACKGROUND: There is limited evidence regarding the association between potentially inappropriate medications (PIM) and mortality in older people with cognitive impairment. OBJECTIVE: To examine whether use of medications considered to be potentially inappropriate in older people with cognitive impairment (PIMcog) and anticholinergic cognitive burden (ACB) were associated with mortality in people who attended memory clinics. METHODS: Cross-sectional and longitudinal analyses of data from the Prospective Research In MEmory clinics (PRIME) study...
September 1, 2017: Journal of Alzheimer's Disease: JAD
D Bäckström, M Eriksson Domellöf, G Granåsen, J Linder, S Mayans, E Elgh, H Zetterberg, K Blennow, L Forsgren
OBJECTIVES: Cognitive decline is common in Parkinson's disease (PD), but the underlying mechanisms for this complication are incompletely understood. Genotypes affecting dopamine transmission may be of importance. This study investigates whether genotypes associated with reduced prefrontal dopaminergic tone and/or reduced dopamine D2-receptor availability (Catechol-O-methyltransferase [COMT] Val(158) Met genotype and DRD2 C(957) T genotype) affect the development of cognitive deficits in PD...
September 4, 2017: Acta Neurologica Scandinavica
Mary E Mihuta, Heather J Green
PURPOSE: Low engagement and high attrition are common challenges in web-based interventions. Typical measures of engagement reported in the literature are not meaningful for describing participant activity within the intervention and can be misleading. This research aimed to develop a more meaningful method of measuring engagement in an online cognitive rehabilitation program whilst monitoring treatment fidelity. METHODS: A pilot study and randomised controlled trial (RCT) were conducted...
September 2, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Yan Liu, Yanjie Su, Guoqing Xu, Meng Pei
Recent research on comparative metacognition shows that animals, like humans, can differentiate between what they know and what they do not know. However, not much is known about the metacognitive behaviors of human children during their early years. To explore the emergence of memory-monitoring skills, two experiments were conducted using nonverbal tasks adapted from the work of Kornell, Son, and Terrace (2007) and Hampton (2001). Experiment 1 endeavored to determine when children began to show the ability to monitor their memories retrospectively...
August 29, 2017: Journal of Experimental Child Psychology
Gabriela Cruz, Pablo Burgos, Kerry Kilborn, Jonathan J Evans
OBJECTIVE: Time-based prospective memory (PM), remembering to do something at a particular moment in the future, is considered to depend upon self-initiated strategic monitoring, involving a retrieval mode (sustained maintenance of the intention) plus target checking (intermittent time checks). The present experiment was designed to explore what brain regions and brain activity are associated with these components of strategic monitoring in time-based PM tasks. METHOD: 24 participants were asked to reset a clock every four minutes, while performing a foreground ongoing word categorisation task...
2017: PloS One
J Lee, G Štrkalj
Acquiring adequate resources for anatomy education has represented a challenge throughout the discipline's long history. A significant number of collections housed in anatomy departments contain human tissue of unknown provenance with some obtained in morally dubious ways. This paper outlines the history and future prospects of one such anatomical assemblage - the Burns Anatomical Collection, currently housed at the University of Maryland (UM). The collection originally contained more than 1000 anatomically prepared mummified human remains...
August 31, 2017: Journal of Postgraduate Medicine
A Kretschmer-Trendowicz, K M Schnitzspahn, L Reuter, M Altgassen
Research on children's prospective memory (PM) shows an increase of performance across childhood and provides first evidence that encoding strategies such as episodic future thinking (EFT; i.e., engaging in a vivid prospection of oneself performing future tasks) may improve performance. The present study aimed at testing whether the beneficial effects of EFT extend from typical lab-based tasks to more complex tasks with real life demands. Further, it was tested whether children's ability to project themselves into different perspectives (i...
August 31, 2017: Psychological Research
Milvia Cottini, Demis Basso, Paola Palladino
Prospective memory (PM) develops considerably during the primary school years (7 or 8years of age). Developmental changes have been mainly related to executive functions, although it has been recently suggested that PM would also potentially benefit from metamemory (MM). To date, only procedural MM, operationalized as performance predictions, has been investigated in relation to PM, whereas declarative MM has remained unexplored. Adults' performance has been shown to improve with predictions, but only in a resource-demanding (i...
August 28, 2017: Journal of Experimental Child Psychology
Sheng-Fong Kuo, Tsung-Ying Ho, Miaw-Jene Liou, Kun-Ju Lin, Ru-Chin Cheng, Sheng-Chieh Chan, Bie-Yui Huang, Soh-Ching Ng, Feng-Hsuan Liu, Hung-Yu Chang, Sheng-Hwu Hsieh, Kun-Chun Chiang, Huang-Yang Chen, Ta-You Lo, Chih-Lang Lin, Jen-Der Lin
There were insufficient data regarding radiation exposure to the household environment from patients with thyroid cancer who received radioactive iodine (RAI) therapy in Asia; we therefore performed the present study at the Chang Gung Memorial Hospital in Keelung, Taiwan.Patients with papillary or follicular thyroid cancer who received 3.7 GBq (100 mCi) RAI were enrolled in this prospective hospital-based study. The enrolled patients were asked to place a thermoluminescent dosimeter in the living room, bedroom, and bathroom of their houses for 4 weeks to measure radiation exposure to the household environment...
September 2017: Medicine (Baltimore)
Leah H Rubin, Judith A Cook, Gayle Springer, Kathleen M Weber, Mardge H Cohen, Eileen M Martin, Victor G Valcour, Lorie Benning, Christine Alden, Joel Milam, Kathryn Anastos, Mary A Young, Deborah R Gustafson, Erin E Sundermann, Pauline M Maki
OBJECTIVE: Psychological risk factors (PRFs) are associated with impaired learning and memory in HIV-infected (HIV+) women. We determined the dynamic nature of the effects of PRFs and HIV serostatus on learning and memory over time. DESIGN: Multi-center, prospective cohort study METHODS:: Every two years between 2009 and 2013 (3 times), 646 HIV+ and 300 demographically-similar HIV-uninfected (HIV-) women from the Women's Interagency HIV Study completed neuropsychological (NP) testing and questionnaires measuring PRFs (perceived stress, post-traumatic stress disorder (PTSD) symptoms, depressive symptoms)...
August 28, 2017: AIDS
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