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https://www.readbyqxmd.com/read/28088681/maintenance-effects-of-working-memory-intervention-cogmed-in-children-with-symptomatic-epilepsy
#1
Amanda Fuentes, Elizabeth N Kerr
PURPOSE: To extend previous research documenting the benefits of working memory (WM) intervention (Cogmed) immediately post-intervention in children with epilepsy by assessing the 3-month maintenance effects. METHODS: Participants involved in a previous randomized clinical trial (RCT) were invited to participate if they completed Cogmed within the last 3months (n=15) and additional participants (n=13) were prospectively recruited. Standardized assessments of near-transfer effects (i...
January 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28087317/acute-otitis-media-caused-by-streptococcus-pneumoniae-serotype-19a-st320-clone-epidemiological-and-clinical-characteristics
#2
Hsin Chi, Nan-Chang Chiu, Fu-Yuan Huang, Chyong-Hsin Hsu, Kuo-Sheng Lee, Li-Min Huang, Yu-Chia Hsieh
BACKGROUND: Streptococcus pneumoniae serotype 19A ST320, a highly multiresistant and virulent clone, has emerged as a common pathogen causing acute otitis media (AOM) in children. METHODS: Patients aged 0-18 years with AOM who presented at Mackay Memorial Hospital, Taipei, Taiwan were prospectively enrolled between December 1, 2009, and November 30, 2012. For each patient, a specimen of middle-ear fluid was obtained and cultured. S. pneumoniae isolates were tested by serotyping, antibiotic-resistance profiling, and multilocus sequence typing...
December 19, 2016: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28080964/prospective-memory-mediated-by-interoceptive-accuracy-a-psychophysiological-approach
#3
Satoshi Umeda, Saiko Tochizawa, Midori Shibata, Yuri Terasawa
Previous studies on prospective memory (PM), defined as memory for future intentions, suggest that psychological stress enhances successful PM retrieval. However, the mechanisms underlying this notion remain poorly understood. We hypothesized that PM retrieval is achieved through interaction with autonomic nervous activity, which is mediated by the individual accuracy of interoceptive awareness, as measured by the heartbeat detection task. In this study, the relationship between cardiac reactivity and retrieval of delayed intentions was evaluated using the event-based PM task...
November 19, 2016: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28080117/effects-of-learned-episodic-event-structure-on-prospective-duration-judgments
#4
Myrthe Faber, Silvia P Gennari
The field of psychology of time has typically distinguished between prospective timing and retrospective duration estimation: in prospective timing, participants attend to and encode time, whereas in retrospective estimation, estimates are based on the memory of what happened. Prior research on prospective timing has primarily focused on attentional mechanisms to explain timing behavior, but it remains unclear the extent to which memory processes may also play a role. The present studies investigate this issue, and specifically, the role of newly learned encoded event structure...
January 12, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/28069918/posterior-alpha-eeg-dynamics-dissociate-current-from-future-goals-in-working-memory-guided-visual-search
#5
Ingmar E J de Vries, Joram van Driel, Christian N L Olivers
: Current models of visual search assume that search is guided by an active visual working memory representation of what we are currently looking for. This attentional template for currently relevant stimuli can be dissociated from accessory memory representations that are only needed prospectively, for a future task, and that should be prevented from guiding current attention. However, it remains unclear what electrophysiological mechanisms dissociate currently relevant (serving upcoming selection) from prospectively relevant memories (serving future selection)...
January 9, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28069097/cognitive-outcome-in-childhood-onset-epilepsy-a-five-decade-prospective-cohort-study
#6
Mira Karrasch, Petri Tiitta, Bruce Hermann, Juho Joutsa, Shlomo Shinnar, Juha Rinne, Anu Anttinen, Matti Sillanpää
OBJECTIVES: Little is known about the very long-term cognitive outcome in patients with childhood-onset epilepsy. The aim of this unique prospective population-based cohort study was to examine cognitive outcomes in aging participants with childhood-onset epilepsy (mean onset age=5.3 years) five decades later (mean age at follow-up=56.5 years). METHODS: The sample consisted of 48 participants with childhood-onset epilepsy and 48 age-matched healthy controls aged 48-63 years...
January 10, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28067736/alzheimer-s-disease-and-exercise-a-literature-review
#7
Shane P Cass
Alzheimer's disease (AD) is a progressive neurodegenerative disease that impairs memory and cognitive judgment. It is the leading cause of dementia in late adult life and is associated with a significant social burden and increased morbidity and mortality in the elderly. Because of mixed effectiveness of medications, exercise has been considered as a treatment for pre-clinical AD, late stage AD, and as a prevention strategy. Exercise appears to improve brain blood flow, increase hippocampal volume, and improve neurogenesis...
January 2017: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/28063853/reaction-time-and-postural-sway-modify-the-effect-of-executive-function-on-risk-of-falls-in-older-people-with-mild-to-moderate-cognitive-impairment
#8
Morag E Taylor, Stephen R Lord, Kim Delbaere, Susan E Kurrle, A Stefanie Mikolaizak, Jacqueline C T Close
OBJECTIVES: To explore the relationship between cognitive performance and falls in older people with mild to moderate cognitive impairment (CI) by investigating the mediational effects of medical, medication, neuropsychological, and physiological factors. DESIGN: Secondary analysis, prospective cohort study. SETTING: Community and low-level care. PARTICIPANTS: 177 older people (aged 82 ± 7 years) with mild to moderate CI (MMSE 11-23; ACE-R < 83)...
October 25, 2016: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28063694/post-wbrt-cognitive-impairment-and-hippocampal-neuronal-depletion-measured-by-in-vivo-metabolic-mr-spectroscopy-results-of-prospective-investigational-study
#9
Petr Pospisil, Tomas Kazda, Ludmila Hynkova, Martin Bulik, Marie Dobiaskova, Petr Burkon, Nadia N Laack, Pavel Slampa, Radim Jancalek
BACKGROUND AND PURPOSE: The aim of this prospective study is to evaluate post-whole brain radiotherapy (WBRT) changes in hippocampal concentration of N-acetylaspartate (h-tNAA) as a marker of neuronal loss and to correlate those changes to neurocognitive function. MATERIAL AND METHODS: Thirty-five patients with brain metastases underwent baseline single slice multi-voxel MR spectroscopy (MRS) examination for measurement of hippocampal h-tNAA together with baseline battery of neurocognitive tests focused on memory (Auditory Verbal Learning Test and Brief Visuospatial Memory Test - Revised) as well as quality of life questionnaires (EORTC QLQ-C30 a EORTC QLQ-BN20)...
January 4, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28061418/memory-and-mood-outcomes-after-anterior-thalamic-stimulation-for-refractory-partial-epilepsy
#10
Alexander I Tröster, Kimford J Meador, Christopher P Irwin, Robert S Fisher
PURPOSE: Bilateral deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) reduces seizures and is relatively safe but may be accompanied by complaints of memory problems and depression. This study examined incidence of memory and depression adverse events (AE) in the SANTE study blinded phase and their relationship to objective neurobehavioral measures, baseline characteristics, quality of life and long-term neurobehavioral outcome. METHOD: The neurobehavioral AE and neuropsychological data from a previously reported prospective randomized trial (SANTE) were analyzed...
December 23, 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28058833/de-novo-discovery-of-hdabco-bf4-molecular-ferroelectric-thin-film-for-non-volatile-low-voltage-memories
#11
Ping-Ping Shi, Yuan-Yuan Tang, Peng-Fei Li, Heng-Yun Ye, Ren-Gen Xiong
To date, the field of ferroelectric random access memories (FeRAMs) is mainly dominated by inorganic ferroelectric thin films like Pb(Zr,Ti)O3, which suffer from the issues of environmental harmfulness, high processing temperatures and high fabrication costs. In these respects, molecular ferroelectric thin films are particularly advantageous and thus become promis-ing alternatives to the conventional inorganic ones. For the prospect of FeRAMs applications, they should fulfill the require-ments of effective polarization switching and low-voltage, high-speed operation...
January 6, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28057075/the-efficacy-of-prospective-memory-rehabilitation-plus-metacognitive-skills-training-for-adults-with-traumatic-brain-injury-study-protocol-for-a-randomized-controlled-trial
#12
Jennifer Fleming, Tamara Ownsworth, Emmah Doig, Lauren Hutton, Janelle Griffin, Melissa Kendall, David H K Shum
BACKGROUND: Impairment of prospective memory (PM) is common following traumatic brain injury (TBI) and negatively impacts on independent living. Compensatory approaches to PM rehabilitation have been found to minimize the impact of PM impairment in adults with TBI; however, poor self-awareness after TBI poses a major barrier to the generalization of compensatory strategies in daily life. Metacognitive skills training (MST) is a cognitive rehabilitation approach that aims to facilitate the development of self-awareness in adults with TBI...
January 5, 2017: Trials
https://www.readbyqxmd.com/read/28052788/effet-paradoxal-du-vieillissement-sur-des-t%C3%A3-ches-de-m%C3%A3-moire-prospective-time-based-en-situation-de-laboratoire-et-en-milieu-naturel-r%C3%A3-le-des-fonctions-ex%C3%A3-cutives
#13
Barbara Azzopardi, Caroline Auffray, Christophe Kermarrec
The current study investigates the specific role of three executive functions in the explanation of performance variability on laboratory and naturalistic time-based prospective memory tasks in aging. Ninety people aged 18 to 80 years performed three executive tasks assessing inhibition, flexibility and updating, one laboratory time-based task and one naturalistic time-based task. The results indicate that age has a negative impact on the laboratory time-based task and a positive impact on the naturalistic task...
January 5, 2017: Canadian Journal on Aging, la Revue Canadienne du Vieillissement
https://www.readbyqxmd.com/read/28042986/association-between-mastication-and-cognitive-status-a-systematic-review
#14
REVIEW
Akio Tada, Hiroko Miura
PURPOSE: A substantial number of elderly people suffer from cognitive impairment and dementia, which are considered to have various risk factors, including masticatory dysfunction; however, the association between mastication and cognition is inconclusive. The objectives of this systematic review were to provide an overview of the literature on (1) the association between mastication and cognitive function and (2) the association between mastication and dementia incidence, in elderly people...
December 14, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28041314/spinal-stereotactic-body-radiotherapy-following-intralesional-curettage-with-separation-surgery-for-initial-or-salvage-chordoma-treatment
#15
Dennis T Lockney, Timothy Shub, Benjamin Hopkins, Natalie A Lockney, Nelson Moussazadeh, Eric Lis, Yoshiya Yamada, Adam M Schmitt, Daniel S Higginson, Ilya Laufer, Mark Bilsky
OBJECTIVE Chordoma is a rare malignant tumor for which en bloc resection with wide margins is advocated as primary treatment. Unfortunately, due to anatomical constraints, en bloc resection to achieve wide or marginal margins is not feasible for many patients as the resulting morbidity would be prohibitive. The objective of this study was to evaluate the efficacy of intralesional curettage and separation surgery followed by spinal stereotactic body radiation therapy (SBRT) in patients with chordomas in the mobile spine...
January 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28040430/association-of-obstructive-sleep-apnea-with-episodic-memory-and-cerebral-microvascular-pathology-a-preliminary-study
#16
Nancy A Kerner, Steven P Roose, Gregory H Pelton, Adam Ciarleglio, Jennifer Scodes, Cody Lentz, Joel R Sneed, D P Devanand
OBJECTIVES: To evaluate the impact of obstructive sleep apnea (OSA) on neurocognitive function and brain morphology in older adults with depression and cognitive impairment. METHODS: We prospectively screened OSA with the STOP-Bang questionnaire in the last 25 patients enrolled into the Donepezil Treatment of Cognitive Impairment and Depression (DOTCODE) trial. High and low probability of OSA were defined as a STOP-Bang score of ≥5 (h-OSA) and of <5 (l-OSA), respectively...
November 17, 2016: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28036212/ultranarrow-optical-inhomogeneous-linewidth-in-a-stoichiometric-rare-earth-crystal
#17
R L Ahlefeldt, M R Hush, M J Sellars
We obtain a low optical inhomogeneous linewidth of 25 MHz in the stoichiometric rare-earth crystal EuCl_{3}·6H_{2}O by isotopically purifying the crystal in ^{35}Cl. With this linewidth, an important limit for stoichiometric rare-earth crystals is surpassed: the hyperfine structure of ^{153}Eu is spectrally resolved, allowing the whole population of ^{153}Eu^{3+} ions to be prepared in the same hyperfine state using hole-burning techniques. This material also has a very high optical density, and can have long coherence times when deuterated...
December 16, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/28034886/sustained-antibody-responses-six-years-following-one-two-or-three-doses-of-quadrivalent-hpv-vaccine-in-adolescent-fijian-girls-and-subsequent-responses-to-a-single-dose-of-bivalent-hpv-vaccine-a-prospective-cohort-study
#18
Zheng Quan Toh, Fiona M Russell, Rita Reyburn, James Fong, Evelyn Tuivaga, Tupou Ratu, Cattram D Nguyen, Rachel Devi, Mike Kama, Silivia Matanitobua, Sepehr N Tabrizi, Suzanne M Garland, Rohit Sinha, Ian Frazer, Lisi Tikoduadua, Joseph Kado, Eric Rafai, Edward K Mulholland, Paul V Licciardi
BACKGROUND: The antibody response following reduced HPV vaccine doses has not been determined. We compared the antibody responses in girls previously vaccinated with zero, one, two or three doses of 4vHPV (Gardasil(®),Merck Inc.) six years previously. METHODS: A prospective cohort study was undertaken in 200 Fijian girls (15-19 years old). Approximately equal numbers of girls from two main ethnic groups (Fijians-of-Indian-Descent;FIDs) and (Indigenous-Fijians;iTaukei) in Fiji were recruited for each dosage groups...
December 28, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28033681/high-endothelial-venules-associated-with-t-cell-subsets-in-the-inflamed-gut-of-newly-diagnosed-inflammatory-bowel-disease-patients
#19
Carmen S Horjus Talabur Horje, Carolijn Smids, Jos W R Meijer, Marcel J Groenen, Maaike K Rijnders, Ellen G van Lochem, Peter J Wahab
BACKGROUND: Naive and central memory T lymphocytes (TN and TCM ) can infiltrate the inflamed gut mucosa in Inflammatory Bowel Disease (IBD) patients. Homing of these subsets to the gut might be explained by ectopic formation of tertiary lymphoid organs (TLOs), containing high endothelial venules (HEVs). We aimed to evaluate the presence of HEVs and TLOs in inflamed intestinal mucosa of newly diagnosed, untreated, IBD patients in relation to the presence of TN and TCM lymphocytes. METHODS: IBD patients (n=39) and healthy controls (n=8) were prospectively included...
December 29, 2016: Clinical and Experimental Immunology
https://www.readbyqxmd.com/read/28032183/a-prospective-case-control-study-of-functional-outcomes-and-related-quality-of-life-after-colectomy-for-neoplasia
#20
Adela Brigic, Samia Sakuma, Richard E Lovegrove, Paul Bassett, Omar Faiz, Susan K Clark, Neil Mortensen, Robin H Kennedy
AIM: Our aim was to assess bowel function and its effect on overall quality of life (QOL) when compared to healthy controls after colectomy. METHODS: Patients undergoing resection of colorectal neoplasia were recruited pre-operatively and followed up at 6 and 12 months, to assess 'early' bowel function. Patients who underwent surgery 2 to 4 years previously were recruited for assessment of 'intermediate' bowel function. Healthy relatives were recruited as controls...
December 28, 2016: International Journal of Colorectal Disease
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