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https://www.readbyqxmd.com/read/28227297/features-of-cerebral-oxygenation-detects-brain-injury-in-premature-infants
#1
John M O'Toole, Mmoloki Kenosi, Daragh Finn, Geraldine B Boylan, Eugene M Dempsey, John M O'Toole, Mmoloki Kenosi, Daragh Finn, Geraldine B Boylan, Eugene M Dempsey, Daragh Finn, Eugene M Dempsey, Mmoloki Kenosi, John M Otoole, Geraldine B Boylan
Babies born prematurely can develop brain injury within days after birth. Early identification of high-risk infants enables appropriate clinical care to mitigate potential lifelong disabilities. Near infra-red spectroscopy is an established technology that can provide continuous measurements of cerebral oxygen saturation (rcSO2) over this critical period. We develop a feature set of the rcSO2 signal for the purpose of detecting brain injury. Our feature set contains amplitude, spectral, and fractal dimension features within 5 frequency bands...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226028/late-preterm-infants-motor-development-until-term-age
#2
Viviane Martins Santos, Cibelle Kayenne Martins Roberto Formiga, Paulo Roberto Bezerra de Mello, Cléa Rodrigues Leone
OBJECTIVES: To analyze the motor development of late preterm newborn infants (LPI) from birth to term-corrected age using the Test of Infant Motor Performance (TIMP) and to compare the obtained results with those of term infants at birth. METHODS: Prospective cohort study, 29 late preterm newborn infants were evaluated by the TIMP at birth and every two weeks until term-corrected age. The TIMP was administered to 88 term infants at birth. RESULTS: The mean TIMP score of late preterm newborn infants was 51...
January 1, 2017: Clinics
https://www.readbyqxmd.com/read/28225789/non-melanoma-skin-cancer-and-risk-of-alzheimer-s-disease-and-all-cause-dementia
#3
Sigrun A J Schmidt, Anne G Ording, Erzsébet Horváth-Puhó, Henrik T Sørensen, Victor W Henderson
Cancer patients may be at decreased risk of Alzheimer's disease. This hypothesis is best developed for non-melanoma skin cancer (NMSC), but supportive epidemiological data are sparse. We therefore conducted a nationwide cohort study of the association between NMSC and Alzheimer's disease (main outcome) and all-cause dementia. Using Danish medical databases, we identified adults diagnosed with NMSC between 1 January 1980 and 30 November 2013 (n = 216,221) and a comparison cohort of five individuals matched to each NMSC patient by sex and birth year (n = 1,081,097)...
2017: PloS One
https://www.readbyqxmd.com/read/28224092/language-and-cognitive-outcome-for-high-risk-neonates-at-the-age-of-2-3-years-experience-from-an-arab-country
#4
Tamer Abou-Elsaad, Hesham Abdel-Hady, Hemmat Baz, Doaa ElShabrawi
AIM: To investigate the effect of different neonatal risk factors on different language parameters as well as cognitive abilities among Arabic speaking Egyptian children at the age of two to three years of life and to find out which risk factor(s) had the greatest impact on language and cognitive abilities. METHODS: This retrospective cohort study was conducted on 103 children with age range of 2-3 years (median age 31 mo). They were 62 males and 41 females who were exposed to different high-risk factors in the perinatal period, with exclusion of metabolic disorders, sepsis/meningitis, congenital anomalies and chromosomal aberrations...
February 8, 2017: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/28223732/effects-of-sex-and-generation-on-hepatitis-b-viral-load-in-families-with-hepatocellular-carcinoma
#5
Ai-Ru Hsieh, Cathy Sj Fann, Chau-Ting Yeh, Hung-Chun Lin, Shy-Yi Wan, Yi-Cheng Chen, Chia-Lin Hsu, Jennifer Tai, Shi-Ming Lin, Dar-In Tai
AIM: To explore factors associated with persistent hepatitis B virus (HBV) infection in a cohort of hepatocellular carcinoma (HCC)-affected families and then investigate factors that correlate with individual viral load among hepatitis B surface antigen (HBsAg)-positive relatives. METHODS: We evaluated non-genetic factors associated with HBV replication in relatives of patients with HCC. Relatives of 355 HCC cases were interviewed using a structured questionnaire...
February 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28223371/socioeconomic-attainment-of-extremely-low-birth-weight-survivors-the-role-of-early-cognition
#6
Kathleen G Dobson, Mark A Ferro, Michael H Boyle, Louis A Schmidt, Saroj Saigal, Ryan J Van Lieshout
OBJECTIVES: To determine: (1) if childhood cognitive and academic abilities mediate the association between being born at extremely low birth weight (ELBW) and socioeconomic attainment at age 29 to 36 years; (2) which cognitive abilities (IQ, verbal abilities, fluid intelligence, mathematical abilities, or academic achievement) most strongly mediate this association; and (3) if the mediating role of cognition is different in ELBW survivors with significant neurosensory impairment (NSI)...
February 21, 2017: Pediatrics
https://www.readbyqxmd.com/read/28223174/increasing-mumps-incidence-rates-among-children-and-adolescents-in-the-republic-of-korea-age-period-cohort-analysis
#7
Young-June Choe, Young Hwa Lee, Sung-Il Cho
BACKGROUND: To characterize the temporal dynamics of mumps epidemiology according to different vaccine strains used, we decomposed gender-specific trends in an age-period-cohort (APC) analysis for mumps cases reported in South Korea. METHODS: We used the national surveillance data to describe the epidemiology of mumps cases from 2001 to 2015. An APC model was used to break down the reported mumps cases into the effects of age, period, and birth cohort. RESULTS: From 2001 to 2015, the incidence started to increase from fewer than 10 cases to more than 100 cases per 100,000...
February 18, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28223163/17-alpha-hydroxyprogesterone-caproate-did-not-reduce-the-rate-of-recurrent-preterm-birth-in-a-prospective-cohort-study
#8
David B Nelson, Donald D McIntire, Jeffrey McDonald, John Gard, Paula Turrichi, Kenneth J Leveno
BACKGROUND: 17-alpha hydroxyprogesterone caproate for prevention of recurrent preterm birth is recommended for use in the United States. OBJECTIVE: To assess the clinical effectiveness of 17-alpha hydroxyprogesterone caproate to prevent recurrent preterm birth ≤ 35 weeks compared to similar births in our obstetric population prior to the implementation of 17-alpha hydroxyprogesterone caproate. STUDY DESIGN: This was a prospective cohort study of 17-alpha hydroxyprogesterone caproate in our obstetric population...
February 18, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28222962/safety-of-parenteral-nutrition-in-newborns-results-from-a-nationwide-prospective-cohort-study
#9
Alexandre Lapillonne, Marie-Pierre Berleur, Yvette Brasseur, Sophie Calvez
BACKGROUND & AIMS: Limited or delayed availability of parenteral nutrition (PN) solutions, as well as difficulties in ordering are often identified as reasons for non-compliance with international guidelines in newborns. This study aims at assessing the modality of use and safety of premixed standardized PN solutions in a nationwide prospective cohort of newborns treated in clinical practice. METHODS: Two premixed fixed formulations with respective osmolarity of 715 and 790 mOsm/L specifically designed for neonates were made available throughout the country for clinical use from birth onwards...
February 8, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28222824/curiosity-killed-the-cat-no-evidence-of-an-association-between-cat-ownership-and-psychotic-symptoms-at-ages-13-and-18-years-in-a-uk-general-population-cohort
#10
F Solmi, J F Hayes, G Lewis, J B Kirkbride
BACKGROUND: Congenital or early life infection with Toxoplasma gondii has been implicated in schizophrenia aetiology. Childhood cat ownership has been hypothesized as an intermediary marker of T. gondii infection and, by proxy, as a risk factor for later psychosis. Evidence supporting this hypothesis is, however, limited. METHOD: We used birth cohort data from the Avon Longitudinal Study of Parents and Children (ALSPAC) to investigate whether cat ownership in pregnancy and childhood (ages 4 and 10 years) was associated with psychotic experiences (PEs) in early (age 13, N = 6705) and late (age 18, N = 4676) adolescence, rated from semi-structured interviews...
February 22, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28222704/duration-of-second-stage-of-labor-and-instrumental-delivery-as-risk-factors-for-severe-perineal-lacerations-population-based-study
#11
Marija Simic, Sven Cnattingius, Gunnar Petersson, Anna Sandström, Olof Stephansson
BACKGROUND: We sought to investigate the impact of the duration of second stage of labor on risk of severe perineal lacerations (third and fourth degree). METHODS: This population based cohort study was conducted in the Stockholm/Gotland region, Sweden, 2008-2014. Study population included 52 211 primiparous women undergoing vaginal delivery with cephalic presentation at term. Unconditional logistic regression analysis was used to calculate crude and adjusted odds ratios (OR), using 95% confidence intervals (CI)...
February 21, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28222431/the-routine-use-of-intrapartum-ultrasound-in-clinical-decision-making-during-the-second-stage-of-labor-does-it-have-any-impact-on-delivery-outcomes
#12
Oren Barak, Roni Levy, Orna Flidel, Svetlana Zaks, Moshe Gillor, Zion Hagay, Edi Vaisbuch
BACKGROUND/AIMS: The study aimed to assess whether the use of intrapartum transperineal ultrasound (US) can reduce the rate of failed vacuum extraction (VE). METHODS: This is a retrospective cohort study including all women delivering at term with the diagnosis of protracted second stage of labor. The mode of delivery and rate of failed VE were compared between women who underwent a US examination prior to the decision on obstetrical interventions ("+US" group) and those in whom clinical decisions were based upon digital assessment only ("no-US" group)...
February 22, 2017: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/28222232/dietary-total-antioxidant-capacity-in-early-school-age-and-subsequent-allergic-disease
#13
Anna Gref, Susanne Rautiainen, Olena Gruzieva, Niclas Håkansson, Inger Kull, Göran Pershagen, Magnus Wickman, Alicja Wolk, Erik Melén, Anna Bergström
BACKGROUND: Dietary antioxidant intake has been hypothesized to influence the development of allergic diseases, however, few prospective studies have investigated this association. OBJECTIVE: Our aim was to study the association between total antioxidant capacity (TAC) of the diet at age 8 years and the subsequent development of asthma, rhinitis and sensitization to inhalant allergens between 8 and 16 years, and to assess potential effect modification by known risk factors...
February 21, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28222095/delays-and-loss-to-follow-up-before-treatment-of-drug-resistant-tuberculosis-following-implementation-of-xpert-mtb-rif-in-south-africa-a-retrospective-cohort-study
#14
Helen Cox, Lindy Dickson-Hall, Norbert Ndjeka, Anja Van't Hoog, Alison Grant, Frank Cobelens, Wendy Stevens, Mark Nicol
BACKGROUND: South Africa has a large burden of rifampicin-resistant tuberculosis (RR-TB), with 18,734 patients diagnosed in 2014. The number of diagnosed patients has increased substantially with the introduction of the Xpert MTB/RIF test, used for tuberculosis (TB) diagnosis for all patients with presumptive TB. Routine aggregate data suggest a large treatment gap (pre-treatment loss to follow-up) between the numbers of patients with laboratory-confirmed RR-TB and those reported to have started second-line treatment...
February 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28221733/regional-lung-ventilation-pattern-in-preschool-children-with-bronchopulmonary-dysplasia-is-modified-by-bronchodilator-response
#15
Wojciech Durlak, Małgorzata Klimek, Przemko Kwinta
BACKGROUND: Bronchopulmonary dysplasia (BPD) remains a significant long-term complication of prematurity. A standardized method of pulmonary function testing is still not available in preschool children with BPD. We investigated the feasibility of Electrical Impedance Segmentography (EIS) monitoring in this group and the impact of bronchodilator response (BDR) to salbutamol on the pattern of lung ventilation. METHODS: We conducted a follow-up study of 4-year-old premature children who had been treated in the tertiary NICU...
March 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28221677/cardiovascular-disease-in-relation-to-placental-abruption-a%C3%A2-population-based-cohort-study-from-denmark
#16
Cande V Ananth, Anne Vinkel Hansen, Michelle A Williams, Anne-Marie Nybo Andersen
BACKGROUND: Cardiovascular (CVD) complications stemming from vascular dysfunction have been widely explored in the setting of preeclampsia. However, the impact of abruption, a strong indicator of microvascular disturbance, on the risk of CVD mortality and morbidity remains poorly characterised. METHODS: We designed a cohort analysis of 828 289 women who delivered singletons in Denmark between 1978 and 2010. We linked the National Patient Registry and the Registry of Causes of Death to the Danish Birth Registry to ascertain CVD events...
February 21, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28220215/postpartum-depression-risk-factors-among-recent-refugee-asylum-seeking-non-refugee-immigrant-and-canadian-born-women-results-from-a-prospective-cohort-study
#17
Cindy-Lee Dennis, Lisa Merry, Anita J Gagnon
PURPOSE: The objective was to examine and compare risk factors for postpartum depression among: (1) recent (≤5 years) migrant and Canadian-born women, and (2) refugee, asylum-seeking, and non-refugee immigrant women. METHODS: A sample of 1536 women (1024 migrant and 512 Canadian-born) were recruited from 12 hospitals. Women completed questionnaires at 1-2 and 16 weeks postpartum including questions on socio-demographics, biomedical history, health services, and migration and resettlement factors...
February 20, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28220213/labour-market-marginalisation-subsequent-to-suicide-attempt-in-young-migrants-and-native-swedes
#18
T Niederkrotenthaler, M Wang, M Helgesson, H Wilcox, M Gould, E Mittendorfer-Rutz
PURPOSE: This study aimed to compare young individuals who differed in terms of birth region and history of suicide attempt regarding socio-demographic and healthcare factors, and with regard to their risks of subsequent unemployment, sickness absence and disability pension. METHODS: Prospective cohort study based on register linkage of 2,801,558 Swedish residents, aged 16-40 years in 2004, without disability pension and with known birth country, followed up 2005-2011...
February 20, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28219408/the-impact-of-post-operative-sepsis-on-mortality-after-hospital-discharge-among-elective-surgical-patients-a-population-based-cohort-study
#19
Lixin Ou, Jack Chen, Ken Hillman, Arthas Flabouris, Michael Parr, Hassan Assareh, Rinaldo Bellomo
BACKGROUND: Our aim in the present study was to assess the mortality impact of hospital-acquired post-operative sepsis up to 1 year after hospital discharge among adult non-short-stay elective surgical patients. METHODS: We conducted a population-based, retrospective cohort study of all elective surgical patients admitted to 82 public acute hospitals between 1 January 2007 and 31 December 2012 in New South Wales, Australia. All adult elective surgical admission patients who stayed in hospital for ≥4 days and survived to discharge after post-operative sepsis were identified using the Admitted Patient Data Collection records linked with the Registry of Births, Deaths, and Marriages...
February 20, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28219025/mortality-in-individuals-with-disruptive-behavior-disorders-diagnosed-by-specialist-services-a-nationwide-cohort-study
#20
James G Scott, Marianne Giørtz Pedersen, Holly E Erskine, Aida Bikic, Ditte Demontis, John J McGrath, Søren Dalsgaard
Disruptive behavior disorders (DBDs), inclusive of oppositional defiant disorder (ODD) and conduct disorder (CD), are associated with outcomes likely to increase risk of mortality. Using Danish National Registers, a total of 1.92 million individuals including 9495 individuals with DBDs diagnosed by specialist services were followed from their first birthday to 2013. Those with and without DBDs were compared using mortality rate ratios (MRRs) estimated using Poisson regression and adjusted for calendar period, age, sex, family history of psychiatric disorders, maternal age at time of birth, paternal age at time of birth, parental education status, and parental employment status...
February 13, 2017: Psychiatry Research
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