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https://www.readbyqxmd.com/read/29666141/examining-the-effectiveness-of-consuming-flour-made-from-agronomically-biofortified-wheat-zincol-2016-nr-421-for-improving-zn-status-in-women-in-a-low-resource-setting-in-pakistan-study-protocol-for-a-randomised-double-blind-controlled-cross-over-trial-bizifed
#1
Nicola M Lowe, Muhammad Jaffar Khan, Martin R Broadley, Munir H Zia, Harry J McArdle, Edward J M Joy, Heather Ohly, Babar Shahzad, Ubaid Ullah, Gul Kabana, Rashid Medhi, Mukhtiar Zaman Afridi
INTRODUCTION: Dietary zinc (Zn) deficiency is a global problem, particularly in low-income and middle-income countries where access to rich, animal-source foods of Zn is limited due to poverty. In Pakistan, Zn deficiency affects over 40% of the adult female population, resulting in suboptimal immune status and increased likelihood of complications during pregnancy. METHODS AND ANALYSIS: We are conducting a double-blind, randomised controlled feeding study with cross-over design in a low-resource setting in Pakistan...
April 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29658370/changes-in-endothelial-function-arterial-stiffness-and-blood-pressure-in-pregnant-women-after-consumption-of-high-flavanol-and-high-theobromine-chocolate-a-double-blind-randomized-clinical-trial
#2
Asma Babar, Emmanuel Bujold, Vicky Leblanc, Élise Lavoie-Lebel, Joalee Paquette, Laurent Bazinet, Simone Lemieux, Isabelle Marc, Belkacem Abdous, Sylvie Dodin
OBJECTIVES: The aim of this 2-group, parallel, double blind single-centre RCT was to evaluate the acute and chronic impacts of high flavanol high theobromine (HFHT) chocolate consumption on endothelial function, arterial stiffness and blood pressure (BP) in women at risk of preeclampsia. METHODS: 131 pregnant women considered at risk of preeclampsia based on uterine artery Doppler ultrasound were divided into two groups (HFHT or low flavanol and theobromine chocolate (LFLT)...
April 16, 2018: Hypertension in Pregnancy
https://www.readbyqxmd.com/read/29651337/weaving-the-health-and-pharmaceutical-care-agenda-through-the-themes-of-the-commonwealth-heads-of-government-meeting-chogm-london-2018
#3
EDITORIAL
Victoria Rutter, Amy Hai Yan Chan, Chloe Tuck, Lina Bader, Zaheer-Ud-Din Babar, Ian Bates
The biennial Commonwealth Heads of Government Meeting (CHOGM) this year is based around four key themes: prosperity, fairness, sustainability and security. This is an opportune time to consider the role of pharmacists in healthcare delivery, and particularly their contribution to achieving the United Nations Sustainable Development Goals (SDGs). As a member of the Commonwealth Health Professions Alliance (CHPA), the Commonwealth Pharmacists Association (CPA) has been working to ensure that pharmacy-related aspects of health are represented in the advocacy papers submitted by Civil Society...
2018: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/29645024/f-doped-carbon-nano-onion-films-as-scaffold-for-highly-efficient-and-stable-li-metal-anodes-a-novel-laser-direct-write-process
#4
Dhanya Puthusseri, Malik Wahid, Aniruddha Basu, Rohit Babar, Mukul Kabir, Satishchandra Ogale
Li metal is the most promising choice for anode in high-energy rechargeable batteries, but the dendrite growth upon cycling leads to safety concerns and poor cycle life. Herein, we demonstrate a novel and scalable approach for direct writing of a thin layer of carbon nano-onions on copper substrate to stabilize the Li metal anode and prevent the dendrite growth. The F-doped carbon nano-onion film (F-CNOF) scaffold enables reversible electroplating for over 1500 hours (300 cycles) with a coulombic efficiency of ∼100%...
April 12, 2018: Nanoscale
https://www.readbyqxmd.com/read/29642720/use-of-potentially-inappropriate-medications-in-people-with-dementia-in-vietnam-and-its-associated-factors
#5
Tuan Anh Nguyen, Thang Pham, Huyen Thi Thanh Vu, Thanh Xuan Nguyen, Trinh Thi Vu, Binh Thi Thanh Nguyen, Ngoc Quynh Nguyen, Binh Thanh Nguyen, Binh Thanh Nguyen, Tam Ngoc Nguyen, Sinh Viet Phan, Anh Trung Nguyen, Tuan Le Pham, Ha Thu Dang, Lisa Kalisch-Ellett, Marianne Gillam, Nicole Pratt, Sun Qiang, Haipeng Wang, Tipaporn Kanjanarach, Mohamed Azmi Ahmad Hassali, Zaheer-Ud-Din Babar, Asrenee Ab Razak, Dujrudee Chinwong, Elizabeth E Roughead
This study examined the use of potentially inappropriate medicines that may affect cognition (PIMcog) in people with dementia and its associated factors. Medical records of all outpatients with dementia attending a tertiary hospital in Vietnam between January 1, 2015, and December 31, 2016, were examined. Medicine use was assessed against a list of PIMcog. Variables associated with having a PIMcog were assessed using a multiple logistic regression. Of the 128 patients, 41% used a PIMcog, 39.1% used cholinesterase inhibitors (CEIs) concomitantly with anticholinergics, and 18% used antipsychotics...
January 1, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/29611352/impact-of-social-complexity-on-outcomes-in-cystic-fibrosis-after-transfer-to-adult-care
#6
Erin M Crowley, Gabriel T Bosslet, Babar Khan, Mary Ciccarelli, Cynthia D Brown
OBJECTIVE: This study evaluates the roles of medical and social complexity in health care use outcomes in cystic fibrosis (CF) after transfer from pediatric to adult care. METHODS: Retrospective cohort design included patients with CF who were transitioned into adult care at Indiana University from 2005 to 2015. Predictor variables included demographic and comorbidity data, age at transition, treatment complexity score (TCS), and an objective scoring measure of their social complexity (Bob's Level of Social Support, BLSS)...
April 2, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29610064/frontoethmoidal-encephalocele-report-of-a-case
#7
Angel Horcajadas, Antonio Palma, Babar M Khalon
Encephaloceles are uncommon in western countries and most cases are located in the occipital bone. Frontal encephaloceles may involve the ethmoid bone, nasal bones and/or the orbits. Surgical repair is complex and usually requires a multidisciplinary approach. The goal of the surgery is to reconstruct the normal anatomy, to achieve a good cosmetic repair and to avoid a cerebrospinal fluid leak. We present a case of a patient with a large congenital frontoethmoidal encephalocele. Autologous calvarian bone grafts were used to repair of encephalocele defect and for the reconstruction of the frontonasal area...
March 30, 2018: Neurocirugía
https://www.readbyqxmd.com/read/29580264/improving-recovery-and-outcomes-every-day-after-the-icu-improve-study-protocol-for-a-randomized-controlled-trial
#8
Sophia Wang, Jessica Hammes, Sikandar Khan, Sujuan Gao, Amanda Harrawood, Stephanie Martinez, Lyndsi Moser, Anthony Perkins, Frederick W Unverzagt, Daniel O Clark, Malaz Boustani, Babar Khan
BACKGROUND: Delirium affects nearly 70% of older adults hospitalized in the intensive care unit (ICU), and many of those will be left with persistent cognitive impairment or dementia. There are no effective and scalable recovery models to remediate ICU-acquired cognitive impairment and its attendant elevated risk for dementia or Alzheimer disease (AD). The Improving Recovery and Outcomes Every Day after the ICU (IMPROVE) trial is an ongoing clinical trial which evaluates the efficacy of a combined physical exercise and cognitive training on cognitive function among ICU survivors 50 years and older who experienced delirium during an ICU stay...
March 27, 2018: Trials
https://www.readbyqxmd.com/read/29572215/health-related-quality-of-life-in-congenital-heart-disease-surgery-in-children-and-young-adults-a-systematic-review-and-meta-analysis
#9
Laila Akbar Ladak, Babar Sultan Hasan, Janice Gullick, Robyn Gallagher
BACKGROUND: As survival improves in the congenital heart disease (CHD) population, health-related quality of life (HRQOL) outcomes become increasingly important. While surgery improves survival, poor HRQOL occurs postoperatively and cardiac-related HRQOL outcomes are rarely reported. OBJECTIVE: To conduct a systematic review and meta-analyses of general and cardiac-related HRQOL in CHD surgical children and young adults. METHOD: Medline, CINAHL and EMBASE were searched...
March 23, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29566743/electronic-cigarettes-use-and-perception-amongst-medical-students-a-cross-sectional-survey-from-sindh-pakistan
#10
Nousheen Iqbal, Zain A Khan, Syed Muhammad Hamza Anwar, Omar Irfan, Babar Irfan, Ammar Mushtaq, Maria Bibi, Faraz Siddiqui, Javaid A Khan
OBJECTIVE: The manufacturers of electronic cigarettes (e-cigarettes) are actively marketing their product through electronic and social media. Undergraduate medical students are expected to have better knowledge and awareness as they directly interact with patients in their training, The purpose of this study is therefore, to determine knowledge, use and perception regarding e-cigarettes among medical students from Sindh, Pakistan. RESULTS: A cross-sectional study was conducted between 1st July and 30th September 2016 at five different medical colleges situated in the second largest province of Sindh, Pakistan...
March 22, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29554157/mobile-medical-apps-for-patient-education-a-graded-review-of-available-dermatology-apps
#11
Aisha Masud, Shahram Shafi, Babar K Rao
The utilization of mobile applications (apps) as educational resources for patients highlights the need for an objective method of evaluating the quality of health care-related mobile apps. In this study, a quantified rubric was developed to objectively grade publicly available dermatology mobile apps with the primary focus of patient education. The rubric included 5 criteria thought to be most important in evaluating the adequacy of these apps in relaying health information to patients: educational objectives, content, accuracy, design, and conflict of interest...
February 2018: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29551418/combined-effect-of-sauna-bathing-and-cardiorespiratory-fitness-on-the-risk-of-sudden-cardiac-deaths-in-caucasian-men-a-long-term-prospective-cohort-study
#12
REVIEW
Jari A Laukkanen, Tanjaniina Laukkanen, Hassan Khan, Maira Babar, Setor K Kunutsor
Both cardiorespiratory fitness (CRF) and frequency of sauna bathing (FSB) are each strongly and independently associated with sudden cardiac death (SCD) risk. However, the combined effect of CRF and FSB on SCD risk has not been previously investigated. We evaluated the joint impact of CRF and FSB on the risk of SCD in the Kuopio Ischemic Heart Disease prospective cohort study of 2291 men aged 42-61 years at recruitment. Objectively measured CRF and self-reported sauna bathing habits were assessed at baseline...
March 15, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29543763/context-mining-of-sedentary-behaviour-for-promoting-self-awareness-using-a-smartphone
#13
Muhammad Fahim, Thar Baker, Asad Masood Khattak, Babar Shah, Saiqa Aleem, Francis Chow
Sedentary behaviour is increasing due to societal changes and is related to prolonged periods of sitting. There is sufficient evidence proving that sedentary behaviour has a negative impact on people's health and wellness. This paper presents our research findings on how to mine the temporal contexts of sedentary behaviour by utilizing the on-board sensors of a smartphone. We use the accelerometer sensor of the smartphone to recognize user situations (i.e., still or active). If our model confirms that the user context is still, then there is a high probability of being sedentary...
March 15, 2018: Sensors
https://www.readbyqxmd.com/read/29532945/uplc-hrms-based-untargeted-metabolic-profiling-reveals-changes-in-chickpea-cicer-arietinum-metabolome-following-long-term-drought-stress
#14
Naeem Khan, Asghari Bano, Mohammad Atikur Rahman, Bala Rathinasabapathi, Md Ali Babar
Genetic improvement for drought tolerance in chickpea requires a solid understanding of biochemical processes involved with different physiological mechanisms. The objective of this study is to demonstrate genetic variations in altered metabolic levels in chickpea varieties (tolerant and sensitive) grown under contrasting water regimes through UPLC-HRMS based untargeted metabolomic profiling. Chickpea plants were exposed to drought stress at the three-leaf stage for 25 days and the leaves were harvested at 14 days and 25 days after the imposition of drought stress...
March 13, 2018: Plant, Cell & Environment
https://www.readbyqxmd.com/read/29531422/leadership-action-learning-and-accountability-to-deliver-quality-care-for-women-newborns-and-children
#15
Abosede Adeniran, Andrew Likaka, Anneka Knutsson, Anthony Costello, Bernadette Daelmans, Blerta Maliqi, Daniel Burssa, Joseph Freer, Ian Askew, Lisa Bowen, Lily Kak, Lori McDougall, Nabila Zaka, Özge Tunçalp, Petra Tenhoope-Bender, Shamsuzzoha Babar Syed, Stefan Swartling Peterson, Thiago Luchesi, Willibald Zeck, Wilson Were, Pierre Barker, Zainab Naimy
No abstract text is available yet for this article.
March 1, 2018: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/29528387/antioxidant-effects-of-four-heartwood-extractives-on-midgut-enzyme-activity-in-heterotermes-indicola-blattodea-rhinotermitidae
#16
Babar Hassan, Sohail Ahmed, Grant Kirker, Mark E Mankowski, Muhammad Misbah-Ul-Haq
Heterotermes indicola (Wasmann) (Blattodea: Rhinotermitidae) is a species of subterranean termite that is a destructive pest of wood and wood products in Pakistan. This study evaluated the antioxidant and antienzyme potential of heartwood extractives against H. indicola. Heartwood extractives of four durable wood species, Tectona grandis (L.f), Dalbergia sissoo (Roxb.), Cedrus deodara (Roxb.), and Pinus roxburghii (Sarg.) were removed from wood shavings via soxhlet extraction with an ethanol:toluene solvent system...
March 8, 2018: Environmental Entomology
https://www.readbyqxmd.com/read/29511353/a-comprehensive-study-of-de-novo-genome-assemblers-current-challenges-and-future-prospective
#17
Abdul Rafay Khan, Muhammad Tariq Pervez, Masroor Ellahi Babar, Nasir Naveed, Muhammad Shoaib
Background: Current advancements in next-generation sequencing technology have made possible to sequence whole genome but assembling a large number of short sequence reads is still a big challenge. In this article, we present the comparative study of seven assemblers, namely, ABySS, Velvet, Edena, SGA, Ray, SSAKE, and Perga, using prokaryotic and eukaryotic paired-end as well as single-end data sets from Illumina platform. Results: Results showed that in case of single-end data sets, Velvet and ABySS outperformed in all the seven assemblers with comparatively low assembling time and high genome fraction...
2018: Evolutionary Bioinformatics Online
https://www.readbyqxmd.com/read/29492069/change-in-central-corneal-thickness-corneal-endothelial-cell-density-anterior-chamber-depth-and-axial-length-after-repair-of-rhegmatogenous-retinal-detachment
#18
Ahsan Mukhtar, Mohammad Asim Mehboob, Zaheer Uddin Babar, Mazhar Ishaq
Objective: To compare the effects of Pars Plana Vitrectomy (PPV) and Scleral Buckling (SB) with reference to Central Corneal Thickness (CCT), Corneal Endothelial-Cell Density (CED), Anterior Chamber Depth (ACD) and Axial Length (AL) in repair of Rhegmatogenous Retinal Detachment (RRD). Methods: This comparative cross sectional analytical study was conducted at Armed Forces Institute of Ophthalmology (AFIO), Rawalpindi from July 2013 to July 2015. A total of 69 eyes of 69 patients which underwent repair of RRD by either PPV or SB were analyzed to compare mean change in CCT, CED, ACD and AL between two groups...
November 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29492060/neutrophil-lymphocyte-ratio-nlr-a-well-assessment-tool-of-glycemic-control-in-type-2-diabetic-patients
#19
Mazhar Hussain, Muhammad Zafar Majeed Babar, Lubna Akhtar, Muhammad Shahbaz Hussain
Background and Objective: Increased neutrophil lymphocyte ratio (NLR) is a marker as well as predictor of various cardiac and non cardiac disorders. Our aim was to assess the relationship between NLR and different level of glycemic control in type 2 diabetic patients. Methods: An observational study was conducted at diabetic clinic of Sheikh Zayed Medical College/Hospital, Rahim Yar Khan from September 2016 to February 2017 in which 330 type 2 diabetic patients were randomly divided in to three groups based upon diabetes control according to ADA criteria...
November 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29472360/immobilized-fibrinogen-activates-human-platelets-through-gpvi
#20
Pierre H Mangin, Marie-Blanche Onselaer, Nicolas Receveur, Nicolas Le Lay, Alexander T Hardy, Clare Wilson, Ximena Sanchez, Stephane Loyau, Arnaud Dupuis, Amir K Babar, Jeanette Lc Miller, Helen Philippou, Craig E Hughes, Andrew B Herr, Robert As Ariëns, Diego Mezzano, Martine Jandrot-Perrus, Christian Gachet, Steve P Watson
GPVI, a major platelet activation receptor for collagen and fibrin, is considered as a particularly promising safe antithrombotic target. In this study, we show that human GPVI signals upon platelet adhesion to fibrinogen. Full spreading of human platelets on fibrinogen is abolished in platelets from GPVI-deficient patients suggesting that fibrinogen activates platelets through GPVI. While mouse platelets fail to spread on fibrinogen, human-GPVI-transgenic mouse platelets show full spreading and increased Ca2+ signalling through the tyrosine kinase Syk...
February 22, 2018: Haematologica
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