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https://www.readbyqxmd.com/read/28819568/nebivolol-attenuates-neutrophil-lymphocyte-ratio-a-marker-of-subclinical-inflammation-in-hypertensive-patients
#1
Mazhar Hussain, Muhammad Saeed, Muhammad Zafar Majeed Babar, Moazzam Ali Atif, Lubna Akhtar
BACKGROUND: High value of neutrophil lymphocyte ratio (NLR) is a strong independent predictor and biomarker of ongoing vascular inflammation in various cardiovascular disorders. OBJECTIVE: The main focus of the study is to investigate the effect of nebivolol on NLR in mild to moderate hypertensive patients in comparison with metoprolol. In addition, BMI, blood pressure, TLC count, blood sugar, and lipid profile were also assayed before and after treatment. MATERIALS AND METHODS: In this 12-week prospective double-blinded randomized study, 120 patients with mild to moderate hypertension were randomly divided into two groups to prescribed daily dose of tab nebivolol 5-10 mg and metoprolol 50-100 mg, respectively, for 12 weeks...
2017: International Journal of Hypertension
https://www.readbyqxmd.com/read/28811809/peppered-and-rare-gastric-and-duodenal-pseudomelanosis-a-case-series
#2
Sami Samiullah, Hadi Bhurgri, Arooj Babar, Fatima Samad, Moaz M Choudhary, Michael Demyen
Upper Gastrointestinal (GI) pseudomelanosis is an uncommon entity characterized by endoscopic visualization of speckled dark mucosal pigmentation. While described in the rectum and colon, 'melanosis' or more aptly 'pseudomelanosis' is rare in the duodenum and exceedingly rare in the stomach. Five cases of pseudomelanosis were encountered at our department. Four females and one male were diagnosed, with a mean age of 70 years. All patients exhibited duodenal pseudomelanosis, with one demonstrating gastric antral pseudomelanosis as well...
May 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28808567/community-based-saving-groups-an-innovative-approach-to-overcome-the-financial-and-social-barriers-in-health-care-seeking-by-the-women-in-the-rural-remote-communities-of-pakistan
#3
Babar Tasneem Shaikh, Qayyum Noorani, Shazia Abbas
BACKGROUND: In remote rural areas of Pakistan, access to the maternal, newborn and child health (MNCH) care provided by a skilled health provider is quite difficult. There are many reasons such as women's restricted social mobility, lack of education, disenfranchised in decision making and poverty. To overcome these barriers and impediments in district Chitral, which is the largest territory in terms of geography in province Khyber Pakhtunkhwa, local women of reproductive age, were mobilized to form the Community Based Saving Groups (CBSGs) at the village level...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28770845/particle-physics-babar-collaboration-first-to-see-anomaly
#4
COMMENT
Tom Browder, Giovanni Passaleva, Michael Roney
No abstract text is available yet for this article.
August 2, 2017: Nature
https://www.readbyqxmd.com/read/28765242/pulmonary-involvement-in-antineutrophil-cytoplasmic-antibodies-anca-associated-vasculitis-the-influence-of-anca-subtype
#5
Aladdin J Mohammad, Kristian H Mortensen, Judith Babar, Rona Smith, Rachel B Jones, Daiki Nakagomi, Pasupathy Sivasothy, David R W Jayne
OBJECTIVE: To describe pulmonary involvement at time of diagnosis in antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV), as defined by computed tomography (CT). METHODS: Patients with thoracic CT performed on or after the onset of AAV (n = 140; 75 women; granulomatosis with polyangiitis, n = 79; microscopic polyangiitis MPA, n = 61) followed at a tertiary referral center vasculitis clinic were studied. Radiological patterns of pulmonary involvement were evaluated from the CT studies using a predefined protocol, and compared to proteinase 3 (PR3)-ANCA and myeloperoxidase (MPO)-ANCA specificity...
August 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28764278/comparison-of-polymerase-chain-reaction-and-immunohistochemistry-assays-for-analysing-human-papillomavirus-infection-in-oral-squamous-cell-carcinoma
#6
Muhammad Sohail Awan, Babar Irfan, Ibrahim Zahid, Yumna Mirza, Syed Adnan Ali
INTRODUCTION: Polymerase Chain Reaction (PCR) and Immunohistochemistry (IHC) are two well-known techniques used for the diagnoses of genetic diseases, tumours and different pathogens. PCR basically amplify regions of DNA within a single molecule which may have etiologic significance, it is a method for in vitro amplification of specific DNA or RNA sequences, whereas IHC is used to verify tissue constituents (the antigens) with the utilization of specific antibodies that can be visualized through staining...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28754159/the-role-of-electrical-stimulation-in-the-management-of-avascular-necrosis-of-the-femoral-head-in-adults-a-systematic-review
#7
Talal Al-Jabri, Jessica Yan Qi Tan, Gabriel Yihan Tong, Ravikiran Shenoy, Babar Kayani, Timothy Parratt, Tahir Khan
BACKGROUND: Avascular necrosis of the femoral head causes significant morbidity and occurs in up to 20,000 people per year. A variety of nonoperative and operative measures have been trialled however a definitive treatment algorithm is yet to be established. Young adults in many cases have undergone multiple surgical procedures in their lifetime with increasing risks of complications. Less invasive techniques may help reduce the number of operations required and positively influence the natural history of the disease process...
July 28, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28749397/action-oriented-colour-coded-foot-length-calliper-for-primary-healthcare-workers-as-a-proxy-for-birth-weight-gestational-period
#8
Asha K Pratinidhi, Abhijit C Bagade, Satish V Kakade, Hemangi P Kale, Vinayak Y Kshirsagar, Rohini Babar, Shilpa Bagal
BACKGROUND & OBJECTIVES: Foot length of the newborn has a good correlation with the birth weight and is recommended to be used as a proxy measure. There can be variations in the measurement of foot length. A study was, therefore, carried out to develop a foot length calliper for accurate foot length measurement and to find cut-off values for birth weight and gestational age groups to be used by primary healthcare workers. METHODS: This study was undertaken on 645 apparently healthy newborn infants with known gestational age...
March 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28724411/a-qualitative-study-exploring-perceptions-and-attitudes-of-community-pharmacists-about-extended-pharmacy-services-in-lahore-pakistan
#9
Furqan K Hashmi, Mohamed Azmi Hassali, Adnan Khalid, Fahad Saleem, Hisham Aljadhey, Zaheer Ud Din Babar, Mohammad Bashaar
BACKGROUND: In recent decades, community pharmacies reported a change of business model, whereby a shift from traditional services to the provision of extended roles was observed. However, such delivery of extended pharmacy services (EPS) is reported from the developed world, and there is scarcity of information from the developing nations. Within this context, the present study was aimed to explore knowledge, perception and attitude of community pharmacists (CPs) about EPS and their readiness and acceptance for practice change in the city of Lahore, Pakistan...
July 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28718227/anti-microbial-resistance-in-pakistan-a-public-health
#10
EDITORIAL
Babar Tasneem Shaikh
No abstract text is available yet for this article.
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28716375/aging-and-post-intensive-care-syndrome-a-critical-need-for-geriatric-psychiatry
#11
REVIEW
Sophia Wang, Duane Allen, You Na Kheir, Noll Campbell, Babar Khan
Because of the aging of the intensive care unit (ICU) population and an improvement in survival rates after ICU hospitalization, an increasing number of older adults are suffering from long-term impairments because of critical illness, known as post-intensive care syndrome (PICS). This article focuses on PICS-related cognitive, psychological, and physical impairments and the impact of ICU hospitalization on families and caregivers. The authors also describe innovative models of care for PICS and what roles geriatric psychiatrists could play in the future of this rapidly growing population...
June 1, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28712202/stillbirths-what-can-be-done-to-confront-an-invisible-public-health-problem-in-pakistan
#12
Babar Tasneem Shaikh, Assad Hafeez, Saima Hamid
Pakistan has been ranked highest and appears worst in stillbirths' rate according to the recent global estimates. Reasons could be manifold; socio-cultural, health system related country specific, and some of these of course déjà vu, i.e., the biomedical causes. Yet, a fresh stocktaking is necessary to understand the complex phenomenon in a country, awfully affected by this menace. Maternal, neonatal and child health program needs to be informed and geared up toward addressing the actual reasons behind this heavy toll of stillbirths in Pakistan...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28704793/genome-and-transcriptome-wide-analyses-of-cellulose-synthase-gene-superfamily-in-soybean
#13
Muhammad Amjad Nawaz, Hafiz Mamoon Rehman, Faheem Shehzad Baloch, Babar Ijaz, Muhammad Amjad Ali, Iqrar Ahmad Khan, Jeong Dong Lee, Gyuhwa Chung, Seung Hwan Yang
The plant cellulose synthase gene superfamily belongs to the category of type-2 glycosyltransferases, and is involved in cellulose and hemicellulose biosynthesis. These enzymes are vital for maintaining cell-wall structural integrity throughout plant life. Here, we identified 78 putative cellulose synthases (CS) in the soybean genome. Phylogenetic analysis against 40 reference Arabidopsis CS genes clustered soybean CSs into seven major groups (CESA, CSL A, B, C, D, E and G), located on 19 chromosomes (except chromosome 18)...
August 2017: Journal of Plant Physiology
https://www.readbyqxmd.com/read/28696245/the-histone-codes-for-meiosis
#14
REVIEW
Lina Wang, Zhiliang Xu, Muhammad Babar Khawar, Chao Liu, Wei Li
Meiosis is a specialized process that produces haploid gametes from diploid cells by a single round of DNA replication followed by two successive cell divisions. It contains many special events, such as programmed DNA double-strand break (DSB) formation, homologous recombination, crossover formation and resolution. These events are associated with dynamically regulated chromosomal structures, the dynamic transcriptional regulation and chromatin remodeling are mainly modulated by histone modifications, termed 'histone codes'...
September 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/28692359/prevention-of-limb-length-discrepancy-in-total-hip-arthroplasty
#15
Babar Kayani, Jurek Pietrzak, Fahad S Hossain, Sujith Konan, Fares S Haddad
Total hip arthroplasty is a highly effective and cost-efficient procedure but postoperative limb length discrepancy is a common source of patient dissatisfaction and litigation. This article provides a systematic, stepwise approach for identifying and proactively managing risk factors associated with limb length discrepancy following total hip arthroplasty. This review explores preoperative history taking, clinical examination, radiological templating, implant positioning, soft tissue balancing, and intraoperative surgical techniques for minimizing leg length discrepancy while maintaining stability and restoring mechanical function following total hip arthroplasty...
July 2, 2017: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/28689859/pancreatitis-with-normal-lipase-and-amylase-in-setting-of-end-stage-renal-disease
#16
Anuj Sharma, Umair Masood, Babar Khan, Kunal Chawla, Divey Manocha
Pancreatitis with normal lipase and amylase level is a rare phenomenon. This is especially true in patient with end-stage renal disease as lipase and amylase are renally excreted. Literature review reveals previous case report of pancreatitis with normal lipase and amylase level, however, none of them occurred in the setting of end-stage renal disease. Our case is the first such reported case of pancreatitis in such setting. Here we report a 30year old male with past medical history of end-stage renal disease who presented in emergency department with acute abdominal pain...
July 5, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28671710/adult-xanthogranuloma-diagnosed-on-reflectance-confocal-microscopy
#17
LETTER
Attiya Haroon, Shahram Shafi, Babar Rao
No abstract text is available yet for this article.
September 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28653910/oral-supplementation-of-thuja-oreintalis-leaf-extract-moderately-affects-the-behavior-in-albino-mice-in-a-gender-specific-manner
#18
Bushra Riaz, Rubab Iftikhar Khan Babar, Shahid Iqbal, Muhammad Ali, Furhan Iqbal
Present study was designed to demonstrate the effect ethanolic leaf extract of Thuja orientalis on the learning and memory formation in albino mice. Four week old albino mice were either orally supplemented with 50mg/ml solvent/Kg body weight of Thuja orientalis or with equal volume of saline solution (0.9% NaCl) for seven days. A battery of neurological tests (Elevated plus maze, Rota Rod, light and dark box, open field and novel object recognition test) were applied at the end of dose supplementation. Thuja orientalis leaf extract treated female mice spent significantly les time on rotating rod (P = 0...
May 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28651923/randomized-controlled-trials-covering-pharmaceutical-care-and-medicines-management-a-systematic-review-of-literature
#19
REVIEW
Zaheer-Ud-Din Babar, Rozina Kousar, Ghulam Murtaza, Saira Azhar, Shujaat Ali Khan, Louise Curley
OBJECTIVE: To review the effects of pharmaceutical care on hospitalizations, mortality and clinical outcomes in patients. METHODS: Systematic searches were conducted in MEDLINE, EMBASE and International Pharmaceutical Abstracts (IPA) databases to identify studies that were published between 2004 and January 2017. Studies included in this review were randomized controlled trials (RCTs) that spanned across both community and hospital settings. Using strict inclusion/exclusion criteria studies were included if they reported level 1 or 2 outcomes in the hierarchy of outcome measure i...
June 19, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28650326/to-evaluate-the-efficacy-and-safety-of-cofnovex-plus-ema-syrup
#20
Zubair Ali, Muhammad Daniyal, Muhammad Khalid Adhia, Anees Alam, Babar Sarfaraz, Abdul Sattar, Khan Usmanghani
The cough and cold are very widespread conditions and a common purpose for advice in general practice. Utmost often the sign and symptoms of cough are produced by acute viral airway infection and the course is frequently benign. But it can be converted into bacterial super-infection and can cause acute bronchitis. Herbal medicines are used to treat symptoms of the cough and cold, and among these medicines Ivy leaf is used to treat mucous discharge and irritation in throat due to the cough and cold. In addition to synthetic substances such as acetylcysteine, carbocisteins, ambroxol and bromhexine, herbal medicines contain saponins, which are used in these indications...
March 2017: Pakistan Journal of Pharmaceutical Sciences
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