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https://www.readbyqxmd.com/read/29679898/heart-rate-variability-alterations-in-late-life-depression-a-meta-analysis
#1
REVIEW
Lydia Brown, Chandan Karmakar, Richard Gray, Ripu Jindal, Terrence Lim, Christina Bryant
OBJECTIVE: There is strong evidence for a bi-directional relationship between heart-health and depression in later life, but the physiological mechanisms underlying this relationship remain unclear. Heart rate variability is one promising factor that might help explain this relationship. We present results of a meta-analysis that considers heart rate variability alterations in older adults with depression. METHODS: Literature search of Embase, PsychInfo and Medline revealed five clinical studies and six observational studies that examined the relationship between heart rate variability and depression in adults with a mean age over 60...
April 10, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29679893/identification-of-homocysteine-suppressive-mitochondrial-etc-complex-genes-and-tissue-expression-profile-novel-hypothesis-establishment
#2
Ramon Cueto, Lixiao Zhang, Hui Min Shan, Xiao Huang, Xinyuan Li, Ya-Feng Li, Jahaira Lopez, William Y Yang, Muriel Lavallee, Catherine Yu, Yong Ji, Xiaofeng Yang, Hong Wang
Hyperhomocysteinemia (HHcy) is an independent risk factor for cardiovascular disease (CVD) which has been implicated in matochondrial (Mt) function impairment. In this study, we characterized Hcy metabolism in mouse tissues by using LC-ESI-MS/MS analysis, established tissue expression profiles for 84 nuclear-encoded Mt electron transport chain complex (nMt-ETC-Com) genes in 20 human and 19 mouse tissues by database mining, and modeled the effect of HHcy on Mt-ETC function. Hcy levels were high in mouse kidney/lung/spleen/liver (24-14 nmol/g tissue) but low in brain/heart (~5 nmol/g)...
April 4, 2018: Redox Biology
https://www.readbyqxmd.com/read/29679848/a-deep-boltzmann-machine-driven-level-set-method-for-heart-motion-tracking-using-cine-mri-images
#3
Jian Wu, Thomas R Mazur, Su Ruan, Chunfeng Lian, Nalini Daniel, Hilary Lashmett, Laura Ochoa, Imran Zoberi, Mark A Anastasio, H Michael Gach, Sasa Mutic, Maria Thomas, Hua Li
Heart motion tracking for radiation therapy treatment planning can result in effective motion management strategies to minimize radiation-induced cardiotoxicity. However, automatic heart motion tracking is challenging due to factors that include the complex spatial relationship between the heart and its neighboring structures, dynamic changes in heart shape, and limited image contrast, resolution, and volume coverage. In this study, we developed and evaluated a deep generative shape model-driven level set method to address these challenges...
April 6, 2018: Medical Image Analysis
https://www.readbyqxmd.com/read/29679789/tissue-bioconcentration-and-effects-of-fluoxetine-in-zebrafish-danio-rerio-and-red-crucian-cap-carassius-auratus-after-short-term-and-long-term-exposure
#4
Chenyuan Pan, Ming Yang, Hai Xu, Bentuo Xu, Lihui Jiang, Minghong Wu
Fluoxetion (FLU) is an antidepressant pharmaceutical most commonly detected in the aquatic environment. The present study aims to elucidate the tissue accumulation and effects of FLU using two different fish models. First, the multiple effects and the FLU levels in fish, were examined in zebrafish (Danio rerio) embryos exposed to FLU concentrations (0, 0.1, 1, 10, 100, 1000 μg/L) from 4 h post-fertilization (hpf) until 120 hpf. Exposure to FLU accelerated heart rates, postponed hatching time, and increased swimming speed of fish...
April 16, 2018: Chemosphere
https://www.readbyqxmd.com/read/29679725/achyranthis-bidentatae-radix-enhanced-articular-distribution-and-anti-inflammatory-effect-of-berberine-in-sanmiao-wan-using-an-acute-gouty-arthritis-rat-model
#5
Juan Wu, Jingya Li, Wei Li, Bei Sun, Jin Xie, Wenming Cheng, Qunlin Zhang
ETHNOPHARMACOLOGICAL RELEVANCE: Sanmiao Wan (SMW) has been a basic prescription employed for the treatment for gout in the clinic since Yuan dynasty. Achyranthis bidentatae radix (ABR) is designed as a lower-guiding drug in SMW to augment the articular accumulation of active ingredients and improve the anti-inflammatory effect. AIM OF THE STUDY: Present study was undertaken to investigate the dose-response relationship of berberine in SMW between the articular concentration and anti-inflammatory effect in the knee joint under the lower-guiding of ABR...
April 18, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29679716/using-artificial-intelligence-in-an-intelligent-way-to-improve-efficiency-of-a-heart-failure-care-team
#6
EDITORIAL
Griffin M Weber
No abstract text is available yet for this article.
April 18, 2018: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/29679700/toxicity-of-porcelain-fused-to-metal-substrate-to-zebrafish-danio-rerio-embryos-and-larvae
#7
Libo Zhao, Jing Si, Yuan Wei, Sirui Li, Yanjiao Jiang, Rong Zhou, Bin Liu, Hong Zhang
AIMS: Porcelain-fused-to-metal (PFM) crowns are a standard restoration technique in dentistry, but toxicity of PFM in vivo has not been systematically evaluated. The present study evaluated the effects of various metal alloy shells of PFM crowns on the development of zebrafish embryos and larvae in order to determine the safety of these materials. MAIN METHODS: Gold palladium (Au-Pd), silver palladium (Ag-Pd), Nickel chromium (Ni-Cr), cobalt chromium (Co-Cr), titanium (Ti) alloy porcelain crowns were immersed in artificial saliva for 1, 4, and 7 weeks, and the leach solution was collected and used to treat zebrafish embryos at 4-144 h PFM...
April 18, 2018: Life Sciences
https://www.readbyqxmd.com/read/29679697/-all-citizens-of-the-world-can-save-a-life-the-world-restart-a-heart-wrah-initiative-starts-in-2018
#8
B W Böttiger, A Lockey, R Aickin, M Castren, A de Caen, R Escalante, K B Kern, S H Lim, V Nadkarni, R W Neumar, J P Nolan, D Stanton, T-L Wang, G D Perkins
No abstract text is available yet for this article.
April 18, 2018: Resuscitation
https://www.readbyqxmd.com/read/29679660/effects-of-aerobic-training-resistance-training-or-both-on-brain-derived-neurotrophic-factor-in-adolescents-with-obesity-the-hearty-randomized-controlled-trial
#9
Gary S Goldfield, Glen P Kenny, Denis Prud'Homme, Martin Holcik, Angela S Alberga, Margaret Fahnestock, Jameason D Cameron, Steve Doucette, Stasia Hadjiyannakis, Heather Tulloch, Mark S Tremblay, Jeremy Walsh, Eva Guerin, Katie E Gunnell, Amedeo D'Angiulli, Ronald J Sigal
Brain derived neurotrophic factor (BDNF) is a protein that plays a critical role in modulating cognition in animals and humans. Aerobic exercise often increases BDNF in adults, but effects of this exercise modality and others among adolescents remain uncertain. This study examined the effects of aerobic training, resistance training, and combined training on resting serum BDNF levels in adolescents with overweight and obesity. After a 4-week pre-randomization treatment, 304 post-pubertal, adolescents with overweight or obesity (70% females) aged 14-18 years were randomized to one of four groups for 22 weeks: aerobic training (N = 75), resistance training (N = 78), combined aerobic and resistance training (N = 75), or non-exercising control (N = 76)...
April 18, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29679659/measurement-of-emotional-contagion-using-synchronization-of-heart-rhythm-pattern-between-two-persons-application-to-sales-managers-and-sales-force-synchronization
#10
Sangin Park, Soo Ji Choi, Sungchul Mun, Mincheol Whang
The purpose of this study was to measure emotional contagion, determine its direction, and compare the intensity between positive and negative contagion using the synchronization of heart rhythm pattern (HRP). A total of 64 undergraduate students (32 women and 32 men) participated in the experiment, and were randomly categorized as either leaders or followers. Followers were required to imitate the facial expression (happy and sad) of the leader (emotional contagion) or of a facial image (emotional non-contagion)...
April 18, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29679652/effects-of-phenidone-duclox-2-5-inhibitor-against-n-methyl-n-nitrosourea-induced-mammary-gland-carcinoma-in-albino-rats
#11
Swetlana Gautam, Soniya Rani, Gaurav Kaithwas
The present study was designed to evaluate the effects of Phenidone (Dual inhibitor of COX-2 and 5-LOX, DuCLOX-2/5) on various aspects of cancer chemoprevention against MNU induced mammary gland carcinoma. MNU treated rat showed altered heart rate variability (HRV), increased alveolar bud count, differentiation score, up regulated inflammatory enzyme markers (COX, LOX, NO and H2S) and distorted oxidative stress markers (TBARs, protein carbonyl, SOD, catalase and GSH). The mammary gland surface architecture was studied using carmine staining and H&E staining...
April 18, 2018: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/29679609/cannabis-sativa-marijuana-alters-blood-chemistry-and-the-cytoarchitecture-of-some-organs-in-sprague-dawley-rat-models
#12
Nosarieme Omoregie Abey
There is evidence that Cannabis whose active ingredient is tetrahydrocannabinol (THC) is the most commonly abused neuroactive substance, among young adults. This work investigated the effects of Cannabis sativa on the cytoarchitecture of some key organs and the blood chemistry of rat models. Twenty-one (21) male Sprague Dawley rats were fed different percentage of cannabis chow (0%, 5% and 10%) for a period of seven (7) weeks. Rats were subjected to intermittent cognitive function test and sacrificed after the seventh week, collecting the blood, brain and other important tissues for analysis which include; brain total protein and nitric oxide concentration, blood chemistry and histopathology...
April 18, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29679591/the-intrauterine-device-as-emergency-contraception-how-much-do-young-women-know
#13
Suzan R Goodman, Alison M El Ayadi, Corinne H Rocca, Julia E Kohn, Courtney E Benedict, Jessica R Dieseldorff, Cynthia C Harper
BACKGROUND: Unprotected intercourse is common, especially among teens and young women. Access to intrauterine device (IUD) as emergency contraception (EC) can help interested patients more effectively prevent unintended pregnancy and can also offer ongoing contraception. This study evaluated young women's awareness of IUD as EC and interest in case of need. STUDY DESIGN: We conducted a secondary analysis of data from young women, ages 18-25years, not desiring pregnancy within 12months, and receiving contraceptive counseling within a cluster-randomized trial in 40U...
April 18, 2018: Contraception
https://www.readbyqxmd.com/read/29679541/treatment-with-d-%C3%AE-hydroxybutyrate-protects-heart-from-ischemia-reperfusion-injury-in-mice
#14
Yongsheng Yu, Yunhua Yu, Yuefan Zhang, Zhigang Zhang, Weishuai An, Xianxian Zhao
The present study was designed to examine the protection of D-β-hydroxybutyrate (BHB) against ischemia/reperfusion (I/R) injury in heart and investigate its underlying mechanism. Male adult mice were exposed to 30min of ischemia and 24h of reperfusion. Osmotic pumps were implanted subcutaneously 5min before reperfusion for continuous delivery of the exogenous BHB (1.6mmol/kg/24h). Treatment with BHB reduced infarct size and levels of cardiac troponin I, creatine kinase and lactate dehydrogenase in serum, attenuated apoptosis in myocardium, and preserved cardiac function of I/R mice...
April 18, 2018: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29679534/determinants-of-reverse-remodeling-of-the-left-atrium-following-transaortic-myectomy
#15
Anita Nguyen, Hartzell V Schaff, Rick A Nishimura, Joseph A Dearani, Jeffrey B Geske, Brian D Lahr, Steve R Ommen
BACKGROUND: In patients with hypertrophic cardiomyopathy (HCM), enlargement of the left atrium (LA) is associated with increased morbidity and mortality due to risk of atrial fibrillation (AF), stroke, and heart failure. In this study, we investigated whether LA reverse remodeling occurs following septal myectomy. METHODS: Between March 2007 and July 2015, 656 patients underwent myectomy at our institution and had pre- and postoperative transthoracic echocardiographic (TTE) recording of LA volume index (LAVI)...
April 18, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29679498/7t-ultra-high-field-body-mr-imaging-with-an-8-channel-transmit-32-channel-receive-radiofrequency-coil-array
#16
Stefan H G Rietsch, Stephan Orzada, Stefan Maderwald, Sascha Brunheim, Bart W J Philips, Tom W J Scheenen, Mark E Ladd, Harald H Quick
PURPOSE: In this work a combined body coil array with 8 transmit/receive (Tx/Rx) meander elements and with 24 receive-only (Rx) loops (8Tx/32Rx) was developed and evaluated in comparison to an 8-channel transmit/receive body array (8Tx/Rx) based on meander elements serving as the reference standard. METHODS: Systematic evaluation of the RF array was performed on a body-sized phantom. Body imaging at 7T was performed in 6 volunteers in the body regions pelvis, abdomen, and heart...
April 21, 2018: Medical Physics
https://www.readbyqxmd.com/read/29679418/family-involvement-in-rehabilitation-coronary-artery-disease-patients-perspectives
#17
Sonja Tuomisto, Meeri Koivula, Päivi Åstedt-Kurki, Mika Helminen
AIMS AND OBJECTIVES: The aim of this paper is to describe CAD -patients' perceptions of family involvement in rehabilitation and the connection between background factors and family involvement. BACKGROUND: CAD-patients hospital stays can be very concise. Family members can support rehabilitation, but many challenges can emerge. There is a need to nurture patients and family members in an individual way and to recognize their concerns. More accurate patient education should be available for patients and their family members...
April 21, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29679415/elite-swimmers-internal-markers-trajectories-in-ecological-training-conditions
#18
Philippe Vacher, Guillaume Martinent, Laurent Mourot, Michel Nicolas
PURPOSE: This study examined the trajectories of elite swimmers' recovery-stress states and cardiac vagal-related markers during a three-month training period preceding the national championship and their within-person relationships with perceived control. METHODS: A Multilevel Growth Curve Analysis (MGCA) approach was used with 21 male elite swimmers. Four waves of assessments of psychological (stress, recovery, perceived control) and physiological (heart rate variability, HRV) markers were completed during a three-month training preparation leading to a major competition...
April 21, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29679405/who-you-are-and-where-you-live-can-determine-how-long-you-live-what-nurses-need-to-know-about-cardiovascular-disease-among-low-income-urban-dwelling-minority-communities
#19
EDITORIAL
Diana-Lyn Baptiste
Urban populations across the globe face unique health challenges in relationship to gender, race, geographical location and socioeconomic status. The global burden of cardiovascular disease is growing problem accounting for 17.3 million deaths in 2013 and projected to increase to 23.6 million by 2030 (American Heart Association, 2017; World Health Organization, 2018). Like many other countries, in the United States, cardiovascular disease is endemic, remaining the greatest cause of hospitalization and mortality; attributing to more than 45% of deaths among American adults (American Heart Association, 2017)...
April 21, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29679364/estimates-of-medication-expenditure-for-ischemic-heart-disease-accompanying-chronic-obstructive-pulmonary-disease
#20
Edyta Rysiak, Izabela Prokop, Ilona Zaręba, Robert M Mróz
Ischemic heart disease (IHD) is a frequent accompaniment of chronic obstructive pulmonary disease (COPD). Co-occurrence of these two diseases is associated with many risk factors, difficulties in implementing appropriate therapies, numerous complications, and high spending for treatment. All these elements significantly reduce the quality of life of patients. The aim of this study was to estimate the expenditure for medications involved with IHD pharmacotherapy in the course of COPD. This retrospective study was based on the review of medical files of 57 patients, 27 women and 30 men, diagnosed with IHD, according to the severity classification, in the course of COPD which was staged according to the GOLD criteria...
April 21, 2018: Advances in Experimental Medicine and Biology
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