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https://www.readbyqxmd.com/read/28823072/prevalence-and-predictors-of-digoxin-utilization-among-heart-failure-patients-with-reduced-ejection-fraction-in-qatar
#1
Alaa Abdullah Rahhal, Ahmed Awaisu, Kawthar M Tawengi, Safae AbuYousef, Lylia Mekideche
Background Digoxin is a cardiac glycoside that is recommended by clinical practice guidelines to be used in patients with heart failure with reduced ejection fraction (HFrEF) who still have persistent symptoms despite optimal medical therapy. However, this recommendation is based on limited and old trial data. Moreover, pharmacoepidemiologic studies are important in determining the prevalence of digoxin use and factors influencing this. Objective This study aimed to determine the prevalence and the predictors of digoxin utilization among patients with HFrEF with or without atrial fibrillation (AF) in Qatar...
August 19, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28822900/supportive-care-pathway-functionalities-of-ehr-system-in-a-saudi-arabian-hospital
#2
Bakheet Aldosari
BACKGROUND: Electronic health record (EHR) is a data management system used in healthcare services. The stored medical information in EHR can be accessed and utilized by authorized users, which helps clinicians in making clinical decisions. Therefore, this study aims at comparing the embedded clinical guidelines or the supportive pathway functions as well as their compliance level in the two EMR systems, i.e. QuadraMed (QCPR) and BestCare. METHODS: A test vignette was used to evaluate the features, functions, performance, and output to assess the EHR clinical path way functionality of the QCPR and BestCare...
August 12, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28821246/examining-database-persistence-of-iso-en-13606-standardized-electronic-health-record-extracts-relational-vs-nosql-approaches
#3
Ricardo Sánchez-de-Madariaga, Adolfo Muñoz, Raimundo Lozano-Rubí, Pablo Serrano-Balazote, Antonio L Castro, Oscar Moreno, Mario Pascual
BACKGROUND: The objective of this research is to compare the relational and non-relational (NoSQL) database systems approaches in order to store, recover, query and persist standardized medical information in the form of ISO/EN 13606 normalized Electronic Health Record XML extracts, both in isolation and concurrently. NoSQL database systems have recently attracted much attention, but few studies in the literature address their direct comparison with relational databases when applied to build the persistence layer of a standardized medical information system...
August 18, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28818549/integration-of-dpc-and-clinical-microbiological-data-in-japan-reveals-importance-of-confirming-a-negative-follow-up-blood-culture-in-patients-with-mrsa-bacteremia
#4
Naoki Miyamoto, Koji Yahara, Rie Horita, Tomomi Yano, Naotaka Tashiro, Daiichi Morii, Atsuko Tsutsui, Kenichiro Yaita, Keigo Shibayama, Hiroshi Watanabe
Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is one of the commonest and most life-threatening of all infectious diseases. The morbidity and mortality rates associated with MRSA bacteremia are higher than those associated with bacteremia caused by other pathogens. A common guideline in MRSA bacteremia treatment is to confirm bacteremia clearance through additional blood cultures 2-4 days after initial positive cultures and as needed thereafter. However, no study has presented statistical evidence of how and to what extent confirming a negative follow-up blood culture impacts clinical outcome...
August 14, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28818007/kiwi-omnicup-handheld-vs-mityvac-m-style-conventional-vacuum-system-a-retrospective-observational-study
#5
Tal Weissbach, Nasreen Hag-Yahia, Michal Ovadia, Keren Tzadikevitch Geffen, Omer Weitzner, Tal Biron-Shental
INTRODUCTION: To improve choice of vacuum-assisted delivery (VAD) system, we compared outcomes of Kiwi handheld system and Mityvac M-style conventional system (both use disposable plastic cups). MATERIALS AND METHODS: Retrospective observational study with data collection from electronic medical records. The study was conducted at a tertiary medical center, with approximately 7000 deliveries annually. Categorical and continuous variables were analyzed using chi-square test and t-test, respectively...
August 17, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28817791/using-practice-facilitation-to-increase-rates-of-colorectal-cancer-screening-in-community-health-centers-north-carolina-2012-2013-feasibility-facilitators-and-barriers
#6
Bryan J Weiner, Catherine L Rohweder, Jennifer E Scott, Randall Teal, Alecia Slade, Allison M Deal, Naima Jihad, Marti Wolf
INTRODUCTION: Practice facilitation involves trained individuals working with practice staff to conduct quality improvement activities and support delivery of evidence-based clinical services. We examined the feasibility of using practice facilitation to assist federally qualified health centers (FQHCs) to increase colorectal cancer screening rates in North Carolina. METHODS: The intervention consisted of 12 months of facilitation in 3 FQHCs. We conducted chart audits to obtain data on changes in documented recommendation for colorectal cancer screening and completed screening...
August 17, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28816917/factors-associated-with-developmental-behavioral-pediatricians-prescribing-psychotropic-medication-to-children-with-autism-spectrum-disorder-a-study-of-three-dbpnet-sites
#7
Carissa Jackel, Justine Shults, Susan Wiley, Jareen Meinzen-Derr, Marilyn Augustyn, Nathan Blum
OBJECTIVE: Psychotropic medications are frequently prescribed to children with autism spectrum disorder (ASD), but little is known about the prescribing practices of developmental-behavioral pediatricians (DBPs). Our objective was to determine whether clinical site, age, insurance, or comorbidities influenced DBPs prescribing psychotropic medication for children with ASD. METHODS: A retrospective analysis was performed using electronic health record data of all patients with ASD seen at 3 academic developmental-behavioral pediatrics (DBP) clinical programs from January 2010 to December 2011...
August 10, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28816111/updated-2014-stopp-criteria-to-identify-potentially-inappropriate-prescribing-in-community-dwelling-in-elderly-patients%C3%A2
#8
María Luisa Nicieza-Garcia, Gloria Manso, Esther Salgueiro
OBJECTIVE: To analyze potentially inappropriate prescribing (PIP) using the 2014 version of STOPP criteria. MATERIALS AND METHODS: Prescriptions were analyzed by using invoicing data and electronic medical records. RESULTS: At least one STOPP criterion was observed in 9 out of every 10 patients. The most common STOPP criteria found were: "any drug prescribed without an evidence-based clinical indication" and "any drug prescribed beyond the recommended duration, where treatment duration is well defined"...
August 17, 2017: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28815772/ectropion-improvement-with-topical-tazarotene-in-children-with-lamellar-ichthyosis
#9
Brooke Hanson, Lauren Becker, Kristen Hook, Ingrid Polcari, Raymond G Areaux, Sheilagh Maguiness
BACKGROUND/OBJECTIVES: Lamellar ichthyosis (LI) is a well-described phenotypic subtype of autosomal recessive congenital ichthyosis (ARCI). The condition typically presents at birth with collodion membrane and leads to thick, plate-like scaling of the skin throughout the body, alopecia, and prominent ocular manifestations. Ocular complications include bilateral cicatricial ectropion and lagophthalmos. These ocular complications can lead to chronic exposure keratitis and in some cases corneal ulceration and blindness...
August 17, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28815546/clusters-of-week-specific-maternal-gestational-weight-gain-pattern-and-their-association-with-birthweight-an-observational-cohort-study
#10
Huan Liang, Chuanmin Yin, Xinran Dong, Ganesh Acharya, Xiaotian Li
INTRODUCTION: Gestational weight gain (GWG) varies widely among different populations, and an inappropriate GWG is associated with adverse pregnancy outcomes. We aimed to investigate week-specific serial changes in GWG in an urban Chinese population to derive clusters of GWG pattern and explore the impact of GWG patterns on birthweight. MATERIAL AND METHODS: This was an observational cohort study of 6130 women delivered at a university hospital in Shanghai, China...
August 16, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28815480/evaluation-of-electronic-healthcare-databases-for-post-marketing-drug-safety-surveillance-and-pharmacoepidemiology-in-china
#11
Yu Yang, Xiaofeng Zhou, Shuangqing Gao, Hongbo Lin, Yanming Xie, Yuji Feng, Kui Huang, Siyan Zhan
INTRODUCTION: Electronic healthcare databases (EHDs) are used increasingly for post-marketing drug safety surveillance and pharmacoepidemiology in Europe and North America. However, few studies have examined the potential of these data sources in China. METHODS: Three major types of EHDs in China (i.e., a regional community-based database, a national claims database, and an electronic medical records [EMR] database) were selected for evaluation. Forty core variables were derived based on the US Mini-Sentinel (MS) Common Data Model (CDM) as well as the data features in China that would be desirable to support drug safety surveillance...
August 16, 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/28815152/populating-physician-biographical-pages-based-on-emr-data
#12
Feichen Shen, Sunghwan Sohn, Majid Rastegar-Mojarad, Sijia Liu, Joshua J Pankratz, Michael A Hatton, Nancy Sowada, Om K Shrestha, Shawna L Shurson, Hongfang Liu
The physicians' biographical pages are essential in providing information about physicians' specialties. However, physicians may not have biographical pages or the current pages are not comprehensive. We hypothesize that physicians' specialty information can be mined from Electronic Medical Records (EMRs) of their patients. We proposed an automated physician specialty populating (PSP) system that analyzes physician-ascertained diagnoses in EMRs, aggregates them to an appropriate granularity based on the current biographical pages, and populates the biographical pages accordingly...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28815151/eye-tracking-for-clinical-decision-support-a-method-to-capture-automatically-what-physicians-are-viewing-in-the-emr
#13
Andrew J King, Harry Hochheiser, Shyam Visweswaran, Gilles Clermont, Gregory F Cooper
Eye-tracking is a valuable research tool that is used in laboratory and limited field environments. We take steps toward developing methods that enable widespread adoption of eye-tracking and its real-time application in clinical decision support. Eye-tracking will enhance awareness and enable intelligent views, more precise alerts, and other forms of decision support in the Electronic Medical Record (EMR). We evaluated a low-cost eye-tracking device and found the device's accuracy to be non-inferior to a more expensive device...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28815147/triangulating-methodologies-from-software-medicine-and-human-factors-industries-to-measure-usability-and-clinical-efficacy-of-medication-data-visualization-in-an-electronic-health-record-system
#14
Bora Chang, Manoj Kanagaraj, Ben Neely, Noa Segall, Erich Huang
Within the last decade, use of Electronic Health Record (EHR) systems has become intimately integrated into healthcare practice in the United States. However, large gaps remain in the study of clinical usability and require rigorous and innovative approaches for testing usability principles. In this study, validated tools from the core functions that EHRs serve-software, medicine and human factors-were combined to holistically understand and objectively measure usability of medication data displays. The first phase of this study included 132 medical trainee participants who were randomized to one of two simulated EHR environments with either a medication list or a medication timeline visualization...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28815143/analyzing-electronic-medical-records-to-predict-risk-of-dit-death-intubation-or-transfer-to-icu-in-pediatric-respiratory-failure-or-related-conditions
#15
Teeradache Viangteeravat, Oguz Akbilgic, Robert Lowell Davis
Large volumes of data are generated in hospital settings, including clinical and physiological data generated during the course of patient care. Our goal, as proof of concept, was to identify early clinical factors or traits useful for predicting the outcome, of death, intubation, or transfer to ICU, for children with pediatric respiratory failure. We implemented both supervised and unsupervised methods to extend our understanding on statistical relationships in clinical and physiological data. As a supervised learning method, we use binary logistic regression to predict the risk of developing DIT outcome...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28815136/design-recommendations-for-pharmacogenomics-clinical-decision-support-systems
#16
Maher Khelifi, Peter Tarczy-Hornoch, Emily B Devine, Wanda Pratt
The use of pharmacogenomics (PGx) in clinical practice still faces challenges to fully adopt genetic information in targeting drug therapy. To incorporate genetics into clinical practice, many support the use of Pharmacogenomics Clinical Decision Support Systems (PGx-CDS) for medication prescriptions. This support was fueled by new guidelines to incorporate genetics for optimizing drug dosage and reducing adverse events. In addition, the complexity of PGx led to exploring CDS outside the paradigm of the basic CDS tools embedded in commercial electronic health records...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28815131/integrating-medication-alert-data-into-a-clinical-data-repository-to-enable-retrospective-study-of-drug-interaction-alerts-in-clinical-practice
#17
Mei Liu, Brittany L Melton, Gregory Ator, Lemuel R Waitman
Current clinical data repositories primarily extract data from multiple administrative and electronic medical record (EMR) data resources (e.g., hospital and physician billing records) containing specific patient-level data including demographics, medications, laboratory results, diagnoses, and procedure codes. It overlooks the importance of EMR system-level data (e.g., medication alerts that are routinely used by physicians, nurses, and pharmacists for decision support) for the surveillance of EMR decision support tools...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28815124/pheknow-cloud-a-tool-for-evaluating-high-throughput-phenotype-candidates-using-online-medical-literature
#18
Jette Henderson, Ryan Bridges, Joyce C Ho, Byron C Wallace, Joydeep Ghosh
As the adoption of Electronic Healthcare Records has grown, the need to transform manual processes that extract and characterize medical data into automatic and high-throughput processes has also grown. Recently, researchers have tackled the problem of automatically extracting candidate phenotypes from EHR data. Since these phenotypes are usually generated using unsupervised or semi-supervised methods, it is necessary to examine and validate the clinical relevance of the generated "candidate" phenotypes. We present PheKnow-Cloud, a framework that uses co-occurrence analysis on the publicly available, online repository ofjournal articles, PubMed, to build sets of evidence for user-supplied candidate phenotypes...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28815117/systematic-analysis-of-free-text-family-history-in-electronic-health-record
#19
Yanshan Wang, Liwei Wang, Majid Rastegar-Mojarad, Sijia Liu, Feichen Shen, Hongfang Liu
Family history is an important component in modern clinical care especially in the era of precision medicine. Family history information in the Electronic Health Record (EHR) system is usually stored in structured format as well as in free-text format. In this study, we systematically analyzed a family history text corpus from 3 million clinical notes for the patients receiving their primary care at Mayo Clinic. Family members, medical problems, and their associations were analyzed and reported. Our findings showed a great agreement between positive/negated medical problems mentioned in the diagnosis report and the family history, as measured by observed agreement and random agreement...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28815116/reducing-clinical-noise-for-body-mass-index-measures-due-to-unit-and-transcription-errors-in-the-electronic-health-record
#20
Robert Goodloe, Eric Farber-Eger, Jonathan Boston, Dana C Crawford, William S Bush
Body mass index (BMI) is an important outcome and covariate adjustment for many clinical association studies. Accurate assessment of BMI, therefore, is a critical part of many study designs. Electronic health records (EHRs) are a growing source of clinical data for research purposes, and have proven useful for identifying and replicating genetic associations. EHR-based data collected for clinical and billing purposes have several unique properties, including a high degree of heterogeneity or "clinical noise...
2017: AMIA Summits on Translational Science Proceedings
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