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https://www.readbyqxmd.com/read/27749977/working-on-a-standard-joint-unit-a-pilot-test
#1
Cristina Casajuana, Hugo López-Pelayo, María Mercedes Balcells, Laia Miquel, Lídia Teixidó, Joan Colom, Antoni Gual
INTRODUCTION: Assessing cannabis consumption remains complex due to no reliable registration systems. We tested the likelihood of establishing a Standard Joint Unit (SJU) which considers the main cannabinoids with implication on health through a naturalistic approach.  Methodology. Pilot study with current cannabis users of four areas of Barcelona: universities, nightclubs, out-patient mental health service, and cannabis associations. We designed and administered a questionnaire on cannabis use-patterns and determined the willingness to donate a joint for analysis...
October 7, 2016: Adicciones
https://www.readbyqxmd.com/read/27660881/use-of-marijuana-for-medical-purposes
#2
EDITORIAL
Jarosław Pinkas, Piotr Jabłoński, Michal Kidawa, Waldemar Wierzba
Cannabis is the most popular illicit drug on the European market. Over 16 million young Europeans have used it at least once in the last few years. The recent trends in the consumption of marihuana differ between countries. Some countries face an increase in the prevalence of cannabis use, including Poland, where the level cannabis use has been systematically increasing since the 1990's. According to a recent ESPAD study, 19% of Polish adolescents aged 15-16 have used cannabis in the last year. Marihuana is also a leading substance when analyzing the data of seizures and crimes...
September 2016: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/27619556/cannabis-cultivation-in-spain-a-profile-of-plantations-growers-and-production-systems
#3
Arturo Alvarez, Juan F Gamella, Iván Parra
BACKGROUND: The European market for cannabis derivatives is being transformed. The cultivation of cannabis within the EU and the shift of demand from hashish to domestic marihuana are key aspects of this transformation. Spain, formerly central to the trade of Moroccan hashish, is becoming a marihuana-producing country. The emergence of "import-substitution" has been researched in other EU countries, but thus far the Spanish case remains undocumented. METHODS: This paper is based on analysis of data of 748 cannabis plantations seized by Spanish police in 2013...
September 9, 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27590896/cannabis-sativa-allergy-looking-through-the-fog
#4
Ine I Decuyper, Athina L Van Gasse, Nathalie Cop, Vito Sabato, Margaretha Faber, Christel Mertens, Chris H Bridts, Margo M Hagendorens, Luc De Clerck, H P Rihs, Didier G Ebo
IgE-mediated Cannabis (C. sativa, marihuana) allergy seems to be on the rise. Both active and passive exposure to cannabis allergens may trigger a C. sativa sensitization and/or allergy. The clinical presentation of a C. sativa allergy varies from mild to life-threatening reactions and often seems to depend on the route of exposure. In addition, sensitization to cannabis allergens can result in various cross-allergies, mostly for plant foods. This clinical entity, designated as the "cannabis-fruit/vegetable syndrome" might also imply cross-reactivity with tobacco, natural latex and plant-food derived alcoholic beverages...
September 3, 2016: Allergy
https://www.readbyqxmd.com/read/27168633/opinions-of-hospital-pharmacists-in-canada-regarding-marijuana-for-medical-purposes
#5
Fiona Mitchell, Odette Gould, Michael LeBlanc, Leslie Manuel
BACKGROUND: Canada's most recent Marihuana for Medical Purposes Regulations have changed the way in which patients access marijuana. Furthermore, if authorized by the person in charge of the hospital, a pharmacist practising in a hospital may now place orders with licensed producers for dried marijuana for in-hospital use by patients. As use of this product increases, hospital pharmacists may have an increased role in the care of patients who are using marijuana for medical purposes. OBJECTIVES: The primary objective of this study was to determine the opinions of hospital pharmacists in Canada regarding marijuana for medical purposes...
March 2016: Canadian Journal of Hospital Pharmacy
https://www.readbyqxmd.com/read/27039369/effects-of-the-great-recession-on-drugs-consumption-in-spain
#6
Nicolau Martin Bassols, Judit Vall Castelló
This paper presents evidence on how the consumption of legal and illegal drugs has changed in response to the Great Recession in Spain. We use a large scale survey from 2005 to 2011 to analyze the association between changes in local economic conditions and drug consumption among individuals aged 15-64. Although Spain was one of the countries hardest hit by the economic downturn, the crisis was unevenly felt across the country. Therefore, we exploit this difference in unemployment rates across provinces to identify the effects of business cycle variations on the consumption of legal and illegal drugs...
September 2016: Economics and Human Biology
https://www.readbyqxmd.com/read/26850063/medical-cannabis-considerations-for-the-anesthesiologist-and-pain-physician
#7
Pierre Beaulieu, Aline Boulanger, Julie Desroches, Alexander J Clark
PURPOSE: New regulations are in place at the federal and provincial levels in Canada regarding the way medical cannabis is to be controlled. We present them together with guidance for the safe use of medical cannabis and recent clinical trials on cannabis and pain. SOURCE: The new Canadian regulations on the use of medical cannabis, the provincial regulations, and the various cannabis products available from the Canadian Licensed Producers were reviewed from Health Canada, provincial licensing authorities, and the licensed producers website, respectively...
May 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/26711860/cannabidiol-induces-rapid-acting-antidepressant-like-effects-and-enhances-cortical-5-ht-glutamate-neurotransmission-role-of-5-ht1a-receptors
#8
Raquel Linge, Laura Jiménez-Sánchez, Leticia Campa, Fuencisla Pilar-Cuéllar, Rebeca Vidal, Angel Pazos, Albert Adell, Álvaro Díaz
Cannabidiol (CBD), the main non-psychotomimetic component of marihuana, exhibits anxiolytic-like properties in many behavioural tests, although its potential for treating major depression has been poorly explored. Moreover, the mechanism of action of CBD remains unclear. Herein, we have evaluated the effects of CBD following acute and chronic administration in the olfactory bulbectomy mouse model of depression (OBX), and investigated the underlying mechanism. For this purpose, we conducted behavioural (open field and sucrose preference tests) and neurochemical (microdialysis and autoradiography of 5-HT1A receptor functionality) studies following treatment with CBD...
April 2016: Neuropharmacology
https://www.readbyqxmd.com/read/26194647/impact-of-a-synthetic-cannabinoid-cp-47-497-c8-on-protein-expression-in-human-cells-evidence-for-induction-of-inflammation-and-dna-damage
#9
Andrea Bileck, Franziska Ferk, Halh Al-Serori, Verena J Koller, Besnik Muqaku, Alexander Haslberger, Volker Auwärter, Christopher Gerner, Siegfried Knasmüller
Synthetic cannabinoids (SCs) are marketed worldwide as legal surrogates for marihuana. In order to predict potential health effects in consumers and to elucidate the underlying mechanisms of action, we investigated the impact of a representative of the cyclohexylphenols, CP47,497-C8, which binds to both cannabinoid receptors, on protein expression patterns, genomic stability and on induction of inflammatory cytokines in human lymphocytes. After treatment of the cells with the drug, we found pronounced up-regulation of a variety of enzymes in nuclear extracts which are involved in lipid metabolism and inflammatory signaling; some of the identified proteins are also involved in the endogenous synthesis of endocannabinoids...
June 2016: Archives of Toxicology
https://www.readbyqxmd.com/read/26178655/cannabis-allergy-what-do-we-know-anno-2015
#10
REVIEW
Ine Decuyper, Hanne Ryckebosch, Athina L Van Gasse, Vito Sabato, Margaretha Faber, Chris H Bridts, Didier G Ebo
For about a decade, IgE-mediated cannabis (marihuana) allergy seems to be on the rise. Both active and passive exposure to cannabis allergens may lead to a cannabis sensitization and/or allergy. The clinical manifestations of a cannabis allergy can vary from mild to life-threatening reactions, often depending on the route of exposure. In addition, sensitization to cannabis allergens can trigger various secondary cross-allergies, mostly for plant-derived food. This clinical entity, which we have designated as the "cannabis-fruit/vegetable syndrome" might also imply cross-reactivity with tobacco, latex and plant-food derived alcoholic beverages...
October 2015: Archivum Immunologiae et Therapiae Experimentalis
https://www.readbyqxmd.com/read/25960036/long-term-consequences-of-perinatal-and-adolescent-cannabinoid-exposure-on-neural-and-psychological-processes
#11
REVIEW
Alejandro Higuera-Matas, Marcos Ucha, Emilio Ambrosio
Marihuana is the most widely consumed illicit drug, even among adolescents and pregnant women. Given the critical developmental processes that occur in the adolescent and fetal nervous system, marihuana consumption during these stages may have permanent consequences on several brain functions in later adult life. Here, we review what is currently known about the long-term consequences of perinatal and adolescent cannabinoid exposure. The most consistent findings point to long-term impairments in cognitive function that are associated with structural alterations and disturbed synaptic plasticity...
August 2015: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/25898704/marihuana-allergy-beyond-the-joint
#12
M Faber, A Van Gasse, V Sabato, M M Hagendorens, Bridts C H, L S De Clerck, D G Ebo
No abstract text is available yet for this article.
2015: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/25697610/-legalization-of-marijuana-the-freedom-that-threatens-public-health
#13
EDITORIAL
V Venegas
No abstract text is available yet for this article.
December 2014: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/25635955/the-effectiveness-of-cannabinoids-in-the-management-of-chronic-nonmalignant-neuropathic-pain-a-systematic-review
#14
REVIEW
Darrell G Boychuk, Greg Goddard, Giovanni Mauro, Maria F Orellana
AIMS: To carry out a systematic review to assess the effectiveness of cannabis extracts and cannabinoids in the management of chronic nonmalignant neuropathic pain. METHODS: Electronic database searches were performed using Medline, PubMed, Embase, all evidence-based medicine reviews, and Web of Science, through communication with the Canadian Consortium for the Investigation of Cannabinoids (CCIC), and by searching printed indices from 1950. Terms used were marijuana, marihuana, cannabis, cannabinoids, nabilone, delta- 9-tetrahydrocannabinol, cannabidiol, ajulemic acid, dronabinol, pain, chronic, disease, and neuropathic...
2015: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/25528919/psychoactive-substances-use-experience-and-addiction-or-risk-of-addiction-among-by-polish-adolescents-living-in-rural-and-urban-areas
#15
Beata Pawłowska, Maciej Zygo, Emilia Potembska, Lucyna Kapka-Skrzypczak, Piotr Dreher, Zbigniew Kędzierski
The objective of the study was to determine the similarities and differences between adolescents with psychoactive substances use experience living in urban and rural areas as regards the intensity of Internet addiction symptoms as well as the evaluation of prevalence of psychoactive substances use among adolescents depending on the place of residence. The examined group consisted of 1 860 people (1 320 girls and 540 boys) their average age being 17 years. In the study the following research methods were used: the Sociodemographic Questionnaire designed by the authors, the Internet Addiction Questionnaire by Potembska, the Internet Addiction test by Young, the Internet Addiction Questionnaire (KBUI) designed by Pawłowska and Potembska...
2014: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/25508539/use-and-medicalization-of-marihuana-in-cancer-patients
#16
Elsa Pedro, Fránces M Rodríguez
Anecdotal reports and some clinical studies suggest that marihuana (Cannabis sativa) is effective in treating a variety of conditions such as glaucoma, migraine, pain, spasticity of multiple sclerosis, anorexia, insomnia, depression, nausea and vomiting. One of the diseases mostly associated to a beneficial effect from marihuana is cancer. Twenty-one states of the United States including the District of Columbia have approved the use of marihuana for cancer and other medical conditions. In Puerto Rico, public debate on criminal penalty removal and medicalization of marihuana has intensified...
2014: Boletín de la Asociación Médica de Puerto Rico
https://www.readbyqxmd.com/read/25470912/use-and-medicalization-of-marihuana-in-cancer-patients
#17
Elsa Pedro, Fránces M Rodríguez
Anecdotal reports and some clinical studies suggest that marihuana (Cannabis sativa) is effective in treating a variety of conditions such as glaucoma, migraine, pain, spasticity of multiple sclerosis, anorexia, insomnia, depression, nausea and vomiting. One of the diseases mostly associated to a beneficial effect from marihuana is cancer. Twenty-one states of the United States including the District of Columbia have approved the use of marihuana for cancer and other medical conditions. In Puerto Rico, public debate on criminal penalty removal and medicalization of marihuana has intensified...
2014: Boletín de la Asociación Médica de Puerto Rico
https://www.readbyqxmd.com/read/25417136/-interpretation-of-the-concept-of-medicinal-product-in-relation-to-herb-and-cannabinoid-based-products
#18
REVIEW
Ferge Zsigmond
On 10th of July 2014 the European Court of Justice made in his decisions in relation to the cases D. (C-358/13) and G. (C-181/14) an interpretation, that the concept of 'medicinal product' according to the law of the European Union does not include the materials, which are - as not covering substances, such as those at issue in the main proceedings, which produce effects that merely modify physiological functions but which are not such as to have any beneficial effects, either immediately or in the long term, on human health, are consumed solely to induce a state of intoxication and are, as such, harmful to human health...
November 30, 2014: Orvosi Hetilap
https://www.readbyqxmd.com/read/25069954/cannabinoid-findings-in-children-hair-what-do-they-really-tell-us-an-assessment-in-the-light-of-three-different-analytical-methods-with-focus-on-interpretation-of-%C3%AE-9-tetrahydrocannabinolic-acid-a-concentrations
#19
Bjoern Moosmann, Nadine Roth, Martin Hastedt, Andrea Jacobsen-Bauer, Fritz Pragst, Volker Auwärter
Hair analysis for drugs and drugs of abuse is increasingly applied in child protection cases. To determine the potential risk to a child living in a household where drugs are consumed, not only can the hair of the parents be analyzed but also the hair of the child. In the case of hair analysis for cannabinoids, the differentiation between external contamination and systemic uptake is particularly difficult, since the drug is quite often handled extensively prior to consumption (e.g. when preparing a joint) and smoke causes a further risk for an external contamination...
May 2015: Drug Testing and Analysis
https://www.readbyqxmd.com/read/24625019/-time-profile-of-serum-thc-levels-in-occasional-and-chronic-marihuana-smokers-after-acute-drog-use-implication-for-drivind-motor-vehicles
#20
Marie Balíková, Tomáš Hložek, Tomáš Páleníček, Filip Tylš, Michaela Viktorinová, Tomáš Melicher, Renáta Androvičová, Pavel Tomíček, Michal Roman, Jiří Horáček
Cannabis consumption has individual influence to cognitive and psychomotor functions of drivers and it has been generally accepted that driving under influence is risky in the perspective of traffic safety. However, rules how to assess fitness to drive are not quite clear. The psychoactive compound delta-9-tetrahydrocannabinol (THC) impairs cognition, psychomotor behaviour and driving performance in a dose-related manner approximately. After a single drug dose, THC blood concentration peaks within minutes, before the end of smoking, with a subsequent rapid decrease to the analytical limit of detection...
2014: Soudní Lékarství
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