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https://www.readbyqxmd.com/read/29745330/metabolism-of-synthetic-cannabinoids-encountered-in-clinical-casework-major-in-vivo-metabolites-of-jwh-007-jwh-019-jwh-203-jwh-307-ur-144-xlr-11-am-2201-mam-2201-and-am-694-in-human-urine-using-lc-ms-ms
#1
Volker Auwarter, Melanie Hutter, S Broecker, Stefan Kneisel, Floria Franz, Simon D Brandt
BACKGROUND: `Herbal mixtures` containing synthetic cannabinoid receptor agonists (SCRAs) are promoted as legal alternative to marihuana and are easily available via the Internet. Keeping analytical methods for the detection of these SCRAs up-to-date is a continuous challenge for clinicians and toxicologists due to the high diversity of the chemical structures and the frequent emergence of new compounds. Since many SCRAs are extensively metabolized, analytical methods used for urine testing require previous identification of the major metabolites of each compound...
May 9, 2018: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/29353295/spanish-version-validation-of-the-marihuana-motives-measure-in-a-drug-consuming-adolescent-sample
#2
Josep Matali Costa, J Simons, M Pardo, M Lleras, A Pérez, O Andión
INTRODUCTION: Cannabis is the illicit drug mostly widely consumed by adolescents in Spain. The understanding of consumption motives is an important factor for intervention. In Spain, there are no available instruments for their evaluation, hence, the goal of this paper is to study the psychometric properties of the Marihuana Motives Measure (MMM) in a sample of adolescent consumers. MATERIAL AND METHOD: Firstly, translation and back-translation was performed. A total of 228 adolescent consumers of cannabis were evaluated...
January 15, 2018: Adicciones
https://www.readbyqxmd.com/read/29353293/alcohol-tobacco-and-cannabis-consumption-in-adolescents-from-a-multicultural-population-burela-lugo
#3
Ainara Díaz Geada, Alicia Busto Miramontes, Francisco Caamaño Isorna
Social inequalities have been associated with morbidity and mortality. Gender, ethnic group and inequalities were studied in an adolescent population to analyze alcohol, tobacco and cannabis consumption. We carried out a cross-sectional study of pupils from high schools in Burela (northern Spain) (n=238). We used the "Factors de Risc en Estudiants de Secundária" questionnaire designed by Agència de Salut Pública de Barcelona. INDEPENDENT VARIABLES: nationality and weekly pocket money...
January 15, 2018: Adicciones
https://www.readbyqxmd.com/read/29325182/-cannabis-in-parkinson-s-disease-hype-or-help
#4
Tina Mainka, Jan Stork, Ute Hidding, Carsten Buhmann
Cannabis buds and extracts as well as synthetic cannabinoids have been available on prescription to patients with severe diseases since March 2017, with the costs covered by health insurance companies.The prescription of medical marihuana is not restricted to specific symptoms and is therefore also valid for patients with Parkinson's disease. From a legal perspective, patients who are seriously ill even have the right to be treated with cannabis if standard treatment methods are unsuccessful or result in unbearable side effects...
February 2018: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/29150215/lifestyles-guide-and-glaucoma-ii-diet-supplements-drugs-sleep-pregnancy-and-systemic-hypertension
#5
A Antón-López, J Moreno-Montañés, S Duch-Tuesta, P Corsino Fernández-Vila, J García-Feijoo, E Millá-Griñó, F J Muñoz-Negrete, L Pablo-Júlvez, I Rodríguez-Agirretxe, J L Urcelay-Segura, F Ussa-Herrera, M P Villegas-Pérez
PURPOSE: To establish evidence based guidelines to advise patients on the relationship between habits, diet, certain circumstances, diseases and glaucoma. METHODS: Review of all published articles on glaucoma and sports or other activities. The papers were classified according to the level of scientific evidence based on the Oxford Centre for Evidence-based Medicine classification. RESULTS: The evidence on the relationship between diet or supplements and the incidence or progression of glaucoma is insufficient to make a general recommendation for glaucoma patients...
February 2018: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/29020729/diagnosing-and-managing-androgen-deficiency-in-men
#6
REVIEW
Raveen Kaur Sandher, Jonathan Aning
Androgens play a crucial role in bone, muscle and fat metabolism, erythropoiesis and cognitive health. In men aged 40-79 years the incidence of biochemical deficiency and symptomatic hypogonadism is 2.1-5.7%. Decreased libido or reduced frequency and quality of erections, fatigue, irritability, infertility or a diminished feeling of wellbeing may be presenting complaints. However, a significant proportion of men with androgen deficiency will be identified when they present for unrelated concerns. Important factors to elicit from the history in addition to the presenting complaint include: a medical history of obesity, type 2 diabetes, systemic diseases or metabolic syndrome which all impact on testosterone physiology...
April 2017: Practitioner
https://www.readbyqxmd.com/read/28957741/cannabis-for-personal-use-in-the-supreme-court-of-mexico-legal-case-and-potential-for-policy-change
#7
Andrés Aguinaco, Aram Barra
No abstract text is available yet for this article.
December 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28921405/cannabis-associated-asthma-and-allergies
#8
REVIEW
J M Chatkin, L Zani-Silva, I Ferreira, N Zamel
Inhalation of cannabis smoke is its most common use and the pulmonary complications of its use may be the single most common form of drug-induced pulmonary disease worldwide. However, the role of cannabis consumption in asthma patients and allergic clinical situations still remains controversial. To review the evidence of asthma and allergic diseases associated with the use of marijuana, we conducted a search of English, Spanish, and Portuguese medical using the search terms asthma, allergy, marijuana, marihuana, and cannabis...
September 18, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/28548193/-therapeutic-potential-of-cannabis-sativa
#9
REVIEW
Marcia Avello L, Edgar Pastene N, Pola Fernández R, Pia Córdova M
Cannabis sativa (marihuana) is considered an illicit drug due to its psychoactive properties. Recently, the Chilean government opened to the use cannabis in the symptomatic treatment of some patients. The biological effects of cannabis render it useful for the complementary treatment of specific clinical situations such as chronic pain. We retrieved scientific information about the analgesic properties of cannabis, using it as a safe drug. The drug may block or inhibit the transmission of nervous impulses at different levels, an effect associated with pain control...
March 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28236096/-cannabis-induced-disorders
#10
REVIEW
M Soyka, U Preuss, E Hoch
Use and misuse of cannabis and marihuana are frequent. About 5% of the adult population are current users but only 1.2% are dependent. The medical use of cannabis is controversial but there is some evidence for improvement of chronic pain and spasticity. The somatic toxicity of cannabis is well proven but limited and psychiatric disorders induced by cannabis are of more relevance, e.g. cognitive disorders, amotivational syndrome, psychoses and delusional disorders as well as physical and psychological dependence...
March 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28120232/molecular-targets-of-the-phytocannabinoids-a-complex-picture
#11
REVIEW
Paula Morales, Dow P Hurst, Patricia H Reggio
For centuries, hashish and marihuana, both derived from the Indian hemp Cannabis sativa L., have been used for their medicinal, as well as, their psychotropic effects. These effects are associated with the phytocannabinoids which are oxygen containing C21 aromatic hydrocarbons found in Cannabis sativa L. To date, over 120 phytocannabinoids have been isolated from Cannabis. For many years, it was assumed that the beneficial effects of the phytocannabinoids were mediated by the cannabinoid receptors, CB1 and CB2...
2017: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/28056357/the-associations-of-adolescents-dating-violence-victimization-well-being-and-engagement-in-risk-behaviors
#12
Joris Van Ouytsel, Koen Ponnet, Michel Walrave
This brief report describes dating violence victimization among adolescents in Flanders, Belgium, and focuses on how dating violence is related to adolescents' well-being and engagement in risk behaviors, such as substance use, sexual behaviors, and engagement in vandalism or fighting. A survey was conducted in Flanders, Belgium among 1187 adolescents (61.3% female, n = 728). A total of 466 respondents between 16 and 22 years old (M = 17.82 years, SD = 0.92) were in a relationship (71.0% female, n = 331), and, therefore, formed the subsample of the present study...
February 2017: Journal of Adolescence
https://www.readbyqxmd.com/read/28000787/establishment-of-a-new-drug-code-for-marihuana-extract-final-rule
#13
(no author information available yet)
The Drug Enforcement Administration is creating a new Administration Controlled Substances Code Number for "Marihuana Extract." This code number will allow DEA and DEA-registered entities to track quantities of this material separately from quantities of marihuana. This, in turn, will aid in complying with relevant treaty provisions. Under international drug control treaties administered by the United Nations, some differences exist between the regulatory controls pertaining to marihuana extract versus those for marihuana and tetrahydrocannabinols...
December 14, 2016: Federal Register
https://www.readbyqxmd.com/read/27975382/evaluating-phytochemical-variation-in-medical-marihuana
#14
E M Mudge, S J Murch, P N Brown
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27749977/working-on-a-standard-joint-unit-a-pilot-test
#15
Cristina Casajuana, Hugo López-Pelayo, María Mercedes Balcells, Laia Miquel, Lídia Teixidó, Joan Colom, Antoni Gual
INTRODUCTION: Assessing cannabis consumption remains complex due to no reliable registration systems. We tested the likelihood of establishing a Standard Joint Unit (SJU) which considers the main cannabinoids with implication on health through a naturalistic approach.  Methodology. Pilot study with current cannabis users of four areas of Barcelona: universities, nightclubs, out-patient mental health service, and cannabis associations. We designed and administered a questionnaire on cannabis use-patterns and determined the willingness to donate a joint for analysis...
July 14, 2017: Adicciones
https://www.readbyqxmd.com/read/27660881/use-of-marijuana-for-medical-purposes
#16
EDITORIAL
Jarosław Pinkas, Piotr Jabłoński, Michal Kidawa, Waldemar Wierzba
Cannabis is the most popular illicit drug on the European market. Over 16 million young Europeans have used it at least once in the last few years. The recent trends in the consumption of marihuana differ between countries. Some countries face an increase in the prevalence of cannabis use, including Poland, where the level cannabis use has been systematically increasing since the 1990's. According to a recent ESPAD study, 19% of Polish adolescents aged 15-16 have used cannabis in the last year. Marihuana is also a leading substance when analyzing the data of seizures and crimes...
September 2016: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/27619556/cannabis-cultivation-in-spain-a-profile-of-plantations-growers-and-production-systems
#17
Arturo Alvarez, Juan F Gamella, Iván Parra
BACKGROUND: The European market for cannabis derivatives is being transformed. The cultivation of cannabis within the EU and the shift of demand from hashish to domestic marihuana are key aspects of this transformation. Spain, formerly central to the trade of Moroccan hashish, is becoming a marihuana-producing country. The emergence of "import-substitution" has been researched in other EU countries, but thus far the Spanish case remains undocumented. METHODS: This paper is based on analysis of data of 748 cannabis plantations seized by Spanish police in 2013...
November 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27590896/cannabis-sativa-allergy-looking-through-the-fog
#18
REVIEW
I I Decuyper, A L Van Gasse, N Cop, V Sabato, M A Faber, C Mertens, C H Bridts, M M Hagendorens, L De Clerck, H P Rihs, D G Ebo
IgE-mediated Cannabis (C. sativa, marihuana) allergy seems to be on the rise. Both active and passive exposure to cannabis allergens may trigger a C. sativa sensitization and/or allergy. The clinical presentation of a C. sativa allergy varies from mild to life-threatening reactions and often seems to depend on the route of exposure. In addition, sensitization to cannabis allergens can result in various cross-allergies, mostly for plant foods. This clinical entity, designated as the 'cannabis-fruit/vegetable syndrome', might also imply cross-reactivity with tobacco, natural latex and plant-food-derived alcoholic beverages...
February 2017: Allergy
https://www.readbyqxmd.com/read/27168633/opinions-of-hospital-pharmacists-in-canada-regarding-marijuana-for-medical-purposes
#19
Fiona Mitchell, Odette Gould, Michael LeBlanc, Leslie Manuel
BACKGROUND: Canada's most recent Marihuana for Medical Purposes Regulations have changed the way in which patients access marijuana. Furthermore, if authorized by the person in charge of the hospital, a pharmacist practising in a hospital may now place orders with licensed producers for dried marijuana for in-hospital use by patients. As use of this product increases, hospital pharmacists may have an increased role in the care of patients who are using marijuana for medical purposes. OBJECTIVES: The primary objective of this study was to determine the opinions of hospital pharmacists in Canada regarding marijuana for medical purposes...
March 2016: Canadian Journal of Hospital Pharmacy
https://www.readbyqxmd.com/read/27039369/effects-of-the-great-recession-on-drugs-consumption-in-spain
#20
Nicolau Martin Bassols, Judit Vall Castelló
This paper presents evidence on how the consumption of legal and illegal drugs has changed in response to the Great Recession in Spain. We use a large scale survey from 2005 to 2011 to analyze the association between changes in local economic conditions and drug consumption among individuals aged 15-64. Although Spain was one of the countries hardest hit by the economic downturn, the crisis was unevenly felt across the country. Therefore, we exploit this difference in unemployment rates across provinces to identify the effects of business cycle variations on the consumption of legal and illegal drugs...
September 2016: Economics and Human Biology
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