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https://www.readbyqxmd.com/read/29458102/%C3%AE-irradiated-chitosan-based-injectable-hydrogels-for-controlled-release-of-drug-montelukast-sodium
#1
Sadaf Hafeez, Atif Islam, Nafisa Gull, Abbas Ali, Shahzad Maqsood Khan, Saba Zia, Kalsoom Anwar, Saba Urooge Khan, Tahir Jamil
Novel pH-sensitive γ-irradiated low molecular weight chitosan (CS) (pre-irradiated) and poly (vinyl alcohol) (PVA) blended injectable hydrogels, crosslinked with varying concentrations of glycerol, were fabricated for drug delivery application. The effect of low molecular weight irradiated CS on controlled drug release was evaluated to address the problem of higher viscosity and lower solubility of high molecular weight CS. The FTIR spectra of hydrogels depicted the presence of all the incorporated functional groups and the developed interactions (physical and chemical)...
February 16, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29458082/beyond-pain-nurses-assessment-of-patient-suffering-dignity-and-dying-in-the-intensive-care-unit
#2
Amanda Su, Lindsay Lief, David Berlin, Zara Cooper, Daniel Ouyang, John Holmes, Renee Maciejewski, Paul K Maciejewski, Holly G Prigerson
CONTEXT: Deaths in the Intensive Care Unit (ICU) are increasingly common in the United States, yet little is known about patients' experiences at the end-of-life in the ICU. OBJECTIVES: The objective of this study was to determine nurse assessment of symptoms experienced, and care received by ICU patients in their final week, and their associations with nurse-perceived suffering and dignity. METHODS: From September 2015 to March 2017, nurses who cared for 200 ICU patients who died were interviewed about physical and psychosocial dimensions of patients' experiences...
February 16, 2018: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29457580/food-and-beverage-intakes-according-to-physical-activity-levels-in-european-children-the-idefics-identification-and-prevention-of-dietary-and-lifestyle-induced-health-effects-in-children-and-infants-study
#3
Alba M Santaliestra-Pasías, Jaime E Llamas Dios, Ole Sprengeler, Antje Hebestreit, Stefaan De Henauw, Gabriele Eiben, Regina Felsö, Fabio Lauria, Michael Tornaritis, Toomas Veidebaum, Valeria Pala, Luis A Moreno
OBJECTIVE: Physical activity (PA) levels and dietary habits are considered some of the most important factors associated with obesity. The present study aimed to examine the association between PA level and food and beverage consumption in European children (2-10 years old). Design/Setting/Subjects A sample of 7229 children (49·0 % girls) from eight European countries participating in the IDEFICS (Identification and prevention of Dietary and lifestyle induced health EFfects In Children and infantS) study was included...
February 19, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29457538/effects-of-dexmedetomidine-infusion-during-spinal-anesthesia-on-hemodynamics-and-sedation
#4
Ebru Tarıkçı Kılıç, Gaye Aydın
We evaluated the effects of intravenous dexmedetomidine during spinal anesthesia on hemodynamics, respiratory rate, oxygen saturation, sedpain, and compared them with those of saline infusion. Sixty American Society of Anesthesiologists physical status I and II cases were randomly divided into two groups. Patients were connected to the monitor after premedication, and spinal anesthesia was administered. Sensory and motor blockades were assessed using pinprick test and Bromage scale, respectively. Group I received dexmedetomidine infusion and Group II received saline infusion...
December 2018: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/29457369/internet-searches-for-affect-related-terms-an-indicator-of-subjective-well-being-and-predictor-of-health-outcomes-across-us-states-and-metro-areas
#5
Michael T Ford, Andrew T Jebb, Louis Tay, Ed Diener
BACKGROUND: The present study explored the potential for internet search data to serve as indicators of subjective well-being (SWB) and predictors of health at the state and metro area levels. We propose that searches for positive and negative affect-related terms represent information-seeking behavior of individuals who are experiencing emotions and seeking information about them. METHOD: Data on the frequency of Google searches for 15 affect terms were collected from Google's Trends website (trends...
February 18, 2018: Applied Psychology. Health and Well-being
https://www.readbyqxmd.com/read/29457326/associations-between-adolescent-risk-for-restrictive-disordered-eating-and-long-term-outcomes-related-to-somatic-symptoms-body-mass-index-and-poor-well-being
#6
Evelina Landstedt, Anne Hammarström, A Kate Fairweather-Schmidt, Tracey Wade
OBJECTIVE: To date, no longitudinal, community-based studies have examined the association between disordered eating emerging in adolescence and long-term physical well-being. This study sought to explore the longitudinal associations between risk for restrictive disordered eating (DE-R; those not presenting with binge-purge symptoms) in adolescence and trajectories of functional somatic symptoms (FSS) and body mass index (BMI), and several indicators of poor physical well-being across early- to mid-adulthood, including medication, number of doctor visits, and sick leave...
February 18, 2018: British Journal of Health Psychology
https://www.readbyqxmd.com/read/29456706/comparison-of-single-and-triple-injection-methods-for-ultrasound-guided-interscalene-brachial-plexus-blockade
#7
Cun-Jin Wang, Ya-Li Ge, Ju Gao, Feng-Yun Long, Zhi-Hua Mi, Tian-Feng Huang, Xiang-Zhi Fang, Xiao-Ping Chen, Yu-Si Hua, Yang Zhang
Ultrasound-guided interscalene brachial plexus blockade (IBPB) has a relatively high success rate in shoulder surgery; however, whether multiple injections are superior to a single injection (SI) is currently unknown. In the present study, ultrasound-guided SI and triple-injection (TI) IBPBs were compared in a prospective randomized trial. A total of 111 patients undergoing arthroscopic shoulder surgery and presenting with an American Society of Anesthesiologists physical status grading of I-II were randomly allocated to receive IBPB with 15 ml of 1% ropivacaine as a SI or TI...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29456700/effects-of-hiv-on-metabolic-and-biological-pathways-of-cd4-t-lymphocytes
#8
Yanli Ma, Wenge Zhao, Changhe Shi, Ning Wang, Tianli Fan
The effects of human immunodeficiency virus (HIV) on the metabolic and biological pathways of cluster of differentiation (CD)4+ T lymphocytes were investigated. A total of 150 patients with acquired immune deficiency syndrome (AIDS) and 50 healthy individuals who were admitted to hospital for physical examination during the period of June 2016 to January 2017, were selected as subjects in the present study. According to the virus load, 150 AIDS patients were divided into three groups: i) Viral load >106 copies/ml (group A, n=39), ii) 104 copies/ml < viral load <105 copies/ml (group B, n=76), and iii) viral load <104 copies/ml (group C, n=35)...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29456588/a-survey-of-caregiver-burden-in-those-providing-informal-care-for-patients-with-schizophrenia-or-bipolar-disorder-with-agitation-results-from-a-european-study
#9
Sophee Blanthorn-Hazell, Alfredo Gracia, Jenna Roberts, Anca Boldeanu, Davneet Judge
Background: Agitation is a common feature of bipolar disorder and schizophrenia. Previous research indicates that specific symptoms impact caregiver burden in these conditions, but the impact of agitation on caregiver experience is poorly understood. The aim of this study was to characterise caregiver burden in providers of informal care for patients with bipolar disorder and schizophrenia who experience agitation. Methods: In total, 297 matched patient and caregiver surveys were collected across the UK, Germany and Spain between October 2016 and January 2017...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29456456/developing-and-evaluating-an-instrument-to-measure-recovery-after-intensive-care-the-rain-instrument
#10
Ingegerd Bergbom, Veronika Karlsson, Mona Ringdal
Background: Measuring and evaluating patients' recovery, following intensive care, is essential for assessing their recovery process. By using a questionnaire, which includes spiritual and existential aspects, possibilities for identifying appropriate nursing care activities may be facilitated. The study describes the development and evaluation of a recovery questionnaire and its validity and reliability. Methods: A questionnaire consisting of 30 items on a 5-point Likert scale was completed by 169 patients (103 men, 66 women), 18 years or older (m=69, SD 12...
2018: BMC Nursing
https://www.readbyqxmd.com/read/29456447/a-preliminary-analysis-of-outcomes-and-end-range-procedures-used-to-achieve-centralization-in-people-with-low-back-pain
#11
Thomas Stowell, Ronald Schenk, Madeleine Hellman, Carlos Ladeira
Objectives: To investigate the relationship between clinical outcome and the types of end range procedures used to achieve centralization in a sample of patients with low back pain (LBP) and/or peripheral symptoms. Methods: Small sample retrospective analysis of an observational cohort. Patients with LBP who centralized during initial visit at two physical therapy clinics were recruited to participate. The types of end range procedures used to achieve centralization were documented during each office visit and a chart review was performed after 4 weeks...
February 2018: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/29456446/prevalence-and-reliability-of-treatment-based-classification-for-subgrouping-patients-with-low-back-pain
#12
Isadora Orlando de Oliveira, Rodrigo Antunes de Vasconcelos, Bruna Pilz, Paulo Eduardo Portes Teixeira, Eduarda de Faria Ferreira, Wilson Mello, Débora Bevilaqua Grossi
Objectives: To observe the distribution of patients who presented with low back pain (LBP) and to determine the between therapists' interrater reliability of assessments in a private outpatient setting using treatment-based classification (TBC) subgroups. Methods: An observational and methodological study was conducted. Four hundred and twenty-nine patients (231 male; 198 female) presenting LBP symptoms and referred to conservative treatment were assessed by 13 physical therapists who conducted a 60-min examination process utilizing TBC subgroups...
February 2018: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/29456443/the-screening-process-of-a-patient-with-low-back-pain-and-suspected-thoracic-myelopathy-a-case-report
#13
Guillaume Christe, Toby Hall
Background: Thoracic disc herniations are rare and difficult to diagnose. Myelopathy is a potential consequence that can lead to irreversible neurological impairment if not treated appropriately. It is incumbent on all clinicians who see patients with low back pain (LBP) to be aware of such pathologies. This case describes a screening process in the detection of a rare serious spinal pathology and discusses the use of red flags and central nervous system signs and symptoms in the decision leading to immediate referral...
February 2018: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/29456442/the-effect-of-direction-specific-thoracic-spine-manipulation-on-the-cervical-spine-a-randomized-controlled-trial
#14
Steve Karas, Megan J Olson Hunt, Bill Temes, Martin Thiel, Trenton Swoverland, Brett Windsor
Objectives: To determine the difference on neck outcomes with directional manipulation to the thoracic spine. There is evidence that thoracic spine manipulation is effective in treating patients with neck pain. However, there is no research that determines if the assessment of directional hypomobility and the selection of thrust direction offer improved outcomes. Methods: A total of 69 patients with cervical spine pain were randomly assigned to receive either a manipulation that was consistent with their thoracic spine motion loss (matched) or opposite their motion loss (unmatched)...
February 2018: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/29456379/assessment-of-health-related-quality-of-life-among-asthmatic-patients-the-need-for-structured-pharmaceutical-care-delivery-system-in-pakistan
#15
Madeeha Malik, Adeela Khan, Azhar Hussain, Ayisha Hashmi
Asthma is considered as one of the most common chronic diseases in the world. As a result of serious physical, social, and psychological complications, asthma can reduce health-related quality of life (HRQoL). The present study was designed to assess the HRQoL including physical health, general health perception, emotional health, psychological health, and social functioning of asthmatic patients in Pakistan. A descriptive cross-sectional study design was used. Setting was public and private healthcare facilities...
October 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29456348/efficacy-of-dexmedetomidine-as-an-adjuvant-to-local-anesthetic-agent-in-scalp-block-and-scalp-infiltration-to-control-postcraniotomy-pain-a-double-blind-randomized-trial
#16
Shankar Vallapu, Nidhi Bidyut Panda, Navneh Samagh, Neerja Bharti
Context: Scalp infiltration and scalp block are being used to manage postcraniotomy pain. Dexmedetomidine has been successfully used as an adjuvant in regional anesthesia. The study was intended to compare whether addition of dexmedetomidine prolonged the duration of analgesia as well as to compare the two techniques. Aims: The primary objective was to assess whether addition of dexmedetomidine to bupivacaine prolonged the duration of analgesia. The secondary objective was to compare between scalp nerve block and scalp infiltration as techniques for pain relief...
January 2018: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29456067/revision-hip-arthroscopy-after-labral-reconstruction-using-iliotibial-band-autograft-surgical-findings-and-comparison-of-outcomes-with-labral-reconstructions-not-requiring-revision
#17
Renato Locks, Ioanna K Bolia, Hajime Utsunomiya, Karen K Briggs, Marc J Philippon
PURPOSE: To determine the causes of revision hip arthroscopy in patients who underwent labral reconstruction and to compare outcomes of these patients with patients who did not require a revision following reconstruction. METHODS: Patients who underwent revision hip arthroscopy after previous labral reconstruction from 2006 to 2014 were included. Patients with less than 2-year follow-up, preoperative joint space of ≤2 mm, or who underwent other reconstructive procedures at the time of labral reconstruction were excluded...
February 15, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29455997/effect-of-dynamic-high-pressure-on-emulsifying-and-encapsulant-properties-of-cashew-tree-gum
#18
Bruna Castro Porto, Marcelo Cristianini
Dynamic high pressure (DHP) has been applied in the physical modification of biopolymers as polysaccharides, proteins and gums. It is known that DHP is able to promote degradation of polysaccharides (e.g. molecular weight reduction). However, few studies have assessed the effect of DHP on the emulsifying and encapsulating properties of polysaccharides. Thus, this study aimed to investigate the effect of DHP on the emulsifying (average droplet size and particle size distribution, optical and confocal scanning laser microscopy, rheology, zeta potential and electric conductivity, creaming index, and turbidity) and encapsulating (scanning electronic microscopy, flavor retention, average droplet size, and particle size distribution) properties of cashew tree gum (CG)...
April 15, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29455901/prevalence-of-mental-disorders-and-related-functioning-and-treatment-engagement-among-people-with-diabetes
#19
Matthew Tyler Boden
AIMS: To examine prevalence, functioning and treatment associated with all DSM-5 12-month mood, anxiety, eating and substance use disorders among people with diabetes in data obtained from the National Epidemiologic Survey on Alcohol and Related Conditions-III. METHODS: Through multistage stratified randomized sampling a sample representative of the United States civilian population was obtained. Prevalence of diabetes (Type 1 and 2), DSM-5 disorders, physical and mental functioning, and treatment utilization were assessed via telephone interview...
March 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29455894/cognitive-behavioural-therapy-for-ms-related-fatigue-explained-a-longitudinal-mediation-analysis
#20
L E van den Akker, H Beckerman, E H Collette, H Knoop, G Bleijenberg, J W Twisk, J Dekker, V de Groot
BACKGROUND: Cognitive behavioural therapy (CBT) effectively reduces fatigue directly following treatment in patients with Multiple Sclerosis (MS), but little is known about the process of change during and after CBT. DESIGN: Additional analysis of a randomized clinical trial. OBJECTIVE: To investigate which psychological factors mediate change in fatigue during and after CBT. METHODS: TREFAMS-CBT studied the effectiveness of a 16-week CBT treatment for MS-related fatigue...
March 2018: Journal of Psychosomatic Research
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