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https://www.readbyqxmd.com/read/28550797/potential-tracers-for-tracking-septic-tank-effluent-discharges-in-watercourses
#1
Samia Richards, Paul J A Withers, Eric Paterson, Colin W McRoberts, Marc Stutter
Septic tank effluent (STE) contributes to catchment nutrient and pollutant loads. To assess the role of STE discharges in impairment of surface water, it is essential to identify the sources of pollution by tracing contaminants in watercourses. We examined tracers that were present in STE to establish their potential for identifying STE contamination in two stream systems (low and high dilution levels) against the background of upstream sources. The studied tracers were microbial, organic matter fluorescence, caffeine, artificial sweeteners and effluent chemical concentrations...
May 24, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28550718/attachment-to-place-in-advanced-age-a-study-of-the-lilacs-nz-cohort
#2
Janine L Wiles, Anna Rolleston, Avinesh Pillai, Joanna Broad, Ruth Teh, Merryn Gott, Ngaire Kerse
An extensive body of research theorises that attachment to place is positively associated with health, particularly for older people. Building on this, we measure how indicators of attachment to place are associated with health for in people of advanced age in New Zealand. We use data from a cohort study (LiLACS NZ), which includes an indigenous Māori cohort aged 80-90 years and a non-Māori cohort aged 85 years from a mixed urban/rural region in New Zealand. Each cohort undertook a comprehensive interview and health assessment (n = 267 Māori and n = 404 non-Māori)...
May 4, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28550685/long-noncoding-rna-camta1-promotes-proliferation-and-mobility-of-human-breast-cancer-cell-line-mda-mb-231-via-targeting-mir-20b
#3
Pengwei Lu, Yuanting Gu, Lin Li, Fang Wang, Xue Yang, Yunqing Yang
Breast cancer is a serious threat to women's physical and psychological health. Long non-coding RNA CAMTA1 (LncCAMTA1)was believed to be related with tumor progression, but its role in breast cancer is not clear. Human breast cancer cell line MDA-MB-231 was used to investigate effect of LncCAMTA1 on cell viability, migration/invasion, and apoptosis. Expression of LncCAMTA1, miR-20b and VEGF in MDA-MB-231were measured after corresponding transfections. Binding effects between LncCAMTA1 and miR-20b, miR-20b and VEGF 3'UTR were measured...
May 21, 2017: Oncology Research
https://www.readbyqxmd.com/read/28550489/impedance-ph-monitoring-for-diagnosis-of-reflux-disease-new-perspectives
#4
REVIEW
Marzio Frazzoni, Nicola de Bortoli, Leonardo Frazzoni, Salvatore Tolone, Vincenzo Savarino, Edoardo Savarino
Heartburn is the most specific symptom of gastroesophageal reflux disease (GERD). In clinical practice, heartburn relief by a proton pump inhibitor (PPI) trial does suffice to confirm GERD. However, an objective diagnosis of GERD is required before anti-reflux endoscopic or surgical interventions, independently from PPI response. Thus, since normal findings at upper endoscopy are detected in the majority of patients with heartburn, reflux monitoring is often required. When traditional catheter-based or wireless pH tests are used, reflux episodes are conventionally identified by pH drops below 4...
May 26, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28550403/healthcare-utilization-and-costs-in-ards-survivors-a-1-year-longitudinal-national-us-multicenter-study
#5
A Parker Ruhl, Minxuan Huang, Elizabeth Colantuoni, Taruja Karmarkar, Victor D Dinglas, Ramona O Hopkins, Dale M Needham
PURPOSE: To evaluate (1) post-discharge healthcare utilization and estimated costs in ARDS survivors, and (2) the association between patient and intensive care-related variables, and 6-month patient status, with subsequent hospitalization and costs. METHODS: Longitudinal cohort study enrolling from four ARDSNet trials in 44 US hospitals. Healthcare utilization was collected via structured interviews at 6 and 12 months post-ARDS, and hospital costs estimated via the Medical Expenditure Panel Survey...
May 26, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28550009/digital-support-interventions-for-the-self-management-of-low-back-pain-a-systematic-review
#6
Barbara I Nicholl, Louise F Sandal, Mette J Stochkendahl, Marianne McCallum, Nithya Suresh, Ottar Vasseljen, Jan Hartvigsen, Paul J Mork, Per Kjaer, Karen Søgaard, Frances S Mair
BACKGROUND: Low back pain (LBP) is a common cause of disability and is ranked as the most burdensome health condition globally. Self-management, including components on increased knowledge, monitoring of symptoms, and physical activity, are consistently recommended in clinical guidelines as cost-effective strategies for LBP management and there is increasing interest in the potential role of digital health. OBJECTIVE: The study aimed to synthesize and critically appraise published evidence concerning the use of interactive digital interventions to support self-management of LBP...
May 21, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28549923/maintaining-vitamin-d-sufficiency-is-associated-with-improved-structural-and-symptomatic-outcomes-in-knee-osteoarthritis
#7
Shuang Zheng, Xingzhong Jin, Flavia Cicuttini, Xia Wang, Zhaohua Zhu, Anita Wluka, Weiyu Han, Tania Winzenberg, Benny Antony, Dawn Aitken, Leigh Blizzard, Graeme Jones, Changhai Ding
BACKGROUND: To describe whether maintaining sufficient serum vitamin D levels in people with knee osteoarthritis and baseline vitamin D insufficiency has an association with change in knee structures and symptoms over two years. METHODS: Participants (n=413, age 63.2) with symptomatic knee osteoarthritis and vitamin D insufficiency were enrolled in a clinical trial. 340 participants (82.3%) completed the study with 25-hydroxyvitamin D [25(OH)D] measurements at month 0, 3 and 24...
May 23, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28549907/transformation-of-bcs-class-i-and-iii-drugs-into-ionic-liquids-and-lipophilic-salts-for-enhanced-developability-using-lipid-formulations
#8
Hywel D Williams, Leigh Ford, Shea Lim, Sifei Han, John Baumann, Hannah Sullivan, David Vodak, Annabel Igonin, Hassan Benameur, Colin W Pouton, Peter J Scammells, Christopher J H Porter
Higher lipid solubility of lipophilic salt forms creates new product development opportunities for high-dose liquid-filled capsules. The purpose of this study was to determine if lipophilic salts of BCS Class I amlodipine and BCS Class III fexofenadine, ranitidine and metformin were better lipid formulation candidates than existing commercial salts. Lipophilic salts were prepared from lipophilic anions and commercial HCl or besylate salt forms, as verified by (1)H NMR. Thermal properties were assessed by DSC and hot-stage microscopy...
May 23, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28549846/physical-activity-and-age-related-macular-degeneration-a-systematic-literature-review-and-meta-analysis
#9
Myra B McGuinness, Jerome Le, Paul Mitchell, Bamini Gopinath, Ester Cerin, Nicole T M Saksens, Tina Schick, Carel B Hoyng, Robyn H Guymer, Robert P Finger
PURPOSE: Age-related macular degeneration (AMD) is the main cause of irreversible severe vision loss in developed countries. It has been suggested that a healthy lifestyle may assist in delaying the onset and progression of AMD, however evidence for an association between physical activity and age-related macular degeneration (AMD) remains inconclusive. DESIGN: Systematic review and meta-analysis METHODS: Medline, EMBASE and Google Scholar were systematically searched for studies up to May 2015...
May 23, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28549839/vitamin-b12-deficiency-might-be-related-to-sarcopenia-in-older-adults
#10
Esra Ates Bulut, Pinar Soysal, Ali Ekrem Aydin, Ozge Dokuzlar, Suleyman Emre Kocyigit, Ahmet Turan Isik
Sarcopenia and dynapenia are related to repeated falls, mobility restriction, depression, frailty, increased mortality and morbidity. The aim of this study is to evaluate the relationship between vitamin B12 deficiency and sarcopenia in older adults. 403 patients, who attended to outpatient clinic and underwent comprehensive geriatric assessment, were included study. All cases' skeletal muscle mass (SMM), walking speed and hand grip strength were recorded by bioimpedance, 4meter walking test and hand dynamometer respectively...
May 23, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28549753/correlations-between-impairment-psychological-distress-disability-and-quality-of-life-in-peripheral-facial-palsy
#11
U Díaz-Aristizabal, M Valdés-Vilches, T R Fernández-Ferreras, E Calero-Muñoz, E Bienzobas-Allué, T Moracén-Naranjo
INTRODUCTION: This paper analyses the correlations between scores on scales assessing impairment, psychological distress, disability, and quality of life in patients with peripheral facial palsy (PFP). MATERIAL AND METHODS: We conducted a retrospective cross-sectional study including 30 patients in whom PFP had not resolved completely. We used tools for assessing impairment (Sunnybrook Facial Grading System [FGS]), psychological distress (Hospital Anxiety and Depression Scale [HADS]), disability (Facial Disability Index [FDI]), and quality of life (Facial Clinimetric Evaluation [FaCE] scale)...
May 23, 2017: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/28549711/symptomatic-lumbar-facet-synovial-cysts-clinical-outcomes-following-percutaneous-ct-guided-cyst-rupture-with-intraarticular-steroid-injection
#12
Steffen J Haider, Nu R Na, Clifford J Eskey, Jessica G Fried, Natalie Y Ring, Mike H Bao, David A Pastel
PURPOSE: To evaluate clinical outcomes following percutaneous rupture of symptomatic lumbar facet synovial cysts (LFSCs) with intraarticular steroid injection. MATERIALS AND METHODS: In this retrospective review, 44 consecutive patients with symptomatic LFSCs received primary treatment with CT-guided synovial cyst rupture with intraarticular steroid injection. Outcomes questionnaires were obtained before and 1, 4, 26, and 52 weeks after LFSC rupture. Assessment included pain medication use and numeric rating scale (NRS), Oswestry Disability Index (ODI), and 12-item short form health survey (SF-12) physical and mental composite scores (PCS and MCS)...
May 24, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28549707/interventions-for-treating-sarcopenia-a-systematic-review-and-meta-analysis-of-randomized-controlled-studies
#13
Yoshihiro Yoshimura, Hidetaka Wakabayashi, Minoru Yamada, Hunkyung Kim, Atsushi Harada, Hidenori Arai
BACKGROUND: Much interest has been focused on interventions for treating sarcopenia; however, the effects have gained little evidence. OBJECTIVE: To analyze the effectiveness of exercise, nutritional, drug, and combinational interventions for treating sarcopenia in older people. METHOD: We systematically searched MEDLINE via PubMed, the Cochrane Library of Cochrane Reviews and Cochrane Central Register of Controlled Trials, and Ichushi-Web for randomized controlled trials (RCTs) from January 2000 to December 2016...
June 1, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28549634/maternal-adverse-childhood-experience-and-infant-health-biomedical-and-psychosocial-risks-as-intermediary-mechanisms
#14
Sheri Madigan, Mark Wade, Andre Plamondon, Jonathon L Maguire, Jennifer M Jenkins
OBJECTIVE: To assess the mechanisms accounting for the transfer of risk from one generation to the next, especially as they relate to maternal adverse childhood experiences and infant physical and emotional health outcomes. STUDY DESIGN: Participants were 501 community mother-infant dyads recruited shortly after the birth and followed up at 18 months. Mothers retrospectively reported on their adverse childhood experiences. The main outcome measures were parent-reported infant physical health and emotional problems...
May 23, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28549476/comparing-motivational-self-regulatory-and-habitual-processes-in-a-computer-tailored-physical-activity-intervention-in-hospital-employees-protocol-for-the-paths-randomised-controlled-trial
#15
Dominika Kwasnicka, Corneel Vandelanotte, Amanda Rebar, Benjamin Gardner, Camille Short, Mitch Duncan, Dawn Crook, Martin S Hagger
BACKGROUND: Most people do not engage in sufficient physical activity to confer health benefits and to reduce risk of chronic disease. Healthcare professionals frequently provide guidance on physical activity, but often do not meet guideline levels of physical activity themselves. The main objective of this study is to develop and test the efficacy of a tailored intervention to increase healthcare professionals' physical activity participation and quality of life, and to reduce work-related stress and absenteeism...
May 26, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28549469/are-children-participating-in-a-quasi-experimental-education-outside-the-classroom-intervention-more-physically-active
#16
Mikkel Bo Schneller, Scott Duncan, Jasper Schipperijn, Glen Nielsen, Erik Mygind, Peter Bentsen
BACKGROUND: Education outside the classroom (EOtC) is a curriculum-based approach to teaching that has shown positive associations with children's physical activity and academic learning in small-scale case studies. The purpose of this large-scale quasi-experimental study was to determine if children who participate regularly in EOtC spend more time being physically active than children who do not. METHODS: In the 2014/2015 study TEACHOUT, classes were recruited in pairs such that each EOtC class had a non-EOtC comparison class at the same school and grade level...
May 26, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28549317/frontal-and-subcortical-grey-matter-reductions-in-ptsd
#17
Daniel C M O'Doherty, Ashleigh Tickell, Will Ryder, Charles Chan, Daniel F Hermens, Maxwell R Bennett, Jim Lagopoulos
Post-traumatic stress disorder (PTSD) is characterised by a range of debilitating psychological, physical and cognitive symptoms. PTSD has been associated with grey matter atrophy in limbic and frontal cortical brain regions. However, previous studies have reported heterogeneous findings, with grey matter changes observed beyond limbic/frontal areas. Seventy-five adults were recruited from the community, 25 diagnosed with PTSD along with 25 healthy and 25 trauma exposed age and gender matched controls. Participants underwent clinical assessment and magnetic resonance imaging...
May 19, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28549180/relationships-among-self-perception-of-aging-physical-functioning-and-self-efficacy-in-late-life
#18
Hava Tovel, Sara Carmel, Victoria H Raveis
Objectives: The purpose of the current study was to examine the longitudinal relationship between 2 central concepts in the study of subjective well-being in old age-self-perception of aging (SPA) and physical functioning, and to assess the mediating role of self-efficacy beliefs in this relationship. Methods: Interviews were conducted in the home with 1,216 randomly selected persons aged 75+ years (T1) and repeated with 892 of them 2 years later (T2). We collected data on SPA, physical functioning, self-efficacy, self-rated health, and demographics...
May 25, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28549046/associations-of-physical-fitness-and-body-composition-characteristics-with-simulated-military-task-performance
#19
K Pihlainen, M Santtila, K Häkkinen, H Kyröläinen
The purpose of the present study was to evaluate the associations of physical fitness and body composition characteristics with anaerobic endurance performance, tested in the combat load using the occupationally relevant military simulation test (MST). Eighty-one male soldiers, deployed to a crisis management operation in the Middle East, volunteered for the study and participated in a test battery consisting measurements of muscle strength, body composition characteristics, endurance capacity, and MST.A Spearman correlational analysis revealed that the strongest variable, correlated with MST time, was the countermovement jump performed with the combat load (CMJ2) (rs = -0...
May 25, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28548972/assessment-of-adult-malnutrition-and-prognosis-with-bioelectrical-impedance-analysis-phase-angle-and-impedance-ratio
#20
Henry C Lukaski, Ursula G Kyle, Jens Kondrup
PURPOSE OF REVIEW: Malnutrition affects prognosis in many groups of patients. Although screening tools are available to identify adults at risk for poor nutritional status, a need exists to improve the assessment of malnutrition by identifying the loss of functional tissues that can lead to frailty, compromised physical function, and increased risk of morbidity and mortality, particularly among hospitalized and ill patients and older adults. Bioimpedance analysis (BIA) offers a practical approach to identify malnutrition and prognosis by assessing whole-body cell membrane quality and depicting fluid distribution for an individual...
May 25, 2017: Current Opinion in Clinical Nutrition and Metabolic Care
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