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https://www.readbyqxmd.com/read/28547533/sensitivity-and-specificity-of-optical-coherence-tomography-angiography-oct-a-for-detection-of-choroidal-neovascularization-in-real-life-practice-and-varying-retinal-expertise-level
#1
Vaël Souedan, Eric H Souied, Violaine Caillaux, Alexandra Miere, Ala El Ameen, Rocio Blanco-Garavito
PURPOSE: To evaluate the diagnostic accuracy of OCT angiography (OCT-A) detecting or predicting choroidal neovascularization (CNV), by ophthalmologists of disparate degrees of skills in retinal diseases, using spectral domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA) as a standard reference. METHODS: Retrospective observational case series. Patient presenting maculopathy and complete imaging were included. FA, SD-OCT, OCT-A and FA coupled to SD-OCT images were graded independently for presence or absence of CNV by ophthalmologists with varying expertise levels...
May 25, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28546939/demographic-features-and-visual-outcomes-of-patients-presenting-to-diabetic-photo-screening-and-treated-for-sight-threatening-retinopathy-in-fiji
#2
Riyaz Bhikoo, Neil Murray, Biu Sikivou, Stephanie Emma, Charles McGhee
AIM: To describe the demographic features and visual outcomes of patients presenting to photo-screening services, and treated for sight threatening retinopathy (STR) in a low resource setting, Fiji. METHODS: A retrospective review of all new patients who presented for diabetic photo-screening at the Diabetic Eye Clinic, Suva in 2010. Fundus images were graded using standardised guidelines. Patient demographics, retinopathy grading and visual acuity data were extracted from the database and analyzed...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28542922/study-of-retinal-neurodegeneration-and-maculopathy-in-diabetic-meriones-shawi-a-particular-animal-model-with-human-like-macula
#3
Imane Hammoum, Maha Benlarbi, Ahmed Dellaa, Klaudia Szabó, Bulcsú Dékány, Dávid Csaba, Zsuzsanna Almási, Rozina I Hajdú, Rached Azaiz, Ridha Charefeddine, Ákos Lukáts, Rafika Benchouacha-Chekir
The purpose of this work was to evaluate a potentially useful animal model, Meriones shawi (M.sh) - developing metabolic X syndrome, diabetes and possessing a visual streak similar to human macula - in the study of diabetic retinopathy and diabetic macular edema (DME). Type 2 diabetes (T2D) was induced by high fat diet administration in M.sh. Body weights, blood glucose levels were monitored throughout the study. Diabetic retinal histopathology was evaluated 3 and 7 months after diabetes induction. Retinal thickness was measured, retinal cell types were labeled by immunohistochemistry and the number of stained elements were quantified...
May 20, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28538221/retinal-microvasculature-in-nonproliferative-diabetic-retinopathy-automated-quantitative-optical-coherence-tomography-angiography-assessment
#4
Marco Lupidi, Gabriel Coscas, Florence Coscas, Tito Fiore, Elisa Spaccini, Daniela Fruttini, Carlo Cagini
PURPOSE: To perform a qualitative and quantitative assessment of the foveal microvasculature in eyes with diabetic maculopathy using optical coherence tomography angiography (OCT-A). METHODS: Retrospective case series of 48 eyes with diabetic maculopathy and 47 healthy eyes evaluated by Spectralis OCT-A. Perifoveal arcade disruptions, linear vascular dilations, microaneurysms, intraretinal microvascular abnormalities and flow-void areas were qualitatively analyzed on OCT angiograms both for the superficial (SCP) and deep (DCP) capillary plexuses...
May 25, 2017: Ophthalmic Research
https://www.readbyqxmd.com/read/28532619/traumatic-cyclodialysis-treated-with-transscleral-ciclodiode-laser-anterior-and-posterior-segment-evolution
#5
J González-Martín-Moro, M Castro-Rebollo, J Zarallo-Gallardo, F J Muñoz-Negrete
CASE REPORT: A 35-year-old man suffered a severe hipotension maculopathy after being kicked in his left eye. He presented a broad area of iridodialisis. Gonioscopy, ultrasound biomicroscopy and optic coherence tomography were not able to locate the suspected cyclodialysis. Medical treatment was ineffective. Five months later the patient received transcleral diode laser cyclophotocoagulation with clinical resolution. DISCUSSION: Transscleral diode laser constitutes an effective treatment, with low iatrogenia, that can solve cases of ocular hypotension, even when the location of the cyclodialysis has not been determined...
May 19, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28525681/unveiling-idiopathic-macular-telangiectasia-clinical-applications-of-optical-coherence-tomography-angiography
#6
Marco A Gonzalez, Diana Shechtman, Jay M Haynie, Leo Semes
PURPOSE: Idiopathic macular telangiectasia type 2 (IMT2) is a bilateral acquired maculopathy, with a spectrum of clinical presentations associated with inner retinal telangiectatic vascular anomalies. Cases often are underdiagnosed or misdiagnosed. Current diagnostic modalities such as spectral-domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA) are valuable to the understanding of the clinicopathology. More recently, optical coherence tomography angiography (OCTA), as an emerging noninvasive technology, has been shown to be particularly useful in the assessment and management of IMT2...
May 19, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28524715/prevalence-of-age-related-macular-degeneration-in-slovakia-and-associated-risk-factors-a-mobile-clinic-based-cross-sectional-epidemiological-survey
#7
Vladimir Krasnik, Jana Stefanickova, Ivajlo Popov, Jela Valaskova, Sandeep Saxena, Peter Kruzliak
PURPOSE: Age-related macular degeneration (AMD) is one of the leading causes of blindness in the elderly population. Although there are prevalence studies for AMD in Europe, data are scarce for the Slovakian population. METHODS: This was a prospective, multicenter, non-interventional, mobile clinic-based cross-sectional study that assessed age-specific prevalence of AMD in the Slovakian population and risk factors associated with AMD. The type of AMD was graded based on the international age-related maculopathy grading system; optical coherence tomography (OCT) was used for the differential diagnosis...
May 19, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28520626/multimodal-imaging-of-acute-exudative-polymorphous-vitelliform-maculopathy-with-optical-coherence-tomography-angiography-and-adaptive-optics-scanning-laser-ophthalmoscopy
#8
Dimitra Skondra, Peter L Nesper, Amani A Fawzi
PURPOSE: To report a case of acute exudative polymorphous vitelliform maculopathy including the findings of optical coherence tomography angiography and adaptive optics scanning laser ophthalmoscopy. METHODS: Findings on clinical examination, color fundus photography, spectral-domain optical coherence tomography, infrared reflectance, autofluorescence, optical coherence tomography angiography, and adaptive optics scanning laser ophthalmoscopy. RESULTS: A 54-year-old white man with no significant medical history and history of smoking presented with bilateral multiple serous and vitelliform detachments consistent with acute exudative polymorphous vitelliform maculopathy...
May 16, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28514814/-possibilities-and-limitations-of-oct-angiography-in-patients-with-central-serous-chorioretinopathy
#9
B Cakir, M Reich, S J Lang, A Bühler, A Stahl, D Böhringer, H Agostini, C Lange
Purpose Central serous chorioretinopathy (CSC) is a commonly acquired maculopathy characterized by the accumulation of subretinal fluid at the posterior pole. This study aims to analyze optical coherence tomography angiography (OCTA) findings in patients with acute and chronic CSC and to compare them to conventional imaging methods. Methods A series of 43 consecutive eyes of 29 patients diagnosed with CSC and 18 eyes of 9 healthy control subjects were included in this retrospective study. The OCTA images were assessed and compared to conventional fluorescence (FAG) and indocyanine green angiography (ICG)...
May 17, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28506717/torpedo-maculopathy-with-serous-detachment-of-retinal-pigment-epithelium
#10
G Arcos-Villegas, C Valor-Suarez, J Ruiz-Medrano, A Valverde-Megías, I Flores Moreno, J Donate López
No abstract text is available yet for this article.
May 12, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28503273/bilateral-optic-neuritis-with-maculopathy-a-rare-manifestation-of-dengue-fever
#11
Y L Boo, S Y Lim, P W Chin, F K Hoo
Dengue fever is a common mosquito-borne disease, which is endemic in tropical and subtropical countries. Bilateral optic neuropathy is a relatively unusual dengue-related ocular complication. Here, we present a case of bilateral optic neuritis with maculopathy complicating dengue infection.
2017: Malaysian Family Physician
https://www.readbyqxmd.com/read/28494517/exploration-of-peripapillary-vessel-density-in-highly-myopic-eyes-with-peripapillary-intrachoroidal-cavitation-and-its-relationship-with-ocular-parameters-using-optical-coherence-tomography-angiography
#12
Chen Qiuying, He Jiangnan, Hua Yihong, Fan Ying
IMPORTANCE: Identifying changes of peripapillary vessel density in highly myopic eyes with peripapillary intrachoroidal cavitation (PICC) by optical coherence tomography angiography (OCTA). BACKGROUND: To investigate peripapillary vessel density and its relationship with other ocular parameters in highly myopic eyes with PICC. DESIGN: This was a hospital-based, cross-sectional study. PARTICIPANTS: Thirty-five highly myopic eyes with PICC, 46 highly myopic eyes without PICC and 36 normal eyes were included in this study...
May 11, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28492872/urinary-isoprostane-levels-and-age-related-macular-degeneration
#13
Charumathi Sabanayagam, Weng Kit Lye, Andrzej Januszewski, Riswana Banu Binte Mohammed Abdul, Gemmy Chui Ming Cheung, Neelam Kumari, Tien Y Wong, Ching-Yu Cheng, Ecosse Lamoureux
Purpose: Oxidative stress, characterized by an excessive production of reactive oxygen intermediates has been suggested to play a role in the pathogenesis of age-related macular degeneration (AMD). We examined the association of urinary F2-isoprostanes (F2-IsoPs), a marker of lipid peroxidation and the most reliable marker of oxidative damage with AMD. Methods: We included 238 adults with AMD and 390 age- and sex-matched controls without AMD who participated in a population-based cross-sectional study in Singapore (Singapore Chinese Eye Study, 2009-2011)...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28489707/intravitreal-dexamethasone-ozurdex-implant-for-radiation-maculopathy-secondary-to-stereotactic-radiotherapy-for-posterior-uveal-melanoma
#14
Irem Koc, Sibel Kadayifcilar, Hayyam Kiratli, Bora Eldem
PURPOSE: To evaluate the efficacy of 0.7 mg intravitreal dexamethasone implant in the treatment of radiation maculopathy after stereotactic radiotherapy for posterior uveal melanoma. METHODS: Retrospective chart review of seven eyes of seven consecutive patients was performed. Extracted data included age, sex, initial and follow-up visual acuities and central macular thickness values, intraocular pressure, follow-up time, number of implants, and time elapsed from radiotherapy to implantation...
May 9, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28487377/the-uk-diabetic-retinopathy-electronic-medical-record-uk-dr-emr-users-group-report-2-real-world-data-for-the-impact-of-cataract-surgery-on-diabetic-macular-oedema
#15
Alastair K Denniston, Usha Chakravarthy, Haogang Zhu, Aaron Y Lee, David P Crabb, Adnan Tufail, Clare Bailey, Toks Akerele, Sahar Al-Husainy, Christopher Brand, Louise Downey, Alan Fitt, Rehna Khan, Vineeth Kumar, Aires Lobo, Sajjad Mahmood, Kaveri Mandal, Martin Mckibbin, Geeta Menon, Salim Natha, Jong Min Ong, Marie D Tsaloumas, Atul Varma, Elizabeth Wilkinson, Robert L Johnston, Catherine A Egan
AIM: To assess the rate of 'treatment-requiring diabetic macular oedema (DMO)' in eyes for the two  years before and after cataract surgery. METHODS: Multicentre national diabetic retinopathy (DR) database study with anonymised data extraction across 19 centres from an electronic medical record system. INCLUSION CRITERIA: eyes undergoing cataract surgery in patients with diabetes with no history of DMO prior to study start. The minimum dataset included: age, visual acuity (all time-points), injection episodes, timing of cataract surgery and ETDRS grading of retinopathy and maculopathy...
May 9, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28486276/outcomes-for-ab-interno-bleb-revision-with-a-novel-translimbal-sclerostomy-spatula
#16
Davinder S Grover, Ronald L Fellman
PURPOSE: To report outcomes for a novel ab interno bleb revision technique and spatula. PATIENTS AND METHODS: This is a retrospective chart review. RESULTS: A total of 21 eyes of 21 patients underwent ab interno bleb revision with the Grover-Fellman biplanar sclerostomy spatula. Mitomycin C was given at least 1 week preoperation. The mean age of the patients and blebs were 67 and 6.75 years, respectively. The mean follow-up is 10.6 months (range: 3 to 17 mo)...
May 8, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28481040/optical-coherence-tomography-morphology-and-evolution-in-cblc-disease-related-maculopathy-in-a-case-series-of-very-young-patients
#17
Giacomo M Bacci, Maria A Donati, Elisabetta Pasquini, Francis Munier, Catia Cavicchi, Amelia Morrone, Andrea Sodi, Vittoria Murro, Nuria Garcia Segarra, Claudio Defilippi, Leonardo Bussolin, Roberto Caputo
PURPOSE: To describe the retinal structure of a group of patients affected by methylmalonic aciduria with homocystinuria cblC type, caused by mutations in the MMACHC gene, using spectral domain optical coherence tomography (SD-OCT). METHODS: Young patients (n = 11, age 0-74 months) with cblC disease, detected by newborn screening or clinically diagnosed within 40 days of life, underwent molecular analysis and complete ophthalmic examination, including fundus photography and SD-OCT...
May 8, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28470647/torpedo-maculopathy-associated-with-choroidal-neovascularization
#18
D Jurjevic, C Böni, D Barthelmes, K Fasler, M Becker, S Michels, J Stemmle, C Herbort, S A Zweifel
Background Torpedo maculopathy is a very rare, congenital, usually unilateral hypopigmented lesion in the temporal macula. Material and Methods This retrospective case series describes three patients with torpedo maculopathy. Results The first two cases demonstrate typical clinical and imaging findings of torpedo maculopathy in asymptomatic patients. The third case relates to a symptomatic young patient with a torpedo lesion, a smaller satellite lesion, and evidence of choroidal neovascularization confirmed by fluorescence angiography...
April 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28470646/vitrectomy-with-fovea-sparing-internal-limiting-membrane-peeling-for-myopic-foveoschisis
#19
C Seppey, T J Wolfensberger
Background Myopic foveoschisis is a rare form of a tractional maculopathy, which occurs in patients with elevated axial length. The contraction of the posterior hyaloid exerts tangential traction on the retinal surface with a subsequent continuous splitting of the retinal layers. Internal limiting membrane (ILM) peeling has been advocated in foveoschisis, but it has been associated with post-operative macular hole formation. We report on a modified surgical technique, which spares the fovea and may reduce the risk for macular hole formation...
April 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28452378/scharioth-macula-lens-a-new-intraocular-implant-for-low-vision-patients-with-stabilized-maculopathy-first-experience
#20
Jana Nekolova, Pavel Rozsival, Martin Sin, Nada Jiraskova
AIMS: To present the initial results of Scharioth Macula Lens (SML) implantation. The SML is a new add-on intraocular lens designed to increase uncorrected near visual acuity (UCVA) in patients with stabilized maculopathy. METHODS: Eight patients were included in the study. All met the indication criteria before SML implantation. An SML was implanted in the better seeing eye. Near and distance visual acuity were tested. Possible complications and patient complaints were recorded and patients were asked about their quality of vision after SML implantation...
April 26, 2017: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
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