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https://www.readbyqxmd.com/read/28731058/multicenter-study-of-pars-plana-vitrectomy-for-optic-disc-pit-maculopathy-macpit-study
#1
R Avci, Z Kapran, Ş Ozdek, M Y Teke, O Oz, D Guven, S Yilmaz, B Kaderli, A H Durukan, G Sobaci, Y B Unver, L Akduman, S Kaynak, I Dogan, U U Inan
PurposeTo evaluate surgical intervention with pars plana vitrectomy (PPV) for correction of optic disc pit maculopathy (ODP-M).Patients and methodsRetrospective chart review from 13 centres of 51 eyes of 50 patients with ODP-M who underwent PPV between 2002-2014. Anatomic and final best-corrected visual acuity (BCVA) outcomes were evaluated for all cases with different adjuvant techniques.ResultsThere were 23 males and 27 females with median age 25.5 (6-68) years. Preoperative median foveal thickness was 694...
July 21, 2017: Eye
https://www.readbyqxmd.com/read/28724375/bilateral-idiopathic-retinal-vasculitis-following-coxsackievirus-a4-infection-a-case-report
#2
Izumi Mine, Manzo Taguchi, Yutaka Sakurai, Masaru Takeuchi
BACKGROUND: Coxsackieviruses are members of a group of viruses called the enteroviruses, which may cause respiratory and gastrointestinal symptoms, erythema, meningoencephalitis, myocarditis, pericarditis, and myositis. Unilateral acute idiopathic maculopathy caused by coxsackievirus A16 has been associated with hand, foot, and mouth disease, but only a few reports describe retinitis associated with coxsackievirus serotype B3 or B4. We report a case of bilateral multifocal obstructive retinal vasculitis that developed after coxsackievirus A4 infection...
July 19, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28720613/retrospective-analysis-of-newly-recorded-certifications-of-visual-impairment-due-to-diabetic-retinopathy-in-wales-during-2007-2015
#3
Rebecca L Thomas, Stephen D Luzio, Rachel V North, Sanjiv Banerjee, Antra Zekite, Catey Bunce, David R Owens
OBJECTIVE: The aim of this study was to analyse the changes in new certifications for both sight impairment (SI) and severe sight impairment (SSI, blindness) in Wales due to diabetic retinopathy (DR)/maculopathy between 2007 and 2015. RESEARCH DESIGN AND METHODS: This is a retrospective analysis of annual data of new certifications for visual impairment and blindness (Certificate of Vision Impairment) for England and Wales derived from the national database provided by the Certifications Office, Moorfields Eye Hospital, over a period of 8 years from 2007...
July 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28717807/vitamin-d-status-and-prevalent-early-age-related-macular-degeneration-in-african-americans-and-caucasians-the-atherosclerosis-risk-in-communities-aric-study
#4
A E Millen, J Nie, M W Sahli, J A Mares, K J Meyers, B E K Klein, M J LaMonte, P L Lutsey, C A Andrews, R Klein
OBJECTIVES: Vitamin D status has been hypothesized to protect against development of early age-related macular degeneration (AMD) via its anti-inflammatory properties and its possible beneficial influence on blood pressure control. We investigated the association between vitamin D status and prevalent early AMD in a community-based cohort. DESIGN: This was a cross-sectional study. SETTING: This was a secondary data analysis of already existing data from the Atherosclerosis Risk in Communities Study (ARIC) cohort collected from 1990 to 1995...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28710187/utility-of-microscope-integrated-optical-coherence-tomography-mioct-in-the-treatment-of-myopic-macular-hole-retinal-detachment
#5
Atul Kumar, Prateek Kakkar, Raghav Dinesh Ravani, Ashish Markan
Macular hole-associated retinal detachment in high myopia is described as a final stage in progression of myopic traction maculopathy (MTM).(1â€"3) Shimada et al(4) described the progressive stages of MTM from macular retinoschisis to serous retinal detachment in high myopia. Stage 4 MTM is characterised as disappearance of retinoschisis with progression to retinal detachment due to macular hole formation. It is hypothesised that vitreoschisis and abnormal vitreo-retinal interface create the premacular tangential traction...
July 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28703135/genome-wide-association-study-of-neovascular-age-related-macular-degeneration-in-the-thai-population
#6
Paisan Ruamviboonsuk, Mongkol Tadarati, Panisa Singhanetr, Sukanya Wattanapokayakit, Punna Kunhapan, Thanyapat Wanitchanon, Nuanjun Wichukchinda, Taisei Mushiroda, Masato Akiyama, Yukihide Momozawa, Michiaki Kubo, Surakameth Mahasirimongkol
We performed a genome-wide association study on 377 cases of neovascular age-related macular degeneration (AMD) and 1074 controls to determine the association of previously reported genetic variants associated with neovascular AMD in the Thai population. All patients were of Thai ancestry. We confirmed the association of age-related maculopathy susceptibility 2 (ARMS2) rs10490924 (P=7.38 × 10(-17)), HTRA1 rs11200638 (P=5.47 × 10(-17)) and complement factor H gene (CFH) rs800292 (P=2.53 × 10(-8)) with neovascular AMD, all loci passing the genome-wide significance level (P<5...
July 13, 2017: Journal of Human Genetics
https://www.readbyqxmd.com/read/28701715/clinical-relevance-of-reduced-decorrelation-signals-in-the-diabetic-inner-choroid-on-optical-coherence-tomography-angiography
#7
Yoko Dodo, Kiyoshi Suzuma, Kenji Ishihara, Shin Yoshitake, Masahiro Fujimoto, Tatsuya Yoshitake, Yuko Miwa, Tomoaki Murakami
Diabetes induces lesions of the retinal and choroidal capillaries, which promote the pathogenesis of diabetic retinopathy (DR). The decorrelation signals in optical coherence tomography angiography (OCTA) represent the blood flow and vascular structure, and three-dimensional OCTA images enable individual capillary layers to be evaluated separately. The current study documented that en-face OCTA images revealed spots of flow void in the choriocapillaris layer in eyes with DR. Quantitative investigation demonstrated that non-flow areas within the central subfield (CSF) increased in eyes with more severe DR grades...
July 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28701214/the-effect-of-oral-acetazolamide-on-cystoid-macular-edema-in-hydroxychloroquine-retinopathy-a-case-report
#8
Eun Hee Hong, Seong Joon Ahn, Han Woong Lim, Byung Ro Lee
BACKGROUND: Hydroxychloroquine (HCQ) retinopathy can accompany other retinal complications such as cystoid macular edema (CME), which leads to central visual loss. We report a case of CME with HCQ retinopathy that improved with the use of oral acetazolamide, and discussed the possible mechanisms of CME in HCQ retinopathy using multimodal imaging modalities. CASE PRESENTATION: A 62-year-old patient with systemic lupus erythematosus (SLE) and HCQ retinopathy developed bilateral CME with visual decline...
July 12, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28692596/inadvertent-cyclodialysis-cleft-and-hypotony-following-ab-interno-trabeculotomy-using-the-trabectome-device-requiring-surgical-repair
#9
Thomas A Berk, Jella A An, Iqbal Ike K Ahmed
PURPOSE: To report the first case of inadvertent cyclodialysis cleft and hypotony requiring surgical repair following ab-interno trabeculotomy (AIT) using the Trabectome device, and the postoperative clinical results following direct suture cyclopexy. METHODS: A 55-year-old man with hypotonous maculopathy secondary to cyclodialysis cleft inadvertently created 3 years earlier during AIT using the Trabectome device was referred for repair. Direct suture cyclopexy was performed and topical homatropine and dexamethasone drops were prescribed postoperatively...
July 7, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28686709/axial-length-changes-in-highly-myopic-eyes-and-influence-of-myopic-macular-complications-in-japanese-adults
#10
Hideharu Ohsugi, Yasushi Ikuno, Tomohiro Shoujou, Kanako Oshima, Eiko Ohsugi, Hitoshi Tabuchi
PURPOSE: To investigate changes of the axial length in normal eyes and highly myopic eyes and influence of myopic macular complications in Japanese adults. STUDY DESIGN: Retrospective longitudinal case series. METHODS: The changes in the axial length of 316 eyes from 316 patients (mean age, 63.8 ± 9.0 years; range, 34-82; 240 females) examined using IOLMaster with a follow-up period of at least 1 year were studied. This study included 85 non-highly myopic eyes (|refractive error| ≤ 5 diopters; 63 females; non-highly myopic group), 165 highly myopic eyes (refractive error ≤ -6 diopters or axial length ≥ 26 mm; 124 females) without macular complications (no complications group), 32 eyes (25 females) with myopic traction maculopathy (MTM group), and 34 eyes (28 females) with myopic choroidal neovascularization (CNV group)...
2017: PloS One
https://www.readbyqxmd.com/read/28684650/are-we-making-good-use-of-our-public-resources-the-false-positive-rate-of-screening-by-fundus-photography-for-diabetic-macular-oedema
#11
R Lm Wong, C W Tsang, D Sh Wong, S McGhee, C H Lam, J Lian, J Wy Lee, J Sm Lai, V Chong, I Yh Wong
INTRODUCTION: A large proportion of patients diagnosed with diabetic maculopathy using fundus photography and hence referred to specialist clinics following the current screening guidelines adopted in Hong Kong and United Kingdom are found to be false-positive, implying that they did not have macular oedema. This study aimed to evaluate the false-positive rate of diabetic maculopathy screening using the objective optical coherence tomography scan. METHODS: This was a cross-sectional observational study...
July 7, 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/28683455/binocular-fixation-reduces-fixational-eye-movements-in-the-worst-eye-of-patients-with-center-involving-diabetic-macular-edema
#12
Nanna Stæhr Jakobsen, Dorte Ancher Larsen, Toke Bek
PURPOSE: Treatment of diabetic maculopathy with vascular endothelial growth factor inhibitors is in some patients ineffective, and, therefore, parameters predicting visual outcome after treatment should be identified. It has been shown that fixational saccades are increased in patients with reduced visual acuity secondary to diabetic maculopathy, but it is unknown to what extent these saccades in an eye affected by diabetic maculopathy are influenced by the other eye during binocular fixation...
July 7, 2017: Ophthalmic Research
https://www.readbyqxmd.com/read/28681138/ocriplasmin-treatment-for-vitreomacular-traction-in-real-life-can-the-indication-spectrum-be-expanded
#13
Kleanthis Manousaridis, Silvia Peter-Reichart, Stefan Mennel
PURPOSE: To evaluate the efficacy of intravitreal ocriplasmin for the resolution of vitreomacular traction (VMT) with or without a full thickness macular hole (FTMH) in the clinical setting and to assess whether the indication spectrum of this treatment modality can be expanded beyond that of the MIVI-TRUST trials. METHODS: The records of patients with VMT with or without FTMH, who were treated with intravitreal ocriplasmin were reviewed. Patients were divided in two groups...
July 5, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28677229/evaluating-the-impact-of-optical-coherence-tomography-in-diabetic-retinopathy-screening-for-an-aboriginal-population
#14
Richard A O'Halloran, Angus W Turner
IMPORTANCE: Optical Coherence Tomography (OCT) is used routinely in management of diabetic eye disease but has not been evaluated in Australian outreach settings for screening programs. BACKGROUND: To evaluate the use of OCT combined with a fundus camera compared to a fundus camera only in a telehealth diabetic retinopathy (DR) screening program for Aboriginal Australians. DESIGN: Retrospective comparative study. PARTICIPANTS: Patients with diabetes at two Aboriginal Health Services...
July 4, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28676991/outcomes-of-microscope-integrated-intraoperative-optical-coherence-tomography-guided-center-sparing-internal-limiting-membrane-peeling-for-myopic-traction-maculopathy-a-novel-technique
#15
Atul Kumar, Raghav Ravani, Aditi Mehta, Sriram Simakurthy, Chirakshi Dhull
PURPOSE: To evaluate the outcomes of pars plana vitrectomy (PPV) with microscope-integrated intraoperative optical coherence tomography (I-OCT)-guided traction removal and center-sparing internal limiting membrane (cs-ILM) peeling. METHODS: Nine eyes with myopic traction maculopathy as diagnosed on SD-OCT underwent PPV with I-OCT-guided cs-ILM peeling and were evaluated prospectively for resolution of central macular thickness (CMT) and improvement in best-corrected visual acuity (BCVA), and complications, if any, were noted...
July 4, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28665476/incidence-and-evolution-of-subretinal-precipitates-in-optic-disc-pit-maculopathy
#16
Irini Chatziralli, George Theodossiadis, Dimitrios Brouzas, Panagiotis Theodossiadis
PURPOSE: To study the evolution of subretinal precipitates coexistent with optic disc pit (ODP) maculopathy from their appearance at baseline examination until their absorption after successful treatment. METHODS: Participants in this retrospective, multicenter study were 42 patients with ODP maculopathy, in whom complete ocular examination was performed, including visual acuity (VA) measurement, slit-lamp examination, color or red-free fundus photography, and optical coherence tomography at baseline after surgical treatment...
June 26, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28655539/myopic-choroidal-neovascularization-review-guidance-and-consensus-statement-on-management
#17
Chui Ming Gemmy Cheung, Jennifer J Arnold, Frank G Holz, Kyu Hyung Park, Timothy Y Y Lai, Michael Larsen, Paul Mitchell, Kyoko Ohno-Matsui, Shih-Jen Chen, Sebastian Wolf, Tien Yin Wong
TOPIC: The aim of this article is to review and compile available information on the classification, pathophysiology, and clinical features of myopic choroidal neovascularization (CNV); to describe the latest data on the management of this disease; and to present guidance. CLINICAL RELEVANCE: In the United States, myopia affects approximately 34 million people (2010), and similar figures have been reported in Europe. Pathologic myopia (PM), a possible consequence of myopia, is estimated to affect up to 3% of the global population...
June 24, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28648381/clinical-phenotypes-of-poppers-maculopathy-and-their-links-to-visual-and-anatomic-recovery
#18
Laure B Van Bol, Rengin A Kurt, Pearse A Keane, Bishwanath Pal, Sobha Sivaprasad
No abstract text is available yet for this article.
June 22, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28647462/optical-coherence-tomography-angiography-of-macular-features-after-proton-beam-radiotherapy-for-small-choroidal-melanoma
#19
Alexandre Sellam, Florence Coscas, Livia Lumbroso-Le Rouic, Rémi Dendale, Marco Lupidi, Gabriel Coscas, Laurence Desjardins, Nathalie Cassoux
PURPOSE: To describe the macular features of patients treated with proton beam therapy for choroidal melanoma (CM), using the optical coherence tomography-angiography (OCTA). DESIGN: Retrospective case-control study. METHODS: This study included patients treated with proton beam radiotherapy (PBR) for a small CM. Only patients that had received 100% of the dose 60 GyEBR to the macular area were included in the analysis. All the patients have undergone a full ophthalmological examination including: visual acuity, OCT B-scan and OCTA...
June 21, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28644209/an-atypical-case-of-paracentral-acute-middle-maculopathy
#20
Cheryl Haskes, Shannon Santapaola, Jordan Zinn
PURPOSE: This is a case presentation of paracentral acute middle maculopathy in a 33-year-old white man with borderline hyperlipidemia. Paracentral acute middle maculopathy was originally thought to be a variant of acute macular neuroretinopathy; however, it is now generally accepted that these two conditions are separate disease entities. The etiology, evolution, and pathophysiology of acute macular neuroretinopathy and paracentral acute middle maculopathy are discussed, as well as current diagnostic techniques...
June 21, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
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