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https://www.readbyqxmd.com/read/27927843/risk-of-childhood-mortality-in-family-members-of-men-with-poor-semen-quality
#1
Heidi A Hanson, Erik N Mayer, Ross E Anderson, Kenneth I Aston, Douglas T Carrell, Justin Berger, William T Lowrance, Ken R Smith, James M Hotaling
STUDY QUESTION: What is the familial childhood mortality in first-degree (FDR) and second-degree relatives (SDR) of patients undergoing semen analysis (SA)? SUMMARY ANSWER: The relationship between infertility and congenital malformations (CM) in offspring is complex, with an increased risk of death due to CM in FDR, but not SDR, of men with lower semen parameters. WHAT IS KNOWN ALREADY: Semen quality is an established predictor of men's somatic health...
December 6, 2016: Human Reproduction
https://www.readbyqxmd.com/read/27925387/microcomputed-tomography-evaluation-of-volumetric-shrinkage-of-bulk-fill-composites-in-class-ii-cavities
#2
Hamad Algamaiah, Camila S Sampaio, Lindiane C Rigo, Malvin N Janal, Marcelo Giannini, Estevam A Bonfante, Paulo G Coelho, Andre F Reis, Ronaldo Hirata
PURPOSE: This study aimed to quantify polymerization shrinkage of one conventional and three bulk-fill composites, under bonded and unbonded conditions, in Class II preparations using 3D microcomputed tomography (μCT) and report its location. MATERIALS AND METHODS: Preparations (2.5 mm occlusal depth × 4 mm wide × 4 mm mesial box and 1 mm beyond the CEJ distal box depth) were made in 48 human extracted molars (n = 6). Four composites were tested, one regular (Vitalescence/VIT) and three bulk-fill: SureFil SDR Flow (SDR), Tetric EvoCeram Bulk Fill (TET), and Filtek flowable Bulk Fill (FIL)...
December 7, 2016: Journal of Esthetic and Restorative Dentistry
https://www.readbyqxmd.com/read/27908676/effect-of-selective-dorsal-rhizotomy-on-daily-care-and-comfort-in-non-walking-children-and-adolescents-with-severe-spasticity
#3
A I Buizer, P E M van Schie, E A M Bolster, W J van Ouwerkerk, R L Strijers, L A van de Pol, A Stadhouder, J G Becher, R J Vermeulen
BACKGROUND: In non-walking children with severe spasticity, daily care can be difficult and many patients suffer from pain. Selective dorsal rhizotomy (SDR) reduces spasticity in the legs, and therefore has the potential to improve daily care and comfort. AIM: To examine effects of SDR on daily care and comfort in non-walking children with severe spasticity due to different underlying neurological conditions. METHODS: Medical history, changes in daily care and comfort and satisfaction with outcome were assessed retrospectively in non-walking children who underwent SDR in our center, with a mean follow-up of 1y 7m (range 11m-4y 3m)...
October 22, 2016: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/27892836/comparison-of-internal-adaptation-in-class-ii-bulk-fill-composite-restorations-using-micro-ct
#4
S H Han, S H Park
PURPOSE: This study compared the internal adaptation of bulk-fill composite restorations in class II cavities and explored the relationship between internal adaptation and polymerization shrinkage or stress. METHODS AND MATERIALS: Standardized mesio-occluso-distal cavities were prepared in 40 extracted human third molars and randomly divided into five groups (n=8). After having been applied by total-etch XP bond (Dentsply Caulk, Milford, DE, USA) and light curing, the teeth were restored with the following resin composites: group 1, Filtek Z350 (3M ESPE, St...
November 28, 2016: Operative Dentistry
https://www.readbyqxmd.com/read/27885743/influence-of-polymerisation-method-and-type-of-fibre-on-fracture-strength-of-endodontically-treated-teeth
#5
Neslihan Tekçe, Kansad Pala, Safa Tuncer, Mustafa Demirci, Merve Efe Serim
The aim of this study was to investigate (i) the effect of direct or indirect polymerisation of adhesive-impregnated ribbon fibre under 4-mm bulk-filled composites on fracture strength; (ii) to compare polyethylene ribbon fibre-reinforcement composites with short fibre-reinforced composite; and (iii) the effectiveness of polyethylene ribbon fibre according to the restorative materials used (low-viscous bulk-fill composite, high-viscous flowable composite or conventional paste composite). Seventy molars were divided into seven groups; (groups 1-2) Ribbond-reinforced Surefil-SDR; (group 3) Ribbond-reinforced G Aenial Flo; (group 4) Ribbond-reinforced G Aenial Posterior; (group 5) short fibre-reinforced composite everX Posterior; (group 6) unfilled cavity; (group 7) intact teeth...
November 25, 2016: Australian Endodontic Journal: the Journal of the Australian Society of Endodontology Inc
https://www.readbyqxmd.com/read/27856484/leprosy-post-exposure-prophylaxis-lpep-programme-study-protocol-for-evaluating-the-feasibility-and-impact-on-case-detection-rates-of-contact-tracing-and-single-dose-rifampicin
#6
Tanja Barth-Jaeggi, Peter Steinmann, Liesbeth Mieras, Wim van Brakel, Jan Hendrik Richardus, Anuj Tiwari, Martin Bratschi, Arielle Cavaliero, Bart Vander Plaetse, Fareed Mirza, Ann Aerts
INTRODUCTION: The reported number of new leprosy patients has barely changed in recent years. Thus, additional approaches or modifications to the current standard of passive case detection are needed to interrupt leprosy transmission. Large-scale clinical trials with single dose rifampicin (SDR) given as post-exposure prophylaxis (PEP) to contacts of newly diagnosed patients with leprosy have shown a 50-60% reduction of the risk of developing leprosy over the following 2 years. To accelerate the uptake of this evidence and introduction of PEP into national leprosy programmes, data on the effectiveness, impact and feasibility of contact tracing and PEP for leprosy are required...
November 17, 2016: BMJ Open
https://www.readbyqxmd.com/read/27856036/antipyrine-removal-by-tio2-photocatalysis-based-on-spinning-disc-reactor-technology
#7
A J Expósito, D A Patterson, W S W Mansor, J M Monteagudo, E Emanuelsson, I Sanmartín, A Durán
The photo-degradation of the emerging contaminant antipyrine (AP) was studied and optimized in a novel photocatalytic spinning disc reactor (SDR). A heterogeneous process (UV/H2O2/TiO2) was used. TiO2 was immobilized on the surface of a glass disc using a sol-gel method. A factorial design of experiments followed by a Neural Networks fitting allowed the optimal conditions to be determined for treating 50 mg/L of AP. Under these conditions (pH = 4; [H2O2]0 = 1500 mg/L; disc speed = 500 rpm; flowrate = 25 mL/s), AP was completely degraded in 120 min and regeneration of the disc allowed 10 cycles with no loss in efficiency...
November 14, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/27844211/morbid-obesity-and-outcome-of-ectopic-pregnancy-following-capped-single-dose-regimen-methotrexate
#8
Luis R Hoyos, Mokerrum Malik, Marvin Najjar, Javier Rodriguez-Kovacs, Mazen Abdallah, Gustavo Vilchez, Awoniyi O Awonuga
PURPOSE: Evaluate whether morbid obesity influenced resolution, number of doses or ultimately surgical management of tubal ectopic pregnancy (TEP) when treated with single-dose regimen methotrexate (SDR-MTX) capped at 100 mg. METHODS: Retrospective cohort study of patients with a diagnosis of TEP who underwent MTX treatment from 2000 to 2013. Patients were excluded if initial β-hCG <1000 mIU/mL, did not have β-hCG follow-up or were not treated with SDR-MTX...
November 14, 2016: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/27844108/transcriptional-responses-of-the-bacterium-burkholderia-terrae-bs001-to-the-fungal-host-lyophyllum-sp-strain-karsten-under-soil-mimicking-conditions
#9
Irshad Ul Haq, Francisco Dini-Andreote, Jan Dirk van Elsas
In this study, the mycosphere isolate Burkholderia terrae BS001 was confronted with the soil fungus Lyophyllum sp. strain Karsten on soil extract agar plates in order to examine its transcriptional responses over time. At the initial stages of the experiment (T1-day 3; T2-day 5), contact between both partner organisms was absent, whereas in the final stage (T3-day 8), the two populations made intimate physical contact. Overall, a strong modulation of the strain BS001 gene expression patterns was found. First, the stationary-phase sigma factor RpoS, and numerous genes under its control, were strongly expressed as a response to the soil extract agar, and this extended over the whole temporal regime...
November 14, 2016: Microbial Ecology
https://www.readbyqxmd.com/read/27836116/effect-of-layer-thickness-on-the-elution-of-bulk-fill-composite-components
#10
Lena Rothmund, Franz-Xaver Reichl, Reinhard Hickel, Panorea Styllou, Marianthi Styllou, Kai Kehe, Yang Yang, Christof Högg
OBJECTIVE: An increment layering technique in a thickness of 2mm or less has been the standard to sufficiently convert (co)monomers. Bulk fill resin composites were developed to accelerate the restoration process by enabling up to 4mm thick increments to be cured in a single step. The aim of the present study is to investigate the effect of layer thickness on the elution of components from bulk fill composites. METHODS: The composites ELS Bulk fill, SDR Bulk fill and Venus Bulkfill were polymerized according to the instruction of the manufacturers...
November 8, 2016: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/27825888/sdr-elisa-ultrasensitive-and-high-throughput-nucleic-acid-detection-based-on-antibody-like-dna-nanostructure
#11
Junlin Wen, Junhua Chen, Li Zhuang, Shungui Zhou
An ultrasensitive and high-throughput nucleic acid detection system, termed as strand displacement reaction-enzyme linked immunosorbent assay (SDR-ELISA), has been developed on the basis of antibody-like DNA nanostructures. Three digoxigenin or biotin modified hairpin probes are utilized to construct antibody-like DNA nanostructures that feature affinity toward streptavidin and anti-digoxigenin antibody via isothermal target-triggered SDR amplification. These antibody-like nanostructures have been employed to conjugate horseradish-peroxidase-labeled anti-digoxigenin antibody with streptavidin that is immobilized on microliter plate wells for enzyme-linked colorimetric assay...
November 2, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27820696/influence-of-the-compliance-and-layering-method-on-the-wall-deflection-of-simulated-cavities-in-bulk-fill-composite-restoration
#12
Y-J Kim, R Kim, J L Ferracane, I-B Lee
The aim of this study was to investigate the effects of the layering method and compliance on the wall deflection of simulated cavities in bulk-fill and conventional composite restorations and to examine the relationships between the wall deflection and the polymerization shrinkage, flexural modulus, and polymerization shrinkage stress of composites. Six light-cured composites were used in this study. Two of these were conventional methacrylate-based composites (Filtek Z250 and Filtek Z350 XT Flowable [Z350F]), whereas four were bulk-fill composites (SonicFill, Tetric N-Ceram Bulk-Fill, SureFil SDR Flow [SDR], and Filtek Bulk-Fill)...
November 2016: Operative Dentistry
https://www.readbyqxmd.com/read/27809489/structural-insights-into-the-drosophila-melanogaster-retinol-dehydrogenase-a-member-of-the-short-chain-dehydrogenase-reductase-family
#13
Lukas Hofmann, Yaroslav Tsybovsky, Nathan S Alexander, Darwin Babino, Nicole Yishi Leung, Craig Montell, Surajit Banerjee, Johannes von Lintig, Krzysztof Palczewski
The 11-cis-retinylidene chromophore of visual pigments isomerizes upon interaction with a photon, initiating a downstream cascade of signaling events that ultimately lead to visual perception. 11-cis-Retinylidene is regenerated through the enzymatic transformations collectively called visual cycle. The first and rate-limiting enzymatic reaction within this cycle, i.e. the reduction of all-trans-retinal to all-trans-retinol, is catalyzed by retinol dehydrogenases. Here, we solved the structure of Drosophila melanogaster photoreceptor retinol dehydrogenase (PDH) isoform C (PDHc) that belongs to the short-chain dehydrogenase/reductase (SDR) family...
November 3, 2016: Biochemistry
https://www.readbyqxmd.com/read/27793605/characterization-of-human-short-chain-dehydrogenase-reductase-sdr16c-family-members-related-to-retinol-dehydrogenase-10
#14
Mark K Adams, Seung-Ah Lee, Olga V Belyaeva, Lizhi Wu, Natalia Y Kedishvili
All-trans-retinoic acid (RA) is a bioactive derivative of vitamin A that serves as an activating ligand for nuclear transcription factors, retinoic acid receptors. RA biosynthesis is initiated by the enzymes that oxidize retinol to retinaldehyde. It is well established that retinol dehydrogenase 10 (RDH10, SDR16C4), which belongs to the 16C family of the short chain dehydrogenase/reductase (SDR) superfamily of proteins, is the major enzyme responsible for the oxidation of retinol to retinaldehyde for RA biosynthesis during embryogenesis...
October 25, 2016: Chemico-biological Interactions
https://www.readbyqxmd.com/read/27792696/-smoking-parental-as-risk-factor-for-the-development-of-neonatal-respiratory-distress-syndrome
#15
Mario Alberto Arrieta-Mendoza, Arnoldo Salas-Delgado
: The Respiratory Distress Syndrome (RDS) is one of the most frequent pathologies in the premature neonates and a major cause of morbidity and mortality. The objective of this study was to determine the association between parental smoking and the development of this syndrome. This study was an observational, longitudinal, retrospective, analytical, prolective type, with the neonates in the Neonatal Intensive Care Unit (NICU) of the Hospital Regional Monterrey (HRMI), who developed RDS (cases) and those that do not (controls), during the period January 2012 - April 2015, in both groups were determined the smoking habits of the father and the statistical analysis using SPSS (v...
September 2016: Gaceta Médica de México
https://www.readbyqxmd.com/read/27757432/single-level-selective-dorsal-rhizotomy-for-spastic-cerebral-palsy
#16
David Graham, Kristian Aquilina, Stephanie Cawker, Simon Paget, Neil Wimalasundera
The management of cerebral palsy (CP) is complex and requires a multidisciplinary approach. Selective dorsal rhizotomy (SDR) is a neurosurgical technique that aims to reduce spasticity in the lower limbs. A minimally invasive approach to SDR involves a single level laminectomy at the conus and utilises intraoperative electromyography (EMG). When combined with physiotherapy, SDR is effective in selected children and has minimal complications. This review discusses the epidemiology of CP and the management using SDR within an integrated multidisciplinary centre...
September 2016: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/27749696/hyperspectral-autofluorescence-imaging-of-drusen-and-retinal-pigment-epithelium-in-donor-eyes-with-age-related-macular-degeneration
#17
Yuehong Tong, Tal Ben Ami, Sungmin Hong, Rainer Heintzmann, Guido Gerig, Zsolt Ablonczy, Christine A Curcio, Thomas Ach, R Theodore Smith
PURPOSE: To elucidate the molecular pathogenesis of age-related macular degeneration (AMD) and interpretation of fundus autofluorescence imaging, the authors identified spectral autofluorescence characteristics of drusen and retinal pigment epithelium (RPE) in donor eyes with AMD. METHODS: Macular RPE/Bruch membrane flat mounts were prepared from 5 donor eyes with AMD. In 12 locations (1-3 per eye), hyperspectral autofluorescence images in 10-nm-wavelength steps were acquired at 2 excitation wavelengths (λex 436, 480 nm)...
September 30, 2016: Retina
https://www.readbyqxmd.com/read/27747835/mortality-rates-in-users-of-typical-and-atypical-antipsychotics-a-database-study-in-poland
#18
Pawel Zagozdzon, Bartosz Goyke, Magdalena Wrotkowska
BACKGROUND: The role of antipsychotics in influencing mortality of patients with mental disorders is still unexplained. OBJECTIVE: The aim of this study was to determine mortality rates of patients treated with atypical and typical antipsychotics and to compare these data with the mortality rates for the general population. METHODS: The study was based on the 2008-2012 prescription drug reimbursement data from the Polish National Health Fund in Gdansk and mortality data from the death registry...
September 2016: Drugs—Real World Outcomes
https://www.readbyqxmd.com/read/27725515/shear-bond-strength-of-different-dentin-substitute-restorative-materials-to-dentin-of-primary-teeth
#19
Faika Abdelmegid, Fouad Salama, Nawaf Albogami, Muhannad Albabtain, Abdulkareem Alqahtani
This in vitro investigation compared the shear bond strength (SBS) of four dentin substitute/replacement materials to caries-affected dentin of primary teeth. Dentin surfaces were randomly divided into four groups of 12 each according to the material used as follows: SDR/Smart Dentin Replacement, Biodentine, Multicore Flow, and Fuji II LC. The SBS was measured and failure modes were determined. There was a statistically significant difference in the mean values of SBS among the four materials (F=741.523, p<0...
2016: Dental Materials Journal
https://www.readbyqxmd.com/read/27722199/radiopacity-of-methacrylate-and-silorane-composite-resins-using-a-digital-radiographic-system
#20
Leily Macedo Firoozmand, Mariana Gonçalves Cordeiro, Marcos André Dos Santos Da Silva, Rudys Rodolfo De Jesus Tavarez, Etevaldo Matos Maia Filho
The aim of this study was to evaluate the radiopacity of silorane and methacrylate resin composites, comparing them to the enamel, dentin, and aluminum penetrometer using a digital image. From six resin composites (Filtek™ P90, Filtek Z350, Filtek Z350 XT flow, Tetric Ceram, TPH Spectrum, and SureFil SDR flow) cylindrical disks (5 × 1 mm) were made and radiographed by a digital method, together with a 15-step aluminum step-wedge and a 1 mm slice of human tooth. The degree of radiopacity of each image was quantified using digital image processing...
2016: TheScientificWorldJournal
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