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https://www.readbyqxmd.com/read/29436570/the-effects-of-irradiance-and-exposure-time-on-the-surface-roughness-of-bulk-fill-composite-resin-restorative-materials
#1
Fahad I Alkhudhairy
To evaluate the surface roughness of 4 different bulk-fill resin-based composites cured using different irradiance levels. Methods: This in vitro study was performed in February 2017 to August 2017 at the College of Dentistry, King Saud University. Twenty-four specimens were prepared from each of the bulk-fill materials [Tetric N-Ceram (TNC), SonicFill (SF), Smart Dentin Replacement (SDR), and Filtek Bulk-Fill (FB)] using a brass metal mold, resulting in a total of 96 specimens, cured using a Bluephase N light curing unit...
February 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29424954/discovery-of-a-short-chain-dehydrogenase-from-catharanthus-roseus-that-produces-a-novel-monoterpene-indole-alkaloid
#2
Anna Stavrinides, Evangelos Tatsis, Thu-Thuy Dang, Lorenzo Caputi, Clare Stevenson, David Lawson, Bernd Schneider, Sarah O'Connor
Monoterpene indole alkaloids, a large class of plant natural products, derive from the biosynthetic intermediate strictosidine aglycone. Strictosidine aglycone, which can exist as a variety of isomers, can be reduced to form numerous different structures. We have discovered a short chain alcohol dehydrogenase (SDR) from monoterpene indole alkaloid producing plants (Catharanthus roseus and Rauvolfia serpentina) that reduce strictosidine aglycone and produce an alkaloid that does not correspond to any previously reported compound...
February 9, 2018: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/29412426/selective-dorsal-rhizotomy-in-cerebral-palsy-selection-criteria-and-postoperative-physical-therapy-protocols
#3
Renata D'Agostini Nicolini-Panisson, Ana Paula Tedesco, Maira Rech Folle, Márcio Vinicius Fagundes Donadio
OBJECTIVE: To identify selection criteria for selective dorsal rhizotomy (SDR) in cerebral palsy, to analyze the instruments used for evaluation, and to describe the characteristics of physical therapy in postoperative protocols. DATA SOURCES: Integrative review performed in the following databases: SciELO, PEDro, Cochrane Library, and PubMed. The terms in both Portuguese and English for "cerebral palsy", "selective dorsal rhizotomy", and "physical therapy" were used in the search...
January 15, 2018: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/29410657/multiple-food-animal-borne-route-in-transmission-of-antibiotic-resistant-salmonella-newport-to-humans
#4
Hang Pan, Narayan Paudyal, Xiaoliang Li, Weihuan Fang, Min Yue
Characterization of transmission routes of Salmonella among various food-animal reservoirs and their antibiogram is crucial for appropriate intervention and medical treatment. Here, we analyzed 3728 Salmonella enterica serovar Newport (S. Newport) isolates collected from various food-animals, retail meats and humans in the United States between 1996 and 2015, based on their minimum inhibitory concentration (MIC) toward 27 antibiotics. Random Forest and Hierarchical Clustering statistic was used to group the isolates according to their MICs...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29394140/effect-of-sonic-resin-composite-delivery-on-void-formation-assessed-by-micro-computed-tomography
#5
R Hirata, R R Pacheco, E Caceres, M N Janal, M F Romero, M Giannini, P G Coelho, F A Rueggeberg
OBJECTIVES: The aim of this study was to quantify the internal void volume formation in commercially available, resin composites inserted using conventional or sonic insertion methods, and analyzed using three-dimensional (3D) micro-computed tomography (μCT). METHODS AND MATERIALS: Four resin composites were evaluated: one conventional (Herculite, Ultra, Kerr Corporation, Orange, CA, USA), one flowable bulk fill (SureFil SDR Flow, Dentsply International, York, PA, USA), and two packable bulk fill (SonicFill, Kerr Corporation, and Tetric EvoCeram Bulk Fill, Ivoclar Vivadent Inc, Schaan, Liechtenstein)...
February 2, 2018: Operative Dentistry
https://www.readbyqxmd.com/read/29358529/diametral-tensile-strength-flexural-strength-and-surface-microhardness-of-bioactive-bulk-fill-restorative
#6
Ali Alrahlah
AIM: The aim was to perform comparative analysis of bioactive, contemporary bulk-fill resin-based composites (RBCs) and conventional glass-ionomer materials for flexural strength (FS), diametral tensile strength (DTS), and Vickers hardness number (VHN) in the presence of thermocycling. MATERIALS AND METHODS: Five restorative materials [Tetric N-Ceram Bulk Fill; smart dentin replacement (SDR) Flowable Material; Bioactive restorative material (ACTIVA Bulk Fill); Ketac Universal Aplicap; and GC Fuji II] were evaluated for DTS, FS, and VHN...
January 1, 2018: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29352301/crystal-structure-of-a-udp-glcnac-epimerase-for-surface-polysaccharide-biosynthesis-in-acinetobacter-baumannii
#7
Bhumika S Shah, Heather E Ashwood, Stephen J Harrop, Daniel N Farrugia, Ian T Paulsen, Bridget C Mabbutt
With new strains of Acinetobacter baumannii undergoing genomic analysis, it has been possible to define regions of genomic plasticity (RGPs), encoding specific adaptive elements. For a selected RGP from a community-derived isolate of A. baumannii, we outline sequences compatible with biosynthetic machinery of surface polysaccharides, specifically enzymes utilized in the dehydration and conversion of UDP-N-acetyl-D-glucosamine (UDP-D-GlcNAc). We have determined the crystal structure of one of these, the epimerase Ab-WbjB...
2018: PloS One
https://www.readbyqxmd.com/read/29342126/tailoring-cu-nanoparticle-catalyst-for-methanol-synthesis-using-the-spinning-disk-reactor
#8
Christian Ahoba-Sam, Kamelia V K Boodhoo, Unni Olsbye, Klaus-Joachim Jens
Cu nanoparticles are known to be very active for methanol (MeOH) synthesis at relatively low temperatures, such that smaller particle sizes yield better MeOH productivity. We aimed to control Cu nanoparticle (NP) size and size distribution for catalysing MeOH synthesis, by using the spinning disk reactor. The spinning disk reactor (SDR), which operates based on shear effect and plug flow in thin films, can be used to rapidly micro-mix reactants in order to control nucleation and particle growth for uniform particle size distribution...
January 17, 2018: Materials
https://www.readbyqxmd.com/read/29328167/high-speed-real-time-heterodyne-interferometry-using-software-defined-radio
#9
L M Riobo, F E Veiras, M G Gonzalez, M T Garea, P A Sorichetti
This paper describes the design and performance of a phase demodulation scheme based on software-defined radio (SDR), applied in heterodyne interferometry. The phase retrieval is performed in real time by means of a low-cost SDR with a wideband optoelectronic front-end. Compared to other demodulation schemes, the system is quite simpler, versatile, and of lower cost. The performance of the demodulator is demonstrated by measuring the displacement per volt of a thin-film polymeric piezoelectric transducer based on polyvinylidene fluoride for ultrasonic applications...
January 10, 2018: Applied Optics
https://www.readbyqxmd.com/read/29327136/signal-detection-for-recently-approved-products-adapting-and-evaluating-self-controlled-case-series-method-using-a-us-claims-and-uk-electronic-medical-records-database
#10
Xiaofeng Zhou, Ian J Douglas, Rongjun Shen, Andrew Bate
INTRODUCTION: The Self-Controlled Case Series (SCCS) method has been widely used for hypothesis testing, but there is limited evidence of its performance for safety signal detection. OBJECTIVE: The objective of this study was to evaluate SCCS for signal detection on recently approved products. METHODS: A retrospective study covered the period after three recently marketed drugs were launched through to 31 December 2010 using The Health Improvement Network, a UK primary care database, and Optum, a US claims database...
January 11, 2018: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/29326229/genomic-understanding-of-an-infectious-brain-disease-from-the-desert
#11
Leandro F Moreno, Abdalla A O Ahmed, Balázs Brankovics, Christina A Cuomo, Steph B J Menken, Saad J Taj-Aldeen, Hani Faidah, J Benjamin Stielow, Marcus de M Teixeira, Francesc X Prenafeta-Boldú, Vania A Vicente, Sybren de Hoog
Rhinocladiella mackenziei accounts for the majority of fungal brain infections in the Middle East and is restricted to the arid climate zone between Saudi Arabia and Pakistan. Neurotropic dissemination caused by this fungus has been reported in immunocompromised, but also immunocompetent individuals. If untreated, the infection is fatal. Outside of humans, the environmental niche of R. mackenziei is unknown, and the fungus has been only cultured from brain biopsies. In this paper we describe the whole genome re-sequencing of two Rhinocladiella mackenziei strains from patients in Saudi Arabia and Qatar...
January 11, 2018: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29324064/interchangeability-of-results-from-computerized-and-traditional-administration-of-the-bidr-convenience-can-match-reality
#12
Walter P Vispoel, Carrie A Morris, Sara J Clough
Although interchangeability of results across computer and paper modes of administration is commonly assumed, recent meta-analyses and individual studies continue to reveal mean differences in scores for measures of socially desirable responding (SDR). Results from these studies have also failed to include new methods of scoring and crucial aspects of scaling, reliability, validity, and administration emphasized in professional standards for assessment that are essential in establishing equivalence. We addressed these shortcomings in a comprehensive, repeated measures investigation for 6 ways of scoring the Balanced Inventory of Desirable Responding (BIDR), one of the most frequently administered companion measures of SDR in research and practice...
January 11, 2018: Journal of Personality Assessment
https://www.readbyqxmd.com/read/29310851/enantioselective-synthesis-of-r-phenylephrine-by-serratia-marcescens-bcrc10948-cells-that-homologously-express-sm_sdr
#13
Yi-Chia Kuan, Yue-Bin Xu, Wen-Ching Wang, Ming-Te Yang
A short-chain dehydrogenase/reductase from Serratia marcescens BCRC10948, SM_SDR, has been cloned and expressed in Escherichia coli for the bioconversion of 1-(3-hydroxyphenyl)-2-(methylamino) ethanone (HPMAE) to (R)-phenylephrine[(R)-PE]. However, only 5.11mM (R)-PE was obtained from 10mM HPMAE after a 9h conversion in the previous report. To improve the biocatalytic efficiency, the homologous expression of the SM_SDR in S. marcescens BCRC10948 was achieved using the T5 promoter for expression. By using 2% glycerol as carbon source, we found that 8...
March 2018: Enzyme and Microbial Technology
https://www.readbyqxmd.com/read/29288638/a-single-amino-acid-residue-regulates-the-substrate-affinity-and-specificity-of-indoleamine-2-3-dioxygenase
#14
Hajime J Yuasa, Mayumi Sugiura, Terue Harumoto
Indoleamine 2,3-dioxygenase (IDO) is a heme-containing enzyme that catalyses the oxidative cleavage of L-Trp. The ciliate Blepharisma stoltei has four IDO genes (IDO-I, -II, -III and -IV), which seem to have evolved via two sequential gene duplication events. Each IDO enzyme has a distinct enzymatic property, where IDO-III ha-s a high affinity for L-Trp, whereas the affinity of the other three isoforms for L-Trp is low. IDO-I also exhibits a significant catalytic activity with another indole compound: 5-hydroxy-L-tryptophan (5-HTP)...
December 27, 2017: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/29248578/identification-of-a-fish-short-chain-dehydrogenase-reductase-associated-with-bone-metabolism
#15
Joana Rosa, Cymon J Cox, M Leonor Cancela, Vincent Laizé
Although human and mouse genetics have largely contributed to the better understanding of the mechanisms underlying skeletogenesis, much more remains to be uncovered. In this regard alternative and complementary systems have been sought and cell systems capable of in vitro calcification have been developed to study the mechanisms underlying bone formation. In gilthead seabream (Sparus aurata), a gene coding for an unknown protein that is strongly up-regulated during extracellular matrix (ECM) mineralization of a pre-osteoblast cell line was recently identified as a potentially important player in bone formation...
December 14, 2017: Gene
https://www.readbyqxmd.com/read/29208783/clinical-time-required-and-internal-adaptation-in-cavities-restored-with-bulk-fill-composites
#16
Marcos Gabriel Vianna-de-Pinho, Guilherme Ferreira Rego, Marina Lermenn Vidal, Roberta Caroline Bruschi Alonso, Luis Felipe Jochims Schneider, Larissa Maria Cavalcante
AIM: The aim of this study was to compare the restorative time required and the internal adaptation after thermomechanical aging of class I restorations using either the conventional incremental technique or bulk-fill technique. MATERIALS AND METHODS: Cavities (Class I) were prepared on the occlusal surface of human third molars. 40 teeth were divided into four experimental groups according to the restorative technique (n = 10): G1 = 3 mm increment of Surefill SDR Flow + 1 mm Filtek P60; G2 = 3 mm increment of Filtek Bulk-Fill + 1 mm Filtek P60; G3 = Filtek P60 inserted with incremental technique; G4 = 3 mm increment of Filtek Z350 Flow XT + 1 mm increment of Filtek P60...
December 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29205770/effect-of-tooth-brushing-on-gloss-retention-and-surface-roughness-of-five-bulk-fill-resin-composites
#17
Catherine O'Neill, Laurent Kreplak, Frederick A Rueggeberg, Daniel Labrie, Carlos Alberto Kenji Shimokawa, Richard Bengt Price
OBJECTIVES: To determine the effects of tooth brushing on five bulk-fill resin based composites (RBCs). METHOD: Ten samples of Filtek Supreme Enamel (control), Filtek One Bulk Fill, Tetric EvoCeram Bulk Fill, SonicFill 2, SDR flow+, and Admira Fusion X-tra were light cured for 20 seconds using the Valo Grand curing light. After 24 hours storage in air at 37°C, specimens were brushed in a random order using Colgate OpticWhite dentifrice and a soft toothbrush. Surface gloss was measured prior to brushing, after 5,000, 10,000 and 15,000 back and forth brushing cycles...
December 5, 2017: Journal of Esthetic and Restorative Dentistry
https://www.readbyqxmd.com/read/29203487/role-of-smeu1vwu2x-operon-in-the-alleviation-of-oxidative-stresses-and-the-occurrence-of-sulfamethoxazole-trimethoprim-resistant-mutants-in-stenotrophomonas-maltophilia
#18
Chao-Jung Wu, Tsu-Ting Chiu, Yi-Tsung Lin, Yi-Wei Huang, Li-Hua Li, Tsuey-Ching Yang
Overexpression of resistance-nodulation-division (RND)-type efflux pumps is an important mechanism for bacteria to combat antimicrobials. RND efflux pumps are also critical for bacterial physiology such as oxidative stress tolerance. Stenotrophomonas maltophilia, a multi-drug resistant opportunistic pathogen, harbors eight RND-type efflux pump operons. Of them, smeU1VWU2X operon is unique for its possession of two additional genes, smeU1 and smeU2, which encode proteins of short-chain dehydrogenase/reductase (SDR) family...
December 4, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29202408/synthesis-and-antimycobacterial-activity-of-triterpeni%C3%A2-a-ring-azepanes
#19
Natalya I Medvedeva, Oxana B Kazakova, Tatyana V Lopatina, Irina E Smirnova, Gul'nara V Giniyatullina, Irina P Baikova, Vladimir E Kataev
A series of A-ring azepanones and azepanes derived from betulonic, oleanonic and ursonic acids was synthesized and evaluated for their in vitro antimycobacterial activities against M. tuberculosis (MTB) H37Rv and SDR-TB in the National Institute of Allergy and Infectious Diseases. Triterpenic A-azepano-28-hydroxy-derivatives were synthesized by the reduction with LiAlH4 of triterpenic azepanones available from the Beckmann rearrangement of the corresponding C3-oximes. Modification of azepanes at NH-group and atoms С12, C20, C28 and C29 of triterpenic core led to the derivatives with oxo, epoxy, aminopropyl, oximino and acyl substituents...
November 21, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29183673/effect-of-tribochemical-treatments-and-silane-reactivity-on-resin-bonding-to-zirconia
#20
Raphael Pilo, Maria Dimitriadi, Anna Palaghia, George Eliades
OBJECTIVE: The aim of the study was to assess the roughness, structure and bond strength with zirconia of four grit-blasting treatments combined with three silane types, the reactivity of which was evaluated, as well. METHODS: The grit-blasted treatments performed on zirconia (Lava) were alumina (ALU), CoJet (COJ), SilJet (SLJ) and SilJet Plus (SJP, with silica-encapsulated silane). The other two silanes selected were the S-Bond (SB, prehydrolyzed) and Clearfil Ceramic Primer Plus (CP, prehydrolyzed with 10-MDP)...
November 25, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
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