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https://www.readbyqxmd.com/read/28222209/effect-of-different-intermediary-bases-on-microleakage-of-a-restorative-material-in-class-ii-box-cavities-of-primary-teeth
#1
Faika Y Abdelmegid, Fouad S Salama, Waleed M Al-Mutairi, Saud K Al-Mutairi, Sultan O Baghazal
INTRODUCTION: The aim of this in vitro study was to assess and compare the effect of different intermediary bases on microleakage between tooth and a nanocomposite interface in Class II box cavities in primary teeth. METHODS: Standard Class II box cavities were prepared in 52 primary molars and randomly divided into 9 groups according to the intermediary base used (Multicore Flow, Fuji II LC, SDR, Smart Dentin Replacement, and Biodentine). All specimens were subjected to thermocycling and prepared for microleakage testing and evaluation...
February 21, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/28217913/what-are-the-key-elements-of-cognitive-analytic-therapy-for-psychosis-a-delphi-study
#2
Peter J Taylor, Sarah Jones, Christopher D Huntley, Claire Seddon
OBJECTIVE: There has been growing interest in the use of cognitive analytic therapy (CAT) with those facing experiences of psychosis. However, there is little research on how CAT is best applied to working with psychosis. This study aimed to identify what the key aspects of CAT for psychosis are or whether this approach requires adaptation when applied to those with experiences of psychosis, drawing on expert opinion. METHOD: An adapted Delphi methodology was used...
February 20, 2017: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/28214787/sparse-and-dense-hybrid-representation-via-subspace-modeling-for-dynamic-mri
#3
Qiegen Liu, Shanshan Wang, Dong Liang
Recent theoretical results on compressed sensing and low-rank matrix recovery have inspired significant interest in joint sparse and low rank modeling of dynamic magnetic resonance imaging (dMRI). Existing approaches usually describe these two respective prior information with different formulations. In this paper, we present a novel sparse and dense hybrid representation (SDR) model which describes the sparse plus low rank properties by a unified way. More specifically, under the learned dictionary consisting of temporal basis functions, SDR models the spatial coefficients in two subspaces with Laplacian and Gaussian prior distributions, respectively...
February 5, 2017: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/28187883/enhancement-of-lung-sounds-based-on-empirical-mode-decomposition-and-fourier-transform-algorithm
#4
Ashok Mondal, Poulami Banerjee, Ajay Somkuwar
BACKGROUND AND OBJECTIVE: There is always heart sound (HS) signal interfering during the recording of lung sound (LS) signals. This obscures the features of LS signals and creates confusion on pathological states, if any, of the lungs. In this work, a new method is proposed for reduction of heart sound interference which is based on empirical mode decomposition (EMD) technique and prediction algorithm. METHOD: In this approach, first the mixed signal is split into several components in terms of intrinsic mode functions (IMFs)...
February 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28179188/diacetyl-and-related-flavorant-%C3%AE-diketones-biotransformation-cellular-interactions-and-respiratory-tract-toxicity
#5
M W Anders
Exposure to diacetyl and related α-diketones causes respiratory-tract damage in humans and experimental animals. Chemical toxicity is often associated with covalent modification of cellular nucleophiles by electrophilic chemicals. Electrophilic α-diketones may covalently modify nucleophilic arginine residues in critical proteins and, thereby, produce the observed respiratory-tract pathology. The major pathway for the biotransformation of α-diketones is reduction to α-hydroxyketones (acyloins), which is catalyzed by NAD(P)H-dependent enzymes of the short-chain dehydrogenase/reductase (SDR) and the aldo-keto reductase (AKR) superfamilies...
February 5, 2017: Toxicology
https://www.readbyqxmd.com/read/28167628/exposure-to-a-social-stressor-induces-translocation-of-commensal-lactobacilli-to-the-spleen-and-priming-of-the-innate-immune-system
#6
William P Lafuse, Rachel Gearinger, Sydney Fisher, Connor Nealer, Amy R Mackos, Michael T Bailey
Studies have shown that exposure to psychological stressors leads to inflammation throughout the body. This has been widely studied using social disruption (SDR), a social stressor that involves repeated social defeat in subordinate mice. Exposure to SDR increases serum cytokine levels, results in accumulation of spleen CD11b(+) myeloid cells, and primes macrophages for increased cytokine and microbicidal activity. Our previous studies showed that intestinal microbes are necessary for SDR-enhancement of innate immunity...
February 6, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28158039/refractive-index-variance-of-cells-and-tissues-measured-by-quantitative-phase-imaging
#7
Mingguang Shan, Mikhail E Kandel, Gabriel Popescu
The refractive index distribution of cells and tissues governs their interaction with light and can report on morphological modifications associated with disease. Through intensity-based measurements, refractive index information can be extracted only via scattering models that approximate light propagation. As a result, current knowledge of refractive index distributions across various tissues and cell types remains limited. Here we use quantitative phase imaging and the statistical dispersion relation (SDR) to extract information about the refractive index variance in a variety of specimens...
January 23, 2017: Optics Express
https://www.readbyqxmd.com/read/28153571/providing-data-for-serrated-polyp-detection-rate-benchmarks-an-analysis-of-the-new-hampshire-colonoscopy-registry
#8
Joseph C Anderson, Lynn F Butterly, Julia E Weiss, Christina M Robinson
BACKGROUND AND AIMS: Similar to achieving adenoma detection rate (ADR) benchmarks to prevent colorectal cancer (CRC), achieving adequate serrated polyp detection rates (SDR) may be essential to the prevention of CRC associated with the serrated pathway. Previous studies have been based on data from high-volume endoscopists at single academic centers. Based on a hypothesis that ADR is correlated with SDR, we stratified a large, diverse group of endoscopists (n=77 practicing at 28 centers) into high and low performers based on ADR, to provide data for corresponding target SDR benchmarks...
January 30, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28144595/extraction-of-respiratory-signal-based-on-image-clustering-and-intensity-parameters-at-radiotherapy-with-external-beam-a-comparative-study
#9
P Samadi Miandoab, A Esmaili Torshabi, S Nankali
BACKGROUND: Since tumors located in thorax region of body mainly move due to respiration, in the modern radiotherapy, there have been many attempts such as; external markers, strain gage and spirometer represent for monitoring patients' breathing signal. With the advent of fluoroscopy technique, indirect methods were proposed as an alternative approach to extract patients' breathing signals. MATERIALS AND METHODS: The purpose of this study is to extract respiratory signals using two available methods based on clustering and intensity strategies on medical image dataset of XCAT phantom...
December 2016: Journal of Biomedical Physics & Engineering
https://www.readbyqxmd.com/read/28128053/the-%C3%AE-sheet-core-is-the-favored-candidate-of-engineering-sdr-for-enhancing-thermostability-but-not-for-activity
#10
Deshuai Lou, Jun Tan, Liancai Zhu, Shunlin Ji, Bochu Wang
7α-Hydroxysteroid dehydrogenases (7α-HSDHs) can stereoselectively catalyze steroids, aromatic α-ketoesters, and benzaldehyde analogues playing a critical role in the biotransformation and poor thermostability that hinders their biomedical and industrial applications. Based on the three-dimensional structure of 7α-HSDH from Clostridium absonum (CA 7α-HSDH), recently reported program MAESTRO was used to compute the ΔΔG and predict the single-point mutants that could enhance its thermostability. Four mutants were selected and verified experimentally...
January 26, 2017: Protein and Peptide Letters
https://www.readbyqxmd.com/read/28125217/functional-and-evolutionary-characterization-of-a-udp-xylose-synthase-gene-from-the-plant-pathogen-xylella-fastidiosa-involved-in-the-synthesis-of-bacterial-lipopolysaccharide
#11
Valquíria Campos Alencar, Daniela Leite Jabes, Fabiano Bezerra Menegidio, Guilherme Lanzi Sassaki, Lucas Rodrigo de Souza, Luciano Puzer, Maria Cecília Zorél Meneghetti, Marcelo Andrade Lima, Ivarne Luis Dos Santos Tersariol, Regina Costa de Oliveira, Luiz R Nunes
Xylella fastidiosa is a plant-infecting bacillus, responsible for many important crop diseases, such as Pierce's disease of vineyards, citrus variegated chlorosis, and coffee leaf scorch (CLS), among others. Recent genomic comparisons involving two CLS-related strains, belonging to X. fastidiosa subsp. pauca, revealed that one of them carries a frameshift mutation that inactivates a gene encoding an oxidoreductase of the short-chain dehydrogenase/reductase (SDR) superfamily, which may play important roles in determining structural variations in bacterial glycans and glycoconjugates...
January 26, 2017: Biochemistry
https://www.readbyqxmd.com/read/28107498/delineating-substrate-diversity-of-disparate-short-chain-dehydrogenase-reductase-from-debaryomyces-hansenii
#12
Arindam Ghatak, Nagakumar Bharatham, Anirudh P Shanbhag, Santanu Datta, Janani Venkatraman
Short-chain dehydrogenase reductases (SDRs) have been utilized for catalyzing the reduction of many aromatic/aliphatic prochiral ketones to their respective alcohols. However, there is a paucity of data that elucidates their innate biological role and diverse substrate space. In this study, we executed an in-depth biochemical characterization and substrate space mapping (with 278 prochiral ketones) of an unannotated SDR (DHK) from Debaryomyces hansenii and compared it with structurally and functionally characterized SDR Synechococcus elongatus...
2017: PloS One
https://www.readbyqxmd.com/read/28091437/radiopacity-of-bulk-fill-flowable-resin-composite-materials
#13
T Yildirim, M K Ayar, M S Akdag, C Yesilyurt
OBJECTIVES: The purpose of this study was to evaluate the radiopacity of currently marketed bulk fill flowable dental composite materials (Beautifil Bulk Flowable, SDR Flow, Filtek Bulk Fill Flow, and x-tra Base Bulk Fill). MATERIALS AND METHODS: Six specimens of each material with a thickness of 1 mm were prepared, and digital radiographs were taken, using a CCD sensor along with an aluminum stepwedge and 1 mm-thick tooth slice. The mean gray level of each aluminum stepwedge and selected materials was measured, using the equal-density area tool of Kodak Dental Imaging software...
February 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28088459/strain-development-in-bulk-filled-cavities-of-different-depths-characterized-using-a-non-destructive-acoustic-emission-approach
#14
Annelies Van Ende, Diogo Pedrollo Lise, Jan De Munck, Johan Vanhulst, Martine Wevers, Bart Van Meerbeek
OBJECTIVES: (1) To evaluate the effect of cavity depth and composite type on the interfacial debonding in bulk-filled cavities. (2) To correlate the theoretical shrinkage stress and the level of interfacial debonding determined by acoustic emission (AE). METHODS: 80 sound molars were divided in two groups to receive a Class-I cavity (3.5×3.5mm) with 2.5- or 4.0-mm depth. The cavities were restored with either a conventional paste-like (Filtek Z100, 3M ESPE), a conventional flowable (G-ænial Universal Flo, GC), a bulk-fill paste-like (Tetric EvoCeram Bulk Fill, Ivoclar Vivadent) or a bulk-fill flowable (SDR, Dentsply) composite (n=10)...
January 11, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28076679/molecular-dynamics-simulations-for-deciphering-the-structural-basis-of-recognition-of-pre-let-7-mirnas-by-lin28
#15
Chhaya Sharma, Debasisa Mohanty
LIN28 protein inhibits biogenesis of miRNAs belonging to the let-7 family by binding to precursor forms of miRNAs. Overexpression of LIN28 and low levels of let-7 miRNAs are associated with several forms of cancer cells. We have performed multiple explicit solvent molecular dynamics simulations ranging from 200 to 500 ns in length on different isoforms of preE-let-7 in complex with LIN28 and also in isolation to identify structural features and key specificity-determining residues (SDRs) that are important for the inhibitory role of LIN28...
January 24, 2017: Biochemistry
https://www.readbyqxmd.com/read/28075345/software-defined-doppler-radar-as-a-contactless-multipurpose-microwave-sensor-for-vibrations-monitoring
#16
Antonio Raffo, Sandra Costanzo, Giuseppe Di Massa
A vibration sensor based on the use of a Software-Defined Radio (SDR) platform is adopted in this work to provide a contactless and multipurpose solution for low-cost real-time vibrations monitoring. In order to test the vibration detection ability of the proposed non-contact method, a 1 GHz Doppler radar sensor is simulated and successfully assessed on targets at various distances, with various oscillation frequencies and amplitudes. Furthermore, an SDR Doppler platform is practically realized, and preliminary experimental validations on a device able to produce a harmonic motion are illustrated to prove the effectiveness of the proposed approach...
January 8, 2017: Sensors
https://www.readbyqxmd.com/read/28059941/adenoma-detection-rates-for-screening-colonoscopies-in-smokers-and-obese-adults-data-from-the-new-hampshire-colonoscopy-registry
#17
Joseph C Anderson, Julia E Weiss, Christina M Robinson, Lynn F Butterly
GOAL: To examine screening adenoma detection rates (ADR) and serrated detection rates (SDR) among smokers and obese adults in the New Hampshire Colonoscopy Registry. BACKGROUND: ADR, a quality measure for screening colonoscopies, is associated with protection from interval colorectal cancer. Currently, only sex-specific ADR benchmarks are reported. However, obesity and smoking ≥20 pack-years are strong predictors for colorectal neoplasia, as highlighted by the 2009 American College of Gastroenterology CRC Screening Guidelines...
January 5, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28033498/a-robust-approach-to-apodization-design-in-phased-arrays-for-ultrasound-imaging
#18
Amir Gholampour, Sayed Mahmoud Sakhaei, Seyed Mehdi Hosseini Andargoli
Apodization is a common way to control the sidelobe level of the beampattern. To design the apodization, it is usually assumed that the medium is homogenous with a fixed value of sound speed, despite the fact that the speed may vary by a great value in practical situations. On the other hand, the beamforming performance is highly affected by the speed value. In this paper, the beampattern sensitivity to the speed variations is firstly investigated through both mathematical representations and simulation results showing that the speed errors lead to a sever degradation of the beampattern in terms of both mainlobe width and sidelobe level...
December 16, 2016: Ultrasonics
https://www.readbyqxmd.com/read/28007336/the-combined-frequency-of-igf-and-myostatin-polymorphism-among-track-field-athletes-and-swimmers
#19
Sigal Ben-Zaken, Yoav Meckel, Dan Nemet, Alon Eliakim
OBJECTIVE: The IGF C-1245T (rs35767) and the myostatin (MSTN) Lys(K)-153Arg(R) genetic polymorphism may influence skeletal muscle phenotypes and athletic performance. Carrying the minor IGF T allele and the myostatin rare R allele was associated with higher circulating IGF-I levels, greater muscle mass and improved performance. The aim of the present study was to assess the combined frequency of the IGF 1245T (rs35767) and MSTN 153Arg(R) polymorphism among Israeli track and field athletes (n=111) and swimmers (n=80)...
December 15, 2016: Growth Hormone & IGF Research
https://www.readbyqxmd.com/read/28005671/hyperspectral-autofluorescence-imaging-of-drusen-and-retinal-pigment-epithelium-in-donor-eyes-with-age-related-macular-degeneration
#20
Yuehong Tong, Tal Ben Ami, Sungmin Hong, Rainer Heintzmann, Guido Gerig, Zsolt Ablonczy, Christine A Curcio, Thomas Ach, R Theodore Smith
PURPOSE: To elucidate the molecular pathogenesis of age-related macular degeneration (AMD) and interpretation of fundus autofluorescence imaging, the authors identified spectral autofluorescence characteristics of drusen and retinal pigment epithelium (RPE) in donor eyes with AMD. METHODS: Macular RPE/Bruch membrane flat mounts were prepared from 5 donor eyes with AMD. In 12 locations (1-3 per eye), hyperspectral autofluorescence images in 10-nm-wavelength steps were acquired at 2 excitation wavelengths (λex 436, 480 nm)...
December 2016: Retina
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