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Fabiane de Amorim Almeida, Mariana Salim de Moraes, Mariana Lucas da Rocha Cunha
OBJECTIVE: To understand the experiences of nurses when caring for dying newborns and their families in the NICU; and redeem their perceptions about acting before the death and grieving process. METHOD: A descriptive exploratory study with a qualitative approach, developed with nine nurses at the ICU of a hospital in São Paulo (SP), Brazil. Data was collected through semi-structured interviews and analyzed using the Collective Subject Discourse (CSD). RESULTS: Caring for newborns who are dying and their families is very difficult for nurses, due to the intense involvement...
June 2016: Revista da Escola de Enfermagem da U S P
R Paul Bardos, Sarah Jones, Ian Stephenson, Pierre Menger, Victor Beumer, Francesca Neonato, Linda Maring, Uwe Ferber, Thomas Track, Katja Wendler
Soft re-use of brownfields describes intended temporary or final re-uses of brownfield sites which are not based on built constructions or infrastructure ('hard' re-use). Examples of soft re-uses include the creation of public green space. These are essentially uses where the soil is not sealed. Often the case for soft re-use of brownfields has not been easy to demonstrate in strictly financial terms. The purpose of this paper is to describe a value based approach to identify and optimise services provided by the restoration of brownfields to soft re-uses, on a permanent or interim basis...
September 1, 2016: Science of the Total Environment
P Bagolan
Congenital diaphragmatic hernia (CDH) is one of the most serious and controversial congenital anomalies. Pulmonary hypoplasia with/without pulmonary hypertension (and major associated anomalies) are reported the main causes of death in these patients. New treatment strategies for CDH have allowed an increase of survival also of more severe patients. As a consequence many attentions are now focused on long term follow up of these delicate babies. Many reports, in the last years, have highlighted associated morbidities in CDH survivors, such as pulmonary sequelae, neurodevelopmental delay, auxological deficits, gastrointestinal and orthopedic disorders...
June 2010: Minerva Pediatrica
F Tandoi, M Agosti
No abstract text is available yet for this article.
June 2010: Minerva Pediatrica
A Leaf
AIM: Pregnancies complicated by abnormal antenatal Doppler blood flow often result in the preterm delivery of a growth restricted baby. These babies have a high risk of milk intolerance and necrotising enterocolitis (1), and introduction of milk feeds is frequently delayed. Our aim was to determine the effect of early or late introduction on success of achieving full milk feeds and on adverse outcomes including NEC. METHODS: Eligible babies with birthweight below 10th centile and gestation below 34+6 weeks, born after abnormal antenatal Dopplers, were randomised between 20 and 48 hours to either early (24-48 hours) or late (120-144 hours) introduction of milk feeds...
June 2010: Minerva Pediatrica
Miguel Eloy Torcida González, Ricardo J Hernández Herrera, Mauro Ochoa Torres, Luis Fernando Ramírez Sánchez
Polycystic kidney disease is a common genetic cause of chronic kidney disease, characterized by the formation of multiple cysts in the kidneys and other organs, occurs in 1 in 20,000 live births. 30 to 50% of affected newborns die shortly after birth because of respiratory and renal insufficiency. This study reports the case of a newborn with polycystic kidney disease diagnosed by obstetric ultrasound at 26 weeks of gestation and kidneys anhidramnios due to increased volume and appearance "in sponge." Neonato a primigravida 19 years of age...
May 2009: Ginecología y Obstetricia de México
Françoise Bernaudin, Suzanne Verlhac, Sylvie Chevret, Martine Torres, Lena Coic, Cécile Arnaud, Annie Kamdem, Isabelle Hau, Maria Grazia Neonato, Christophe Delacourt
Stroke is predicted by abnormally high cerebral velocities by transcranial doppler (TCD). This study aimed at defining predictive factors for abnormally high velocities (>/= 2 m/sec) based on the Créteil pediatric sickle cell anemia (SCA) cohort composed of 373 stroke-free SCA children. alpha genes and beta-globin haplotypes were determined. Biologic parameters were obtained at baseline. alpha-thalassemia was present in 155 of 325 and G6PD deficiency in 36 of 325 evaluated patients. TCD was abnormal in 62 of 373 patients...
November 15, 2008: Blood
P Lago, G Ancora, C V Bellieni, A Cavazza, G Cocchi, A M Guadagni, L Memo, D Merazzi, A Pirelli
OBJECTIVE: Despite accumulating evidence that procedural pain experienced by preterm infants may have acute detrimental and even long-term effects on an infant's subsequent behavior and neurological outcome, neonates admitted to Neonatal Intensive Care Units still frequently experience acute and prolonged uncontrolled pain. Many invasive and surgical procedures are routinely performed at the bedside in the NICU without adequate pain management. AIM: To develop evidence-based guidelines and recommendations for pain control and prevention in Italian i...
2006: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
Ming Li, Cheng-yu Huang, Xiang-dong Wang, Xing-hui Liu
OBJECTIVE: The purpose of the study is to determine primarily the concentration of plasma copper and collagen in fetal membrane of the preterm's mothers, and explore the relation of copper status and fetal membrane collagen of preterm's mothers. METHODS: The general situations were collected both in neonatos and their mothers. The plasma copper concentrations of mother venous blood and cord blood were analyzed by ICP-OES. Sirius Red dyeing was first used in fetal membrane to detect the thickness and collagen in preterm's and full-term's mothers...
July 2006: Wei Sheng Yan Jiu, Journal of Hygiene Research
Micheline Maier-Redelsperger, Antoine Flahault, Maria Grazia Neonato, Robert Girot, Dominique Labie
Phenotypic expression of sickle cell disease (SCD) is highly variable. We investigated red blood cells (RBCs) and reticulocytes using a laser light scattering method (ADVIA120, Bayer Diagnostics, Tarrytown, NY) in a series of patients with either sickle cell anemia (SS) or compound SC heterozygosity (SC), both groups with or without alpha thalassemia. Results were compared with those of a series of patients without hematological disease. Known data were consistently confirmed, namely heterogeneity in cell volume and hemoglobin (Hb) concentration, as well as the premature exit of "stress" reticulocytes from the bone marrow, mostly in SS patients...
July 2004: Blood Cells, Molecules & Diseases
No abstract text is available yet for this article.
April 15, 1965: Gazzetta Internazionale di Medicina e Chirurgia
No abstract text is available yet for this article.
June 1965: Archivio "E. Maragliano" di Patologia e Clinica
R Tamouza, R Sghiri, R Ramasawmy, M G Neonato, L E Mombo, J C Poirier, V Schaeffer, C Fortier, D Labie, R Girot, A Toubert, R Krishnamoorthy, D Charron
CD1 gene (CD1A to CD1E) products are involved in non-peptide antigen presentation, such as lipids and glycolipids, to T cells. With a similar function to MHC, namely antigen presentation, these genes nevertheless displayed a much lower level of polymorphism as compared to MHC. We report here two additional CD1E variants identified in black African individuals, designated herein CD1E*05 and CD1E*06. While the former differs from the common (wild type) allele sequence by two substitutions at nucleotide positions 217 and 229 of exon 2, the latter only by a single base change at position 91 of exon 3...
May 2002: Tissue Antigens
Ryad Tamouza, Maria Grazia Neonato, Marc Busson, François Marzais, Robert Girot, Dominique Labie, Jacques Elion, Dominique Charron
Despite systematic antibiotic therapy, severe infections (septicemia, meningitis, or osteomyelitis) are a major cause of mortality and morbidity in children with sickle cell disease (SCD). In this study, we explored the possibility that polymorphism at the human leukocyte antigen (HLA) locus might constitute an immunogenetic modifying factor to the intrinsic susceptibility to infection in patients with SCD. A cohort of 80 SCD patients living in Paris, 43 with at least one major infectious complication and 37 without infections, were typed for HLA class II loci by polymerase chain reaction-sequence-specific primers (PCR-SSP)...
March 2002: Human Immunology
B Chaine, M G Neonato, R Girot, S Aractingi
BACKGROUND: Treatment with hydroxyurea may alleviate the symptoms of sickle cell disease (SCD). Because treatment with hydroxyurea may be responsible for several cutaneous side effects and is often lifelong in patients with SCD, we conducted this study to evaluate the risk of cutaneous adverse reactions in SCD patients treated with hydroxyurea. OBSERVATIONS: Seventeen adult patients with SCD treated with hydroxyurea at one institution were examined by a dermatologist...
April 2001: Archives of Dermatology
M G Neonato, M Guilloud-Bataille, P Beauvais, P Bégué, M Belloy, M Benkerrou, R Ducrocq, M Maier-Redelsperger, M de Montalembert, B Quinet, J Elion, J Feingold, R Girot
A subset of 299 patients with homozygous sickle cell anaemia, enrolled in the cohort of the French Study Group on sickle cell disease (SCD), was investigated in this study. The majority of patients were children (mean age 10.1 +/- 5.8 yr) of first generation immigrants from Western and Central Africa, the others originated from the French West Indies (20.2%). We report the frequency of the main clinical events (mean follow-up 4.2 +/- 2.2 yr). The prevalence of meningitis-septicaemia and osteomyelitis was, respectively, 11...
September 2000: European Journal of Haematology
C Hernández-Guerrero, J Tenorio-Ramos, F Vadillo-Ortega, F Arechavaleta-Velasco, L Jiménez-Zamudio, J R Ahued-Ahued, J Beltrán-Montoya, C Neri-Méndez
Neonato preterm birth (before 37 pregnancy weeks) account more than 80% perinatal deaths not attributable to congenital malformations. Preterm and term labor full mechanisms are unknown at present. Proinflammatory cytokinesis direct participation have been involved in the phenomena by several experimental evidence. The study's aim was to determine TNF-alpha and IL-1 beta concentration at maternal, fetal and fetal-maternal vascular compartments in women with term and preterm delivery and in women at term childbirth without labor...
March 2000: Ginecología y Obstetricia de México
M G Neonato, C Y Lu, M Guilloud-Bataille, C Lapouméroulie, H Nabeel-Jassim, D Dabit, R Girot, R Krishnamoorthy, J Feingold, C Besmond, J Elion
Mannose-binding protein (MBP) is a serum lectin that participates in the innate immune response. MBP deficiency may constitute a risk factor in the development of infections. Three MBP structural variants have been identified with a dominant effect on MBP serum concentration. Similarly, polymorphisms in the promoter of the corresponding gene (HSMBP1B) have been related to variations of MBP concentration in serum. Children with sickle cell disease (SCD) have an increased susceptibility to infections with encapsulated organisms resulting in meningitis, septicaemia, and osteomyelitis...
September 1999: European Journal of Human Genetics: EJHG
M Maier-Redelsperger, M de Montalembert, A Flahault, M G Neonato, R Ducrocq, M P Masson, R Girot, J Elion
We have studied the cellular and molecular responses to long-term hydroxyurea (HU) treatment in 29 severely affected young patients with sickle cell disease (mean age, 10.9 +/- 4.1 years). Patients received HU at 20 mg/kg/d on 4 consecutive days per week initially, with a monthly escalated dose avoiding marrow-toxicity (mean steady-state dose, 34.2 +/- 4.6 mg/kg/d) for 12 to 36 months (mean duration, 22 months). The studied parameters were hemoglobin F (HbF), F reticulocytes (F retics), F cells, the amount of HbF per F cell (F/F cell), polymer tendency at 40% and 70% oxygen saturation, and hemolysis...
June 15, 1998: Blood
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