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chronic postthoracotomy pain

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https://www.readbyqxmd.com/read/27916242/the-effect-of-pregabalin-and-methylcobalamin-combination-on-the-chronic-postthoracotomy-pain-syndrome
#1
Serda Kanbur Metin, Burhan Meydan, Serdar Evman, Talha Dogruyol, Volkan Baysungur
BACKGROUND: Chronic postthoracotomy pain (CPTP) consists of different types of pain. Some characteristics of CPTP are the same as those of recognized neuropathic pain syndromes. We aimed to determine the safety and efficacy of pregabalin and methylcobalamin combination (PG-B12) in comparison with diclofenac potassium (DP) in patients with CPTP. METHODS: One hundred consecutive patients with CPTP after posterolateral/lateral thoracotomy were prospectively randomly assigned and evaluated...
December 1, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27871525/a-retrospective-study-of-open-thoracotomies-versus-thoracoscopic-surgeries-for-persistent-postthoracotomy-pain
#2
Harsha Shanthanna, Dina Aboutouk, Eugenia Poon, Ji Cheng, Christian Finley, James Paul, Lehana Thabane
OBJECTIVE: Persistent thoracotomy pain syndrome (PTPS) is a recognized complication and is considered to be less after video-assisted thoracoscopic surgery (VATS) compared with open thoracic surgery (OTS). The primary objective was to compare the incidence of PTPS at 6 months. Secondary objectives were to compare the incidence of neuropathic pain between VATS and OTS and to report perioperative factors associated with the development of PTPS. METHODS: This historical cohort study involved patient contact by a questionnaire regarding the presence of PTPS and its type...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/26116369/spontaneous-chronic-pain-after-experimental-thoracotomy-revealed-by-conditioned-place-preference-morphine-differentiates-tactile-evoked-pain-from-spontaneous-pain
#3
Ching-Hsia Hung, Jeffrey Chi-Fei Wang, Gary R Strichartz
Chronic pain after surgery limits social activity, interferes with work, and causes emotional suffering. A major component of such pain is reported as resting or spontaneous pain with no apparent external stimulus. Although experimental animal models can simulate the stimulus-evoked chronic pain that occurs after surgery, there have been no studies of spontaneous chronic pain in such models. Here the conditioned place preference (CPP) paradigm was used to reveal resting pain after experimental thoracotomy. Male Sprague Dawley rats received a thoracotomy with 1-hour rib retraction, resulting in evoked tactile hypersensitivity, previously shown to last for at least 9 weeks...
September 2015: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/25899956/impact-of-pregabalin-on-the-occurrence-of-postthoracotomy-pain-syndrome-a-randomized-trial
#4
RANDOMIZED CONTROLLED TRIAL
Véronique Brulotte, Monique M Ruel, Edwin Lafontaine, Philippe Chouinard, François Girard
BACKGROUND: Postthoracotomy pain syndrome (PTPS) is a frequent cause of chronic postoperative pain. Pregabalin might reduce the incidence of chronic postoperative pain. The goal of this study was to evaluate the impact of perioperative pregabalin on the occurrence of PTPS, defined as any surgical site pain 3 months after surgery. METHODS: We conducted a randomized, placebo-controlled, double-blind trial in patients undergoing elective thoracotomy. Patients received either pregabalin 150 mg orally twice a day initiated 1 hour before thoracotomy and continued until 4 days after thoracotomy (10 doses total) or a placebo using the same protocol...
May 2015: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/25281929/expectations-and-positive-emotional-feelings-accompany-reductions-in-ongoing-and-evoked-neuropathic-pain-following-placebo-interventions
#5
Gitte L Petersen, Nanna B Finnerup, Kasper Grosen, Hans K Pilegaard, Irene Tracey, Fabrizio Benedetti, Donald D Price, Troels S Jensen, Lene Vase
Research on placebo analgesia and nocebo hyperalgesia has primarily included healthy subjects or acute pain patients, and it is unknown whether these effects can be obtained in ongoing pain in patients with chronic pain caused by an identifiable nerve injury. Eighteen patients with postthoracotomy neuropathic pain were exposed to placebo and nocebo manipulations, in which they received open and hidden administrations of pain-relieving (lidocaine) or pain-inducing (capsaicin) treatment controlled for the natural history of pain...
December 2014: Pain
https://www.readbyqxmd.com/read/24799159/chronic-postthoracotomy-pain-and-perioperative-ketamine-infusion
#6
RANDOMIZED CONTROLLED TRIAL
Jie Hu, Qin Liao, Fan Zhang, Jianbin Tong, Wen Ouyang
The objectives of this study were to investigate whether continuous intravenous ketamine during the first 72 hours after thoracotomy could reduce the incidence and intensity of chronic postthoracotomy pain (CPTP) and to define the incidence and risk factors of CPTP. Seventy-eight patients receiving thoracotomy for lung tumor (benign or malignant) were randomly divided into two groups: ketamine group (n = 31) and control groups (n = 47). Patients in the ketamine group received intravenous ketamine 1 mg/kg before incision, followed by 2 μg/kg/minute infusion for 72 hours plus sufentanil patient-controlled intravenous analgesia after thoracotomy...
June 2014: Journal of Pain & Palliative Care Pharmacotherapy
https://www.readbyqxmd.com/read/24525274/quantitative-sensory-testing-in-the-german-research-network-on-neuropathic-pain-dfns-reference-data-for-the-trunk-and-application-in-patients-with-chronic-postherpetic-neuralgia
#7
Doreen B Pfau, Elena K Krumova, Rolf-Detlef Treede, Ralf Baron, Thomas Toelle, Frank Birklein, Wolfgang Eich, Christian Geber, Andreas Gerhardt, Thomas Weiss, Walter Magerl, Christoph Maier
Age- and gender-matched reference values are essential for the clinical use of quantitative sensory testing (QST). To extend the standard test sites for QST-according to the German Research Network on Neuropathic Pain-to the trunk, we collected QST profiles on the back in 162 healthy subjects. Sensory profiles for standard test sites were within normal interlaboratory differences. QST revealed lower sensitivity on the upper back than the hand, and higher sensitivity on the lower back than the foot, but no systematic differences between these trunk sites...
May 2014: Pain
https://www.readbyqxmd.com/read/24385221/preoperat%C3%A4-ve-ultrasound-gu%C3%A4-ded-suprascapular-nerve-block-for-postthoracotomy-shoulder-pa%C3%A4-n
#8
Emine Ozyuvaci, Onat Akyol, Tolga Sitilci, Türkan Dübüs, Hakan Topac Ogˇlu, Hülya Leblebici, Alican Ac Ikgöz
BACKGROUND: Acute postthoracotomy pain is a well-known potential problem, with pulmonary complications, ineffective respiratory rehabilitation, and delayed mobilization in the initial postoperative period, and it is followed by chronic pain. The type of thoracotomy, intercostal nerve damage, muscle retraction, costal fractures, pleural irritation, and incision scar are the most responsible mechanisms. OBJECTIVE: Our aim was to assess whether preoperative ultrasound suprascapular nerve block with thoracic epidural analgesia was effective for postthoracotomy shoulder pain relief...
June 2013: Current Therapeutic Research, Clinical and Experimental
https://www.readbyqxmd.com/read/24235971/supraventricular-arrhythmias-after-thoracotomy-is-there-a-role-for-autonomic-imbalance
#9
REVIEW
George Vretzakis, Marina Simeoforidou, Konstantinos Stamoulis, Metaxia Bareka
Supraventricular arrhythmias are common rhythm disturbances following pulmonary surgery. The overall incidence varies between 3.2% and 30% in the literature, while atrial fibrillation is the most common form. These arrhythmias usually have an uneventful clinical course and revert to normal sinus rhythm, usually before patent's discharge from hospital. Their importance lies in the immediate hemodynamic consequences, the potential for systemic embolization and the consequent long-term need for prophylactic drug administration, and the increased cost of hospitalization...
2013: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/24145805/minimal-incidence-of-chronic-and-neuropathic-postthoracotomy-pain-after-anteroaxillary-thoracotomy-with-consequent-systemic-pain-therapy
#10
Sandra Kampe, Dirk Lüttecke, Karsten Wolter, Danjouma H Cheufou, Georgios Stamatis
No abstract text is available yet for this article.
September 2014: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/23328341/quantitative-sensory-testing-in-patients-with-postthoracotomy-pain-syndrome-part-2-variability-in-thermal-threshold-assessments
#11
Kim Wildgaard, Thomas K Ringsted, Henrik Kehlet, Mads U Werner
OBJECTIVES: Quantitative sensory testing is a reference method for characterization of postsurgical neuropathic components. Correct interpretation of data requires detailed information concerning the validity of the testing methods. The objective of the study was to assess the test-retest variability of thermal thresholds in patients (n = 14) with the postthoracotomy pain syndrome. METHODS: Sensory mapping with a metal roller (25°C) on the surgical side delineated an area with cool sensory dysfunction...
September 2013: Clinical Journal of Pain
https://www.readbyqxmd.com/read/22397986/chronic-postthoracotomy-pain-and-health-related-quality-of-life
#12
RANDOMIZED CONTROLLED TRIAL
Michelle A O Kinney, W Michael Hooten, Stephen D Cassivi, Mark S Allen, Melissa A Passe, Andrew C Hanson, Darrell R Schroeder, Carlos B Mantilla
BACKGROUND: Pain after thoracotomy is common. The objective of this study was to assess whether pain 3 months postthoracotomy negatively impacts quality of life. METHODS: One hundred ten patients were prospectively assessed using the Medical Outcomes Study 36-Item Short Form Health Survey before and 3 months after elective thoracotomy. Pain and medication use were evaluated by questionnaire. Patients experiencing pain at 3 months were compared with patients who did not have postthoracotomy pain...
April 2012: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/22341139/spinal-cord-stimulation-to-treat-postthoracotomy-neuralgia-non-small-cell-lung-cancer-a-case-report
#13
REVIEW
Kevin L Wininger, Michelle L Bester, Kedar K Deshpande
Surgery is the mainstay of therapy for resectable-type tumors associated with non-small-cell lung cancer. Today, thoracotomy and video-assisted thoracotomy are surgical options. The prevalence of chronic pain with neuropathic symptoms is relatively high after thoracotomy. Spinal cord stimulation to treat such pain has received limited attention in the literature. The aim of this article is to report on the use of spinal cord stimulation in a single case of neuralgia after thoracotomy with lobectomy to treat non-small-cell lung cancer...
March 2012: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/21705872/neurophysiological-characterization-of-persistent-postthoracotomy-pain
#14
Kim Wildgaard, Thomas Kamm Ringsted, Eske Kvanner Aasvang, Jesper Ravn, Mads Utke Werner, Henrik Kehlet
OBJECTIVES: The postthoracotomy pain syndrome (PTPS) has a prevalence of 30% to 40%. Although intraoperative nerve damage during thoracotomy has been demonstrated, it has not been clearly linked to PTPS and detailed quantitative sensory characterization data have so far not been presented, comparing PTPS and pain-free patients. METHODS: Neurophysiological characterization was performed in 17 patients with PTPS and 24 pain-free postthoracotomy patients using a detailed quantitative sensory testing protocol and psychometric questionnaires...
February 2012: Clinical Journal of Pain
https://www.readbyqxmd.com/read/21178605/preemptive-low-dose-epidural-ketamine-for-preventing-chronic-postthoracotomy-pain-a-prospective-double-blinded-randomized-clinical-trial
#15
RANDOMIZED CONTROLLED TRIAL
Ho-Geol Ryu, Chul-Joong Lee, Young-Tae Kim, Jae-Hyon Bahk
OBJECTIVES: Chronic postthoracotomy pain is the most common long-term complication that occurs after a thoracotomy with a reported incidence of up to 80%. Although thoracic epidural analgesia is a widely used method for managing acute postthoracotomy pain, its effects seems questionable. The objective of this prospective, double-blinded, randomized, controlled trial was to assess the effect of preemptive low-dose epidural ketamine in addition to preemptive thoracic epidural analgesia on the incidence of chronic postthoracotomy pain...
May 2011: Clinical Journal of Pain
https://www.readbyqxmd.com/read/21109140/subcutaneous-targeted-neuromodulation-technique-for-the-treatment-of-intractable-chronic-postthoracotomy-pain
#16
Panos Theodosiadis, Vasilios Grosomanidis, Efthimios Samoladas, Byron E Chalidis
Subcutaneous targeted neuromodulation has been used successfully in chronic neuropathic pain. A 26 year-old patient with severe postthoracotomy pain and ipsilateral "wing scapula" due to intraoperative injury of the long thoracic nerve, is reported. Application of targeted neuromodulation resulted in immediate pain relief and marked improvement of shoulder function at one-year follow-up. The technique may be an effective alternative treatment of chronic and intractable postoperative painful conditions.
December 2010: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/19933535/the-effects-of-resiniferatoxin-in-an-experimental-rat-thoracotomy-model
#17
Jin-Woo Shin, Carlo Pancaro, Chi Fei Wang, Peter Gerner
BACKGROUND: Chronic pain after thoracotomy has been reproduced in a rat model that allows investigation of drugs that might reduce the incidence of allodynia after thoracotomy. Previous studies suggest that morphine, clonidine, neostigmine, gabapentin, and bupivacaine reduce the incidence of allodynia in the rat postthoracotomy pain model. One purpose of this study was to test whether intercostal injection of resiniferatoxin (RTX) decreased the amount of allodynia in an animal model of chronic postthoracotomy pain...
January 1, 2010: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/18931216/low-dose-systemic-bupivacaine-prevents-the-development-of-allodynia-after-thoracotomy-in-rats
#18
Jin Woo Shin, Carlo Pancaro, Chi Fei Wang, Peter Gerner
BACKGROUND: Chronic pain after thoracotomy has been recently reproduced in a rat model that allows investigation of the effect of drugs that might reduce the incidence of allodynia after thoracotomy. Previous studies suggest that intrathecal or systemic morphine, clonidine, neostigmine, and gabapentin reduce the incidence of allodynia in the rat postthoracotomy pain model. Our purpose was to test whether intercostal and systemic injection of bupivacaine prevented the development of allodynia in an animal model of chronic intercostal neuropathic pain...
November 2008: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/18456220/postthoracotomy-paravertebral-analgesia-will-it-replace-epidural-analgesia
#19
REVIEW
Niamh P Conlon, Andrew D Shaw, Katherine P Grichnik
Thoracotomy is associated with significant acute postoperative pain and a high incidence of development of chronic pain. Thoracic epidural analgesia has long been standard treatment for postthoracotomy pain, but recently there has been increased interest in alternative regional techniques, particularly paravertebral analgesia. This article compares the analgesic efficacy, side effects, complications of, and contraindications for thoracic epidural and paravertebral analgesia techniques and discusses their effects on the development of chronic postthoracotomy pain...
June 2008: Anesthesiology Clinics
https://www.readbyqxmd.com/read/18456219/postthoracotomy-pain-management-problems
#20
REVIEW
Peter Gerner
Pain after thoracotomy is very severe, probably the most severe pain experienced after surgery. Thoracic epidural analgesia has greatly improved the pain experience and its consequences and has been considered the standard for pain management after thoracotomy. This view has been challenged recently by the use of paravertebral nerve blocks. Nevertheless, severe ipsilateral shoulder pain and the prevention of the postthoracotomy pain syndrome remain the most important challenges for management of postthoracotomy pain...
June 2008: Anesthesiology Clinics
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