Lorenzo Cortese, Pablo Fenández Esteberena, Marta Zanoletti, Giuseppe Lo Presti, Gloria Aranda Velazquez, Sabina Ruiz Janer, Mauro Buttafava, Marco Renna, Laura Di Sieno, Alberto Tosi, Alberto Dalla Mora, Stanislaw Wojtkiewicz, Hamid Dehghani, Sixte de Fraguier, An Nguyen-Dinh, Bogdan Rosinski, Udo M Weigel, Jaume Mesquida, Mattia Squarcia, Felicia A Hanzu, Davide Contini, Mireia Mora Porta, Turgut Durduran
Objective. 
In this paper, we present a detailed in vivo characterization of the optical and hemodynamic properties of the human sternocleidomastoid muscle (SCM), obtained through ultrasound-guided near-infrared time-domain and diffuse correlation spectroscopies.
 Approach. 
A total of sixty-five subjects (forty-nine females, sixteen males) among healthy volunteers and thyroid nodule patients have been recruited for the study. Their SCM hemodynamic (oxy-, deoxy- and total hemoglobin concentrations, blood flow, blood oxygen saturation and metabolic rate of oxygen extraction) and optical properties (wavelength dependent absorption and reduced scattering coefficients) have been measured by the use of a novel hybrid device combining in a single unit time-domain near-infrared spectroscopy, diffuse correlation spectroscopy and simultaneous ultrasound imaging...
December 7, 2023: Physiological Measurement