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Carnicetine

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https://www.readbyqxmd.com/read/26356394/-optimization-of-the-efficacy-and-safety-of-antidepressant-therapy-in-patients-of-a-geriatric-psychiatric-unit
#1
COMPARATIVE STUDY
S I Gavrilova, Ya B Kalyn, T P Safarova, O B Yakovleva, V S Sheshenin, V V Kornilov, E S Shipilova
AIM: A comparative evaluation of the efficacy and safety of monotherapy with one of the modern antidepressants (venlafaxine, agomelatine, or fluvoxamine) and combination treatment of one of the above mentioned antidepressants with acetyl-L-carnitine (ALŠ”, carnicetine) in the geriatric psychiatric unit. MATERIAL AND METHODS: Two groups of elderly patients (aged 60-79 years) with mild or moderate depression, randomized according to a number of demographic and clinical characteristics, were treated with antidepressants in monotherapy or combined therapy (antidepressant/carnicetine) within 8 weeks...
2015: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/22027664/-acetyl-l-carnitine-carnicetine-in-the-treatment-of-early-stages-of-alzheimer-s-disease-and-vascular-dementia
#2
S I Gavrilova, Ia B Kalyn, I V Kolykhalov, I F Roshchina, N D Selezneva
Efficacy, safety and tolerability of acetyl-L-carnitine (ALC) were studied during the double-blind placebo-controlled 12-week trial in patients with mild (initial) dementia caused by the Alzheimer's disease (AD) and vascular dementia (VD). ALC was administered in doses from 2250 to 3000 mg per day. Patient's state was assessed with some scales (MMSE, CGI etc) and a battery of neuropsychological tests. The treatment effect of ALC was 2,8 times higher than in placebo-treated patients. The clinical improvement by CGI scores was significantly better in AD patients compared to VD and did not depend on the severity of baseline cognitive deficit...
2011: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
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