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https://www.readbyqxmd.com/read/29145504/quantifying-performance-on-an-outdoor-agility-drill-using-foot-mounted-inertial-measurement-units
#1
Antonia M Zaferiou, Lauro Ojeda, Stephen M Cain, Rachel V Vitali, Steven P Davidson, Leia Stirling, Noel C Perkins
Running agility is required for many sports and other physical tasks that demand rapid changes in body direction. Quantifying agility skill remains a challenge because measuring rapid changes of direction and quantifying agility skill from those measurements are difficult to do in ways that replicate real task/game play situations. The objectives of this study were to define and to measure agility performance for a (five-cone) agility drill used within a military obstacle course using data harvested from two foot-mounted inertial measurement units (IMUs)...
2017: PloS One
https://www.readbyqxmd.com/read/29145500/estimation-of-stress-distribution-in-ferromagnetic-tensile-specimens-using-low-cost-eddy-current-stress-measurement-system-and-bp-neural-network
#2
Jianwei Li, Weimin Zhang, Weiqin Zeng, Guolong Chen, Zhongchao Qiu, Xinyuan Cao, Xuanyi Gao
Estimation of the stress distribution in ferromagnetic components is very important for evaluating the working status of mechanical equipment and implementing preventive maintenance. Eddy current testing technology is a promising method in this field because of its advantages of safety, no need of coupling agent, etc. In order to reduce the cost of eddy current stress measurement system, and obtain the stress distribution in ferromagnetic materials without scanning, a low cost eddy current stress measurement system based on Archimedes spiral planar coil was established, and a method based on BP neural network to obtain the stress distribution using the stress of several discrete test points was proposed...
2017: PloS One
https://www.readbyqxmd.com/read/29145252/identifications-of-potential-therapeutic-targets-and-drugs-in-angiotensin-ii-induced-hypertension
#3
Xiaoli Wu, Ruihua Fan
This study aimed to identify the underlying therapeutic targets of angiotensin II (AngII)-induced hypertension, and screen the related drugs.The gene expression profiles of GSE93579 and GSE75815 were used to identify differentially expressed genes (DEGs) between AngII-induced hypertension and control samples based on meta-analysis. These DEGs were analyzed using Gene-Ontology (GO) function and pathway enrichment methods. Subsequently, the weighed gene coexpression network analysis (WGCNA)-based meta-analysis was applied to determine transcriptional signature with DEGs...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29144390/rna-sequencing-and-coexpression-analysis-reveal-key-genes-involved-in-%C3%AE-linolenic-acid-biosynthesis-in-perilla-frutescens-seed
#4
Tianyuan Zhang, Chi Song, Li Song, Zhiwei Shang, Sen Yang, Dong Zhang, Wei Sun, Qi Shen, Degang Zhao
Perillafrutescen is used as traditional food and medicine in East Asia. Its seeds contain high levels of α-linolenic acid (ALA), which is important for health, but is scarce in our daily meals. Previous reports on RNA-seq of perilla seed had identified fatty acid (FA) and triacylglycerol (TAG) synthesis genes, but the underlying mechanism of ALA biosynthesis and its regulation still need to be further explored. So we conducted Illumina RNA-sequencing in seven temporal developmental stages of perilla seeds...
November 16, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29143889/beyond-pathologizing-harm-understanding-ptsd-in-the-context-of-war-experience
#5
Patricia Benner, Jodi Halpern, Deborah R Gordon, Catherine Long Popell, Patricia W Kelley
An alternative to objectifying approaches to understanding Post-traumatic Stress Disorder (PTSD) grounded in hermeneutic phenomenology is presented. Nurses who provided care for soldiers injured in the Iraq and Afghanistan wars, and sixty-seven wounded male servicemen in the rehabilitation phase of their recovery were interviewed. PTSD is the one major psychiatric diagnosis where social causation is established, yet PTSD is predominantly viewed in terms of the usual neuro-physiological causal models with traumatic social events viewed as pathogens with dose related effects...
November 16, 2017: Journal of Medical Humanities
https://www.readbyqxmd.com/read/29143841/ionic-liquids-as-stationary-phases-for-fatty-acid-analysis-by-gas-chromatography
#6
REVIEW
C Fanali, G Micalizzi, P Dugo, L Mondello
The present paper provides an overview of the application of ionic liquid (IL) columns for GC analysis of fatty acid methyl esters (FAMEs). Although their separation can be carried out utilizing GC columns containing polar stationary phases, some ILs have been employed as stationary phases, either commercial or laboratory made, in GC analysis. Monodimensional and bidimensional GC methods have been optimized in order to achieve the best separation especially considering the geometric and positional isomers of unsaturated fatty acids...
November 16, 2017: Analyst
https://www.readbyqxmd.com/read/29143760/nano-aptasensing-in-mycotoxin-analysis-recent-updates-and-progress
#7
REVIEW
Amina Rhouati, Gonca Bulbul, Usman Latif, Akhtar Hayat, Zhan-Hong Li, Jean Louis Marty
Recent years have witnessed an overwhelming integration of nanomaterials in the fabrication of biosensors. Nanomaterials have been incorporated with the objective to achieve better analytical figures of merit in terms of limit of detection, linear range, assays stability, low production cost, etc. Nanomaterials can act as immobilization support, signal amplifier, mediator and artificial enzyme label in the construction of aptasensors. We aim in this work to review the recent progress in mycotoxin analysis. This review emphasizes on the function of the different nanomaterials in aptasensors architecture...
October 28, 2017: Toxins
https://www.readbyqxmd.com/read/29143570/the-perceptual-responses-to-high-velocity-low-load-and-low-velocity-high-load-resistance-exercise-in-older-adults
#8
Darren L Richardson, Michael J Duncan, Alfonso Jimenez, Victoria M Jones, Paul M Juris, Neil D Clarke
The present study examined exercise affect during volume-load matched, high-velocity, low-load and low-velocity, high-load resistance exercise conditions in older adults. Ten older adults completed three sets of eight exercises on six separate occasions (three high-velocity, low-load and three low-velocity, high-load sessions) in a crossover study design. High-velocity, low-load was performed at 40% of predicted one repetition maximum, and low-velocity, high-load at 80%. The Physical Activity Affect Scale, Felt Arousal Scale, Feeling Scale, Rating of Perceived Exertion, Visual Analogue Scales, and the Physical Activity Enjoyment Scale examined exercise intensity and affect...
November 16, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29143208/a-new-measure-for-end-of-life-planning-preparation-and-preferences-in-huntington-disease-hdqlife-end-of-life-planning
#9
Noelle E Carlozzi, E A Hahn, S A Frank, J S Perlmutter, N D Downing, M K McCormack, S Barton, M A Nance, S G Schilling
BACKGROUND: Huntington disease is a fatal inherited neurodegenerative disease. Because the end result of Huntington disease is death due to Huntington disease-related causes, there is a need for better understanding and caring for individuals at their end of life. AIM: The purpose of this study was to develop a new measure to evaluate end of life planning. DESIGN: We conducted qualitative focus groups, solicited expert input, and completed a literature review to develop a 16-item measure to evaluate important aspects of end of life planning for Huntington disease...
November 15, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/29142443/oral-health-and-erectile-dysfunction
#10
REVIEW
Vijendra P Singh, Sunil K Nettemu, Sowmya Nettem, Rajesh Hosadurga, Sangeeta U Nayak
Ample evidence strongly supports the fact that periodontal disease is a major risk factor for various systemic diseases namely cardio-vascular disease, diabetes mellitus, etc. Recently, investigators focussed on exploring the link between chronic periodontitis (CP) and erectile dysfunction (ED) by contributing to the endothelial dysfunction. Both the diseases share common risk factors. Various studies conducted in different parts of the world in recent years reported the evidence linking this relationship as well as improvement in ED with periodontal treatment...
July 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29142404/chalepin-a-compound-from-ruta-angustifolia-l-pers-exhibits-cell-cycle-arrest-at-s-phase-suppresses-nuclear-factor-kappa-b-nf-%C3%AE%C2%BAb-pathway-signal-transducer-and-activation-of-transcription-3-stat3-phosphorylation-and-extrinsic-apoptotic-pathway-in-non-small-cell
#11
Jaime Stella Moses Richardson, Norhaniza Aminudin, Sri Nurestri Abd Malek
Background: Plants have been a major source of inspiration in developing novel drug compounds in the treatment of various diseases that afflict human beings worldwide. Ruta angustifolia L. Pers known locally as Garuda has been conventionally used for various medicinal purposes such as in the treatment of cancer. Objective: A dihydrofuranocoumarin named chalepin, which was isolated from the chloroform extract of the plant, was tested on its ability to inhibit molecular pathways of human lung carcinoma (A549) cells...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29142346/conjugation-of-antibodies-with-radiogold-nanoparticles-as-an-effector-targeting-agents-in-radiobioconjugate-cancer-therapy-optimized-labeling-and-biodistribution-results
#12
Pankaj Garg, Daya Kishore Hazra
Purpose of the Study: Drug accessibility to the tumor cells is an important area of concern with an anticipation of increasing the efficacy of the drug to be delivered to a specific site. The biogenesis of gold nanoparticles using plant-mediated phytochemical extracts and their possible linkage to cancer antibodies with an aim at delivering the conjugate specifically to the tumor-associated antigen is the basic objective of the research. Materials and Methodology: Radiolabeling of antibodies with gold nanoparticles was carried out by a protocol, and the labeling extent of antibodies was compared with that of a radiogold solution to ordinary particulate size (AuNO-Ab)...
October 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/29142191/immune-neuroendocrine-interactions-evolution-ecology-and-susceptibility-to-illness
#13
Johanna M C Blom, Enzo Ottaviani
The integration between immune and neuroendocrine systems is crucial for maintaining homeostasis from invertebrates to humans. In the first, the phagocytic cell, i.e., the immunocyte, is the main actor, while in the latter, the principle player is the lymphocyte. Immunocytes are characterized by the presence of pro-opiomelanocortin (POMC) peptides, CRH, and other molecules that display a significant similarity to their mammalian counterparts regarding their functions, as both are mainly involved in fundamental functions such as immune (chemotaxis, phagocytosis, cytotoxicity, etc...
November 16, 2017: Medical Science Monitor Basic Research
https://www.readbyqxmd.com/read/29141979/measurement-errors-in-dietary-assessment-using-self-reported-24-hour-recalls-in-low-income-countries-and-strategies-for-their-prevention
#14
Rosalind S Gibson, U Ruth Charrondiere, Winnie Bell
Securing accurate measurements of dietary intake across populations is challenging. Of the methods, self-reported 24-h recalls are often used in low-income countries (LICs) because they are quick, culturally sensitive, do not require high cognitive ability, and provide quantitative data on both foods and nutrients. Measuring intakes via 24-h recalls involves 1) collecting data on food intakes, 2) the appropriate use of relevant food-composition data for calculating nutrient intakes, and 3) statistically converting observed intakes to "usual intakes" for evaluating nutrient adequacy or relations between foods and nutrients and health outcomes...
November 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/29141561/steroidal-anticancer-agents-an-overview-of-estradiol-related-compounds
#15
Renata Minorics, Istvan Zupko
Research of steroidal compounds as anticancer agents started almost 50 years ago. During the past decades several innovative new steroids, like cyproterone, finasteride, estramustin, exemestane and fulvestrant have successfully become part of routine clinical practice. Meanwhile, a vast amount of new information have accumulated about the functions of the endogenous steroid system (including the characterization of enzymes, receptors, transcription pathways, etc.) and about the role of steroids in carcinogenesis...
November 13, 2017: Anti-cancer Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/29141399/factors-affecting-cognitive-function-according-to-gender-of-in-community-dwelling-elderly
#16
Kim Miwon, Jeongmo Park
Objectives: This study aimed to identify the factors affecting the cognitive function of elderly people in a community by gender. Methods: 4,878 of secondary data of people aged ≥65 years in 2016 at a dementia prevention center in Geyangu in Incheon. Data were obtained through MMSE-DS and a questionnaire. The data were statistically analyzed using analysis of variance, analysis of covariance, and hierarchical regression. Results: There were significant differences in cognitive function according to sex, and the differences were significant even when age was controlled, but gender differences disappeared when education was controlled...
November 15, 2017: Epidemiology and Health
https://www.readbyqxmd.com/read/29141354/-research-progress-on-unprotected-anal-intercourse-and-its-influencing-factors-in-men-who-have-sex-with-men
#17
S Lu, D M Li
The prevalence of HIV infections continues to rise among Chinese MSM. This population is prone to has high-risk behaviors including having multiple sexual partners, unprotected anal intercourse (UAI), etc. This paper summarizes the situation of UAI and related influencing factors, including age, educational level, number of sexual partners, recreational drug abusing and related status of discrimination, etc. The purpose of this article is to provide reference for targeted intervention and prevention of HIV among MSM population...
November 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/29141330/-prenatal-supplementations-of-iron-iron-containing-multimicronutrients-and-antianemic-chinese-patent-medicines-in-women-in-shaanxi-province-2010-2013
#18
D M Liu, J M Li, P F Qu, S N Dang, X Y Wu, R Zhang, H Yan, H Yan
Objective: To understand the prevalence of prenatal supplementations of iron, iron-containing multi-micronutrients (IMMN) and antianemic Chinese patent medicines (ACPM) and associated factors in women in Shaanxi province. Methods: A sample of 28 367 childbearing-age women who gave birth during 2010-2013 and had specific information of the prenatal nutrients supplementation were recruited using stratified multistage cluster random sampling in Shaanxi province. The information about their basic characteristics and prenatal supplementation of nutrients were collected by a questionnaire survey...
November 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/29141305/-research-progress-on-rhinitis-medicamentosa
#19
Y N Wang, Z L Luan, H T Wang
Rhinitis medicamentosa (RM) refers to nonallergic inflammation in the nasal mucosa which is caused by the abuse of nasal decongestant and it often occurs in patients with allergic/nonallergic rhinitis along with nasal congestion. RM is characterized by nasal congestion based on long-term use of nasal decongestant, without rhinorrhoea or sneezing. The signs of RM include nasal swelling, thickening, loss of elasticity, and loss of sensitivity to the decongestant. The histological changes of RM are loss of nasal mucosa cilia, squamous epithelium metaplasia, edema of epithelium cell, hyperplasia of goblet cell, increased expression of epidermal growth factor receptor and infiltration of inflammatory cells, etc...
November 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29140605/highly-transparent-and-integrable-surface-texture-change-device-for-localized-tactile-feedback
#20
Ankit, Naveen Tiwari, Mayank Rajput, Nguyen Anh Chien, Nripan Mathews
Human-machine haptic interaction is typically detected by variations in friction, roughness, hardness, and temperature, which combines to create sensation of surface texture change. Most of the current technologies work to simulate changes in tactile perception (via electrostatic, lateral force fields, vibration motors, etc.) without creating actual topographical transformations. This makes it challenging to provide localized feedback. Here, a new concept for on-demand surface texture augmentation that is capable of physically forming local topographic features in any predesigned pattern is demonstrated...
November 15, 2017: Small
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