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Cancers, surgical oncology, surgical oncology

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https://www.readbyqxmd.com/read/29778621/-surgical-treatment-of-early-stage-non-small-cell-lung-cancer-by-thoracoscopic-segmental-resection
#1
A Seguin-Givelet, J Lutz, E Brian, M Grigoroiu, D Gossot
The rate of segmental resection for early stage non-small cell lung carcinoma (NSCLC) is increasing. However, the indications remain controversial. The aim of this study is to analyze the preliminary results of thoracoscopic segmental resection in early stage NSCLC in terms of morbidity, oncological validity and survival. We report the preliminary results of a consecutive series of 226 thoracoscopic segmentectomies for suspicion of early stage NSCLC. PATIENTS AND METHODS: Between 2007 and 2016, we performed 322 thoracoscopic anatomical sublobar resections (ASLR)...
May 17, 2018: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/29775735/robotic-versus-conventional-laparoscopic-gastrectomy-for-gastric-cancer-a-retrospective-cohort-study
#2
Hong-Bin Liu, Wen-Jie Wang, Hong-Tao Li, Xiao-Peng Han, Lin Su, Deng-Wen Wei, Ting-Bao Cao, Jian-Ping Yu, Zuo-Yi Jiao
BACKGROUND: Robot-assisted gastrectomy (RAG), as an alternative minimally invasive surgical technique, is gradually being used for the treatment of gastric cancer (GC). This study aimed to assess the feasibility and safety of RAG over conventional Laparoscopy-assisted gastrectomy (LAG) for the treatment of GC. METHODS: We retrospectively analyzed all procedures (RAG and LAG) performed by one surgeon between 31 January 2017 and 1 December 2017. The short-term of surgical outcomes were compared between two groups and further subgroup analyses were performed...
May 15, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29775552/right-colon-resection-for-colon-cancer-does-surgical-approach-matter
#3
Ivy N Haskins, Tammy Ju, Matthew Skancke, Xiangyu Kuang, Richard L Amdur, Fred Brody, Vincent Obias, Samir Agarwal
BACKGROUND: Surgical resection with curative intent remains the standard of care for colon cancer. This study aims to compare the 30-day outcomes and oncologic results following open, laparoscopic, and robot-assisted right colon resection for colon cancer using the Targeted Colectomy American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database. MATERIALS AND METHODS: All patients undergoing elective, right colon resection with primary anastomosis were identified within the targeted colectomy ACS-NSQIP database...
May 18, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29773761/surgical-treatment-of-pancreatic-cancer
#4
Wioletta Masiak-Segit, Karol Rawicz-Pruszyński, Magdalena Skórzewska, Wojciech P Polkowski
The only way to cure the patient with adenocarcinoma of the pancreas (RT) is surgical excision of the tumor. The standard surgical treatment of resectable pancreatic carcinoma is considered the classic pancreatoduodenectomy (PD) with the Kausch- Whipple procedure, or the pylorus-preserving PD with the Traverso-Longmire method. The most difficult technically and at the same time the most important PD stage from an oncological point of view is the separation of the head of the pancreas from the superior mesenteric artery...
April 30, 2018: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/29771723/comparing-short-term-and-oncologic-outcomes-of-minimally-invasive-versus-open-pancreaticoduodenectomy-across-low-and-high-volume-centers
#5
Robert J Torphy, Chloe Friedman, Alison Halpern, Brandon C Chapman, Steven S Ahrendt, Martin M McCarter, Barish H Edil, Richard D Schulick, Ana Gleisner
OBJECTIVE: To compare short-term and oncologic outcomes of patients with cancer who underwent open pancreaticoduodenectomy (OPD) versus minimally invasive pancreaticoduodenectomy (MIPD) using the National Cancer Database. SUMMARY BACKGROUND DATA: MIPD, including laparoscopic and robotic approaches, has continued to gain acceptance despite prior reports of increased short-term mortality when compared with OPD. METHODS: Patients with pancreatic cancer diagnosed from 2010 to 2015 undergoing curative intent resection were selected from the National Cancer Database...
May 16, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29770621/are-patients-and-physicians-willing-to-accept-less-radical-procedures-for-cervical-cancer
#6
Kemal Gungorduk, Roman Kocian, Derman Basaran, Taner Turan, Aykut Ozdemir, David Cibula
OBJECTIVE: To evaluate the opinions of women who underwent surgery for cervical cancer (CC) and physicians who treat CC about the acceptability of increased oncological risk after less-radical surgery. METHODS: One hundred eighty-two women who underwent surgery for CC and 101 physicians participated in a structured survey in 3 tertiary cancer centers in Czech Republic and Turkey. Patients and physicians were asked whether they would accept any additional oncological risks, which would be attributable to the omission of parametrectomy (radical hysterectomy/trachelectomy vs...
March 12, 2018: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29768067/the-development-of-fluorescence-guided-surgery-for-pancreatic-cancer-from-bench-to-clinic
#7
Thinzar M Lwin, Robert M Hoffman, Michael Bouvet
Surgeons face major challenges in achieving curative R0 resection for pancreatic cancers. When the lesion is localized, they must appropriately visualize the tumor, determine appropriate resection margins, and ensure complete tumor clearance. Real-time surgical navigation using fluorescence-guidance has enhanced the ability of surgeons to see the tumor and has the potential to assist in achieving more oncologically-complete resections. When there is metastatic disease, fluorescence enhancement can help detect these lesions and prevent unnecessary and futile surgeries...
May 16, 2018: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/29766779/technetium-99m-based-radiopharmaceuticals-in-sentinel-lymph-node-biopsy-gynecologic-oncology-perspective
#8
Kamil Zalewski, Malgorzata Benke, Bartlomiej Mirocha, Jakub Radziszewski, Magdalena Chechlinska, Magdalena Kowalewska
Technetium (99mTc)-radiolabeled colloids are popular tracers used to map lymphatic vessels and regional lymph nodes (LNs). The regional LN status is a significant determinant of cancer stage and patient prognosis, and strongly influences treatment. Regional LN dissection has become part of surgical treatment. However, not all patients with LN involvement benefit from extensive lymphadenectomy in terms of prolonged survival. Moreover, overtreatment of patients with localized disease carries unnecessary risk of complications...
May 15, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29766739/lingual-thyroid-carcinoma-a-case-report-and-review-of-surgical-approaches-in-the-literature
#9
William Stokes, Eric Interval, Rusha Patel
INTRODUCTION: Lingual thyroid cancer is a rare entity with a paucity of literature guiding methods of surgical treatment. Its location presents anatomic challenges with access and excision. OBJECTIVE: We present a case of T4aN1b classical variant papillary thyroid carcinoma of the lingual thyroid that was removed without pharyngeal entry. We also present a review of the literature of this rare entity and propose a treatment algorithm to provide safe and oncologic outcomes...
May 1, 2018: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29765794/femoral-access-for-central-venous-port-system-implantation
#10
Mikhail Cherkashin, Natalia Berezina, Denis Puchkov, Kirill Suprun, Petr Yablonsky
Totally implanted venous access port (TIVAP) systems provide adequate quality of care and life, especially for oncology patients. Long-term vascular access is very important and easy to perform, but in some clinical situations, if patients have a superior caval system occlusion, femoral insertion may be the only option. We present a case of a 70-year-old colorectal adenocarcinoma patient diagnosed with subclavian vein hypoplasia. Her care team decided intraoperatively to implant a port system by the right femoral access...
March 14, 2018: Curēus
https://www.readbyqxmd.com/read/29765545/multi-institution-analysis-of-racial-disparity-among-african-american-men-eligible-for-prostate-cancer-active-surveillance
#11
Michael Dinizo, Weichung Shih, Young Suk Kwon, Daniel Eun, Adam Reese, Laura Giusto, Edouard J Trabulsi, Bertram Yuh, Nora Ruel, Daniel Marchalik, Jonathan Hwang, Shilajit D Kundu, Scott Eggener, Isaac Yi Kim
There is a significant controversy on whether race should be a factor in considering active surveillance for low-risk prostate cancer. To address this question, we analyzed a multi-institution database to assess racial disparity between African-American and White-American men with low risk prostate cancer who were eligible for active surveillance but underwent radical prostatectomy. A retrospective analysis of prospectively collected clinical, pathologic and oncologic outcomes of men with low-risk prostate cancer from seven tertiary care institutions that underwent radical prostatectomy from 2003-2014 were used to assess potential racial disparity...
April 20, 2018: Oncotarget
https://www.readbyqxmd.com/read/29762198/endometrial-cancer-in-the-elderly-does-age-influence-surgical-treatments-outcomes-and-prognosis
#12
Meriem Koual, Charlotte Ngo, Aude Girault, Fabrice Lécuru, Anne-Sophie Bats
OBJECTIVE: To compare clinicopathological characteristics, surgical outcomes, and survival rates for nonelderly (<75 years old) and elderly (≥75 years old) women with endometrial cancer (EC). METHODS: This retrospective study included consecutive patients who underwent surgery for EC at the gynecologic-oncologic surgery department of Hôpital Européen Georges-Pompidou (Paris, France) from January, 2002 to December, 2015. Independent-group t tests and chi-square tests were used to compare elderly and nonelderly women...
May 14, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29761510/initiation-of-adjuvant-therapy-following-surgical-resection-of-pancreatic-ductal-adenocarcinoma-pdac-are-patients-from-rural-remote-areas-disadvantaged
#13
Kimberly A Bertens, John D Massman, Scott Helton, Samuel Garbus, Margaret M Mandelson, Bruce Lin, Vincent J Picozzi, Thomas Biehl, Adnan A Alseidi, Flavio G Rocha
BACKGROUND AND OBJECTIVES: Although race and socioeconomic status have been shown to affect outcomes in pancreatic ductal adenocarcinoma (PDAC), the impact of rural residence on the delivery of adjuvant therapy (AT) has not been studied. METHODS: Patients with resected PDAC were identified using the National Cancer Database (NCDB). Individuals were classified as living in a metro area, urban/rural adjacent to a metro area (URA), and urban/rural remote (URR) area...
May 14, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29756991/the-immune-landscape-of-non-small-cell-lung-cancer-utility-of-cytologic-and-histologic-samples-obtained-through-minimally-invasive-pulmonary-procedures
#14
Jason Beattie, Lonny Yarmus, Momen Wahidi, M Patricia Rivera, Christopher Gilbert, Fabien Maldonado, Kasia Czarnecka, Angela Argento, Alexander Chen, Felix Herth, Daniel H Sterman
The success of immune checkpoint inhibitors and the discovery of useful biomarkers to predict response to these agents has shifted much of the focus of personalized care for advanced non-small cell lung cancer towards harnessing the immune response. With further advancement, more effective immunotherapy options will emerge along with more useful biomarkers. For patients with advanced disease, minimally invasive techniques will remain most appropriate for acquisition of tissue. This is in contrast to default gold-standard large tissue specimens obtained through surgical resection...
May 14, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29756609/impact-of-resection-margin-status-on-oncological-outcomes-after-co2-laser-cordectomy
#15
P Aluffi Valletti, F Taranto, A Chiesa, F Pia, G Valente
The management of positive resection margins in micro-endoscopic glottic laser surgery remains a controversial and critical point. This study aims to assess the impact of margin status after transoral laser surgery on local control, survival and organ preservation rates; the decision-making process and treatment options in cases with positive margins are also discussed. We retrospectively reviewed the clinical and histological records of 308 consecutive patients with primary early glottic carcinoma (T1a, T1b, selected T2) and treated with endoscopic laser cordectomy...
February 2018: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29756367/oral-cancer-involving-masticator-space-t4b-review-of-literature-and-future-directions
#16
REVIEW
Nirav P Trivedi
The oral cancer with masticator-space involvement is classified as T4b disease. The limited data suggest that the masticator space is a complex anatomic area and tumors with varying degrees of infiltration may have different oncologic outcomes. It is not advisable to group all T4b tumors as one and consider them for palliative-intent treatment. A group of patients with limited spread (infra-notch) has potential for good outcome. These cancers can be considered for downstaging to T4a classification based on best available data and clinical considerations...
May 13, 2018: Head & Neck
https://www.readbyqxmd.com/read/29756123/the-quality-of-total-mesorectal-excision-specimen-a-review-of-its-macroscopic-assessment-and-prognostic-significance
#17
Shi-Bo Song, Guo-Ju Wu, Hong-Da Pan, Hua Yang, Mao-Lin Hu, Qiang Li, Qiu-Xia Yan, Gang Xiao
As a surgical procedure which could significantly lower the recurrence rate of cancers, total mesorectal excision (TME) has been the gold standard for middle and lower rectal cancer treatment. However, previous studies have shown that the procedure did not achieve the ideal theoretical local recurrence rates of rectal cancers. Some researchers pointed out it was very likely that not all so-called TME treatments completely removed the mesorectum, implying that some of these TME surgical treatments failed to meet oncological quality standards...
March 2018: Chronic Diseases and Translational Medicine
https://www.readbyqxmd.com/read/29750982/technical-feasibility-and-oncological-safety-of-diagnostic-endoscopic-resection-for-superficial-esophageal-cancer
#18
Masashi Takeuchi, Koichi Suda, Yasuo Hamamoto, Motohiko Kato, Shuhei Mayanagi, Kayo Yoshida, Kazumasa Fukuda, Rieko Nakamura, Norihito Wada, Hirofumi Kawakubo, Hiroya Takeuchi, Naohisa Yahagi, Yuko Kitagawa
BACKGROUND: Active use of endoscopic resection (ER) for cM3-SM2 esophageal cancer may enable sufficient extent of esophageal resection and help determine the need for lymph node dissection based on histopathological findings. However, ER preceding esophagectomy may have an adverse impact on outcomes. This study was designed to determine the technical feasibility and oncological safety of diagnostic ER. METHODS: A single-institution retrospective cohort study was performed between July 2008 and June 2014...
May 8, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29750392/laparoscopic-versus-robot-assisted-partial-nephrectomy-for-renal-tumors-larger-than-4-cm-a-propensity-score-based-analysis
#19
Liangyou Gu, Hongzhao Li, Baojun Wang, Yongpeng Xie, Xintao Li, Yu Gao, Xiangjun Lyu, Qingbo Huang, Yang Fan, Yuanxin Yao, Yunpeng Wang, Xin Ma, Xu Zhang
OBJECTIVES: To compare perioperative, functional, and oncological outcomes between laparoscopic partial nephrectomy (LPN) and robot-assisted partial nephrectomy (RAPN) for renal tumors >4 cm. MATERIAL AND METHODS: We retrospectively reviewed patients who underwent either LPN or RAPN between 2008 and 2015. To adjust for potential baseline confounders, propensity-score matching (1:1) was performed. Perioperative data, and functional and oncological outcomes were reviewed...
May 11, 2018: BJU International
https://www.readbyqxmd.com/read/29749774/bladder-cancer-overview-and-disease-management-part-1-non-muscle-invasive-bladder-cancer
#20
Beverley Anderson
Part 1 of this two-part article provides an overview of bladder cancer and discusses its management. Since publication of a previous article entitled 'Understanding the role of smoking in the aetiology of bladder cancer' ( Anderson, 2009 ), the author has received many requests for an update. This article provides an overview of bladder cancer and its current management practices, underlining the continued role of smoking as the predominant risk factor in the disease's development. The management of bladder cancer is governed by specific guidelines...
May 10, 2018: British Journal of Nursing: BJN
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