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https://www.readbyqxmd.com/read/29901939/correlation-and-concordance-between-the-primary-glomerular-filtration-mdrd-6-and-creatinine-clearance-by-the-conventional-method
#1
Apolonio Aveitua-Guerrero, Leonor Ballesteros-Angeles, María del Carmen López-Parra, Rosario Santos-Barajas
Background: The aim of the study was to determine the correlation and concordance between the primary glomerular filtration rate estimated by the MDRD-6 (Modification of Diet in Renal Disease, (mL/min/1.73 m2) equation and the creatinine clearance in 24-hour urine (DCr.mL/min) by conventional method. Methods: Retrospective, observational and comparative study. We studied 180 patients, were quantified in serum: creatinine (Cr), urea nitrogen (BUN) albumin (Alb) and, in urine for 24 hours: creatinine (Cr)...
March 2018: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29890099/evaluaci%C3%A3-n-de-ecuaciones-que-utilizan-cistatina-c-para-estimar-filtrado-glomerular-en-adultos-sanos-candidatos-a-donantes-renales
#2
Gisel Ivana Medina Arnaudo
Resumen: La valoración del Índice de Filtrado Glomerular (IFG) es fundamental para la selección de potenciales donantes renales. Para su medición existen métodos poco prácticos y complejos, por lo cual se han desarrollado ecuaciones de estimación del IFG. Objetivo: Evaluar el rendimiento diagnóstico de ecuaciones de estimación del IFG a partir de Creatinina y Cistatina C en una población de adultos sanos candidatos a donantes renales. Materiales y métodos: Se llevó a cabo un estudio transversal en 72 pacientes de ambos sexos de entre 18 y 75 años de edad, candidatos a donantes renales...
September 8, 2017: Revista de la Facultad de Ciencias Médicas
https://www.readbyqxmd.com/read/29871777/serum-metabolites-are-associated-with-all-cause-mortality-in-chronic-kidney-disease
#3
Jiun-Ruey Hu, Josef Coresh, Lesley A Inker, Andrew S Levey, Zihe Zheng, Casey M Rebholz, Adrienne Tin, Lawrence J Appel, Jingsha Chen, Mark J Sarnak, Morgan E Grams
Chronic kidney disease (CKD) involves significant metabolic abnormalities and has a high mortality rate. Because the levels of serum metabolites in patients with CKD might provide insight into subclinical disease states and risk for future mortality, we determined which serum metabolites reproducibly associate with mortality in CKD using a discovery and replication design. Metabolite levels were quantified via untargeted liquid chromatography and mass spectroscopy from serum samples of 299 patients with CKD in the Modification of Diet in Renal Disease (MDRD) study as a discovery cohort...
June 2, 2018: Kidney International
https://www.readbyqxmd.com/read/29862077/estimating-renal-function-in-the-elderly-malaysian-patients-attending-medical-outpatient-clinic-a-comparison-between-creatinine-based-and-cystatin-c-based-equations
#4
Maisarah Jalalonmuhali, Salma Mohamed Abouzriba Elagel, Maw Pin Tan, Soo Kun Lim, Kok Peng Ng
Background: To assess the performance of different GFR estimating equations, test the diagnostic value of serum cystatin-C, and compare the applicability of cystatin-C based equation with serum creatinine based equation for estimating GFR (eGFR) in comparison with measured GFR in the elderly Malaysian patients. Methods: A cross-sectional study recruiting volunteered patients 65 years and older attending medical outpatient clinic. 51 chromium EDTA (51 Cr-EDTA) was used as measured GFR...
2018: International Journal of Nephrology
https://www.readbyqxmd.com/read/29861638/prevalence-of-chronic-kidney-disease-in-nigeria-systematic-review-of-population-based-studies
#5
REVIEW
Innocent Ijezie Chukwuonye, Okechukwu Samuel Ogah, Ernest Ndukaife Anyabolu, Kenneth Arinze Ohagwu, Ogbonna Collins Nwabuko, Uwa Onwuchekwa, Miracle Erinma Chukwuonye, Emmanuel Chukwuebuka Obi, Efosa Oviasu
Background: The aim of this study was to identify and discuss published population-based studies carried out in Nigeria that have information on the prevalence of chronic kidney disease (CKD) and have also used the Kidney Disease Outcomes Quality Initiative (KDOQI) practice guidelines in defining CKD, with emphasis on the performance of three estimating equations for glomerular filtration rate (GFR) - Modification of Diet in Renal Disease (MDRD), Cock-croft-Gault, and CKD epidemiology collaboration (CKD-EPI) creatinine equation...
2018: International Journal of Nephrology and Renovascular Disease
https://www.readbyqxmd.com/read/29859046/burden-of-chronic-kidney-disease-on-the-african-continent-a-systematic-review-and-meta-analysis
#6
Arnaud D Kaze, Titilayo Ilori, Bernard G Jaar, Justin B Echouffo-Tcheugui
BACKGROUND: Accurate contemporary data on the burden of Chronic Kidney Disease (CKD) on the African continent are lacking. We determined the prevalence of CKD in adult populations living in Africa, and variations by stage, gender, estimated Glomerular Filtration Rate (eGFR) equation, and residence. METHODS: For this systematic review, we searched multiple electronic databases for original studies on CKD prevalence reported from January 1, 2000 to December 31, 2016...
June 1, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29848053/robotic-partial-nephrectomy-in-patients-with-chronic-kidney-disease-objective-measurement-of-short-and-long-term-renal-functional-outcomes
#7
Charbel Chalouhy, Jessica Moore Ruck, Tian Cheng Zhou, Abhishek Srivastava, Aryeh Keehn, Kara L Watts, Pedro Maria, Reza Ghavamian
BACKGROUND: Minimal literature informs the use of robotic partial nephrectomy (RPN) in patients with chronic kidney disease (CKD). Therefore, we evaluated the renal functional outcomes in CKD patients undergoing RPN. METHODS: We reviewed a prospective database of patients undergoing RPN 2010-2015 and identified 182 patients who had preoperative and postoperative nuclear renal scintigraphy (at 2 and 12 months postop). Pre-operative and 12-month post-operative eGFR (mL/min/1...
May 31, 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29791023/comparison-of-the-cockcroft-gault-mdrd-and-ckd-epi-equations-for-estimating-ganciclovir-clearance
#8
Maria-Eugenia Palacio-Lacambra, Immaculada Comas-Reixach, Albert Blanco-Grau, Josep-Maria Suñé-Negre, Alfonso Segarra-Medrano, José-Bruno Montoro-Ronsano
BACKGROUND: Accurately estimating kidney function is essential for the safe administration of renally cleared drugs like ganciclovir. Current practice recommends adjusting renally eliminated drugs according to the Cockcroft-Gault equation. There is no data on the utility of the Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations in ganciclovir dosing. PURPOSE: To evaluate which renal function equation best predicts ganciclovir clearance...
May 23, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29789986/optimal-equation-for-estimation-of-glomerular-filtration-rate-in-autosomal-dominant-polycystic-kidney-disease-influence-of-tolvaptan
#9
Tsuyoshi Yamaguchi, Eiji Higashihara, Takatsugu Okegawa, Isao Miyazaki, Kikuo Nutahara
BACKGROUND: The reliability of various equations for estimating the GFR in ADPKD patients and the influence of tolvaptan on the resulting estimates have not been examined when GFR is calculated on the basis of inulin clearance. METHODS: We obtained baseline and on-tolvaptan measured GFRs (mGFRs), calculated on the basis of inulin clearance, in 114 ADPKD, and these mGFRs were compared with eGFRs calculated according to four basic equations: the MDRD, CKD-EPI, and JSN-CKDI equations and the Cockcroft-Gault formula, as well as the influence of tolvaptan and of inclusion of cystatin C on accuracy of the results...
May 22, 2018: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/29779857/factors-affecting-the-incidence-of-contrast-induced-nephropathy-in-patients-undergoing-computed-tomography
#10
M Heras Benito, M Garrido Blázquez, Y Gómez Sanz, M Bernardez Mardomingo, J Ruiz Cacho, F J Rodríguez Recio, M J Fernández-Reyes Luis
OBJECTIVE: To analyze the incidence of contrast-induced nephropathy in a cohort of patients undergoing computed tomography (CT) with intravenous iodinated contrast material. To evaluate the efficacy of N-acetylcysteine in preventing contrast-induced nephropathy. PATIENTS AND METHODS: This prospective observational study was carried out in the months comprising March 2016 through July 2016. We selected the first five patients scheduled to undergo CT examination each day who agreed to participate and signed the informed consent form...
May 17, 2018: Radiología
https://www.readbyqxmd.com/read/29777021/serum-6-bromotryptophan-levels-identified-as-a-risk-factor-for-ckd-progression
#11
Adrienne Tin, Girish Nadkarni, Anne M Evans, Cheryl A Winkler, Erwin Bottinger, Casey M Rebholz, Mark J Sarnak, Lesley A Inker, Andrew S Levey, Michael S Lipkowitz, Lawrence J Appel, Dan E Arking, Josef Coresh, Morgan E Grams
Background Metabolite levels reflect physiologic homeostasis and may serve as biomarkers of disease progression. Identifying metabolites associated with APOL1 risk alleles-genetic variants associated with CKD risk commonly present in persons of African descent-may reveal novel markers of CKD progression relevant to other populations. Methods We evaluated associations between the number of APOL1 risk alleles and 760 serum metabolites identified via untargeted profiling in participants of the African American Study of Kidney Disease and Hypertension (AASK) ( n =588; Bonferroni significance threshold P <6...
May 18, 2018: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/29773235/factors-associated-with-renal-function-compensation-after-donor-nephrectomy
#12
Carla Burballa, Marta Crespo, Dolores Redondo-Pachón, María José Pérez-Sáez, Carlos Arias-Cabrales, Marisa Mir, Albert Francés, Lluís Fumadó, Lluís Cecchini, Julio Pascual
INTRODUCTION: Kidney transplant donors lose 50% of their renal mass after nephrectomy. The remaining kidney compensates for this loss and it is estimated that 70% of the baseline renal function prior to donation is recovered. Factors associated with post-donation renal compensation are not well understood. METHODS: Retrospective study of 66 consecutive kidney donors (mean age 48.8 years, 74.2% women). We analysed the potential factors associated with the compensatory mechanisms of the remaining kidney by comparing donors according to their renal compensation rate (RCR) (Group A, infra-compensation [<70%]; Group B, normal compensation [>70%])...
May 14, 2018: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/29768260/carboplatin-dosing-accuracy-by-estimation-of-glomerular-filtration-versus-creatinuria-in-cancer-patients
#13
Noiver Graciano Vera, Luis Pino Villarreal, Jenny Ureña Vargas
BACKGROUND: The glomerular filtration rate (GFR) is essential for calculating the dose and the monitoring of carboplatin. Although GFR measurement (mGFR) by external markers is ideal, in most cases these are not employed; the most used method is GFR estimation (eGFR) by formulae, hence the need to identify the formula with the best performance. METHODS: Patients admitted between 2011 and 2017 and diagnosed with ovarian, endometrial, lung, esophageal, or testicular cancer were assessed retrospectively...
May 16, 2018: Chemotherapy
https://www.readbyqxmd.com/read/29763910/different-relevance-of-peripheral-central-or-nighttime-blood-pressure-measurements-in-the-prediction-of-chronic-kidney-disease-progression-in-patients-with-mild-or-no-proteinuria
#14
Piotr Kuczera, Katarzyna Kwiecień, Marcin Adamczak, Teresa Bączkowska, Jolanta Gozdowska, Katarzyna Madziarska, Hanna Augustyniak-Bartosik, Marian Klinger, Magdalena Durlik, Eberhard Ritz, Andrzej Wiecek
BACKGROUND/AIMS: Arterial hypertension is one of the leading factors aggravating the course of chronic kidney disease (CKD). It seems that the novel parameters used in the assessment of the blood pressure (BP) load (i.e. central blood pressure, nighttime blood pressure) may be more precise in predicting the cardiovascular risk and the progression of CKD in comparison with the traditional peripheral blood pressure measurements in the office conditions. The aim of the study was to assess the impact of the central, or nighttime blood pressure on the progression of CKD in patients with mild or no-proteinuria (autosomal, dominant polycystic kidney disease or IgA nephropathy)...
May 10, 2018: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29738479/animal-and-plant-protein-intake-and-body-mass-index-and-waist-circumference-in-a-korean-elderly-population
#15
Ki-Byeong Park, Hyun Ah Park, Jae-Heon Kang, Kyoungwoo Kim, Young Gyu Cho, Jinyoung Jang
Controversy exists on whether animal and plant proteins influence obesity differently. The purpose of this study was to evaluate the association between total, animal, and plant protein intake with the body mass index (BMI), waist circumference (WC), and renal function in the Korean elderly. Study participants included Korean adults aged 60 years or older from the Korean National Health and Nutrition Examination Survey in 2013⁻2014. Height, weight, and waist circumference were measured and the body mass index was calculated...
May 8, 2018: Nutrients
https://www.readbyqxmd.com/read/29736630/variations-in-clinical-management-of-non-vitamin-k-antagonist-oral-anticoagulants-in-patients-with-atrial-fibrillation-according-to-different-equations-for-estimating-renal-function-post-hoc-analysis-of-a-prospective-cohort
#16
Vincenzo Livio Malavasi, Daniele Pettorelli, Elisa Fantecchi, Cristina Zoccali, Giuliana Laronga, Tommaso Trenti, Gregory Yoke Hong Lip, Giuseppe Boriani
Prescription of non-vitamin K antagonist oral anticoagulants (NOACs) requires an assessment of renal function (RF) and the Cockcroft-Gault (CG) equation is traditionally recommended. The objective of the study was to evaluate the potential changes in NOACs management using different equations for estimating RF. In a post hoc analysis of a prospective cohort of patients with atrial fibrillation, we considered different equations: (1) CG for creatinine clearance (CrCl), (2) modification of diet in renal disease (MDRD), (3) CKD-EPI, (4) Berlin Initiative Study 1 (BIS-1) and (5) full age spectrum (FAS), for glomerular filtration rate (GFR)...
May 7, 2018: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/29731924/the-spectrum-of-histopathological-changes-in-the-renal-allograft-a-12-months-protocol-biopsy-study
#17
Galina Severova-Andreevska, Ladislava Grcevska, Gordana Petrushevska, Koco Cakalaroski, Aleksandar Sikole, Olivera Stojceva-Taneva, Ilina Danilovska, Ninoslav Ivanovski
INTRODUCTION: Renal transplantation became a routine and successful medical treatment for Chronic Kidney Disease in the last 30 years all over the world. Introduction of Luminex based Single Antigen Beads (SAB) and recent BANFF consensus of histopathological phenotypes of different forms of rejection enables more precise diagnosis and changes the therapeutic approach. The graft biopsies, protocol or cause, indicated, remain a golden diagnostic tool for clinical follow up of kidney transplant recipients (KTR)...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29701319/serum-carbohydrate-antigen-153-and-renal-function-in-patients-with-type-2-diabetes-mellitus
#18
You-Fan Peng, Hao Lin, Man-Man Han, Ling Li
OBJECTIVE: The aim of our study was to investigate the correlation between serum carbohydrate antigen 153 (CA153) and renal function in patients with type 2 diabetes mellitus (T2DM). METHODS: A total of 184 patients with T2DM were included, and renal function was assessed by the modification of diet in renal disease (MDRD) formula adjusted coefficient of the Chinese people. RESULTS: Serum CA153 concentrations were positively correlated with blood glucose (BG) and glycated hemoglobin (HbA1c) (r = ...
April 27, 2018: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29685824/monitoring-of-patients-with-type-2-diabetes-and-nephropathy-in-a-specialized-diabetic-nephropathy-clinic-seems-to-be-beneficial
#19
N Vallianou, T Stratigou, A Paikopoulou, T Apostolou, B Vlassopoulou, S Tsagarakis, G Ioannidis
BACKGROUND: The purpose of this study was to evaluate the outcome of DM2 patients with nephropathy when they are under surveillance of a joined clinic run by endocrinologists & nephrologists. PATIENTS AND METHODS: A cohort of 106 patients with DM2, 42-83 years of age, and eGFR < 60 ml/min/m2 were included. Age, sex, duration of diabetes, duration of attending our clinic, smoking habits, BMI, data regarding ischemic heart disease and induction of hemodialysis, urine albumin excretion (UAE) levels, eGFR (MDRD equation) and values of various biochemical parameters were recorded too...
April 13, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29685332/estimated-glomerular-filtration-rate-is-an-early-biomarker-of-cardiac-surgery-associated-acute-kidney-injury
#20
Ángel Candela-Toha, María Carmen Pardo, Teresa Pérez, Alfonso Muriel, Javier Zamora
BACKGROUND: and objective Acute kidney injury (AKI) diagnosis is still based on serum creatinine and diuresis. However, increases in creatinine are typically delayed 48h or longer after injury. Our aim was to determine the utility of routine postoperative renal function blood tests, to predict AKI one or 2days in advance in a cohort of cardiac surgery patients. PATIENTS AND METHODS: Using a prospective database, we selected a sample of patients who had undergone major cardiac surgery between January 2002 and December 2013...
April 20, 2018: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
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