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https://www.readbyqxmd.com/read/28721320/detection-of-chronic-kidney-disease-by-using-different-equations-of-glomerular-filtration-rate-in-patients-with-type-2-diabetes-mellitus-a-cross-sectional-analysis
#1
Sojib Bin Zaman
Introduction Chronic kidney disease (CKD) is a global threat due to its high mortality. It is essential to know the actual magnitude of diabetic CKD to design a specific management program. However, there is limited knowledge regarding the most suitable equation to measure CKD in patients with Type 2 diabetes mellitus (T2DM). This paper aimed to analyze estimated glomerular filtration rate (eGFR) based on different equations to detect the CKD among T2DM.  Methods A hospital-based cross-sectional study was carried out, and a clinical registry was used to collect 4,042 T2DM patients from a large district hospital in Northeast Thailand...
June 14, 2017: Curēus
https://www.readbyqxmd.com/read/28712998/brain-natriuretic-peptide-mediates-the-prognostic-role-of-renal-function-towards-10-year-cardiovascular-mortality-in-patients-with-acute-coronary-syndrome-the-hhf-study-2006-2016
#2
Christina Chrysohoou, George Georgiopoulos, Hara Kosyfa, Ioanna Kotsopoulou Haritou, Matina Kouvari, Androniki Filippou, Stelios Iosifidis, Eleftherios Tsiamis, Panagiotis Aggelopoulos, Christos Pitsavos, Dimitris Tousoulis
BACKGROUND/INTRODUCTION: Risk stratification in chronic heart failure (HF) remains a challenge. Renal function and B-natriuretic peptide (BNP) might confer predictive value towards long-term mortality in HF patients after an acute coronary syndrome (ACS). METHODS: From May 2006 to March 2009, 1,000 consecutive patients who were hospitalized with ACS diagnosis were enrolled in the study. In 2016, the 10-year follow-up (2006-2016) was performed in 745 participants...
July 13, 2017: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/28711195/comparison-of-mdrd-ckd-epi-and-cockcroft-gault-equation-in-relation-to-measured-glomerular-filtration-rate-among-a-large-cohort-with-diabetes
#3
Anke Schwandt, Michael Denkinger, Peter Fasching, Martin Pfeifer, Christian Wagner, Jörg Weiland, Andrej Zeyfang, Reinhard W Holl
AIMS: To analyze the performance of Modification of Diet in Renal Disease (MDRD), Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), Cockcroft-Gault (CG), and CG calculated with ideal bodyweight (CG-IBW) equations to estimate glomerular filtration rate (eGFR) based on serum creatinine in a large diabetic population. METHODS: 24,516 adults with type-1-diabetes or type-2-diabetes from the multicenter diabetes prospective follow-up registry DPV were analyzed...
July 5, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28702264/comparative-performance-of-creatinine-based-estimated-glomerular-filtration-rate-equations-in-the-malays-a-pilot-study-in-tertiary-hospital-in-malaysia
#4
Maisarah Jalalonmuhali, Ng Kok Peng, Lim Soo Kun
AIM: To validate the accuracy of estimated glomerular filtration rate (eGFR) equations in Malay population attending our hospital in comparison with radiolabeled measured GFR. METHODS: A cross-sectional study recruiting volunteered patients in the outpatient setting. Chromium EDTA (51Cr-EDTA) was used as measured GFR. The predictive capabilities of Cockcroft-Gault equation corrected for body surface area (CGBSA), four-variable Modification of Diet in Renal Disease (4-MDRD), and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations were calculated...
2017: International Journal of Nephrology
https://www.readbyqxmd.com/read/28694691/assessment-of-renal-function-in-geriatric-palliative-care-patients-comparison-of-creatinine-based-estimation-equations
#5
Ewa Deskur-Smielecka, Aleksandra Kotlinska-Lemieszek, Jerzy Chudek, Katarzyna Wieczorowska-Tobis
BACKGROUND: Renal function impairment is common in geriatric palliative care patients. Accurate assessment of renal function is necessary for appropriate drug dosage. Several equations are used to estimate kidney function. AIMS: 1) To investigate the differences (Δ) in kidney function assessed with simplified Modifi-cation of Diet in Renal Disease (MDRD), Berlin Initiative Study (BIS1), and Cockcroft-Gault (C-G) formulas in geriatric palliative care patients, and 2) to assess factors that may influence these differences...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28693441/ckd-epi-creatinine-cystatin-c-glomerular-filtration-rate-estimation-equation-seems-more-suitable-for-chinese-patients-with-chronic-kidney-disease-than-other-equations
#6
Xiao-Hua Chi, Gui-Ping Li, Quan-Shi Wang, Yong-Shuai Qi, Kai Huang, Qian Zhang, Yao-Ming Xue
BACKGROUND: The aim of this study was to identify the optimal equation that accurately estimates the glomerular filtration rate (GFR) and the chronic kidney disease (CKD) stage in the Chinese population. METHODS: A total of 1296 Chinese patients aged 18-65 years old were enrolled in this study. The estimated GFRs (eGFRs) calculated separately by three Diet in Renal Disease (MDRD) equations and three Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations were compared with the reference GFR (rGFR) measured by the (99)Tc(m)-DTPA renal dynamic imaging method...
July 10, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28680358/interpretation-of-erythropoietin-and-haemoglobin-levels-in-patients-with-various-stages-of-chronic-kidney-disease
#7
Mirsad Panjeta, Ismet Tahirović, Emin Sofić, Jozo Ćorić, Amela Dervišević
BACKGROUND: The production of erythrocytes is regulated by the hormone erythropoietin (EPO), which maintains the blood haemoglobin (Hb) levels constant under normal conditions. Human EPO is a glycoprotein hormone and its synthesis is controlled by the hypoxia-inducible transcription factor. The aim of this study was to establish EPO and Hb levels in patients with chronic kidney disease (CKD), as well as in control subjects, and to investigate the relationship between these parameters...
April 2017: Journal of Medical Biochemistry
https://www.readbyqxmd.com/read/28680350/evaluation-of-renal-function-in-alzheimer-s-disease-and-geriatric-patients-results-from-a-turkish-two-center-study
#8
Zubeyde Erbayraktar, Ahmet Turan Evlice, Gokhan Yilmaz, Canan Yazici, Gorsev Yener, Nuriye Nuray Ulusu
BACKGROUND: Alzheimer's disease (AD) is a severe multifactorial neurodegenerative proteopathy associated with advanced age. Discrepancies in the renal function of these patients compared to geriatric patients with dementia have rarely been reported. In this study, we aimed to disclose the importance of associated renal changes for the pathogenesis of AD. METHODS: Patients with AD (n=107) and geriatric patients with dementia and without dementia (n=124) (231 patients in total) from Dokuz Eylul and Cukurova University Hospitals were enrolled in the study...
January 2017: Journal of Medical Biochemistry
https://www.readbyqxmd.com/read/28680201/comparison-between-two-sample-method-with-99m-tc-diethylenetriaminepentaacetic-acid-gates-method-and-estimated-glomerular-filtration-rate-values-by-formula-based-methods-in-healthy-kidney-donor-population
#9
Manish Kumar, Geetanjali Arora, Nishikant Avinash Damle, Praveen Kumar, Madhavi Tripathi, Chandrasekhar Bal, Sameer Kamlakar Taywade, Abhinav Singhal
PURPOSE OF THE STUDY: Glomerular filtration rate (GFR) is the most important parameter for the assessment of renal function. GFR by plasma sampling technique is considered accurate in the selection of donors for renal transplantation. Estimated GFR (eGFR) calculations using Gates' method and Modification of Diet in Renal Disease (MDRD) and Cockcroft-Gault (CG) equations are simple methods but have not been validated in the Indian population. Hence, we aimed to assess the correlation between these three techniques...
July 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28678812/augmented-renal-clearance-is-not-a-risk-factor-for-mortality-in-enterobacteriaceae-bloodstream-infections-treated-with-appropriate-empiric-antimicrobials
#10
Jason P Burnham, Scott T Micek, Marin H Kollef
The main objective of the study was to assess whether augmented renal clearance was a risk factor for mortality in a cohort of patients with Enterobacteriaceae sepsis, severe sepsis, or septic shock that all received appropriate antimicrobial therapy within 12 hours. Using a retrospective cohort from Barnes-Jewish Hospital, a 1,250-bed teaching hospital, we collected data on individuals with Enterobacteriaceae sepsis, severe sepsis, and septic shock who received appropriate initial antimicrobial therapy between June 2009 and December 2013...
2017: PloS One
https://www.readbyqxmd.com/read/28676189/changes-in-renal-function-after-discontinuation-of-vitamin-d-analogues-in-advanced-chronic-kidney-disease
#11
Francisco Caravaca, Fernando Caravaca-Fontán, Lilia Azevedo, Enrique Luna
BACKGROUND: In routine clinical practice, the prescription of vitamin D analogues (VDA) in patients with chronic kidney disease (CKD) is often associated with a decline of the estimated renal function. The reason for this is not fully understood. AIMS: To analyse the effects of VDA discontinuation in advanced CKD and to determine the factors associated with changes in renal function. MATERIAL AND METHODS: Retrospective cohort study of adult patients with advanced CKD...
July 1, 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/28662505/empirically-reduced-dosages-of-tinzaparin-in-patients-with-moderate-to-severe-renal-insufficiency-lead-to-inadequate-anti-xa-levels
#12
Renske H Olie, Nathalie E L Meertens, Yvonne M C Henskens, Hugo Ten Cate
BACKGROUND: Due to the higher molecular weight of tinzaparin, the low molecular weight heparin (LMWH) is less dependent on renal excretion than other LMWH preparations. However, several international guidelines recommend the same preemptive dosage reduction for all therapeutic dose LMWHs prescribed in renal insufficient patients, to ensure that there is no accumulation of anticoagulant activity and increased risk of bleeding. This study is aimed at assessing whether a preemptive dosage reduction of tinzaparin in all renal insufficient patients (comprising 25% reduction in patients with Modification of Diet in Renal Disease - estimated glomerular filtration rate (MDRD-eGFR) 30-60 mL/min/1...
June 30, 2017: Nephron
https://www.readbyqxmd.com/read/28658750/retrospective-comparison-of-estimated-gfr-using-2006-mdrd-2009-ckd-epi-and-cockcroft-gault-with-24-hour-urine-creatinine-clearance
#13
B Vinodh Kumar, Thuthi Mohan
INTRODUCTION: The assessment of Glomerular Filtration Rate (GFR) is essential for clinical practice in assessing kidney function, drug dosing, detecting and estimating the prognosis of Chronic Kidney Disease (CKD). The most common practical method for assessing GFR is performed with a 24 hour/timed urine collection for creatinine clearance evaluation. The estimation of eGFR by creatinine based formulae is known to be a rapid and reliable means of approximation of creatinine clearance...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28655389/role-of-dry-lean-body-mass-for-estimation-of-glomerular-filtration-rate-in-kidney-transplant-recipients
#14
Špela Borštnar, Jelka Lindič, Andrej Škoberne, Luka Ležaič, Aljaž Sočan, Aljoša Kandus, Damjan Kovač
BACKGROUND: The use of equations that predict glomerular filtration rate (GFR) in patients with a kidney graft is still a matter of debate. The purpose of this study was to determine the level of accuracy of GFR equations and the relevance of dry lean body mass in the assessment of GFR. METHODS: In a prospective clinical study, 100 patients with a kidney graft were included. Estimated GFR with Modification of Diet in Renal Disease equation (MDRD), Chronic Kidney Disease Epidemiology Collaboration equation (CKD EPI) with serum creatinine concentration (CKD EPI Cr), serum cystatin C concentration (CKD EPI CysC) or both (CKD EPI Cr-CysC), and creatinine clearance calculated with Cockcroft-Gault equation (CG) was compared with GFR measured by 51Cr-EDTA clearance (mGFR 51Cr-EDTA)...
June 28, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28648303/risk-of-esrd-and-mortality-associated-with-change-in-filtration-markers
#15
Casey M Rebholz, Lesley A Inker, Yuan Chen, Menglu Liang, Meredith C Foster, John H Eckfeldt, Paul L Kimmel, Ramachandran S Vasan, Harold I Feldman, Mark J Sarnak, Chi-Yuan Hsu, Andrew S Levey, Josef Coresh
BACKGROUND: Using change in estimated glomerular filtration rate (eGFR) based on creatinine concentration as a surrogate outcome in clinical trials of chronic kidney disease has been proposed. Risk for end-stage renal disease (ESRD) and all-cause mortality associated with change in concentrations of other filtration markers has not been studied in chronic kidney disease populations. STUDY DESIGN: Observational analysis of 2 clinical trials. SETTING & PARTICIPANTS: Participants in the MDRD (Modification of Diet in Renal Disease; n=317) Study and AASK (African American Study of Kidney Disease and Hypertension; n=373)...
June 22, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28645109/elevated-hemoglobin-glycation-index-identify-non-diabetic-individuals-at-increased-risk-of-kidney-dysfunction
#16
Teresa Vanessa Fiorentino, Maria Adelaide Marini, Elena Succurro, Angela Sciacqua, Francesco Andreozzi, Francesco Perticone, Giorgio Sesti
Hemoglobin glycation index (HGI), calculated as the difference between the observed value of HbA1 and the predicted HbA1c based on plasma glucose concentration, is a measure of the individual tendency toward non-enzymatic hemoglobin glycation which has been found to be positively associated with nephropathy in subjects with diabetes. In this cross-sectional study we aimed to evaluate whether higher HGI levels are associated with impaired kidney function also among nondiabetic individuals.The study group comprised 1505 White nondiabetic individuals stratified in quartiles according to HGI levels...
June 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/28643487/proenkephalin-neutrophil-gelatinase-associated-lipocalin-and-estimated-glomerular-filtration-rates-in-patients-with-sepsis
#17
Hanah Kim, Mina Hur, Seungho Lee, Rossella Marino, Laura Magrini, Patrizia Cardelli, Joachim Struck, Andreas Bergmann, Oliver Hartmann, Salvatore Di Somma
BACKGROUND: Proenkephalin (PENK) has been suggested as a novel biomarker for kidney function. We investigated the diagnostic and prognostic utility of plasma PENK in comparison with neutrophil gelatinase-associated lipocalin (NGAL) and estimated glomerular filtration rates (eGFR) in septic patients. METHODS: A total of 167 septic patients were enrolled: 99 with sepsis, 37 with septic shock, and 31 with suspected sepsis. PENK and NGAL concentrations were measured and GFR was estimated by using the isotope dilution mass spectrometry traceable-Modification of Diet in Renal Disease (MDRD) Study and three Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations: CKD-EPI(Cr), CDK-EPI(CysC), and CKD-EPI(Cr-CysC)...
September 2017: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/28587950/anemia-considerations-when-assessing-natriuretic-peptide-levels-in-ed-patients
#18
Inanc Karakoyun, Ayfer Colak, Fatma Demet Arslan, Aybike Gunaslan Hasturk, Can Duman
INTRODUCTION: The incidence of heart failure (HF) has reached epidemic levels in western populations, and the majority of these patients are admitted to hospitals through the emergency department (ED). We aimed to aid clinicians assessing natriuretic peptide (NP) levels in cases with suspected HF. In this study, we investigated the effect of anemia on amino-terminal pro-BNP (NT-proBNP) and on B-type natriuretic peptide (BNP) levels. METHODS: This retrospective study examined patients who were admitted to the ED with suspected HF...
May 31, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28583572/effect-of-donor-recipient-age-match-in-expanded-criteria-deceased-donor-kidney-transplantation
#19
K Ko, Y H Kim, M H Kim, K W Jun, J K Hwang, S D Kim, S C Park, J I Kim, I S Moon
PURPOSE: Our objective was to investigate the effects of age on patient and graft survival in expanded criteria donor (ECD) renal transplantation. METHODS: Between February 2000 and December 2015, we analyzed 405 deceased donor renal transplants, including 128 grafts (31.9%) from ECDs. Based on recipient age and ECD criteria classification, the recipients were divided into four groups: Group I, non-ECD to recipient age <50 years; Group II, non-ECD to recipient age ≥50 years; Group III, ECD to recipient age <50 years; and Group IV, ECD to recipient age ≥50 years...
June 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28583519/usefulness-of-multi-detector-computed-tomography-scanning-as-a-replacement-for-diethylenetriamine-pentaacetic-acid
#20
H H Lee, W K Han, S K Kang, K H Huh, M S Kim, S I Kim, Y S Kim, Y E Yoon
BACKGROUND: Diethylenetriamine pentaacetic acid (DTPA) and multi-detector computed tomography (MDCT) can predict postoperative estimated glomerular filtration rate (eGFR) in a live kidney donor. Accordingly, we compared predicted eGFR measured by use of DTPA and MDCT. METHODS: From January 2013 to May 2015, 264 live kidney donors were enrolled. All donors underwent preoperative DTPA and MDCT, and bilateral renal cortex volume was measured by use of MDCT. We estimated DTPA-eGFR [remaining split renal function (%) × preoperative eGFR] and Vol-eGFR [remaining renal volume/total renal volume (%) × preoperative eGFR] and analyzed DTPA-eGFR, Vol-eGFR, and Modification of Diet in Renal Disease (MDRD)-eGFR during week 1 and in months 1, 3, and 6...
June 2017: Transplantation Proceedings
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