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https://www.readbyqxmd.com/read/29332148/occurrence-of-pharmaceuticals-and-personal-care-products-and-their-associated-environmental-risks-in-a-large-shallow-lake-in-north-china
#1
Panwei Zhang, Huaidong Zhou, Kun Li, Xiaohui Zhao, Qiaona Liu, Dongjiao Li, Gaofeng Zhao
Eighteen selected pharmaceuticals and personal care products (PPCPs), consisting of five non-antibiotic pharmaceuticals (N-APs), four sulfonamides (SAs), four tetracyclines (TCs), four macrolides (MCs), and one quinolone (QN) were detected in water, pore water, and sediment samples from Baiyangdian Lake, China. A total of 31 water samples and 29 sediment samples were collected in March 2017. Caffeine was detected with 100% frequency in surface water, pore water, and sediment samples. Carbamazepine was detected with 100% frequency in surface water and sediment samples...
January 13, 2018: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/29331560/the-effects-of-sediment-transport-on-temporal-variation-in-radiocesium-concentrations-in-very-shallow-water-off-the-southern-coast-of-fukushima-japan
#2
Akira Matsumoto, Hiroshi Myouse, Hisayuki Arakawa, Ken Higuchi, Naoto Hirakawa, Yoshiaki Morioka, Takuji Mizuno
We studied the very shallow coastal water off Iwaki City, Fukushima Prefecture, and investigated: (1) temporal variation in 137Cs concentrations; (2) particle-size distribution of sediments; and (3) the effect on variation by waves, component-fractionated concentration of radiocesium and mineral composition at three sampling stations (Yotsukura, Ena rocky reef and Ena sandy station). There was a decline in 137Cs concentrations in sediment samples at all sampling stations between 425 and 1173 days after the accident...
January 11, 2018: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29329295/novel-signature-fatty-acid-profile-of-the-giant-manta-ray-suggests-reliance-on-an-uncharacterised-mesopelagic-food-source-low-in-polyunsaturated-fatty-acids
#3
Katherine B Burgess, Michel Guerrero, Andrea D Marshall, Anthony J Richardson, Mike B Bennett, Lydie I E Couturier
Traditionally, large planktivorous elasmobranchs have been thought to predominantly feed on surface zooplankton during daytime hours. However, the recent application of molecular methods to examine long-term assimilated diets, has revealed that these species likely gain the majority from deeper or demersal sources. Signature fatty acid analysis (FA) of muscle tissue was used to examine the assimilated diet of the giant manta ray Mobula birostris, and then compared with surface zooplankton that was collected during feeding and non-feeding events at two aggregation sites off mainland Ecuador...
2018: PloS One
https://www.readbyqxmd.com/read/29329140/slit-lamp-needling-of-the-anterior-capsule-for-aqeuous-misdirection-post-hyaloido-zonulectomy-and-iridectomy
#4
Pierre G Mardelli, Marc E Mardelli
INTRODUCTION: We present a case of persistent aqueous misdirection post Ahmed glaucoma valve despite undergoing an anterior vitrectomy with hyaloido-zonulectomy, and iridectomy. CASE REPORT: A 73 year old female 4 months post phaco-trabeculectomy was referred with persistent high IOP. Post-operatively, she developed aqueous misdirection with a flat anterior chamber (AC) but with an IOP of 15▒mm Hg. On presentation her AC was shallow with peripheral iris-cornea touch and IOP was 39▒mm Hg...
January 11, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29328958/stdp-based-spiking-deep-convolutional-neural-networks-for-object-recognition
#5
Saeed Reza Kheradpisheh, Mohammad Ganjtabesh, Simon J Thorpe, Timothée Masquelier
Previous studies have shown that spike-timing-dependent plasticity (STDP) can be used in spiking neural networks (SNN) to extract visual features of low or intermediate complexity in an unsupervised manner. These studies, however, used relatively shallow architectures, and only one layer was trainable. Another line of research has demonstrated - using rate-based neural networks trained with back-propagation - that having many layers increases the recognition robustness, an approach known as deep learning. We thus designed a deep SNN, comprising several convolutional (trainable with STDP) and pooling layers...
December 23, 2017: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/29328649/phenylthiomethyl-ketone-based-fragments-show-selective-and-irreversible-inhibition-of-enteroviral-3c-proteases
#6
Robert Schulz, Amira Atef, Daniel Becker, Franziska Gottschalk, Carolin Tauber, Stefan Wagner, Christoph Arkona, Atef A Abdel-Hafez, Hassan H Farag, Jörg Rademann, Gerhard Wolber
Lead structure discovery mainly focuses on the identification of noncovalently binding ligands. Covalent linkage, however, is an essential binding mechanism for a multitude of successfully marketed drugs although discovered by serendipity in most cases. We present a concept for the design of fragments covalently binding to proteases. Covalent linkage enables fragment binding unrelated to affinity to shallow protein binding sites and at the same time allows differentiated targeted hit verification and binding location verification through mass spectrometry...
January 12, 2018: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29328210/nonlinear-absorption-and-temperature-dependent-fluorescence-of-perovskite-fapbbr3-nanocrystal
#7
Lan Yang, Ke Wei, Zhongjie Xu, Feiming Li, Runze Chen, Xin Zheng, Xiangai Cheng, Tian Jiang
Recent progress in solar cell and light-emitting devices makes halide perovskite a research hot spot in optics. In this Letter, the nonlinear absorption and fluorescence properties of FAPbBr3 nanocrystal, one typical organometallic halide perovskite, have been investigated via Z-scan measurements and a density-dependent photoluminescence (PL) spectrum. The FAPbBr3 nanocrystal exhibits nonlinear absorption under the excitation of 800 nm, whose photon energy is below the bandgap of FAPbBr3. The significant absorption is experimentally confirmed to be induced by two-photon absorption (TPA), and the TPA coefficient is measured to be ∼0...
January 1, 2018: Optics Letters
https://www.readbyqxmd.com/read/29327637/evidence-of-shallow-mitochondrial-divergence-in-the-slender-armorhead-pentaceros-wheeleri-pisces-pentacerotidae-from-the-emperor-seamount-chain
#8
Seung Eun Bae, Hanna Kim, Seok-Gwan Choi, Jin-Koo Kim
Competitive overexploitation of the slender armorhead, Pentaceros wheeleri, a deep-sea fish inhabiting the Emperor Seamount Chain caused a serious population decline. Therefore, it is urgently necessary to clarify its genetic diversity and connectivity among populations of P. wheeleri for appropriate stock management. For this, we compared 677 base pairs (bp) of mitochondrial (mt) DNA control region (CR) sequences of 80 individuals from three seamounts (the Milwaukee, Kinmei, and Koko Seamounts) in the southern part of the Emperor Seamount Chain...
January 12, 2018: Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis
https://www.readbyqxmd.com/read/29326269/exposed-subsurface-ice-sheets-in-the-martian-mid-latitudes
#9
Colin M Dundas, Ali M Bramson, Lujendra Ojha, James J Wray, Michael T Mellon, Shane Byrne, Alfred S McEwen, Nathaniel E Putzig, Donna Viola, Sarah Sutton, Erin Clark, John W Holt
Thick deposits cover broad regions of the Martian mid-latitudes with a smooth mantle; erosion in these regions creates scarps that expose the internal structure of the mantle. We investigated eight of these locations and found that they expose deposits of water ice that can be >100 meters thick, extending downward from depths as shallow as 1 to 2 meters below the surface. The scarps are actively retreating because of sublimation of the exposed water ice. The ice deposits likely originated as snowfall during Mars' high-obliquity periods and have now compacted into massive, fractured, and layered ice...
January 12, 2018: Science
https://www.readbyqxmd.com/read/29325953/physical-risk-factors-of-hemorrhagic-complications-associated-with-angio-seal-closure-device-use-in-neurointerventional-procedures
#10
Yasuhiro Aida, Kouichi Misaki, Tomoya Kamide, Masanao Mohri, Naoyuki Uchiyama, Mitsutoshi Nakada
BACKGROUND: Few studies have demonstrated detailed physical risk factors of hemorrhagic complications (HC) associated with the Angio-Seal closure device. This retrospective study aimed to identify the risk factors of HC due to Angio-Seal use. METHODS: Data from 143 cases that underwent neurointerventional procedures that involved puncturing the femoral artery and that used an Angio-Seal to close the puncture site were reviewed. We divided these cases into HC and no HC groups and retrospectively compared age, sex, past medical and preference history, body mass index (BMI), femoral artery depth, dual antiplatelet therapy use, activated clotting time, general anesthesia use, sheath size, right femoral artery puncture, and treatment time...
January 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29324887/the-tracked-roaming-transect-and-distance-sampling-methods-increase-the-efficiency-of-underwater-visual-censuses
#11
Alejo J Irigoyen, Irene Rojo, Antonio Calò, Gastón Trobbiani, Noela Sánchez-Carnero, José A García-Charton
Underwater visual census (UVC) is the most common approach for estimating diversity, abundance and size of reef fishes in shallow and clear waters. Abundance estimation through UVC is particularly problematic in species occurring at low densities and/or highly aggregated because of their high variability at both spatial and temporal scales. The statistical power of experiments involving UVC techniques may be increased by augmenting the number of replicates or the area surveyed. In this work we present and test the efficiency of an UVC method based on diver towed GPS, the Tracked Roaming Transect (TRT), designed to maximize transect length (and thus the surveyed area) with respect to diving time invested in monitoring, as compared to Conventional Strip Transects (CST)...
2018: PloS One
https://www.readbyqxmd.com/read/29324791/sediment-biomarkers-elucidate-the-holocene-ontogeny-of-a-shallow-lake
#12
T E Arnold, W F Kenney, J H Curtis, T S Bianchi, M Brenner
We carried out geochemical analyses on a sediment core from Lake Harris, Florida (USA) to identify sources of organic matter to the sediment throughout the Holocene, and relate changes in those sources to shifts in past climate and environmental conditions. We hypothesized that the sources of organic matter changed in response to regional hydrologic shifts following de-glaciation, and to human population expansion in the state during the 20th century. Hydroclimate shifts in Florida were related to: 1) a steady rise in relative sea level and the fresh water table that began in the early Holocene, 2) wetland formation and expansion ca...
2018: PloS One
https://www.readbyqxmd.com/read/29321883/quantifying-the-effects-of-ecological-constraints-on-trait-expression-using-novel-trait-gradient-analysis-parameters
#13
Gianluigi Ottaviani, James L Tsakalos, Gunnar Keppel, Ladislav Mucina
Complex processes related to biotic and abiotic forces can impose limitations to assembly and composition of plant communities. Quantifying the effects of these constraints on plant functional traits across environmental gradients, and among communities, remains challenging. We define ecological constraint (Ci ) as the combined, limiting effect of biotic interactions and environmental filtering on trait expression (i.e., the mean value and range of functional traits). Here, we propose a set of novel parameters to quantify this constraint by extending the trait-gradient analysis (TGA) methodology...
January 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29317729/zircon-evidence-for-incorporation-of-terrigenous-sediments-into-the-magma-source-of-continental-basalts
#14
Zheng Xu, Yong-Fei Zheng, Zi-Fu Zhao
Crustal components may be incorporated into continental basalts by either shallow contamination or deep mixing. While the former proceeds at crustal depths with common preservation of refractory minerals, the latter occurs at mantle depths with rare survival of relict minerals. Discrimination between the two mechanisms has great bearing to subcontinental mantle geochemistry. Here we report the occurrence of relict zircons in Cenozoic continental basalts from eastern China. A combined study of zircon U-Pb ages and geochemistry indicates that detrital zircons were carried by terrigenous sediments into a subcontinental subduction zone, where the zircon were transferred by fluids into the magma sources of continental basalts...
January 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29317684/deep-level-transient-spectroscopic-investigation-of-phosphorus-doped-silicon-by-self-assembled-molecular-monolayers
#15
Xuejiao Gao, Bin Guan, Abdelmadjid Mesli, Kaixiang Chen, Yaping Dan
It is known that self-assembled molecular monolayer doping technique has the advantages of forming ultra-shallow junctions and introducing minimal defects in semiconductors. In this paper, we report however the formation of carbon-related defects in the molecular monolayer-doped silicon as detected by deep-level transient spectroscopy and low-temperature Hall measurements. The molecular monolayer doping process is performed by modifying silicon substrate with phosphorus-containing molecules and annealing at high temperature...
January 9, 2018: Nature Communications
https://www.readbyqxmd.com/read/29317484/chemogenetic-excitation-of-accumbens-projecting-infralimbic-cortical-neurons-blocks-toluene-induced-conditioned-place-preference
#16
Wesley N Wayman, John J Woodward
Abuse rates for inhalants among adolescents continue to be high, yet preclinical models for studying mechanisms underlying inhalant abuse remain limited. Our lab has previously shown that, in male rats, an acute binge-like exposure to toluene vapor that mimics human solvent abuse modifies the intrinsic excitability of medial prefrontal cortex (mPFC) pyramidal neurons projecting to the nucleus accumbens (NAc). These changes showed region (infralimbic; IL vs. prelimbic; PRL), layer (shallow; 2/3 vs. deep; 5/6), target (core vs...
January 9, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29316222/potential-impacts-of-shipping-noise-on-indo-pacific-humpback-dolphins-and-implications-for-regulation-and-mitigation-a-review
#17
Songhai Li, Mingming Liu, Lijun Dong, Jianchen Dong, Ding Wang
Shipping noise is a widespread and relatively loud sound source among human-induced underwater sounds. The impacts of shipping noise are of special concern for Indo-Pacific humpback dolphins (Sousa chinensis), as they inhabit shallow and nearshore habitats and are highly dependent on sound for survival. This study synthesizes our current understanding of the potential impacts of shipping noise on Indo-Pacific humpback dolphins combined with knowledge on sound production and hearing of these animals and the impacts of noise on other whales and dolphins...
January 9, 2018: Integrative Zoology
https://www.readbyqxmd.com/read/29315031/osmolyte-adjustments-as-a-pressure-adaptation-in-deep-sea-chondrichthyan-fishes-an-intraspecific-test-in-arctic-skates-amblyraja-hyperborea-along-a-depth-gradient
#18
Paul H Yancey, Ben Speers-Roesch, Sheila Atchinson, James D Reist, Andrew R Majewski, Jason R Treberg
Accumulation of trimethylamine N-oxide (TMAO) by deep-sea animals is proposed to protect proteins against the destabilizing effects of high hydrostatic pressure (the piezolyte hypothesis). Chondrichthyan fishes (sharks, rays, and chimaeras) provide a unique test of this hypothesis because shallow-living species have elevated TMAO levels to counteract the destabilizing effects of high urea levels accumulated for osmoregulation. Limited interspecific studies of chondrichthyans reveal that increasing depth correlates with decreased urea and increased TMAO levels, suggesting a dynamic balance between destabilizing forces on proteins (high urea, hydrostatic pressure) and TMAO to counteract these forces...
March 2018: Physiological and Biochemical Zoology: PBZ
https://www.readbyqxmd.com/read/29314766/gpsit-an-automated-method-for-evolutionary-analysis-of-nonculturable-ciliated-microeukaryotes
#19
Xiao Chen, Yurui Wang, Yalan Sheng, Alan Warren, Shan Gao
Microeukaryotes are among the most important components of the microbial food web in almost all aquatic and terrestrial ecosystems worldwide. In order to gain a better understanding their roles and functions in ecosystems, sequencing coupled with phylogenomic analyses of entire genomes or transcriptomes are increasingly used to reconstruct the evolutionary history and classification of these microeukaryotes and thus provide a more robust framework for determining their systematics and diversity. More importantly, phylogenomic research usually requires high levels of hands-on bioinformatics experience...
January 4, 2018: Molecular Ecology Resources
https://www.readbyqxmd.com/read/29314069/co-occurring-woody-species-have-diverse-hydraulic-strategies-and-mortality-rates-during-an-extreme-drought
#20
Daniel M Johnson, Jean-Christophe Domec, Z Carter Berry, Amanda M Schwantes, David R Woodruff, Katherine A McCulloh, H Wayne Polley, Remí Wortemann, Jennifer J Swenson, D Scott Mackay, Nate G McDowell, Robert B Jackson
From 2011 to 2013, Texas experienced its worst drought in recorded history. This event provided a unique natural experiment to assess species-specific responses to extreme drought and mortality of four co-occurring woody species: Quercus fusiformis, Diospyros texana, Prosopis glandulosa and Juniperus ashei. We examined hypothesized mechanisms that could promote these species' diverse mortality patterns using post-drought measurements on surviving trees coupled to retrospective process modeling. The species exhibited a wide range of gas exchange responses, hydraulic strategies, and mortality rates...
January 4, 2018: Plant, Cell & Environment
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