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https://www.readbyqxmd.com/read/28817740/influence-of-microtextured-implant-surfaces-on-peri-implantitis-and-its-treatment-a-preclinical-trial
#1
Juan C Rodriguez, Tapan Koticha, Diana L Eubanks, Ivan Rudek, Fred J Molz, Ludovica Chiavaccini, Andrew Claude, Steven Elder, Hom-Lay Wang
PURPOSE: The prevalence of peri-implantitis has increased significantly, forcing clinicians to search for ways to prevent it. Laser-microtextured surfaces promote soft tissue attachment and provide a tight seal around implants. Hence, the aim of this study was to examine the clinical, radiographic, and histologic features of ligature-induced peri-implantitis, as well as the effect of surgical treatment of these induced peri-implantitis lesions on laser-microtextured implants in a controlled animal model...
August 17, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28815629/impulsive-decision-making-in-young-adult-social-drinkers-and-detoxified-alcohol-dependent-patients-a-cross-sectional-and-longitudinal-study
#2
Nadine Bernhardt, Stephan Nebe, Shakoor Pooseh, Miriam Sebold, Christian Sommer, Julian Birkenstock, Ulrich S Zimmermann, Andreas Heinz, Michael N Smolka
BACKGROUND: Impulsive decision making relates to problematic substance use. Specifically, altered delay discounting has been suggested as a behavioral marker for addiction, while other relevant facets of choice impulsivity such as probability discounting or loss aversion are clearly understudied. METHODS: Two studies were performed collecting behavioral data on choice impulsivity with a value-based decision-making battery providing estimates of delay discounting, probability discounting for gains and losses, and loss aversion...
August 17, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28815420/road-map-for-the-structure-based-design-of-selective-covalent-hcv-ns3-4a-protease-inhibitors
#3
REVIEW
Letitia Shunmugam, Pritika Ramharack, Mahmoud E S Soliman
Over the last 2 decades, covalent inhibitors have gained much popularity and is living up to its reputation as a powerful tool in drug discovery. Covalent inhibitors possess many significant advantages including increased biochemical efficiency, prolonged duration and the ability to target shallow, solvent exposed substrate-binding domains. However, rapidly mounting concerns over the potential toxicity, highly reactive nature and general lack of selectivity have negatively impacted covalent inhibitor development...
August 16, 2017: Protein Journal
https://www.readbyqxmd.com/read/28813020/nine-new-triterpene-glycosides-magnumosides-a%C3%A2-a%C3%A2-b%C3%A2-b%C3%A2-c%C3%A2-c%C3%A2-and-c%C3%A2-from-the-vietnamese-sea-cucumber-neothyonidium-massinium-magnum-structures-and-activities-against-tumor-cells-independently-and-in-synergy-with-radioactive-irradiation
#4
Alexandra S Silchenko, Anatoly I Kalinovsky, Sergey A Avilov, Vladimir I Kalinin, Pelageya V Andrijaschenko, Pavel S Dmitrenok, Ekaterina A Chingizova, Svetlana P Ermakova, Olesya S Malyarenko, Tatyana N Dautova
Nine new sulfated triterpene glycosides, magnumosides A₁ (1), A₂ (2), A₃ (3), A₄ (4), B₁ (5), B₂ (6), C₁ (7), C₂ (8) and C₄ (9) as well as a known colochiroside B₂ (10) have been isolated from the tropical Indo-West Pacific sea cucumber Neothynidium (=Massinium) magnum (Phyllophoridae, Dendrochirotida) collected in the Vietnamese shallow waters. The structures of new glycosides were elucidated by 2D NMR spectroscopy and mass-spectrometry. All the isolated new glycosides were characterized by the non-holostane type lanostane aglycones having 18(16)-lactone and 7(8)-double bond and differed from each other by the side chains and carbohydrate moieties structures...
August 16, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28812709/adaptation-to-deep-sea-chemosynthetic-environments-as-revealed-by-mussel-genomes
#5
Jin Sun, Yu Zhang, Ting Xu, Yang Zhang, Huawei Mu, Yanjie Zhang, Yi Lan, Christopher J Fields, Jerome Ho Lam Hui, Weipeng Zhang, Runsheng Li, Wenyan Nong, Fiona Ka Man Cheung, Jian-Wen Qiu, Pei-Yuan Qian
Hydrothermal vents and methane seeps are extreme deep-sea ecosystems that support dense populations of specialized macro-benthos such as mussels. But the lack of genome information hinders the understanding of the adaptation of these animals to such inhospitable environments. Here we report the genomes of a deep-sea vent/seep mussel (Bathymodiolus platifrons) and a shallow-water mussel (Modiolus philippinarum). Phylogenetic analysis shows that these mussel species diverged approximately 110.4 million years ago...
April 3, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28812660/global-determinants-of-zoogeographical-boundaries
#6
Gentile Francesco Ficetola, Florent Mazel, Wilfried Thuiller
The distribution of living organisms on Earth is spatially structured. Early biogeographers identified the existence of multiple zoogeographical regions, characterized by faunas with homogeneous composition that are separated by biogeographical boundaries. Yet, no study has deciphered the factors shaping the distributions of terrestrial biogeographical boundaries at the global scale. Here, using spatial regression analyses, we show that tectonic movements, sharp changes in climatic conditions and orographic barriers determine extant biogeographical boundaries...
March 6, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28812077/a-first-principles-study-of-p-type-defects-in-lacro3
#7
Samira Dabaghmanesh, Nasrin Sarmadian, Erik C Neyts, Bart Partoens
Recently, Sr-doped LaCrO3 has been experimentally introduced as a new p-type transparent conducting oxide. It is demonstrated that substituting Sr for La results in inducing p-type conductivity in LaCrO3. Performing first principles calculations we study the electronic structure and formation energy of various point defects in LaCrO3. Our results for the formation energies show that in addition to Sr, two more divalent defects, Ca and Ba, substituting for La in LaCrO3, behave as shallow acceptors in line with previous experimental reports...
August 16, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28810997/cutaneous-leishmaniasis-in-a-saudi-arabian-soldier-stationed-in-the-united-states
#8
Kelly Laurent, Jason Susong, Eric Fillman, Simon Ritchie
BACKGROUND: Leishmaniasis is a common parasitic disease seen in many parts of the world, especially in areas where current U.S. and international forces are deployed. Approximately 350 million people are thought to be at risk of cutaneous leishmaniasis (CL) with an annual incidence of 1.5 million cases. Over 90% of cutaneous infections with Leishmania occur in the Middle East, Brazil, and Peru. Outbreaks of CL may occur in military personnel deployed to endemic areas. Since the incubation period for symptomatic CL ranges from weeks to months, symptoms may not appear until well after returning to the United States...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28809933/using-light-dependent-scleractinia-to-define-the-upper-boundary-of-mesophotic-coral-ecosystems-on-the-reefs-of-utila-honduras
#9
Jack H Laverick, Dominic A Andradi-Brown, Alex D Rogers
Shallow water zooxanthellate coral reefs grade into ecologically distinct mesophotic coral ecosystems (MCEs) deeper in the euphotic zone. MCEs are widely considered to start at an absolute depth limit of 30m deep, possibly failing to recognise that these are distinct ecological communities that may shift shallower or deeper depending on local environmental conditions. This study aimed to explore whether MCEs represent distinct biological communities, the upper boundary of which can be defined and whether the depth at which they occur may vary above or below 30m...
2017: PloS One
https://www.readbyqxmd.com/read/28808296/effects-of-latitude-and-depth-on-the-beta-diversity-of-new-zealand-fish-communities
#10
Vincent Zintzen, Marti J Anderson, Clive D Roberts, Euan S Harvey, Andrew L Stewart
Marine ecosystems are difficult to sample quantitatively at increasing depth. Hence, few studies attempt to measure patterns of beta diversity for ecological communities in the deep sea. Here we (i) present and quantify large-scale gradients in fish community structure along depth and latitude gradients of the New Zealand EEZ, (ii) obtain rigorous quantitative estimates of these depth (50-1200 m) and latitudinal effects (29.15-50.91°S) and their interaction, and (iii) explicitly model how latitudinal beta diversity of fishes varies with depth...
August 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28808286/source-and-dynamics-of-a-volcanic-caldera-unrest-campi-flegrei-1983-84
#11
Luca De Siena, Giovanni Chiodini, Giuseppe Vilardo, Edoardo Del Pezzo, Mario Castellano, Simona Colombelli, Nicola Tisato, Guido Ventura
Despite their importance for eruption forecasting the causes of seismic rupture processes during caldera unrest are still poorly reconstructed from seismic images. Seismic source locations and waveform attenuation analyses of earthquakes in the Campi Flegrei area (Southern Italy) during the 1983-1984 unrest have revealed a 4-4.5 km deep NW-SE striking aseismic zone of high attenuation offshore Pozzuoli. The lateral features and the principal axis of the attenuation anomaly correspond to the main source of ground uplift during the unrest...
August 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28807733/early-trabeculotomy-ab-externo-in-treatment-of-sturge-weber-syndrome
#12
Yue Wu, Rujing Yu, Di Chen, Li Xu, Li Zhu, Mao Li, Chunyu Guo, Ping Gu, Xiaoxi Lin, Wenyi Guo
PURPOSE: To evaluate the intermediate-term efficacy and safety of trabeculotomy in infant Sturge-Weber syndrome (SWS). DESIGN: Retrospective cohort study. METHODS: All SWS-induced glaucoma patients less than 12 months of age who underwent trabeculotomy at our Ophthalmology Department from August 2011 to March 2017 were reviewed. Baseline demographics, intraocular pressure (IOP), cup-to-disc ratio (C/D) and cornea diameters were noted before surgery...
August 11, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28806691/mercury-contamination-level-and-speciation-inventory-in-lakes-titicaca-uru-uru-bolivia-current-status-and-future-trends
#13
S Guédron, D Point, D Acha, S Bouchet, P A Baya, E Tessier, M Monperrus, C I Molina, A Groleau, L Chauvaud, J Thebault, E Amice, L Alanoca, C Duwig, G Uzu, X Lazarro, A Bertrand, S Bertrand, C Barbraud, K Delord, F M Gibon, C Ibanez, M Flores, P Fernandez Saavedra, M E Ezpinoza, C Heredia, F Rocha, C Zepita, D Amouroux
Aquatic ecosystems of the Bolivian Altiplano (∼3800 m a.s.l.) are characterized by extreme hydro-climatic constrains (e.g., high UV-radiations and low oxygen) and are under the pressure of increasing anthropogenic activities, unregulated mining, agricultural and urban development. We report here a complete inventory of mercury (Hg) levels and speciation in the water column, atmosphere, sediment and key sentinel organisms (i.e., plankton, fish and birds) of two endorheic Lakes of the same watershed differing with respect to their size, eutrophication and contamination levels...
August 11, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28806551/effects-of-agricultural-land-use-on-fluvial-carbon-dioxide-methane-and-nitrous-oxide-concentrations-in-a-large-european-river-the-meuse-belgium
#14
A V Borges, F Darchambeau, T Lambert, S Bouillon, C Morana, S Brouyère, V Hakoun, A Jurado, H-C Tseng, J-P Descy, F A E Roland
We report a data-set of CO2, CH4, and N2O concentrations in the surface waters of the Meuse river network in Belgium, obtained during four surveys covering 50 stations (summer 2013 and late winter 2013, 2014 and 2015), from yearly cycles in four rivers of variable size and catchment land cover, and from 111 groundwater samples. Surface waters of the Meuse river network were over-saturated in CO2, CH4, N2O with respect to atmospheric equilibrium, acting as sources of these greenhouse gases to the atmosphere, although the dissolved gases also showed marked seasonal and spatial variations...
August 11, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28806214/choroidal-nevi-with-focal-choroidal-excavation-and-polypoidal-choroidal-neovascularization
#15
Daniel Simhaee, Rosa Dolz-Marco, K Bailey Freund
PURPOSE: To report two cases of choroidal nevi associated with focal choroidal excavation (FCE) and polypoidal choroidal neovascularization (PCN). METHODS: Report of two patients with choroidal nevi showing FCE and PCN who underwent multimodal imaging including color fundus photography, fluorescein angiography, indocyanine green angiography, fundus autofluorescence, spectral domain optical coherence tomography, swept-source optical coherence tomography, and optical coherence tomography angiography...
August 10, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28805344/high-potential-for-temperate-viruses-to-drive-carbon-cycling-in-chemoautotrophy-dominated-shallow-water-hydrothermal-vents
#16
Eugenio Rastelli, Cinzia Corinaldesi, Antonio Dell'Anno, Michael Tangherlini, Eleonora Martorelli, Michela Ingrassia, Francesco Latino Chiocci, Marco Lo Martire, Roberto Danovaro
Viruses are the most abundant life forms in the world's oceans and they are key drivers of biogeochemical cycles, but their impact on the microbial assemblages inhabiting hydrothermal vent ecosystems is still largely unknown. Here, we analysed the viral life strategies and virus-host interactions in the sediments of a newly discovered shallow-water hydrothermal field of the Mediterranean Sea. Our study reveals that temperate viruses, once experimentally induced to replicate, can cause large mortality of vent microbes, significantly reducing the chemoautotrophic carbon production, while enhancing the metabolism of microbial heterotrophs and the re-cycling of the organic matter...
August 14, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28804665/management-of-traumatic-cataract-with-posterior-capsular-rupture-a-case-report-and-in-vitro-model-study
#17
Wenjuan Wan, Ke Hu, Yan Ji, Can Li
PURPOSE: To investigate the optimal strategy for surgical management of traumatic cataract with posterior capsular rupture. METHODS: We describe four cases of traumatic cataract with posterior capsular rupture and an in vitro model built to evaluate the optimal infusion pressure during surgery. RESULTS: All patients underwent cataract surgery. By using an anterior chamber maintainer to elevate infusion pressure, we safely performed cataract extraction without phacoemulsification...
2017: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/28804262/effects-of-boundary-conditions-on-bistable-behaviour-in-axisymmetrical-shallow-shells
#18
P M Sobota, K A Seffen
Multistable shells are thin-walled structures that have more than one stable state of self-stress. We consider isotropic axisymmetrical shallow shells of arbitrary polynomial shapes using a Föppl-von Kármán analytical model. By employing a Rayleigh-Ritz approach, we identify stable shapes from local minima in the strain energy formulation, and we formally characterize the level of influence of the boundary conditions on the critical geometry for achieving bistable inversion-an effect not directly answered in the literature...
July 2017: Proceedings. Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28803188/remediation-of-internal-phosphorus-loads-with-modified-clays-influence-of-fluvial-suspended-particulate-matter-and-response-of-the-benthic-macroinvertebrate-community
#19
Hongbin Yin, Grant B Douglas, Yongjiu Cai, Cheng Liu, Diego Copetti
Clay-based phosphorus (P) sorbents have been increasingly used as geoengineering materials for the management sediment-derived internal P loading in eutrophic lakes. However, the long-term behavior of these sorbents has remained elusive along with their response to burial under suspended particulate matter (SPM), and their effect on macroinvertebrate communities occupying dynamic regions at the sediment-water interface of shallow and turbid lakes. In this study, field mesocosm experiments were undertaken in Lake Chaohu, China, to study the effects of the application of lanthanum-modified bentonite (LMB) and thermally-modified calcium-rich attapulgite (TCAP) on sediment internal P loading and to assess their influence on macroinvertebrate community structure...
August 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28803052/difference-in-attenuation-among-mn-as-and-fe-in-riverbed-sediments
#20
Saikat Sengupta, Ondra Sracek, Jiin-Shuh Jean, Huai-Jen Yang, Chung-Ho Wang, Sandeep Kar, Ondra Babek, Chi-Yuh Lee, Suvendu Das
We report, for the first time, a detailed study at river water and hyporheic zone systems through collection and analyses of shallow sediments and selected source rocks, pore water, and river water from forty-two locations at the Chianan Plain (CP), SW Taiwan. The study was focused to understand the possible changes in the river water and sediment chemistry as a consequence of high arsenic (mean±SD=71.28±16.24μg/L, n=46) groundwater discharge to three major rivers in the plain. The study shows, except few locations, As concentration in river sediments corresponds to average As concentration in soil and upper crustal abundance and of source rock...
July 20, 2017: Journal of Hazardous Materials
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