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https://www.readbyqxmd.com/read/28316378/high-neutrophil-to-lymphocyte-ratio-predicts-cardiovascular-mortality-in-chronic-hemodialysis-patients
#1
Han Li, Xiangxue Lu, Ruifang Xiong, Shixiang Wang
The neutrophil-to-lymphocyte ratio (NLR) is a novel simple biomarker of inflammation. It has emerged as a predictor of poor prognosis in cancer and cardiovascular disease in general population. But little was known of its prognostic value in chronic hemodialysis (HD) patients. Here we investigated the association between NLR and cardiovascular risk markers, including increased pulse pressure (PP), left ventricular mass index (LVMI) and intima-media thickness (IMT), and mortality in HD patients. Two hundred and sixty-eight HD patients were enrolled in this study and were followed for 36 months...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/28314485/prognostic-implications-of-fasting-plasma-glucose-in-subjects-with-echocardiographic-abnormalities
#2
Manan Pareek, Muthiah Vaduganathan, Deepak L Bhatt, Margrét Leósdóttir, Michael H Olsen
AIMS: To examine whether baseline fasting plasma glucose (FPG) modifies the prognostic role of left ventricular (LV) mass, geometric pattern, and diastolic function, for prediction of cardiovascular morbidity and mortality. METHODS: Population-based cohort study comprising of 1047 men and 456 women with preserved ejection fraction, included between 2002 and 2006, who underwent echocardiography based on groups defined by FPG, measured prior to echocardiography. The clinical endpoint was the composite of cardiovascular events and all-cause mortality, assessed through national and local registries...
February 7, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28248864/association-of-total-cholesterol-and-hdl-c-levels-and-outcome-in-coronary-heart-disease-patients-with-heart-failure
#3
Qin Zhao, Jianfei Li, Jin Yang, Rongshan Li
The aim of the study was to evaluate associations of total cholesterol (TC) and high density lipoprotein cholesterol (HDL-C) levels with prognosis in coronary heart disease (CHD) patients with heart failure (HF).Patients who were angiographical-diagnosis of CHD and echocardiographical-diagnosis of left ventricular ejection fraction (LVEF) < 45% were enrolled. Baseline characteristics were collected and association of TC and HDL-C levels with rehospitalization for HF and all-cause mortality was assessed...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28090249/multimodality-imaging-for-left-ventricular-hypertrophy-severity-grading-a-methodological-review
#4
REVIEW
Maaike Alkema, Ernest Spitzer, Osama I I Soliman, Christian Loewe
Left ventricular hypertrophy (LVH), defined by an increase in left ventricular mass (LVM), is a common cardiac finding generally caused by an increase in pressure or volume load. Assessing severity of LVH is of great clinical value in terms of prognosis and treatment choices, as LVH severity grades correlate with the risk for presenting cardiovascular events. The three main cardiac parameters for the assessment of LVH are wall thickness, LVM, and LV geometry. Echocardiography, with large availability and low cost, is the technique of choice for their assessment...
December 2016: Journal of Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28070840/clinical-and-magnetic-resonance-evolution-of-infarct-like-myocarditis
#5
Riccardo Faletti, Marco Gatti, Ilaria Baralis, Laura Bergamasco, Rodolfo Bonamini, Francesca Ferroni, Massimo Imazio, Silvia Stola, Fiorenzo Gaita, Paolo Fonio
AIMS: To analyse the clinical and magnetic resonance evolution of myocarditis in patients with an "infarct-like" presentation pattern. METHODS: The study is a retrospective analysis of 52 patients with clinical diagnosis of "infarct-like" myocarditis confirmed by CMR as acute myocarditis according to Lake Louise criteria and 6 months follow-up. The CMR protocol included T2-weighted (oedema), early (hyperaemia) and late (fibrosis/necrosis) gadolinium enhancement sequences, according to Lake Louise criteria...
April 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28064152/renal-function-decline-predicted-by-left-atrial-expansion-index-in-non-diabetic-cohort-with-preserved-systolic-heart-function
#6
Shih-Hung Hsiao, Kuan-Rau Chiou
AIMS: Since natriuretic peptide and troponin are associated with renal prognosis and left atrial (LA) parameters are indicators of subclinical cardiovascular abnormalities, this study investigated whether LA expansion index can predict renal decline. METHODS AND RESULTS: This study analysed 733 (69% male) non-diabetic patients with sinus rhythm, preserved systolic function, and estimated glomerular filtration rate (eGFR) higher than 60 mL/min/1.73 m(2). In all patients, echocardiograms were performed and LA expansion index was calculated...
January 7, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/27994093/association-of-anti-citrullinated-protein-or-peptide-antibodies-with-left-ventricular-structure-and-function-in-rheumatoid-arthritis
#7
Laura Geraldino-Pardilla, Cesare Russo, Jeremy Sokolove, William H Robinson, Afshin Zartoshti, Jenny Van Eyk, Justyna Fert-Bober, Joao Lima, Jon T Giles, Joan M Bathon
OBJECTIVE: High levels of ACPAs in RA are associated with more severe arthritis and worse prognosis. However, the role of ACPAs in mediating the increased risk of heart failure in RA remains undefined. We examined whether specific ACPAs were associated with subclinical left ventricular (LV) phenotypes that presage heart failure. METHODS: Sera from RA patients without clinical cardiovascular disease were assayed for specific ACPAs using a custom Bio-Plex bead assay, and their cross-sectional associations with cardiac magnetic resonance-derived LV measures were evaluated...
December 19, 2016: Rheumatology
https://www.readbyqxmd.com/read/27930440/association-of-night-time-home-blood-pressure-with-night-time-ambulatory-blood-pressure-and-target-organ-damage-a-systematic-review-and-meta-analysis
#8
Anastasios Kollias, Angeliki Ntineri, George S Stergiou
OBJECTIVE: Night-time ambulatory blood pressure (nABP) is the most important aspect of the blood pressure profile in terms of prognosis. Novel low-cost home monitors allow automated night-time blood pressure monitoring (nHBP). This study reviewed the evidence on the association of nHBP with nABP and preclinical organ damage. METHODS: Systematic review and meta-analysis. RESULTS: Analysis of six studies (n = 1404) showed pooled difference between nHBP and nABP (SBP/DBP) at 1...
March 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/27908391/prevalence-profile-and-prognosis-of-severe-obesity-in-contemporary-hospitalized-heart-failure-trial-populations
#9
Emer Joyce, Anuradha Lala, Susanna R Stevens, Lauren B Cooper, Omar F AbouEzzeddine, John D Groarke, Justin L Grodin, Eugene Braunwald, Kevin J Anstrom, Margaret M Redfield, Lynne W Stevenson
OBJECTIVES: This study evaluated the prevalence, profile, and prognosis of severe obesity in a large contemporary acute heart failure (AHF) population. BACKGROUND: Better prognosis has been reported for obese heart failure (HF) patients than nonobese HF patients, but in other cardiovascular populations, this effect has not been demonstrated for severely obese patients. METHODS: A cohort of 795 participants with body mass index (BMI) measured at time of admission and complete follow-up were identified from enrollment in 3 contemporary AHF trials (DOSE [Diuretic Strategies Optimization Evaluation], CARRESS-HF [Cardiorenal Rescue Study in Acute Decompensated Heart Failure], and ROSE [Renal Optimization Strategies Evaluation in Acute Heart Failure])...
December 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/27873227/the-relationship-between-aortic-root-size-and-hypertension-an-unsolved-conundrum
#10
Giuseppe Mulè, Emilio Nardi, Massimiliano Morreale, Antonella Castiglia, Giulio Geraci, Dario Altieri, Valentina Cacciatore, Margherita Schillaci, Francesco Vaccaro, Santina Cottone
Thoracic aortic aneurysms rupture and dissection are among the most devastating vascular diseases, being characterized by elevated mortality, despite improvements in diagnostic imaging and surgical techniques.An increased aortic root diameter (ARD) represents the main risk factor for thoracic aortic dissection and rupture and for aortic valve regurgitation.Even though arterial hypertension is commonly regarded as a predisposing condition for the development of thoracic aorta aneurysms, the role of blood pressure (BP) as determinant of aortic root enlargement is still controversial...
November 22, 2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27832460/investigating-the-differences-of-body-mass-index-and-waist-circumference-in-the-follow-up-assessment-of-patients-to-cardiac-rehabilitation-with-acute-coronary-syndrome
#11
Hui Zhao, Jun Ma, Qiru Zhou, Wei Chen, Wei Zhu, Zekun Cai, Hongqiang Lei, Yu Deng, Lin Xu, Jian Qiu
Obesity management is a key point during cardiac rehabilitation. The effect of new index, waist circumference (WC), in the obesity management of cardiac rehabilitation is not clear yet. Therefore, our study compared the WC index to the body mass index (BMI) in the evaluation of obesity management for the patients with acute coronary syndrome (ACS) in a well-designed cardiac rehabilitation program (CRP). Totally 61 patients were enrolled into our study between October 2013 and January 2014 in our hospital. All these patients were requested to participate in the CRP actively for 6 months...
December 2016: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/27754006/js-ish-esh-2-update-on-the-detection-and-follow-up-of-early-hypertensive-heart-disease
#12
Enrico Agabiti Rosei
Current Hypertension Guidelines emphasize the importance of assessing the presence of preclinical organ damage. In fact, an extensive evaluation of organ damage may increase the number of patients classified at high CV risk and therefore strongly influence the clinical management of patients. Hypertensive heart disease remains to date the form of organ damage for which there is the greatest amount of evidence of a strong independent prognostic significance. In the presence of a chronic pressure overload, a parallel addition of sarcomers takes place with an increase in myocyte width, which in turn increases left ventricular wall thickness; myocyte hypertrophy is also associated with apoptosis, collagen deposition and ventricular fibrosis with an impairment of coronary hemodynamics as well, thus profoundly influencing functional properties of the left (and right) ventricle...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27714717/annual-prognostic-factors-in-chronic-heart-failure-in-patients-over-80-years-old
#13
Anna Cichocka-Radwan, Małgorzata Lelonek
BACKGROUND: In the elderly the most common cause of hospitalization and the leading cause of death is heart failure. AIM: The purpose was to determine prognostic factors in chronic heart failure (CHF) in octogenarians and nonagenarians. METHODS: The analysis included 197 consecutive patients older than 80 years old (mean age 83.63±3.01 years; 46.19% of men) hospitalized in 2010-2013 in the Department of Cardiology due to CHF. Sixty two parameters were investigated such as: age, gender, NYHA functional class, body mass index, blood pressure, other comorbidities, the parameters of the 12-lead resting ECG and the echocardiography, the results of basic laboratory tests and selected biomarkers, including N-terminal pro-B-type natriuretic peptide (NT-proBNP), high-sensitive troponin T (hs-TnT), high-sensitive C-reactive protein (hs-CRP)...
December 13, 2016: Kardiologia Polska
https://www.readbyqxmd.com/read/27642917/js-ish-esh-2-update-on-the-detection-and-follow-up-of-early-hypertensive-heart-disease
#14
Enrico Agabiti Rosei
Current Hypertension Guidelines emphasize the importance of assessing the presence of preclinical organ damage. In fact, an extensive evaluation of organ damage may increase the number of patients classified at high CV risk and therefore strongly influence the clinical management of patients. Hypertensive heart disease remains to date the form of organ damage for which there is the greatest amount of evidence of a strong independent prognostic significance. In the presence of a chronic pressure overload, a parallel addition of sarcomers takes place with an increase in myocyte width, which in turn increases left ventricular wall thickness; myocyte hypertrophy is also associated with apoptosis, collagen deposition and ventricular fibrosis with an impairment of coronary hemodynamics as well, thus profoundly influencing functional properties of the left (and right) ventricle...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27627559/the-relationship-of-carotid-arterial-stiffness-and-left-ventricular-concentric-hypertrophy-in-hypertension
#15
MULTICENTER STUDY
Joanna Jaroch, Krystyna Łoboz-Grudzień, Stefania Magda, Maria Florescu, Zbigniew Bociąga, Andrea O Ciobanu, Ewa Kruszyńska, Krzysztof Dudek, Dragos Vinereanu
BACKGROUND: Left ventricular hypertrophy (LVH) and geometry patterns vary in different hemodynamic profiles The concentric hypertrophy (CH) pattern has been proved to have the worst prognosis. OBJECTIVES: The aim of the study was to test the hypothesis that carotid artery stiffness, as a marker of vascular damage, is associated with CH, independently of other potential determinants such as demographic factors (age, sex, BMI), clinical parameters (smoking, diabetes, creatinine level) and hemodynamic variables (blood pressure, pulse pressure [PP])...
March 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/27614542/cumulative-burden-of-myocardial-dysfunction-in-cardiac-amyloidosis-assessed-using-four-chamber-cardiac-strain
#16
Yuichiro Kado, Masaru Obokata, Yasufumi Nagata, Tomoko Ishizu, Karima Addetia, Kazutaka Aonuma, Masahiko Kurabayashi, Roberto M Lang, Masaaki Takeuchi, Yutaka Otsuji
BACKGROUND: The aim of this study was to test the hypothesis that prognosis in patients with cardiac amyloidosis is closely coupled with amyloid burden in all four cardiac chambers. The goal was to evaluate longitudinal strain (LS) in each cardiac chamber and to determine whether LS in specific cardiac chambers is preferentially associated with prognosis over conventional two-dimensional echocardiographic parameters in patients with cardiac amyloidosis. METHODS: Patients with two phenotypes of left ventricular (LV) hypertrophy (cardiac amyloidosis in 55 patients and nonobstructive hypertrophic cardiomyopathy in 40 patients) and 55 healthy subjects were retrospectively enrolled for the simultaneous assessment of LS of all four cardiac chambers in the apical four-chamber view...
September 7, 2016: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/27553872/late-gadolinium-enhancement-and-adverse-outcomes-in-a-contemporary-cohort-of-adult-survivors-of-tetralogy-of-fallot
#17
Richard J Dobson, Ify Mordi, Mark H Danton, Niki L Walker, Hamish A Walker, Nikolaos Tzemos
OBJECTIVE: Myocardial fibrosis has been associated with poorer outcomes in tetralogy of Fallot, however only a handful of studies have assessed its significance in the current era. Our aim was to quantify the amount of late gadolinium enhancement in both the LV and RV in a contemporary cohort of adults with surgically repaired tetralogy of Fallot, and assess the relationship with adverse clinical outcomes. DESIGN: Single centre cohort study SETTING: National tertiary referral center Patients: One hundred fourteen patients with surgically repaired tetralogy of Fallot with median age 29...
August 24, 2016: Congenital Heart Disease
https://www.readbyqxmd.com/read/27508754/-op-5c-07-do-combined-electrocardiographic-and-echocardiographic-markers-of-left-ventricular-hypertrophy-improve-cardiovascular-risk-estimation
#18
C Cuspidi, G L Seravalle, A Re, F Zanchettin, F Bonomi, F Quarti Trevano, R Facchetti, C Sala, M Bombelli, M Tadjc, G Mancia, G Grassi
OBJECTIVE: We estimated the risk of cardiovascular mortality associated with echocardiographic (ECHO) sub-types of left ventricular hypertrophy (LVH), as defined by an up-dated classification, in subjects with and without electrocardiographic (ECG) LVH. To this purpose 1,691 representatives of the general population of Monza, enrolled in the Pressioni Monitorate e Loro Associazioni (PAMELA) study, were included in the present analysis. DESIGN AND METHOD: Cut-points for ECHO-LVH and abnormal LV geometry were derived from reference values of the healthy fraction of the PAMELA population by combining LV mass index, LV diameter and relative wall thickness, ECG-LVH was defined according to Cornell voltage index...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27508688/-op-4a-03-is-white-coat-effect-protective-for-the-prognosis-of-cardiovascular-events
#19
J Bastos, A Araújo, J Pires, J Pinto, P Almeida, J Polonia
OBJECTIVE: HASH(0x49703a0) AIM: It is not well known if systolic white coat effect (WCE), the difference between casual systolic blood pressure (SBPc) and daytime systolic blood pressure determined by ambulatory blood pressure (ABPM), is a marker or not of worst cardiovascular events (CV).The aim of the study was to evaluate the prognostic value of white coat effect in relation to cardiovascular events (CV) stroke (AVC) and coronary events (DC). DESIGN AND METHOD: Casual and ABP were obtained in 1200 hypertensive patients (645 female) age 51 ± 12 years, BMI 27 ± 5 Kg/m2, SBPc 154...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27508558/-op-1c-10-benefits-of-ambulatory-blood-pressure-measurement-in-post-acute-aortic-syndrome-predictors-for-blood-pressure-control-and-importance-of-nocturnal-blood-pressure-influence
#20
P Delsart, G Ledieu, P Devos, J Sobocinski, R Clough, S Haulon, C Mounier-Vehier
OBJECTIVE: Ambulatory blood pressure measurement (ABPM) is recommended to assess optimal blood pressure (BP) control, the most important factor in management post acute aortic syndrome (AAS). Data in this case are lacking. ABPM has previously been shown to be more closely associated with prognosis than clinical values. We assessed these advantages in post AAS.(Figure is included in full-text article.) DESIGN AND METHOD: : We retrospectively collected data from 111 patients with Type B AAS from January 2004 to September 2014...
September 2016: Journal of Hypertension
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