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Gut microbiota NFAT

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https://www.readbyqxmd.com/read/29579238/pulmonary-colonization-resistance-to-pathogens-via-non-canonical-wnt-and-il-17a-by-intranasal-pep27-mutant-immunization
#1
Gyu-Lee Kim, Seungyeop Lee, Se-Jin Kim, Si-On Lee, Suhkneung Pyo, Dong-Kwon Rhee
Colonization resistance has been focused on the gut microbiota against antibiotic resistant strains. However, less research has been performed on respiratory colonization resistance. Since respiratory colonization is the first step of respiratory infections, intervention to prevent colonization would represent a new approach for preventive and therapeutic measures. The Th17 response plays an important role in clearance of respiratory pathogens. Thus, harnessing the Th17 immune response in the mucosal site would be an effective method to design a respiratory mucosal vaccine...
March 22, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/19638260/mechanisms-involved-in-the-immunostimulation-by-probiotic-fermented-milk
#2
Carolina Maldonado Galdeano, Alejandra de Moreno de Leblanc, Esteban Carmuega, Ricardo Weill, Gabriela Perdigón
The intestinal ecosystem contains a normal microbiota, non-immune cells and immune cells associated with the intestinal mucosa. The mechanisms involved in the modulation of the gut immune system by probiotics are not yet completely understood. The present work studies the effect of a fermented milk containing probiotic bacterium Lactobacillus (Lb.) casei DN114001 on different parameters of the gut immune system involved with the nonspecific, innate and adaptive response. BALB/c mice received the probiotic bacterium Lb...
November 2009: Journal of Dairy Research
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