Martin Aichholzer, Philip Rauch, Lucia Kastler, Josef Pichler, Kathrin Aufschnaiter-Hiessböck, Francisco Ruiz-Navarro, Stefan Aspalter, Saskia Hartl, Wolfgang Schimetta, Petra Böhm, Ilja Manakov, Wolfgang Thomae, Matthias Gmeiner, Andreas Gruber, Harald Stefanits
BACKGROUND AND OBJECTIVES: In high-grade glioma (HGG) surgery, intraoperative MRI (iMRI) has traditionally been the gold standard for maximizing tumor resection and improving patient outcomes. However, recent Level 1 evidence juxtaposes the efficacy of iMRI and 5-aminolevulinic acid (5-ALA), questioning the continued justification of iMRI because of its associated costs and extended surgical duration. Nonetheless, drawing from our clinical observations, we postulated that a subset of intricate HGGs may continue to benefit from the adjunctive application of iMRI...
December 22, 2023: Operative Neurosurgery (Hagerstown, Md.)