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https://www.readbyqxmd.com/read/28923760/commonly-used-patient-reported-outcomes-do-not-improve-prediction-of-copd-exacerbations-a-multicenter-4-5-year-prospective-cohort-study
#1
Alexandra Strassmann, Anja Frei, Sarah R Haile, Gerben Ter Riet, Milo A Puhan
BACKGROUND: Several cross-sectional and short-term studies suggest that patient-reported outcomes (PROs) may be useful to (help) predict COPD exacerbations but evidence from long-term prospective cohort studies is missing. Our aim was to assess if PROs add to the prediction of exacerbations. METHODS: 408 primary care COPD patients participated in the multicenter prospective ICE COLD ERIC cohort. PROs included the Chronic Respiratory Disease Questionnaire, the Hospital Anxiety and Depression Scale, the Feeling Thermometer and the LASA Physical Activity Questionnaire (LAPAQ)...
September 15, 2017: Chest
https://www.readbyqxmd.com/read/28919733/cycle-ergometer-and-inspiratory-muscle-training-offer-modest-benefit-compared-with-cycle-ergometer-alone-a-comprehensive-assessment-in-stable-copd-patients
#2
Kai Wang, Guang-Qiao Zeng, Rui Li, Yu-Wen Luo, Mei Wang, Yu-He Hu, Wen-Hui Xu, Lu-Qian Zhou, Rong-Chang Chen, Xin Chen
BACKGROUND: Cycle ergometer training (CET) has been shown to improve exercise performance of the quadriceps muscles in patients with COPD, and inspiratory muscle training (IMT) may improve the pressure-generating capacity of the inspiratory muscles. However, the effects of combined CET and IMT remain unclear and there is a lack of comprehensive assessment. MATERIALS AND METHODS: Eighty-one patients with COPD were randomly allocated to three groups: 28 received 8 weeks of CET + IMT (combined training group), 27 received 8 weeks of CET alone (CET group), and 26 only received 8 weeks of free walking (control group)...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28916294/characteristics-of-older-adults-in-primary-care-who-may-benefit-from-primary-palliative-care-in-the-united-states
#3
Nancy Dudley, Christine S Ritchie, Margaret I Wallhagen, Kenneth E Covinsky, Bruce A Cooper, Kanan Patel, Irena Stijacic-Cenzer, Susan A Chapman
CONTEXT: Older adults with advanced illness and associated symptoms may benefit from primary palliative care, but limited data exist to identify older adults in U.S. primary care to benefit from this care. OBJECTIVES: To describe U.S. primary care visits among adults 65 years and older with advanced illness. METHODS: Cross-sectional analysis of the National Ambulatory and Hospital Ambulatory Medical Care Surveys (2009-2011) was conducted using chi-square tests to compare visits without and with advanced illness to U...
September 12, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28899937/treating-breathlessness-via-the-brain-changes-in-brain-activity-over-a-course-of-pulmonary-rehabilitation
#4
Mari Herigstad, Olivia K Faull, Anja Hayen, Eleanor Evans, F Maxine Hardinge, Katja Wiech, Kyle T S Pattinson
Breathlessness in chronic obstructive pulmonary disease (COPD) is often discordant with airway pathophysiology ("over-perception"). Pulmonary rehabilitation profoundly affects breathlessness, without influencing lung function. Learned associations influence brain mechanisms of sensory perception. We hypothesised that improvements in breathlessness with pulmonary rehabilitation may be explained by changing neural representations of learned associations.In 31 patients with COPD, we tested how pulmonary rehabilitation altered the relationship between brain activity during a breathlessness-related word-cue task (using functional magnetic resonance imaging), and clinical and psychological measures of breathlessness...
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28878693/brain-activation-during-perception-and-anticipation-of-dyspnea-in-chronic-obstructive-pulmonary-disease
#5
Roland W Esser, Maria C Stoeckel, Anne Kirsten, Henrik Watz, Karin Taube, Kirsten Lehmann, Helgo Magnussen, Christian Büchel, Andreas von Leupoldt
Background: Dyspnea is the impairing cardinal symptom in COPD, but the underlying brain mechanisms and their relationships to clinical patient characteristics are widely unknown. This study compared neural responses to the perception and anticipation of dyspnea between patients with stable moderate-to-severe COPD and healthy controls. Moreover, associations between COPD-specific brain activation and clinical patient characteristics were examined. Methods: During functional magnetic resonance imaging, dyspnea was induced in patients with stable moderate-to-severe COPD (n = 17) and healthy control subjects (n = 21) by resistive-loaded breathing...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28876432/hospitalization-due-to-exacerbation-of-copd-real-life-outcomes
#6
Lilia Azzi Collet da Rocha Camargo, Maria Vera Oliveira Castellano, Fábio Checchia Ferreira, Flávio Vieira de Faria, Nelson Carvas
Introduction: Hospitalization due to chronic obstructive pulmonary disease exacerbation (eCOPD) may indicate worse prognosis. It is important to know the profile of hospitalized patients and their outcome of hospitalization to customize and optimize treatment. Method: Evaluation of patients hospitalized for eCOPD, with ≥ 10 pack/years and ≥ 1 previous spirometry with airway obstruction over the course of one year at the pulmonology service of a general hospital, applying: COPD assessment test (CAT); mMRc and Visual Analogue Scale (VAS) for dyspnea; hospitalized anxiety and depression questionnaire (HAD); Divo's comorbidities and Cote index; spirometry; and laboratory tests including number of eosinophils, C-reactive protein (CRP), brain natriuretic protein (BNP)...
June 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28851800/the-chinese-version-of-the-severe-respiratory-insufficiency-questionnaire-for-patients-with-chronic-hypercapnic-chronic-obstructive-pulmonary-disease-receiving-non-invasive-positive-pressure-ventilation
#7
Rongchang Chen, Lili Guan, Weiliang Wu, Zhicong Yang, Xiaoying Li, Qun Luo, Zhenyu Liang, Fengyan Wang, Bingpeng Guo, Yating Huo, Yuqiong Yang, Luqian Zhou
OBJECTIVES: The Severe Respiratory Insufficiency (SRI) questionnaire is the best assessment tool for health-related quality of life in patients with chronic obstructive pulmonary disease (COPD) receiving non-invasive positive pressure ventilation (NIPPV). This study aimed to translate the SRI Questionnaire into Chinese and to validate it. DESIGN: Prospective validation study. SETTING AND PARTICIPANTS: A total of 149 participants with chronic hypercapnic COPD receiving NIPPV completed the study...
August 28, 2017: BMJ Open
https://www.readbyqxmd.com/read/28814848/pathophysiological-mechanism-of-long-term-noninvasive-ventilation-in-stable-hypercapnic-patients-with-copd-using-functional-respiratory-imaging
#8
Bita Hajian, Jan De Backer, Claire Sneyers, Francisca Ferreira, Katherine C Barboza, Glenn Leemans, Wim Vos, Wilfried De Backer
INTRODUCTION: Patients with severe COPD often develop chronic hypercapnic respiratory failure. Their prognosis worsens and they are more likely to develop exacerbations. This has major influence on the health-related quality of life. Currently, there is no information about the success of long-term noninvasive ventilation (NIV) among patients who receive NIV in acute settings. Also, little is known about the pathophysiological mechanism of NIV. METHODS: Ten Global Initiative for Obstructive Lung Disease stage III and IV COPD patients with respiratory failure who were hospitalized following acute exacerbation were treated with NIV using a Synchrony BiPAP device for 6 months...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28807139/recognition-of-anxiety-depression-and-ptsd-in-patients-with-copd-and-chf-who-gets-missed
#9
Chelsea G Ratcliff, Terri L Barrera, Nancy J Petersen, Shubhada Sansgiry, Michael R Kauth, Mark E Kunik, Melinda A Stanley, Jeffrey A Cully
OBJECTIVE: This study sought to identify patient factors associated with mental health (MH) recognition and treatment in medically ill Veterans. METHOD: Retrospective data from patient electronic medical records (EMR) and self-report data were reviewed for 180 Veterans with cardiopulmonary conditions who met diagnostic criteria for anxiety, depression, or posttraumatic stress disorder on the Mini-International Neuropsychiatric Interview. Multivariate logistic regression examined the association of medical record MH recognition and MH service use with patient factors, including anxiety and depression severity, self-efficacy, locus of control, coping, illness intrusiveness, and health-related quality of life (QOL)...
July 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28790808/copd-patients-self-reported-adherence-psychosocial-factors-and-mild-cognitive-impairment-in-pulmonary-rehabilitation
#10
Antonia Pierobon, Elisa Sini Bottelli, Laura Ranzini, Claudio Bruschi, Roberto Maestri, Giorgio Bertolotti, Marinella Sommaruga, Valeria Torlaschi, Simona Callegari, Anna Giardini
In addition to clinical comorbidities, psychological and neuropsychological problems are frequent in COPD and may affect pulmonary rehabilitation delivery and outcome. The aims of the study were to describe a COPD population in a rehabilitative setting as regards the patients depressive symptoms, anxiety, mild cognitive impairment (MCI) and self-reported adherence and to analyze their relationships; to compare the COPD sample MCI scores with normative data; and to investigate which factors might predict adherence to prescribed physical exercise...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28776954/effectiveness-of-pulmonary-rehabilitation-in-copd-patients-receiving-long-term-oxygen-therapy
#11
Hulya Sahin, Yelda Varol, Ilknur Naz, Fevziye Tuksavul
AIM: It has been demonstrated that long-term oxygen therapy increased exercise capacity, improved the quality of life, reduced hospitalization, and increased life expectancy in chronic hypoxemic COPD patients. The present study aims to evaluate the effectiveness of pulmonary rehabilitation (PR) in COPD patients receiving long-term oxygen therapy (LTOT) compared to COPD patients not receiving LTOT. MATERIAL AND METHOD: Chronic hypoxemic COPD patients using LTOT (LTOT group) and COPD patients not receiving LTOT (non-LTOT group) who participated in this study underwent a comprehensive 8-week outpatient PR program...
August 4, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28766459/subjective-cognitive-complaints-and-neuropsychological-performance-in-former-smokers-with-and-without-chronic-obstructive-pulmonary-disease
#12
Amanda M Brunette, Kristen E Holm, Frederick S Wamboldt, Elizabeth Kozora, David J Moser, Barry J Make, James D Crapo, Kimberly Meschede, Howard D Weinberger, Kerrie L Moreau, Russell P Bowler, Karin F Hoth
OBJECTIVE: This study examined the association of perceived cognitive difficulties with objective cognitive performance in former smokers. We hypothesized that greater perceived cognitive difficulties would be associated with poorer performance on objective executive and memory tasks. METHOD: Participants were 95 former smokers recruited from the COPDGene study. They completed questionnaires (including the Cognitive Difficulties Scale [CDS] and the Hospital Anxiety and Depression Scale [HADS]), neuropsychological assessment, and pulmonary function testing...
August 2, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28732827/the-variability-of-respiratory-symptoms-and-associated-factors-in-copd
#13
Marc Miravitlles, José Luis Izquierdo, Cristina Esquinas, Maite Pérez, Myriam Calle, José Luis López-Campos, José Miguel Rodríguez González-Moro, Ciro Casanova, Cristóbal Esteban, Pilar de Lucas
Few studies have investigated the variability of COPD-related symptoms or factors related to symptom variability. This observational, prospective, multicentre study was conducted to describe the number and intensity of morning and night-time respiratory symptoms and their variability over one week using the Night-time and Early Morning Symptoms of COPD Instruments (NiSCI and EMSCI) to evaluate stable COPD patients. Logistic regression analyses were performed to investigate factors associated with symptom variability...
August 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28720670/symptom-clusters-and-quality-of-life-in-subjects-with-copd
#14
Kyeung Eun Lim, Sung Reul Kim, Hyun Kyung Kim, So Ri Kim
BACKGROUND: COPD is one of the most common respiratory diseases. Patients with COPD experience and suffer from various physical and psychological symptoms. We performed this study to identify symptom clusters and the effects on quality of life (QOL) in patients with COPD. METHODS: A total of 130 COPD subjects were recruited from a university hospital in South Korea. Dyspnea, fatigue, depression, anxiety, sleep disturbance, dry mouth, and physical functional status were assessed with structured questionnaires...
July 18, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28665552/comorbidities-in-adults-with-asthma-population-based-cross-sectional-analysis-of-1-4-million-adults-in-scotland
#15
Christopher J Weatherburn, Bruce Guthrie, Stewart W Mercer, Daniel R Morales
BACKGROUND: Comorbidity in people with asthma can significantly increase asthma morbidity and lower adherence to asthma guidelines. OBJECTIVE: The objective of this study was to comprehensively measure the prevalence of physical and mental health comorbidities in adults with asthma using a large nationally representative population. METHODS: Cross-sectional analysis of routine primary care electronic medical records for 1,424,378 adults in the UK, examining the prevalence of 39 comorbidities in people with and without asthma, before and after adjustment for age, sex, social deprivation and smoking status using logistic regression...
June 30, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28664709/the-quality-of-life-of-farmers-with-chronic-obstructive-pulmonary-disease-copd
#16
Joanna Milanowska, Barbara Mackiewicz, Paweł Węgorowski, Janusz Milanowski, Piotr Milanowski, Marta Makara-Studzińska
<b>Introduction and objective.</b> COPD is a medical state characterized by chronically poor airflow, and typically worsens over time. Farmers have an increased risk of COPD because of being exposed to ammonia, hydrogen sulfide, inorganic dust, and organic dust. The quality of life of the ill depends on biomedical as well as psychosocial factors, the impact of which has not been a frequent subject of studies among COPD patients. The aim of the study was to indicate the factors that have negative and positive influence on the quality of life of farmers suffering from COPD...
June 9, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/28651588/perceptions-on-use-of-home-telemonitoring-in-patients-with-long-term-conditions-concordance-with-the-health-information-technology-acceptance-model-a-qualitative-collective-case-study
#17
Jo B Middlemass, Jolien Vos, A Niroshan Siriwardena
BACKGROUND: Health information technology (HIT) may be used to improve care for increasing numbers of older people with long term conditions (LTCs) who make high demands on health and social care services. Despite its potential benefits for reducing disease exacerbations and hospitalisations, HIT home monitoring is not always accepted by patients. Using the Health Information Technology Acceptance Model (HITAM) this qualitative study examined the usefulness of the model for understanding acceptance of HIT in older people (≥60 years) participating in a RCT for older people with Chronic Obstructive Pulmonary Disease (COPD) and associated heart diseases (CHROMED)...
June 26, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28649311/screening-tools-for-evaluation-of-depression-in-chronic-obstructive-pulmonary-disease-copd-a-systematic-review
#18
K Bock, E Bendstrup, O Hilberg, A Løkke
Background: Anxiety and depression are common comorbid disorders in patients with chronic obstructive pulmonary disease (COPD), though estimates of their prevalence vary considerably. Depressive symptoms/depression are important comorbidities in COPD and an increasing interest is shown to these disorders. Depression may lead to reduced quality of life and increased morbidity and mortality. These statements underline the importance of implementing the use of screening instruments for depressive symptoms in a clinical setting...
2017: European Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28635197/depression-anxiety-and-chronic-pain-in-patients-with-chronic-obstructive-pulmonary-disease-the-influence-of-breath
#19
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Beatrice Sacconi
Chronic obstructive pulmonary disease (COPD) is a major public health problems, causing significant mortality and morbidity in the world. It is a complex and progressive disease, characterized by chronic inflammation and dysfunction of the respiratory airways. The article reviews the available information on the potential role of the diaphragm in this disease. The purpose is to identify a potential correlation between symptoms such as depression, anxiety and chronic pain, frequently observed in COPD, with the activity of the diaphragm...
May 25, 2017: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/28634906/delivery-of-brief-cognitive-behavioral-therapy-for-medically-ill-patients-in-primary-care-a-pragmatic-randomized-clinical-trial
#20
Jeffrey A Cully, Melinda A Stanley, Nancy J Petersen, Natalie E Hundt, Michael R Kauth, Aanand D Naik, Kristen Sorocco, Shubhada Sansgiry, Darrell Zeno, Mark E Kunik
BACKGROUND: Few studies have examined the practical effectiveness and implementation potential of brief psychotherapies that integrate mental and physical health. OBJECTIVE: To determine whether an integrated brief cognitive behavioral therapy (bCBT), delivered by mental health providers in primary care, would improve depression, anxiety and quality of life for medically ill veterans. DESIGN: Pragmatic patient-randomized trial comparing bCBT to enhanced usual care (EUC)...
June 20, 2017: Journal of General Internal Medicine
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