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https://www.readbyqxmd.com/read/28540122/presurgical-role-of-mri-tractography-in-a-case-of-extensive-cervicothoracic-spinal-ependymoma
#1
Francesca Granata, Sergio Racchiusa, Enricomaria Mormina, Valeria Barresi, Giada Garufi, Giovanni Grasso, Francesco Maria Salpietro, Marcello Longo, Concetta Alafaci
BACKGROUND: Intramedullary spinal ependymoma is a tumor, hardly characterizable with conventional magnetic resonance (MR) imaging only. MR diffusion tensor imaging (DTI) with three-dimensional fiber-tracking reconstructions allows the evaluation of the relationship between neoplasm and white matter fiber tracts, being a powerful tool in presurgical planning. We present DTI findings in a case of a young female with an extensive cervicothoracic spinal ependymoma. CASE DESCRIPTION: The patient complained of a 2-month history of acute urinary retention, weakness and numbness on the lower limbs and the upper left limb...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28539913/herpes-simplex-virus-type-2-myelitis-case-report-and-review-of-the-literature
#2
Raffaele Nardone, Viviana Versace, Francesco Brigo, Frediano Tezzon, Giulio Zuccoli, Slaven Pikija, Larissa Hauer, Johann Sellner
Non-traumatic myelopathies can result from a wide spectrum of conditions including inflammatory, ischemic, and metabolic disorders. Here, we describe the case of a 60-year old immunocompetent woman who developed acute back pain followed by rapidly ascending flaccid tetraparesis, a C6 sensory level, and sphincter dysfunction within 8 h. Acyclovir and steroids were started on day 2 and herpes simplex virus type 2 (HSV-2) was confirmed by polymerase chain reaction in cerebrospinal fluid. Magnetic resonance imaging revealed a bilateral anterior horn tractopathy expanding from C2 to T2 and cervicothoracic cord swelling...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28526323/-18-f-fdg-pet-ct-helps-in-unmasking-the-great-mimicker-a-case-of-neurosarcoidosis-with-isolated-involvement-of-the-spinal-cord
#3
A Gholamrezanezhad, L Mehta
A 36 year-old male with no significant past medical history presented with lower extremity numbness, gait instability, and urinary and bowel retention of 4 weeks onset. Spine MRI revealed diffuse oedema of cervicothoracic spinal cord with several solid enhancing intramedullary lesions, suggestive of metastases. The (18)F-FDG PET/CT performed to identify the primary malignancy demonstrated mild hypermetabolic foci within the cervicothoracic cord, as well as a mildly hypermetabolic bilateral hilar lymphadenopathy and a mildly hypermetabolic pulmonary nodule, suggestive of sarcoidosis versus metastasis...
May 16, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28525647/evaluation-of-the-effects-of-tanezumab-a-monoclonal-antibody-against-nerve-growth-factor-on-the-sympathetic-nervous-system-in-adult-cynomolgus-monkeys-macaca-fascicularis-a-stereologic-histomorphologic-and-cardiofunctional-assessment
#4
Patrice Belanger, Paul Butler, Mark Butt, Siddhartha Bhatt, Stephen Foote, David Shelton, Mark Evans, Rosalinda Arends, Susan Hurst, Carlin Okerberg, Thomas Cummings, David Potter, Jill Steidl-Nichols, Mark Zorbas
Tanezumab, a humanized monoclonal antibody against nerve growth factor is in development for treatment of chronic pain. Three nonclinical studies assessed effects of clinically relevant and supratherapeutic doses of tanezumab on the sympathetic nervous system (SNS) of adult nonhuman primates. Study 1 evaluated potential effects of subcutaneous (SC) tanezumab (1.2 mg/kg every 8 weeks [Q8W]) on SNS in cynomolgus monkeys for 3 or 6 months and reversibility or persistence of any effects through a non-dosing/recovery period...
May 19, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28505955/the-immediate-effects-of-manual-stretching-and-cervicothoracic-junction-manipulation-on-cervical-range-of-motion-and-upper-trapezius-pressure-pain-thresholds
#5
William J Hanney, Emilio Puentedura, Morey J Kolber, Xinliang Liu, Patrick S Pabian, Scott Cheatham
INTRODUCTION: Myofascial pain is a common impairment treated with various manual interventions including spinal thrust manipulation and stretching; however, the comparative efficacy of each intervention is uncertain. Therefore, the purpose of this investigation was to evaluate thrust manipulation targeting the cervicothoracic junction compared to a manual stretch of the upper trapezius muscle on cervical range of motion and upper trapezius pressure pain thresholds (PPTs). METHODS: Healthy participants with no significant history of neck pain were randomized into a thrust manipulation group, a stretching group, or a control group...
May 5, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28502561/acute-hydrocephalus-due-to-a-primary-malignant-peripheral-nerve-sheath-tumor-of-the-cervicothoracic-junction-a-case-report-and-review-of-the-literature
#6
Y Samanci, H S Togay, R Yakar, F Kabukcuoglu, S E Celik
BACKGROUND: The estimated incidence of malignant nerve sheath tumors is 0.001% per year, and only 2-3% of those tumors involve the spinal nerves. We present a rare case of acute hydrocephalus caused by primary malignant peripheral nerve sheath tumor of the cervicothoracic junction. CASE DESCRIPTION: A 29-year-old previously healthy male patient, except for a history of two previous surgeries for ulnar nerve entrapment and progressive left upper extremity weakness, presented with acute onset somnolence...
May 11, 2017: Neuro-Chirurgie
https://www.readbyqxmd.com/read/28487779/massive-cervicothoracic-subcutaneous-emphysema-and-pneumomediastinum-developing-during-a-dental-hygiene-procedure
#7
Gabriele Bocchialini, Serena Ambrosi, Andrea Castellani
Subcutaneous emphysema is rare during or after dental procedures (usually extractions). Here, we describe the case of a 65-year-old woman who developed massive cervicothoracic subcutaneous emphysema and pneumomediastinum during a dental hygiene procedure employing an artificial airflow. She was diagnosed based on clinical manifestations and computed tomography (CT). CT revealed massive subcutaneous emphysema extending from the superior left eyelid to the diaphragm. We describe the clinical and radiological characteristics of this rare case...
2017: Case Reports in Dentistry
https://www.readbyqxmd.com/read/28480723/extrinsic-esophageal-compression-by-the-vertebral-body
#8
Laura Santos Santamaría, Mercedes Pérez Carreras, José Díaz-Tasende, Gregorio Castellano Tortajada
A 78-year-old woman with hypertension, diabetes, dyslipidemia, and revascularized ischemic heart disease was diagnosed with gastric adenocarcinoma in 2011, with suspected bilateral adrenal metastatic disease, and was treated with subtotal gastrectomy and palliative chemotherapy. A follow-up gastroscopy in 2015 identified a protruding, erosive mid-esophageal lesion suggestive of extrinsic compression or ulcerated submucosal lesion, which had not been described previously. Follow-up was advised, and the lesion persisted after three months...
May 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28462437/clinical-assessment-of-reconstruction-involving-gastric-pull-up-combined-with-free-jejunal-graft-after-total-pharyngolaryngoesophagectomy
#9
Hiroshi Miyata, Keijiro Sugimura, Masaaki Motoori, Yoshiyuki Fujiwara, Takeshi Omori, Masahiro Mun, Masayuki Ohue, Masayoshi Yasui, Norikatsu Miyoshi, Takashi Fujii, Hiroki Tajima, Tomoyuki Kurita, Masahiko Yano
BACKGROUND: Total pharyngolaryngoesophagectomy (PLE) is used as a curative treatment for synchronous laryngopharyngeal and thoracic esophageal cancer or for multiple cancers in the cervical and thoracic esophagus. Gastric pull-up is commonly used after PLE, but postoperative complications are common. The present study evaluated these procedures in patients with esophageal cancer. METHODS: Fourteen patients (7 with synchronous pharyngeal and thoracic esophageal cancer, 4 with synchronous cervical and thoracic esophageal cancer, and 3 with cervicothoracic esophageal cancer) underwent reconstructive surgery after PLE involving gastric pull-up combined with free jejunal graft between 2004 and 2015...
May 1, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28456670/there-is-no-increased-risk-of-adjacent-segment-disease-at-the-cervico-thoracic-junction-following-an-anterior-cervical-discectomy-and-fusion-to-c7
#10
Philip K Louie, Steven M Presciutti, Stephanie E Iantorno, Daniel D Bohl, Kevin Shah, Grant D Shifflett, Howard S An
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) is a very common operative intervention for the treatment of cervical spine degenerative disease in those who have failed non-operative measures. However, studies examining long-term follow up on patients who underwent ACDF reveal evidence of radiographic and clinical degenerative disc disease at the levels adjacent to the fusion construct. Consistent with other junctional regions of the spine, the cervicothoracic junction (CTJ) has significant morphological variations...
April 26, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28451490/incidence-and-outcomes-of-acute-implant-extrusion-following-anterior-cervical-spine-surgery
#11
Gabriel A Smith, Jonathan Pace, Mark Corriveau, Sungho Lee, Thomas E Mroz, Ahmad Nassr, Michael G Fehlings, Robert A Hart, Alan S Hilibrand, Paul M Arnold, David B Bumpass, Ziya Gokaslan, Mohamad Bydon, Jeremy L Fogelson, Eric M Massicotte, K Daniel Riew, Michael P Steinmetz
STUDY DESIGN: Multi-institutional retrospective case series of 8887 patients who underwent anterior cervical spine surgery. OBJECTIVE: Anterior decompression from discectomy or corpectomy is not without risk. Surgical morbidity ranges from 9% to 20% and is likely underreported. Little is known of the incidence and effects of rare complications on functional outcomes following anterior spinal surgery. In this retrospective review, we examined implant extrusions (IEs) following anterior cervical fusion...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28451032/our-experience-in-two-cases-of-type-iv-laryngotracheoesophageal-cleft-ltec-with-a-diagnosis-of-antenatal-esophageal-atresia
#12
Kaan Sonmez, Ramazan Karabulut, Zafer Turkyilmaz, Canan Turkyilmaz, Berrin Isik, Sibel Eryilmaz, Kıvanc Seref, Ebru Ozcan, Gul Meral Hosgoren, Abdullah Can Basaklar
Laryngotracheoesophageal clefts (LTECs) are rare congenital defects that are often accompanied by additional anomalies. The major issues in the treatment of these patients are intraoperative exposure insufficiency, technical difficulty of the operation, and anesthesia problems originating from the respiratory tract. Problems originating from mechanical ventilation and respiratory tract, eating disorders and relapse of fistula are among the problems encountered following surgery. Most of the time, concomitant additional anomalies also worsen the clinical picture...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28450232/ossification-of-the-yellow-ligament-combined-with-ossification-of-the-posterior-longitudinal-ligament-at-the-cervicothoracic-junction-case-report
#13
Shiro Chitoku, Iwao Nishiura, Miyuki Fukuda, Shigeru Amano
A 69-year-old man had progressive pain over his bilateral axillar portion and right lower extremity for one year. Radiology showed cervical canal stenosis with ossification of the yellow ligament (OYL), ossification of the posterior longitudinal ligament (OPLL), and listhesis at the cervicothoracic junction. Posterior decompression therapy was performed and he totally recovered from his symptoms. We report a rare case of the spinal canal stenosis because of OYL and OPLL at the cervicothoracic junction. This case showed the radiological findings of OYL, OPLL, and listhesis, which ultimately compressed the cord and roots at the cervicothoracic junction...
April 24, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28447148/absent-pedicles-in-campomelic-dysplasia
#14
Michael M McDowell, Ozgur Dede, Patrick Bosch, Elizabeth C Tyler-Kabara
OBJECTIVES: The objective of the present study is to report a case of campomelic dysplasia illustrating the absence of cervical and thoracic pedicles. This report reiterates the importance of this clinical peculiarity in the setting of spine instrumentation. MATERIALS AND METHODS: A 10-year-old female patient with campomelic dysplasia presented with progressive kyphoscoliosis and signs of neural compromise. Imaging studies confirmed thoracic level stenosis and demonstrated absence of multiple pedicles in cervical and thoracic spine...
April 26, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28435632/anatomical-considerations-for-insertion-of-pedicular-screw-in-cervicothoracic-junction
#15
Morteza Faghih-Jouibari, Keisan Moazzeni, Amir Amini-Navai, Sara Hanaei, Sina Abdollahzadeh, Ramin Khanmohammadi
Background: This study aimed to investigate the pedicle dimension and angulation in cervicothoracic junction (CTJ) using the findings of computed tomographic (CT) to help accurate insertion of pedicular screw. Methods: Forty three patients with high quality CT images of CTJ were evaluated. Pedicle width (PW), pedicle height (PH), pedicle axis length (PAL), transverse angle (TA) and sagittal angle (SA) were measured bilaterally from C6 to T2. Results: Mean PW was 5.3 mm at C6, 6.2 mm at C7, 8.1 mm at T1 and 6...
October 7, 2016: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/28425761/adult-pilocytic-astrocytoma-of-conus-medullaris-clinical-considerations-and-review-of-the-literature
#16
José Pedro Lavrador, Edson Oliveira, José Pimentel, Sérgio Livraghi
Astrocytomas are responsible for 30% of all primitive intramedullary tumors with cervicothoracic predominance. However, only about one hundred cases of intramedullary pilocytic astrocytomas were described. The authors described the case of a 69 year-old patient presenting with a broad-base gait, bilateral pain and dysesthesia of inferior limbs with a diagnosis of an intra-axial cystic lesion centered to the conus medullaris, diagnosed as pilocytic astrocytoma of conus medullaris (PACM) after surgery. To the best of our knowledge, only two previous reports concerning PACM were made...
April 2017: CNS Oncology
https://www.readbyqxmd.com/read/28412565/the-use-of-a-novel-perfusion-based-cadaveric-simulation-model-with-cerebrospinal-fluid-reconstitution-comparing-dural-repair-techniques-a-pilot-study
#17
Joshua Bakhsheshian, Ben A Strickland, Neil N Patel, Andre M Jakoi, Michael Minneti, Gabriel Zada, Frank L Acosta, Patrick C Hsieh, Jeffrey C Wang, John C Liu, Martin H Pham
BACKGROUND CONTEXT: Watertight dural repair is crucial for both incidental durotomy and closure after intradural surgery. PURPOSE: The study aimed to describe a perfusion-based cadaveric simulation model with cerebrospinal fluid (CSF) reconstitution and to compare spine dural repair techniques. STUDY DESIGN/SETTING: The study is set in a fresh tissue dissection laboratory. SAMPLE SIZE: The sample includes eight fresh human cadavers...
April 12, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28409885/long-term-results-of-the-transmanubrial-osteomuscular-sparing-approach-for-pediatric-tumors
#18
Aziz El Madi, Sabine Irtan, Frédérique Sauvat, Michel Zérah, Gudrun Schleiermacher, Louise Galmiche-Roland, Véronique Minard-Colin, Hervé Brisse, Sabine Sarnacki
BACKGROUND: The complete and safe resection of pediatric cervicothoracic tumors, mostly represented by neurogenic tumors, remains a surgical challenge because of the complex anatomy of this region. The transmanubrial osteomuscular-sparing approach (TOSA) is an alternative to isolated or combined cervical and thoracic approaches enabling the control of supra-aortic vessels and nerves through the thoracic inlet. METHODS: We retrospectively reviewed the tumor characteristics, completeness of resection, morbidity, and long-term outcome of patients with cervicothoracic tumors removed by TOSA between 2000 and 2012 in our institution...
April 14, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28384953/neonatal-airway-compromise-by-a-giant-cervicothoracic-venous-haemangioma
#19
Janardhan Shenoy, Anita Coutinho, Sowmini P Kamath, Suresh Pai, Santosh Pv Rai
Haemangiomas are most common non-malignant vascular tumours of infancy. Here, we describe an antenatally detected mass over the neck causing compressive respiratory compromise at birth requiring resuscitative measures at birth. The mass showed increased vascularity on Contrast Enhanced Computed Tomography (CECT) with extension upto superior mediastinum. Surgical excision was required following failure to medical measures with steroids and propranolol. Histopathology confirmed it to be a venous haemangioma. This case highlights that these benign lesions may reach large sizes and antenatal detection may help in planning effective delivery and resuscitative measures...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28361367/three-column-osteotomy-for-correction-of-cervical-and-cervicothoracic-deformities-alignment-changes-and-early-complications-in-a-multicenter-prospective-series-of-23-patients
#20
Justin S Smith, Christopher I Shaffrey, Renaud Lafage, Virginie Lafage, Frank J Schwab, Han Jo Kim, Justin K Scheer, Themistocles Protopsaltis, Peter Passias, Gregory Mundis, Robert Hart, Brian Neuman, Eric Klineberg, Richard Hostin, Shay Bess, Vedat Deviren, Christopher P Ames
PURPOSE: Three-column osteotomy (3CO), including pedicle subtraction osteotomy (PSO) and vertebral column resection (VCR), can provide powerful alignment correction for adult cervical deformity (ACD). Our objective was to assess alignment changes and early complications associated with 3CO for ACD. METHODS: ACD patients treated with 3CO with minimum 90-day follow-up were identified from a prospectively collected multicenter ACD database. Complications within 90-days of surgery and pre- and postoperative radiographs were collected...
March 30, 2017: European Spine Journal
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