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https://www.readbyqxmd.com/read/27924670/safety-of-iphone-retinal-photography
#1
Sheng Chiong Hong, Giles Wynn-Williams, Graham Wilson
BACKGROUND: With the advancement in mobile technology, smartphone retinal photography is becoming a popular practice. However, there is limited information about the safety of the latest smartphones used for retinal photography. AIMS: This study aims to determine the photobiological risk of iPhone 6 and iPhone 6 plus when used in conjunction with a 20Diopter condensing lens for retinal photography. METHOD: iPhone 6 and iPhone 6 plus (Apple, Cupertino, CA) were used in this study...
December 7, 2016: Journal of Medical Engineering & Technology
https://www.readbyqxmd.com/read/27924333/a-classical-description-of-subnanometer-resolution-by-atomic-features-in-metallic-structures
#2
S Trautmann, J Aizpurua, I Götz, A Undisz, J Dellith, H Schneidewind, M Rettenmayr, V Deckert
Recent experiments have evidenced sub-nanometer resolution in plasmonic-enhanced probe spectroscopy. Such a high resolution cannot be simply explained using the commonly considered radii of metallic nanoparticles on plasmonic probes. In this contribution the effects of defects as small as a single atom found on spherical plasmonic particles acting as probing tips are investigated in connection with the spatial resolution provided. The presence of abundant edge and corner sites with atomic scale dimensions in crystalline metallic nanoparticles is evident from transmission electron microscopy (TEM) images...
December 7, 2016: Nanoscale
https://www.readbyqxmd.com/read/27923941/the-effect-of-differences-in-day-and-night-lighting-distributions-on-drivers-speed-perception
#3
Jonathan D Kim, John A Perrone, Robert B Isler
Previous research has shown that changes to contrast levels in the visual environment caused by fog can affect drivers' perceptions of speed. It is not easy, however, to extrapolate these results to other driving scenarios in which contrast is affected, such as during nighttime driving, because the measure of contrast is more complex when considering factors such as the illumination provided by headlights. Therefore, we investigated the differences in lighting distribution patterns between day- and nighttime driving on speed perception using prerendered 3D scenarios representing driving on a rural road...
December 5, 2016: Perception
https://www.readbyqxmd.com/read/27923877/poison-and-alarm-the-asian-hornet-vespa-velutina-uses-sting-venom-volatiles-as-alarm-pheromone
#4
Ya-Nan Cheng, Ping Wen, Shi-Hao Dong, Ken Tan, James C Nieh
In colonial organisms, alarm pheromones can provide a key fitness advantage by enhancing colony defense and warning of danger. Learning which species use alarm pheromone and the key compounds involved therefore enhances our understanding of how this important signal has evolved. However, our knowledge of alarm pheromones is more limited in the social wasps and hornets as compared to the social bees and ants. Vespa velutina is an economically important and widespread hornet predator that attacks humans and honey bees...
December 6, 2016: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27923845/numerical-and-spatial-patterning-of-yeast-meiotic-dna-breaks-by-tel1
#5
Neeman Mohibullah, Scott Keeney
The Spo11-generated double-strand breaks (DSBs) that initiate meiotic recombination are dangerous lesions that can disrupt genome integrity, so meiotic cells regulate their number, timing, and distribution. Mechanisms of this regulation remain poorly understood. Here, we use Spo11-oligonucleotide complexes, a byproduct of DSB formation, to reveal aspects of the contribution of the Saccharomyces cerevisiae DNA damage-responsive kinase Tel1 (ortholog of mammalian ATM). A tel1Δ mutant has globally increased amounts of Spo11-oligonucleotide complexes and altered Spo11-oligonucleotide lengths, consistent with conserved roles for Tel1 in control of DSB number and processing...
December 6, 2016: Genome Research
https://www.readbyqxmd.com/read/27922180/going-domestic-importing-the-study-abroad-experience-the-development-of-a-multicultural-new-york-city-study-away-program
#6
Susan Hayes Lane, Carolyn Huffman, Dana E Brackney, Alyssa Cuddy
PROBLEM: Significant off-campus domestic study away experiences have been shown to be a transformative active learning environment for students and achieve similar learning outcomes as study abroad programs. METHODS: This manuscript describes the conception, development, and pedagogical approach of a faculty-led domestic study away experience in New York City for pre-licensure and post-licensure nursing students as an active learning strategy for developing cultural competence...
December 6, 2016: Nursing Forum
https://www.readbyqxmd.com/read/27920135/nobel-prize-honors-autophagy-discovery
#7
(no author information available yet)
Japanese cell biologist Yoshinori Ohsumi, PhD, was awarded this year's Nobel Prize in Physiology or Medicine for his discovery of autophagy. His groundbreaking studies in yeast cells illuminated how cells break down and recycle damaged material, a process that is critical to the survival of both normal cells and some cancer cells.
December 2016: Cancer Discovery
https://www.readbyqxmd.com/read/27920082/doctors-perspectives-on-psa-testing-illuminate-established-differences-in-prostate-cancer-screening-rates-between-australia-and-the-uk-a-qualitative-study
#8
Kristen Pickles, Stacy M Carter, Lucie Rychetnik, Vikki A Entwistle
OBJECTIVES: To examine how general practitioners (GPs) in the UK and GPs in Australia explain their prostate-specific antigen (PSA) testing practices and to illuminate how these explanations are similar and how they are different. DESIGN: A grounded theory study. SETTING: Primary care practices in Australia and the UK. PARTICIPANTS: 69 GPs in Australia (n=40) and the UK (n=29). We included GPs of varying ages, sex, clinical experience and patient populations...
December 5, 2016: BMJ Open
https://www.readbyqxmd.com/read/27919664/photodynamic-therapy-with-green-light-for-the-treatment-of-vulvar-lichen-sclerosus-preliminary-results
#9
B J Osiecka, K Jurczyszyn, P Nockowski, M Murawski, P Ziółkowski
INTRODUCTION: The standard treatment for lichen sclerosus (LS) is symptomatic and is primarily based on the chronic use of corticosteroids, sometimes resulting in unsatisfactory effects. Therefore, other non-pharmacological methods are being sought, which are less aggravating for the patient. LS can be treated topically by using photodynamic therapy (PDT) based on 5-aminolevulinic acid (5-ALA). Unfortunately, therapy with the red light is often connected with severe local pain during the illumination...
December 2, 2016: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/27919430/carbon-dioxide-insufflation-deflects-airborne-particles-from-an-open-surgical-wound-model
#10
P Kokhanenko, G Papotti, J E Cater, A C Lynch, J A van der Linden, C J T Spence
BACKGROUND: Surgical site infections remain a significant burden on healthcare systems and may benefit from new countermeasures. AIM: To assess the merits of open surgical wound CO2 insufflation via a gas diffuser to reduce airborne contamination, and to determine the distribution of CO2 in and over a wound. METHODS: An experimental approach with engineers and clinical researchers was employed to measure the gas flow pattern and motion of airborne particles in a model of an open surgical wound in a simulated theatre setting...
November 21, 2016: Journal of Hospital Infection
https://www.readbyqxmd.com/read/27918537/the-genome-and-transcriptome-of-japanese-flounder-provide-insights-into-flatfish-asymmetry
#11
Changwei Shao, Baolong Bao, Zhiyuan Xie, Xinye Chen, Bo Li, Xiaodong Jia, Qiulin Yao, Guillermo Ortí, Wenhui Li, Xihong Li, Kristin Hamre, Juan Xu, Lei Wang, Fangyuan Chen, Yongsheng Tian, Alex M Schreiber, Na Wang, Fen Wei, Jilin Zhang, Zhongdian Dong, Lei Gao, Junwei Gai, Takashi Sakamoto, Sudong Mo, Wenjun Chen, Qiong Shi, Hui Li, Yunji Xiu, Yangzhen Li, Wenteng Xu, Zhiyi Shi, Guojie Zhang, Deborah M Power, Qingyin Wang, Manfred Schartl, Songlin Chen
Flatfish have the most extreme asymmetric body morphology of vertebrates. During metamorphosis, one eye migrates to the contralateral side of the skull, and this migration is accompanied by extensive craniofacial transformations and simultaneous development of lopsided body pigmentation. The evolution of this developmental and physiological innovation remains enigmatic. Comparative genomics of two flatfish and transcriptomic analyses during metamorphosis point to a role for thyroid hormone and retinoic acid signaling, as well as phototransduction pathways...
December 5, 2016: Nature Genetics
https://www.readbyqxmd.com/read/27918474/hazard-management-dealt-by-safety-professionals-in-colleges-the-impact-of-individual-factors
#12
Tsung-Chih Wu, Chi-Hsiang Chen, Nai-Wen Yi, Pei-Chen Lu, Shan-Chi Yu, Chien-Peng Wang
Identifying, evaluating, and controlling workplace hazards are important functions of safety professionals (SPs). The purpose of this study was to investigate the content and frequency of hazard management dealt by safety professionals in colleges. The authors also explored the effects of organizational factors/individual factors on SPs' perception of frequency of hazard management. The researchers conducted survey research to achieve the objective of this study. The researchers mailed questionnaires to 200 SPs in colleges after simple random sampling, then received a total of 144 valid responses (response rate = 72%)...
December 3, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27918293/structural-and-theoretical-characterization-of-a-new-twisted-4-substituted-terpyridine-compound-4-isoquinolin-4-yl-2-2-6-2-terpyridine
#13
Juan Granifo, Beatriz Arévalo, Rubén Gaviño, Sebastián Suárez, Ricardo Baggio
4'-Substituted derivatives of 2,2':6',2''-terpyridine with N-containing heteroaromatic substituents, such as pyridyl groups, might be able to coordinate metal centres through the extra N-donor atom, in addition to the chelating terpyridine N atoms. The incorporation of these peripheral N-donor sites would also allow for the diversification of the types of noncovalent interactions present, such as hydrogen bonding and π-π stacking. The title compound, C24H16N4, consists of a 2,2':6',2''-terpyridine nucleus (tpy), with a pendant isoquinoline group (isq) bound at the central pyridine (py) ring...
December 1, 2016: Acta Crystallographica. Section C, Structural Chemistry
https://www.readbyqxmd.com/read/27917896/astragaloside-iv-ameliorates-allergic-inflammation-by-inhibiting-key-initiating-factors-in-the-initial-stage-of-sensitization
#14
Kai-Fan Bao, Xi Yu, Xiao Wei, Li-Li Gui, Hai-Liang Liu, Xiao-Yu Wang, Yu Tao, Guo-Rong Jiang, Min Hong
To illuminate the anti-allergy mechanism of astragaloside IV (AS-IV), we assessed its effects in a murine model of allergic contact dermatitis (ACD). AS-IV administered in the sensitization phase, rather than in the elicitation phase, dramatically alleviated the symptoms of allergic inflammation. We hypothesized that AS-IV exerts its anti-allergy effects by regulating the production of key pro-allergic cytokines based on the fact that interleukin (IL)-33 and thymic stromal lymphopoietin (TSLP) levels increase significantly in the initial stage of the sensitization phase...
December 5, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27916715/360-degree-trabeculotomy-for-medically-refractory-glaucoma-following-cataract-surgery-and-juvenile-open-angle-glaucoma
#15
Maria E Lim, Jennifer B Dao, Sharon F Freedman
PURPOSE: While angle surgeries show good success in primary congenital glaucoma, reported success in glaucoma following cataract surgery (GFCS) and juvenile open angle glaucoma (JOAG) is variable and with relatively short follow-up. We evaluated longer-term outcomes of 360-trabeculotomy for medically-refractory GFCS and JOAG. DESIGN: Retrospective case series. METHODS: First operated eyes of consecutive patients with medically-refractory GFCS and JOAG in a single-surgeon pediatric glaucoma practice who underwent illuminated microcatheter-assisted 360-trabeculotomy from 2/2008-6/2015 were reviewed...
December 1, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27916634/lateral-heterogeneity-of-the-proton-potential-along-the-thylakoid-membranes-of-chloroplasts
#16
Alexey V Vershubskii, Boris V Trubitsin, Vladimir I Priklonskii, Alexander N Tikhonov
This work is devoted to critical analysis and reexamination of the problem of lateral heterogeneity of the trans-thylakoid pH difference (ΔpH=pHout-pHin) in thylakoid membranes of chloroplasts. Correct measurements of ΔpH may be complicated by nonuniform partitioning of the protons pumped into the lumen of granal (stacked) and stroma-exposed thylakoids. We have compared results of ΔpH estimations in isolated bean chloroplasts by two different methods. One of the methods is based on the use of pH-sensitive spin-probes...
December 1, 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27915252/photoinactivation-of-bacteria-by-endogenous-photosensitizers-and-exposure-to-visible-light-of-different-wavelengths-a-review-on-existing-data
#17
M Hessling, B Spellerberg, K Hoenes
Visible light has strong disinfectant properties, a fact which is not well known in comparison to the antibacterial properties of UV light. This review compiles the published data on bacterial inactivation caused by visible light and endogenous photosensitizers. It evaluates more than 100 published studies containing information on about 40 different bacterial species irradiated within the spectral range from 380 to 780 nm. In the available data a high variability of the photoinactivation sensitivity is observed, which may be caused by undefined illumination conditions...
December 2, 2016: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/27914890/biomass-and-oil-production-by-chlorella-vulgaris-and-four-other-microalgae-effects-of-salinity-and-other-factors
#18
Tiyaporn Luangpipat, Yusuf Chisti
Five nominally freshwater microalgae (Chlorella vulgaris, Choricystis minor, Neochloris sp., Pseudococcomyxa simplex, Scenedesmus sp.) with a known ability to produce high-levels of lipids for possible use as fuel oils were evaluated for their ability to thrive and produce lipids in seawater and brackish water. Only C. vulgaris was found to thrive and produce lipids in full strength seawater. Seawater tolerant strains of C. vulgaris are unusual. Lipid productivity in nutrient sufficient seawater exceeded 37mgL(-1)d(-1) and was nearly 2-fold greater than in freshwater...
November 30, 2016: Journal of Biotechnology
https://www.readbyqxmd.com/read/27914879/what-can-animal-research-tell-us-about-the-link-between-androgens-and-social-competition-in-humans
#19
REVIEW
Matthew J Fuxjager, Brian C Trainor, Catherine A Marler
The relationship between androgenic hormones, like testosterone (T), and aggression is extensively studied in human populations. Yet, while this work has illuminated a variety of principals regarding the behavioral and phenotypic effects of T, it is also hindered by inherent limitations of performing research on people. In these instances, animal research can be used to gain further insight into the complex mechanisms by which T influences aggression. Here, we explore recent studies on T and aggression in numerous vertebrate species, although we focus primarily on males and on a New World rodent called the California mouse (Peromyscus californicus)...
November 30, 2016: Hormones and Behavior
https://www.readbyqxmd.com/read/27914753/store-operated-calcium-entry-from-concept-to-structural-mechanisms
#20
REVIEW
Peter B Stathopulos, Mitsuhiko Ikura
In 1986, J.W. Putney presented a model for capacitative calcium (Ca(2+)) entry conveying that depletion of endoplasmic reticulum stored Ca(2+) levels leads to activation of plasma membrane Ca(2+) channels which mediate influx of Ca(2+) from the extracellular space into cells. Presently, the biomolecules regulating this process, more widely known as store operated Ca(2+) entry (SOCE) which is vital to myriad signaling pathways in health and disease, are known and the focus of intense structural biology research aiming to illuminate the atomic mechanisms of function...
November 25, 2016: Cell Calcium
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