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systemic lupus erthematosus

Bilal Bin Abdullah, Syed Mustafa Ashraf, Mohammed Zoheb, Nida Nausheen
A 22-year-old female patient presented to the Emergency Department of a tertiary care hospital with symptoms of headache and nausea. She has been on a regular follow-up for the preceding three and a half years after being diagnosed as systemic lupus erythematosus (SLE). She had been treated earlier for SLE nephritis in the same institution, and had two relapses of nephrotic syndrome in the last three and a half years for which she had been treated and had achieved complete remission. All possibilities of headaches in background of SLE were considered...
September 2012: Iranian Journal of Medical Sciences
Anthony Virtue, Hong Wang, Xiao-feng Yang
The discovery of miRNAs has revolutionized the way we examine the genome, RNA products, and the regulation of transcription and translation. Their ability to modulate protein expression through mRNA degradation and translation repression resulted in avid scientific interest in miRNAs over the past decade. This research has led to findings that indicate miRNAs can regulate an array of cellular functions such as cellular apoptosis, proliferation, differentiation, and metabolism. Specifically, the capability of miRNAs to finely-tune gene expression naturally lends itself to immune system regulation which requires precise control for proper activity...
2012: Journal of Hematology & Oncology
Hyoun-Ah Kim, Jin-Young Nam, Ja-Young Jeon, Jeong-Mi An, Ju-Yang Jung, Chang-Bum Bae, Chang-Hee Suh
PURPOSE: Growth arrest-specific protein 6 (Gas6) has been suggested to be a biomarker of disease activity in patients with systemic lupus erthematosus (SLE). We investigated the clinical significance of this protein in Korean SLE. METHODS: Blood samples were collected from 150 SLE patients and 50 normal controls (NC). In addition, follow-up samples were collected from 50 SLE patients. RESULTS: Serum Gas6 levels of SLE patients (43.01 ± 28...
January 2013: Journal of Clinical Immunology
Shane G Silver, H Chih-Ho Hong, Patricia T Ting, Nigel J Ball
BACKGROUND: Kikuchi-Fujimoto's necrotizing lymphadenitis (KFNL) is a rare, benign, self-limited condition characterized by constitutional symptoms, lymphadenopathy, and skin lesions. OBJECTIVE: We report a case of KFNL in a 43-year-old East Indian woman with a ten-year history of discoid lupus erythematosus (DLE) of the scalp and a three-month history of a erythematous plaque on the left nasal bridge, cervical lymphadenopathy, and fever. Skin biopsy samples were taken from the face and lymph node...
November 2004: Journal of Cutaneous Medicine and Surgery
No abstract text is available yet for this article.
August 18, 1962: Nederlands Tijdschrift Voor Geneeskunde
No abstract text is available yet for this article.
August 13, 1960: JAMA: the Journal of the American Medical Association
No abstract text is available yet for this article.
February 27, 1965: Die Medizinische Welt
Z Ulcová-Gallová, H Suchová, P Zemancik, V Novotný
Systemic lupus erthematosus (SLE) has been very often associated with complication in reproduction. 29 SLE women divided into two groups A (10 patients aged 18-36 years) and B (19 patients aged 42-67 years) were queried with regard to general, obstetric and SLE history by the use of a questionnaire. Serum of each patient was tested for interleukin-6 (by ELISA), sperm antibodies (by mixed antiglobulin reaction and tray agglutination test) and zona pellucida antibodies (passive haemagglutination test and ELISA methods)...
1996: Zentralblatt Für Gynäkologie
A S Russell, J S Percy, W M Rigal, G L Wilson
No abstract text is available yet for this article.
May 1974: Annals of the Rheumatic Diseases
K B Pieper, M A Rapoff, M R Purviance, C B Lindsley
Compliance with regimens for pediatric rheumatic diseases is often poor, and few studies have evaluated strategies for improving compliance. This study utilized relatively simple behavioral and educational strategies to improve compliance with prednisone for three patients with pediatric rheumatic diseases (systemic lupus erthematosus and dermatomyositis). These strategies were implemented in a pediatric rheumatology setting and resulted in improved compliance that was maintained at 6- and 12-month follow-up...
December 1989: Arthritis Care and Research: the Official Journal of the Arthritis Health Professions Association
M Oishi, M Takano, K Miyachi, Y Ichikawa, M Homma
Our patient and those of Agnello et al. had identical clinical symptoms such as erythema multiforme, arthralgias and angioneurotic edema and both differed from systemic lupus erthematosus in several important points, i.e., in spite of marked hypocomplementemia the nephropathy is not prominent and it needs high-dose steroids to eliminate the clinical and serological abnormalities. In addition to the features reported by Agnello et al. we found increased viral antibody titers in our patient's sera.
1976: International Archives of Allergy and Applied Immunology
S Shu, T Provost, M B Croxdale, M Reichlin, E H Beutner
Skin nuclear speckled IgG deposition was noted in seven patients. The patients' clinical courses satisfied at least four of the preliminary criteria of the American Rheumatism Association for the diagnosis of systemic lupus erthematosus (SLE). Examination of approximately 700 additional biopsies from patiets with SLE, connective tissue and various skin diseases as well as normal individuals, failed to demonstrate similar nuclear immunoglobulin deposition. Sera from these seven patients had higher titre, complement fixing anti-nuclear antibodies (ANA) of IgG class which produced a speckled nuclear fluorescent pattern...
February 1977: Clinical and Experimental Immunology
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