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https://www.readbyqxmd.com/read/29792104/association-of-hip-and-foot-factors-with-patellar-tendinopathy-jumper-s-knee-in-athletes
#1
Luciana D Mendonça, Juliana M Ocarino, Natália F N Bittencourt, Luciana G Macedo, Sérgio T Fonseca
Study Design Clinical measurement, cross-sectional. Background Investigations on the causes of patellar tendinopathy (PT) should consider impairments at the hip and foot/ankle since they are known to influence movement patterns and affect patellar tendon loading. Objectives To investigate, by means of CART analysis, impairments of the hip and foot/ankle that are associated with PT in volleyball and basketball athletes. Methods One-hundred and ninety athletes were assessed for impairments of the hip and foot/ankle including: shank-forefoot alignment (SFA), ankle dorsiflexion range of motion (DF ROM), iliotibial band flexibility, passive hip internal rotation (IR) ROM, and hip external rotator (ER) and hip abductor isometric strength...
May 23, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29791452/validity-and-reliability-of-two-alternate-versions-of-the-montreal-cognitive-assessment-hong-kong-version-for-screening-of-mild-neurocognitive-disorder
#2
Adrian Wong, Stanley Yiu, Ziad Nasreddine, Kam-Tat Leung, Alexander Lau, Yannie O Y Soo, Lawrence Ka-Sing Wong, Vincent Mok
OBJECTIVE: Repeated testing using the Montreal Cognitive Assessment (MoCA) increases risks for practice effects which may bias measurements of cognitive change. The objective of this study is to develop two alternate versions of the MoCA (Hong Kong version; HK-MoCA) and to investigate the validity and reliability of the alternate versions in patients with DSM-5 Mild Neurocognitive Disorder (Mild NCD) and cognitively healthy controls. METHODS: Concurrent validity and inter-scale agreement were examined by Pearson correlation of the total scores between the original and alternate versions and the Bland-Altman Method...
2018: PloS One
https://www.readbyqxmd.com/read/29788983/role-of-pulmonary-hemodynamics-in-determining-6-minute-walk-test-result-in-atrial-septal-defect-an-observational-study
#3
Supomo Supomo, Handy Darmawan, Adika Zhulhi Arjana
BACKGROUND: The presence of altered pulmonary hemodynamics in adult patients with atrial septal defect (ASD) is common. However, there are no observational studies which evaluate the impact of altered pulmonary hemodynamics on the 6-min walk test (6MWT) result. This study aimed to investigate the role of pulmonary hemodynamics in determining 6MWT result of patients with ASD. METHOD: Forty-six consecutive adult patients with ASD were included in this study. Right heart catheterization was performed to obtain the pulmonary hemodynamics profile...
May 22, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29785842/circular-rna-0068669-as-a-new-biomarker-for-hepatocellular-carcinoma-metastasis
#4
Ting Yao, Qingqing Chen, Zhouwei Shao, Zhihua Song, Liyun Fu, Bingxiu Xiao
BACKGROUND: Circular RNAs (circRNAs) play important roles in disease occurrence. However, the roles of circRNAs in the diagnosis of hepatocellular carcinoma (HCC) are largely unknown. The aim of this study is to investigate the clinical diagnostic values of hsa_circ_0068669 (Alias: hsa_circ_103561), one of the representative HCC-associated circRNAs. METHODS: Hsa_circ_0068669 expression levels in HCC tissues, HCC cell lines, and chronic hepatitis tissues were detected by real-time quantitative reverse transcription-polymerase chain reaction...
May 21, 2018: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29785210/adipose-tissue-derived-cytokines-and-their-correlations-with-clinical-characteristics-in-vietnamese-patients-with-type-2-diabetes-mellitus
#5
Nguyen Linh Toan, Nguyen Van Hoan, Doan Viet Cuong, Nguyen Viet Dung, Phan The Dung, Ngo Thu Hang, Do Thi Huyen Dieu, Dang Thanh Chung, Ho Anh Son, Pham Xuan Phong, George Binh Lenon, Doan Van De, Hoang Van Tong
Background: Adipokines are involved in the pathogenesis of metabolic disorders including obesity and type 2 diabetes mellitus (T2DM). This study investigates the levels of leptin, resistin, visfatin, secreted frizzled-related protein 5 (SFRP5), monocyte chemoattractant protein-1 (MCP-1) and retinol-binding protein 4 (RBP4) and their correlations with clinical parameters of overweight and T2DM. Methods: We recruited overweight 50 patients with T2DM, 88 non-overweight patients with T2DM, 29 overweight and 100 non-overweight individuals devoid of T2DM for this study...
2018: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29784058/fat-suppressed-gadolinium-enhanced-isotropic-high-resolution-3d-gre-t1wi-for-predicting-small-node-metastases-in-patients-with-rectal-cancer
#6
Yan Chen, Xinyue Yang, Ziqiang Wen, Baolan Lu, Xiaojuan Xiao, Bingqi Shen, Shenping Yu
BACKGROUND: To investigate the application value of fat-suppressed gadolinium-enhanced isotropic high-resolution 3D-GRE-T1WI in regional nodes with different short-axis diameter ranges in rectal cancer, especially in nodes ≤5 mm. METHODS: Patients with rectal adenocarcinoma confirmed by postoperative histopathology were included, and all the patients underwent preoperative 3.0 T rectal magnetic resonance imaging (MRI) and total mesorectal excision (TME) within 2 weeks after an MR scan...
May 21, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29783973/erythrocyte-microrna-sequencing-reveals-differential-expression-in-relapsing-remitting-multiple-sclerosis
#7
Kira Groen, Vicki E Maltby, Rodney A Lea, Katherine A Sanders, J Lynn Fink, Rodney J Scott, Lotti Tajouri, Jeannette Lechner-Scott
BACKGROUND: There is a paucity of knowledge concerning erythrocytes in the aetiology of Multiple Sclerosis (MS) despite their potential to contribute to disease through impaired antioxidant capacity and altered haemorheological features. Several studies have identified an abundance of erythrocyte miRNAs and variable profiles associated with disease states, such as sickle cell disease and malaria. The aim of this study was to compare the erythrocyte miRNA profile of relapsing-remitting MS (RRMS) patients to healthy sex- and age-matched controls...
May 21, 2018: BMC Medical Genomics
https://www.readbyqxmd.com/read/29780779/sonographic-evaluation-of-bladder-wall-thickness-in-women-with-lower-urinary-tract-dysfunction
#8
Un Ju Shin, Jihye Koh, Jiwon Song, Soyun Park, Eun Joo Park, Chung-Hoon Kim, Sung Hoon Kim, Byung Moon Kang, Hee Dong Chae
Objective: To investigate the correlation between bladder wall thickness (BWT) measured by ultrasonography and lower urinary tract dysfunction (LUTD) in patients with lower urinary tract symptoms (LUTS). Methods: Forty-eight women with LUTS who underwent urodynamic study and BWT by ultrasonography as outpatients were studied. We assessed LUTS during a medical examination by interview. The thinnest part of the bladder wall was measured by a transabdominal ultrasonography...
May 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29779870/central-adiposity-markers-plasma-lipid-profile-and-cardiometabolic-risk-prediction-in-overweight-obese-individuals
#9
Rocco Barazzoni, Gianluca Gortan Cappellari, Annamaria Semolic, Mario Ius, Michela Zanetti, Antonio Gabrielli, Pierandrea Vinci, Gianfranco Guarnieri, Giorgio Simon
BACKGROUND: Waist circumference (WC) is the currently recommended marker of central fat for cardiometabolic risk screening. Alternative surrogate markers have been recently proposed to better reflect the metabolic impact of central fat accumulation per se, based on WC normalization by height (Weight-to-Height Ratio - WtoH; Body Roundness Index - BRI) or body mass index (BMI) without (A Body Shape Index - ABSI) or with inclusion of plasma triglyceride and HDL-cholesterol concentrations (Visceral Adiposity Index - VAI)...
May 8, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29779770/normalised-quantitative-polymerase-chain-reaction-for-diagnosis-of-tuberculosis-associated-uveitis
#10
Manas Ranjan Barik, Soveeta Rath, Rohit Modi, Rajkishori Rana, Mamatha M Reddy, Soumyava Basu
Polymerase chain reaction (PCR)-based diagnosis of tuberculosis-associated uveitis (TBU) in TB-endemic countries is challenging due to likelihood of latent mycobacterial infection in both immune and non-immune cells. In this study, we investigated normalised quantitative PCR (nqPCR) in ocular fluids (aqueous/vitreous) for diagnosis of TBU in a TB-endemic population. Mycobacterial copy numbers (mpb64 gene) were normalised to host genome copy numbers (RNAse P RNA component H1 [RPPH1] gene) in TBU (n = 16) and control (n = 13) samples (discovery cohort)...
May 2018: Tuberculosis
https://www.readbyqxmd.com/read/29778931/monitoring-tool-usage-in-surgery-videos-using-boosted-convolutional-and-recurrent-neural-networks
#11
Hassan Al Hajj, Mathieu Lamard, Pierre-Henri Conze, Béatrice Cochener, Gwenolé Quellec
This paper investigates the automatic monitoring of tool usage during a surgery, with potential applications in report generation, surgical training and real-time decision support. Two surgeries are considered: cataract surgery, the most common surgical procedure, and cholecystectomy, one of the most common digestive surgeries. Tool usage is monitored in videos recorded either through a microscope (cataract surgery) or an endoscope (cholecystectomy). Following state-of-the-art video analysis solutions, each frame of the video is analyzed by convolutional neural networks (CNNs) whose outputs are fed to recurrent neural networks (RNNs) in order to take temporal relationships between events into account...
May 9, 2018: Medical Image Analysis
https://www.readbyqxmd.com/read/29778898/examining-the-diagnostic-accuracy-of-static-postural-stability-measures-in-differentiating-among-knee-osteoarthritis-patients-with-mild-and-moderate-to-severe-radiographic-signs
#12
Nahid Pirayeh, Mohammad-Jafar Shaterzadeh-Yazdi, Hossein Negahban, Mohammad Mehravar, Neda Mostafaee, Amal Saki-Malehi
BACKGROUND: Clinicians need a reliable and accurate tools that can best identify and classify balance impairments between mild and moderate to severe grades of knee osteoarthritis (OA). RESEARCH QUESTION: This study was designed to investigate the accuracy of postural measurements to discriminate between these two groups of knee OA. METHODS: A total of 130 patients with knee OA based on the Kellgren-Lawrence (KL) grading scale were categorized into 65 patients with mild (a KL grade≤ 2) and 65 patient with moderate to severe (a KL grade≥3) radiographic sign...
May 12, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29777573/quantiferon-cytomegalovirus-assay-a-potentially-useful-tool-in-the-evaluation-of-cmv-specific-cd8-t-cell-reconstitution-in-pediatric-hematopoietic-stem-cell-transplant-patients
#13
Bilio Paouri, Alexandra Soldatou, Eftihia Petrakou, Maria Theodosaki, Charalampos Tsentidis, Katerina Kaisari, Christina Oikonomopoulou, Minos Matsas, Eugenios Goussetis
Pediatric HSCT recipients are at high risk for CMV reactivation due to their immature immune system and therapy following transplantation. Reconstitution of CMV-specific T-cell immunity is associated with control and protection against CMV. The clinical utility of monitoring CMV-specific CMI to predict CMV viremia in pediatric HSCT patients using the Quantiferon-CMV (QIAGEN® ) test was investigated prospectively. Thirty-seven pediatric allogeneic HSCT recipients were enrolled from 3/2010-6/2012. CMV viremia was detected via weekly real-time PCR...
May 18, 2018: Pediatric Transplantation
https://www.readbyqxmd.com/read/29777457/a-nomogram-to-predict-anastomotic-leakage-in-open-rectal-surgery-hope-or-hype
#14
Johannes Klose, Ignazio Tarantino, Armin von Fournier, Moritz J Stowitzki, Yakup Kulu, Thomas Bruckner, Claudia Volz, Thomas Schmidt, Martin Schneider, Markus W Büchler, Alexis Ulrich
BACKGROUND: Anastomotic leakage is the most dreaded complication after rectal resection and total mesorectal excision, leading to increased morbidity and mortality. Formation of a diverting ileostomy is generally performed to protect anastomotic healing. Identification of variables predicting anastomotic leakage might help to select patients who are under increased risk for the development of anastomotic leakage prior to surgery. The objective of this study was to assess the applicability of a nomogram as prognostic model for the occurrence of anastomotic leakage after rectal resection in a cohort of rectal cancer patients...
May 18, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29777455/combined-preoperative-albi-and-fib-4-is-associated-with-recurrence-of-hepatocellular-carcinoma-after-curative-hepatectomy
#15
Rui Liao, De-Wei Li, Cheng-You Du, Ming Li
BACKGROUND AND PURPOSE: Chronic inflammatory response is a risk factor for hepatocarcinogenesis and recurrence. This study aimed to develop a nomogram incorporating the combined albumin-bilirubin (ALBI) and fibrosis-4 (FIB-4) scores and the peritumoral inflammation score (PIS) to predict postoperative recurrence-free survival (RFS) of hepatocellular carcinoma (HCC). METHODS: The prognostic roles of preoperative ALBI and FIB-4 scores for HCC recurrence were investigated, and a nomogram was developed...
May 18, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29774933/-clinicopathological-characteristics-and-prognostic-factor-analysis-of-carcinoma-in-remnant-stomach-cancer-at-peking-university-cancer-hospital
#16
Yinkui Wang, Ziyu Li, Chenggen Jin, Xiangji Ying, Chao Gao, Yuchen Wang, Qiyan Xiao, Yan Zhang, Yufan Chen, Lianhai Zhang, Jiafu Ji
OBJECTIVE: To investigate the interval time to canceration, clinicopathological characteristics and prognostic factors of carcinoma in remnant stomach (CRS) in patients with primary benign diseases or primary malignant tumors. METHODS: Based on the criteria of the definition of CRS proposed by Japanese Gastric Cancer Association in 2017, a retrospective analysis was conducted on clinicopathological characteristics of patients diagnosed with CRS at Peking University Cancer Hospital from March 1992 to March 2017...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29774420/lysophosphatidylcholine-as-a-predictor-of-postoperative-complications-after-colorectal-cancer-surgery
#17
Akihisa Matsuda, Marina Yamada, Satoshi Matsumoto, Nobuyuki Sakurazawa, Takeshi Yamada, Takeshi Matsutani, Masao Miyashita, Eiji Uchida
PURPOSE: Lysophosphatidylcholine (LPC), which is generated from phosphatidylcholine (PC) and metabolized by autotaxin (ATX), modulates immune responses via its anti-inflammatory property. We investigated the association between LPC and postoperative complications (POCs) after colorectal cancer surgery (CRC). METHODS: The subjects of this study were 43 patients who underwent surgery for CRC. Peripheral blood samples were collected preoperatively and immediately after surgery, and on postoperative days (PODs) 1, 3, 5, and 7...
May 17, 2018: Surgery Today
https://www.readbyqxmd.com/read/29773108/-adiponectin-inhibits-proliferation-and-induces-apoptosis-in-colorectal-cancer-hct116-cells
#18
Manling Huang, Zhitao Chen, Dan Xu, Heng Zhang, Shengbin Sun, Jie Wu
Objective To investigate the relationship between serum adiponectin level and risk of colorectal cancer, and to explore the effect of recombinant adiponectin on the proliferation and apoptosis of colorectal cancer HCT116 cells. Methods Serum adiponectin levels in patients with colorectal cancer and healthy controls were dectected by ELISA. With the level of adiponectin as a risk factor, ROC curve was acquired using SPSS software. HCT116 cells were treated with recombinant adiponectin (2.5, 5, 10, 20 μg/mL)...
March 2018: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
https://www.readbyqxmd.com/read/29772188/hamstring-and-ankle-flexibility-deficits-are-weak-risk-factors-for-hamstring-injury-in-professional-soccer-players-a-prospective-cohort-study-of-438-players-including-78-injuries
#19
Nicol van Dyk, Abdulaziz Farooq, Roald Bahr, Erik Witvrouw
BACKGROUND: Hamstring injuries remain a significant injury burden in sports such as soccer that involve high-speed running. It has repeatedly been identified as the most common noncontact injury in elite male soccer, representing 12% of all injuries. As the incidence of hamstring injuries remains high, investigations are aimed at better understanding how to prevent hamstring injuries. Stretching to improve flexibility is commonly used in elite-level sports, but risk factor studies have reported contradicting results, leading to unclear conclusions regarding flexibility as a risk factor for hamstring injuries...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29771409/mir-299-5p-targets-cell-cycle-to-promote-cell-proliferation-and-progression-of-osteosarcoma
#20
C-L Zhang, L-B Li, C She, Y Xie, D-W Ge, Q-R Dong
OBJECTIVE: Osteosarcoma is a common primary bone tumor with high mortality. MicroRNA (miRNA, miR) is a small RNA with 20-25 nucleotides, which could regulate diverse biological processes by targeting 3'-UTR of gene to degrade it. MiR-299-5p has been reported to participate in the progression of many diseases, but the role in osteosarcoma is still uncertain. The aim of this work was to investigate the expression of miR-299-5p in osteosarcoma and its clinical significance. MATERIALS AND METHODS: The datasets of osteosarcoma miRNA was searched in Gene Expression Omnibus (GEO) datasets, including GSE65071, GSE39040, and GSE39055...
May 2018: European Review for Medical and Pharmacological Sciences
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