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https://www.readbyqxmd.com/read/29147144/effects-of-spectral-smearing-of-stimuli-on-the-performance-of-auditory-steady-state-response-based-brain-computer-interface
#1
Jong Ho Hwang, Kyoung Won Nam, Dong Pyo Jang, In Young Kim
There have been few reports that investigated the effects of the degree and pattern of a spectral smearing of stimuli due to deteriorated hearing ability on the performance of auditory brain-computer interface (BCI) systems. In this study, we assumed that such spectral smearing of stimuli may affect the performance of an auditory steady-state response (ASSR)-based BCI system and performed subjective experiments using 10 normal-hearing subjects to verify this assumption. We constructed smearing-reflected stimuli using an 8-channel vocoder with moderate and severe hearing loss setups and, using these stimuli, performed subjective concentration tests with three symmetric and six asymmetric smearing patterns while recording electroencephalogram signals...
December 2017: Cognitive Neurodynamics
https://www.readbyqxmd.com/read/29121385/a-controlled-comparison-of-auditory-steady-state-responses-and-pure-tone-audiometry-in-patients-with-hearing-loss
#2
Raman Wadhera, Sharad Hernot, Sat Paul Gulati, Vijay Kalra
We performed a prospective interventional study to evaluate correlations between hearing thresholds determined by pure-tone audiometry (PTA) and auditory steady-state response (ASSR) testing in two types of patients with hearing loss and a control group of persons with normal hearing. The study was conducted on 240 ears-80 ears with conductive hearing loss, 80 ears with sensorineural hearing loss, and 80 normal-hearing ears. We found that mean threshold differences between PTA results and ASSR testing at different frequencies did not exceed 15 dB in any group...
October 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29092566/linear-combination-of-auditory-steady-state-responses-evoked-by-co-modulated-tones
#3
François Guérit, Jeremy Marozeau, Bastian Epp
Up to medium intensities and in the 80-100-Hz region, the auditory steady-state response (ASSR) to a multi-tone carrier is commonly considered to be a linear sum of the dipoles from each tone specific ASSR generator. Here, this hypothesis was investigated when a unique modulation frequency is used for all carrier components. Listeners were presented with a co-modulated dual-frequency carrier (1 and 4 kHz), from which the modulator starting phase Φi of the 1-kHz component was systematically varied. The results support the hypothesis of a linear superposition of the dipoles originating from different frequency specific ASSR generators...
October 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/29079460/optimized-auditory-transcranial-alternating-current-stimulation-improves-individual-auditory-temporal-resolution
#4
Alina Baltus, Sven Wagner, Carsten Hermann Wolters, Christoph Siegfried Herrmann
BACKGROUND: Temporal resolution of cortical, auditory processing mechanisms is suggested to be linked to peak frequency of neuronal gamma oscillations in auditory cortex areas (individual gamma frequency, IGF): Individuals with higher IGF tend to have better temporal resolution. HYPOTHESIS: Modulating ongoing gamma activity with transcranial alternating current stimulation (tACS) is expected to improve performance in gap detection (GD) tasks (shorter GD thresholds) if the frequency is higher and to decrease GD performance (longer GD thresholds) if the frequency is lower than IGF...
October 17, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/29076484/-features-of-cytokines-profile-in-various-forms-of-systemic-inflammatory-response-syndrome-in-patients-with-acute-calculous-cholecystitis
#5
Dzh N Gadzhiev, N Dzh Gadzhiev, Z B Mamedova
AIM: Comparative evaluation of systemic concentration of some cytokines in various forms of SIR in patients with acute calculous cholecystitis. MATERIAL AND METHODS: The study included 32 patients with acute calculous cholecystitis and SIR. According to ASSR/SCCM criteria SIR 2 was in 11, SIR 3 - in 8, SIR 4 - in 7 patients, 6 patients had sepsis. Serum TNF-α, IL-6, IL-4 and IL-10 were determined prior to surgery, in 3 and 7 days postoperatively by using of ELISA...
2017: Khirurgiia
https://www.readbyqxmd.com/read/29054059/enhancement-of-sludge-reduction-by-ultrasonic-pretreatment-and-packing-carriers-in-the-anaerobic-side-stream-reactor-performance-sludge-characteristics-and-microbial-community-structure
#6
Cheng Cheng, Zhen Zhou, Zhan Qiu, Jiyuan Yang, Wei Wu, Hongjian Pang
Effects of ultrasonic pretreatment and packing carriers on sludge reduction, settleability, dewaterability and microbial community structure in the anaerobic side-stream reactor (ASSR) were investigated with three anaerobic reactors operated in parallel. Ultrasonication from 3.65% in the ASSR to 5.08%, and packing carriers further enhanced the efficiency to 19.2%. Ultrasonic pretreatment of sludge decreased oxidation-reduction potential in ASSR and enhanced the release of intracellular substances. The deterioration of sludge settleability and dewaterability in the ASSR after ultrasonic pretreatment was improved by packing carriers...
October 10, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29051085/40hz-auditory-steady-state-response-in-schizophrenia-sensitivity-to-stimulation-type-clicks-versus-flutter-amplitude-modulated-tones
#7
Inga Griskova-Bulanova, Kastytis Dapsys, Sigita Melynyte, Aleksandras Voicikas, Valentinas Maciulis, Sergejus Andruskevicius, Milena Korostenskaja
Auditory steady-state response (ASSR) at 40Hz has been proposed as a potential biomarker for schizophrenia. The ASSR studies in patients have used click stimulation or amplitude-modulated tones. However, the sensitivity of 40Hz ASSRs to different stimulation types in the same group of patients has not been previously evaluated. Two stimulation types for ASSRs were tested in this study: (1) 40Hz clicks and (2) flutter-amplitude modulated tones. The mean phase-locking index, evoked amplitude and event-related spectral perturbation values were compared between schizophrenia patients (n=26) and healthy controls (n=20)...
October 16, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/29036430/delta-vs-gamma-auditory-steady-state-synchrony-in-schizophrenia
#8
Krishna C Puvvada, Ann Summerfelt, Xiaoming Du, Nithin Krishna, Peter Kochunov, Laura M Rowland, Jonathan Z Simon, L Elliot Hong
Background: Delta band (1-4 Hz) neuronal responses support the precision and stability of auditory processing, and a deficit in delta band synchrony may be relevant to auditory domain symptoms in schizophrenia patients. Methods: Delta band synchronization elicited by a 2.5 Hz auditory steady state response (ASSR) paradigm, along with those from theta (5 Hz), alpha (10 Hz), beta (20 Hz), gamma (40 Hz), and high gamma (80 Hz) frequency ASSR, were compared in 128 patients with schizophrenia, 108 healthy controls, and 55 first-degree relatives (FDR) of patients...
June 20, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28917446/amplitude-modulation-rate-dependent-topographic-organization-of-the-auditory-steady-state-response-in-human-auditory-cortex
#9
Nathan Weisz, Chrysoula Lithari
Periodic modulations of an acoustic feature, such as amplitude over a certain frequency range, leads to phase locking of neural responses to the envelope of the modulation. Using electrophysiological methods this neural activity pattern, also called the auditory steady-state response (aSSR), is visible following frequency transformation of the evoked response as a clear spectral peak at the modulation frequency. Despite several studies employing the aSSR that show, for example, strongest responses for ∼40 Hz and an overall right-hemispheric dominance, it has not been investigated so far to what extent within auditory cortex different modulation frequencies elicit aSSRs at a homogenous source or whether the localization of the aSSR is topographically organized in a systematic manner...
September 11, 2017: Hearing Research
https://www.readbyqxmd.com/read/28857787/stability-of-auditory-steady-state-responses-over-time
#10
Maaike Van Eeckhoutte, Robert Luke, Jan Wouters, Tom Francart
OBJECTIVES: Auditory steady state responses (ASSRs) are used in clinical practice for objective hearing assessments. The response is called steady state because it is assumed to be stable over time, and because it is evoked by a stimulus with a certain periodicity, which will lead to discrete frequency components that are stable in amplitude and phase over time. However, the stimuli commonly used to evoke ASSRs are also known to be able to induce loudness adaptation behaviorally. Researchers and clinicians using ASSRs assume that the response remains stable over time...
August 26, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28844789/protocadherin-10-alters-%C3%AE-oscillations-amino-acid-levels-and-their-coupling-baclofen-partially-restores-these-oscillatory-deficits
#11
Russell G Port, Christopher Gajewski, Elizabeth Krizman, Holly C Dow, Shinji Hirano, Edward S Brodkin, Gregory C Carlson, Michael B Robinson, Timothy P L Roberts, Steven J Siegel
Approximately one in 45 children have been diagnosed with Autism Spectrum Disorder (ASD), which is characterized by social/communication impairments. Recent studies have linked a subset of familial ASD to mutations in the Protocadherin 10 (Pcdh10) gene. Additionally, Pcdh10's expression pattern, as well as its known role within protein networks, implicates the gene in ASD. Subsequently, the neurobiology of mice heterozygous for Pcdh10 (Pcdh10(+/-)) has been investigated as a proxy for ASD. Male Pcdh10(+/-) mice have demonstrated sex-specific deficits in social behavior, recapitulating the gender bias observed in ASD...
August 24, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/28796603/ear-eeg-based-objective-hearing-threshold-estimation-evaluated-on-normal-hearing-subjects
#12
Christian Bech Christensen, James Michael Harte, Thomas Lunner, Preben Kidmose
OBJECTIVE: Hearing threshold levels have been estimated successfully in the clinic using the objective EEG-based technique of auditory steady state response (ASSR). The recent method of ear-EEG could enable ASSR hearing tests to be made in everyday life, rather than in a specialized clinic, enabling cheaper and easier monitoring of audiometric thresholds over time. The objective of the current study was to evaluate the feasibility of ear-EEG in audiometric characterization of auditory sensitivity thresholds...
August 9, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28756648/objective-assessment-of-hearing-during-second-stage-of-tympanoplasty-surgical-technique-and-measurement-methodology-presented-in-ten-patients
#13
Kazimierz Niemczyk, Krzysztof Morawski, Rafael Delgado, Antoni Bruzgielewicz, Magdalena Lachowska
In this paper, a complete integrated method of intraoperative monitoring of hearing (IOMH) during ossiculoplasty performed via posterior tympanotomy is presented. The method integrates auditory steady state responses (ASSR) with Laser-Doppler Vibrometry (LDV) and allows intraoperative optimization of ossicular prosthesis positioning and coupling. Both ASSR and LDV are acquired simultaneously. The results of the integrated measurements are analyzed and evaluated automatically on-line which makes this strategy unaffected by individual differences in interpretations of collected recordings...
July 30, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28692981/a-new-method-to-test-the-efficiency-of-cochlear-implant-artifacts-removal-from-auditory-evoked-potentials
#14
Virginie Attina, Faten Mina, Pierre Stahl, Yvan Duroc, Evelyne Veuillet, Eric Truy, Hung Thai-Van
Auditory Evoked Potentials (AEPs) are of great interest to objectively evaluate the audition in cochlear implant (CI) recipients. However, these measures are impeded by CI stimulation electrical artifacts present in the EEG. In a first part, this study investigates the use of a hybrid model approximating CI patient data. This model gives access to both uncontaminated and denoised data, thus allowing for the evaluation of CI artifact removal methods. Here the efficiency of Independent Component Analysis (ICA) is evaluated in the context of Auditory Steady State Responses (ASSRs)...
July 6, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28680486/longitudinal-comparison-of-auditory-steady-state-evoked-potentials-in-preterm-and-term-infants-the-maturation-process
#15
Ana Constantino Sousa, Dayane Domeneghini Didoné, Pricila Sleifer
Introduction  Preterm neonates are at risk of changes in their auditory system development, which explains the need for auditory monitoring of this population. The Auditory Steady-State Response (ASSR) is an objective method that allows obtaining the electrophysiological thresholds with greater applicability in neonatal and pediatric population. Objective  The purpose of this study is to compare the ASSR thresholds in preterm and term infants evaluated during two stages. Method  The study included 63 normal hearing neonates: 33 preterm and 30 term...
July 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/28659780/estimation-of-human-workload-from-the-auditory-steady-state-response-recorded-via-a-wearable-electroencephalography-system-during-walking
#16
Yusuke Yokota, Shingo Tanaka, Akihiro Miyamoto, Yasushi Naruse
Workload in the human brain can be a useful marker of internal brain state. However, due to technical limitations, previous workload studies have been unable to record brain activity via conventional electroencephalography (EEG) and magnetoencephalography (MEG) devices in mobile participants. In this study, we used a wearable EEG system to estimate workload while participants walked in a naturalistic environment. Specifically, we used the auditory steady-state response (ASSR) which is an oscillatory brain activity evoked by repetitive auditory stimuli, as an estimation index of workload...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28635497/desynchronisation-of-auditory-steady-state-responses-related-to-changes-in-interaural-phase-differences-an-objective-measure-of-binaural-hearing
#17
Charlotte Vercammen, Astrid van Wieringen, Jan Wouters, Tom Francart
OBJECTIVE: Binaural processing can be measured objectively as a desynchronisation of phase-locked neural activity to changes in interaural phase differences (IPDs). This was reported in a magnetoencephalography study for 40 Hz amplitude modulated tones. The goal of this study was to measure this desynchronisation using electroencephalography and explore the outcomes for different modulation frequencies. DESIGN: Auditory steady-state responses (ASSRs) were recorded to pure tones, amplitude modulated at 20, 40 or 80 Hz...
February 14, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28599607/the-accuracy-of-objective-threshold-determination-at-low-frequencies-comparison-of-different-auditory-brainstem-response-abr-and-auditory-steady-state-response-assr-methods
#18
Jacqueline Frank, Izet Baljić, Sebastian Hoth, Dirk Eßer, Orlando Guntinas-Lichius
OBJECTIVE: The hearing threshold at 500 Hz was estimated using five methods which are suitable for the low frequency range: Low-Chirp BERA (LCBERA), Notched-noise BERA (NNBERA), Narrow band CE-Chirp BERA (NBCBERA) and Narrow band CE-Chirp ASSR (NBCASSR) (40/90 Hz). The slope of the discrimination function of each method was used for determination of the most efficient method. The threshold values were compared and the corresponding odds ratios (OR) were calculated. DESIGN: All methods were applied to each subject...
May 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28521049/22q11-2-deletion-syndrome-is-associated-with-impaired-auditory-steady-state-gamma-response
#19
Kit Melissa Larsen, Giovanni Pellegrino, Michelle Rosgaard Birknow, Trine Nørgaard Kjær, William Frans Christiaan Baaré, Michael Didriksen, Line Olsen, Thomas Werge, Morten Mørup, Hartwig Roman Siebner
Background: The 22q11.2 deletion syndrome confers a markedly increased risk for schizophrenia. 22q11.2 deletion carriers without manifest psychotic disorder offer the possibility to identify functional abnormalities that precede clinical onset. Since schizophrenia is associated with a reduced cortical gamma response to auditory stimulation at 40 Hz, we hypothesized that the 40 Hz auditory steady-state response (ASSR) may be attenuated in nonpsychotic individuals with a 22q11.2 deletion...
May 17, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28425497/single-dose-memantine-improves-cortical-oscillatory-response-dynamics-in-patients-with-schizophrenia
#20
Gregory A Light, Wen Zhang, Yash B Joshi, Savita Bhakta, Jo A Talledo, Neal R Swerdlow
Aberrant gamma-band (30-80 Hz) oscillations may underlie cognitive deficits in schizophrenia (SZ). Gamma oscillations and their regulation by NMDA receptors can be studied via their evoked power (γEP) and phase locking (γPL) in response to auditory steady-state stimulation; these auditory steady-state responses (ASSRs) may be biomarkers for target engagement and early therapeutic effects. We previously reported that memantine, an NMDA receptor antagonist, enhanced two biomarkers of early auditory information processing: prepulse inhibition and mismatch negativity (MMN) in SZ patients and healthy subjects (HS)...
December 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
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