keyword
https://read.qxmd.com/read/38318561/knowledge-and-awareness-about-anabolic-androgenic-steroid-use-as-a-body-shape-enhancer-and-its-side-effects-among-adult-gym-participants-in-jeddah-saudi-arabia
#21
JOURNAL ARTICLE
Ibrahim Abumunaser, Emad Salawati, Sultan Albogami, Taher Alzahrani, Qusai Kabouha, Jamaan Alzahrani, Abdulmajeed Almalki, Nawaf Alzahrani
BACKGROUND: Anabolic steroids, often referred to as anabolic-androgenic steroids, are steroidal androgens that include testosterone and other naturally occurring androgens, as well as synthetic androgens that are chemically linked to testosterone and have similar actions. MATERIAL AND METHODS: A cross-sectional study was conducted to evaluate the knowledge and awareness about anabolic-androgenic steroid (AAS) use and its side effects among adult gym participants in Jeddah...
January 2024: Curēus
https://read.qxmd.com/read/38304122/causal-factors-in-childhood-and-adolescence-leading-to-anabolic-androgenic-steroid-use-a-machine-learning-approach
#22
JOURNAL ARTICLE
James I Hudson, Yaakov Hudson, Gen Kanyama, Jiana Schnabel, Kristin N Javaras, Marc J Kaufman, Harrison G Pope
BACKGROUND: Prior research has demonstrated associations between anabolic-androgenic steroid (AAS) use and features from several childhood and adolescent psychosocial domains including body image concerns, antisocial traits, and low levels of parental care. However, prior approaches have been limited by their focus on individual features and lack of consideration of the relevant causal structure. METHODS: We re-analyzed data from a previous cross-sectional cohort study of 232 male weightlifters aged 18-40, of whom 101 had used AAS...
March 2024: Drug Alcohol Depend Rep
https://read.qxmd.com/read/38292405/the-assessment-of-liver-function-test-and-fertility-hormones-in-saudi-athletes-using-anabolic-androgenic-steroids
#23
JOURNAL ARTICLE
Shatha Jambi, Ahmed Mirza, Torki Zughaibi, Haitham Khalil, Anwar Borai
BACKGROUND: A growing number of athletes are using synthetic anabolic-androgenic steroids (AAS), comprised of testosterone and other derivatives, to enhance athletic performance and muscle mass. Over the years, numerous reports elucidated the side effects of the illegal use of AAS, such as infertility, and liver disorders. The effect of AAS on the hepatic and reproductive systems in Saudi athletes has not yet been studied. Therefore, this study examined the liver function and sex hormone parameters of AAS users as compared to non-users...
February 2024: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://read.qxmd.com/read/38290417/association-of-anabolic-androgenic-steroid-use-with-perimortem-polypharmacy-antemortem-prescription-drug-use-and-utilization-of-health-care-services-a-finnish-triple-register-study-of-forensic-autopsy-cases
#24
JOURNAL ARTICLE
Paula Vauhkonen, Petteri Oura, Pirkko Kriikku, Mikko Ilari Mäyränpää, Katarina Lindroos
Anabolic androgenic steroid (AAS) use has previously been associated with complex polysubstance use that may increase morbidity and mortality among these individuals. In this study we aimed to further describe the features of perimortem polysubstance use, antemortem central nervous system (CNS) drug use and health care service utilization of AAS using males that suffer premature death. The main sample included all cases that were screened for AAS in connection with forensic autopsy between 2016-2019 and tested positive (n = 16)...
January 24, 2024: Forensic Science International
https://read.qxmd.com/read/38273101/knowledge-and-attitudes-toward-the-use-of-anabolic-androgenic-steroids-among-physical-education-university-students-a-cross-sectional-study-from-palestine
#25
JOURNAL ARTICLE
Suhaib Hattab, Bashar Saleh, Laith Qasarweh, Mahmoud Draidi, Sa'ed H Zyoud
The use of androgenic-anabolic steroids (AASs) has increased in recent years, especially among athletes, due to their effect on body shape and performance. These agents could have serious side effects on this highly susceptible population, which tends to use these substances frequently to promote muscle growth and physical performance. Therefore, this study aimed to evaluate the knowledge and attitudes toward the use of anabolic androgenic steroids among physical education university students in Palestine. A cross-sectional study of physical education students from November 2020 to January 2021 was conducted using an electronic questionnaire...
January 25, 2024: Scientific Reports
https://read.qxmd.com/read/38268076/treatment-seeking-behavior-and-cardiovascular-morbidity-among-men-with-anabolic-androgenic-steroid-use-a%C3%A2-cross-sectional-study
#26
JOURNAL ARTICLE
Hans Christian Bordado Henriksen, Ingrid Amalia Havnes, Marie Lindvik Jørstad, Rang Abdullah, Per Medbøe Thorsby, Lisa Evju Hauger, Thor Edvardsen, Kristina H Haugaa, Vibeke Marie Almaas, Astrid Bjørnebekk
AIMS: To determine associations between anabolic-androgenic steroid (AAS) use-related morbidity including cardiovascular disease (CVD) and engagement to health services. METHODS: In this cross-sectional study, 90 males with at least 12 months cumulative current or former use of AAS were included. The participants were divided into a treatment-seeking group (TSG) and a non-treatment seeking group (non-TSG) based on their responses to a self-report web questionnaire...
January 2024: Scandinavian Journal of Medicine & Science in Sports
https://read.qxmd.com/read/38254047/sleep-pathology-and-use-of-anabolic-androgen-steroids-among-male-weightlifters-in-norway
#27
JOURNAL ARTICLE
Sandra Klonteig, Morgan Scarth, Astrid Bjørnebekk
Use of anabolic androgenic steroids (AAS) causes drastic changes in hormonal milieu and is associated with a range of medical and psychological consequences. Sleep pathology is a common side-effect of AAS use but few have studied these relations. This study examined the relationship between AAS use, psychological distress and sleep quality, and how phases of heavy use and abstinence influence sleep. The Pittsburgh-Sleep-Quality-Index (PSQI) and Jenkins Sleep Scale (JSS) were used to assess sleep quality, and psychological distress was measured with the Hopkins Symptoms Checklist (HSCL)...
January 22, 2024: BMC Psychiatry
https://read.qxmd.com/read/38251285/training-pharmacological-ergogenic-aids-dehydration-and-nutrition-strategies-during-a-peak-week-in-competitive-brazilian-bodybuilders-an-observational-cross-sectional-study-in-a-non-world-anti-doping-agency-competitive-environment
#28
JOURNAL ARTICLE
Fernando Noronha de Almeida, Dahan da Cunha Nascimento, Ronaldo Ferreira Moura, Douglas Leão Peixoto, Wilson Max Almeida Monteiro de Moraes, Brad J Schoenfeld, Ivo Vieira de Sousa Neto, Jonato Prestes
BACKGROUND: this observational and cross-sectional study aimed to describe training, pharmacological ergogenic aids, dehydration, and nutrition strategies during a peak week in competitive bodybuilders and monitor changes that occurred across this period. METHODS: Ten amateur bodybuilders were followed during a peak week phase and one day post-contest. Training, diet, dehydration protocol, anabolic steroid use, and nonsteroidal agents were recorded, prescribed, and supervised by the same coach in charge...
December 29, 2023: Sports
https://read.qxmd.com/read/38234065/detection-of-methandienone-and-its-metabolites-in-equine-urine-plasma-and-hair-following-a-multidose-oral-administration
#29
JOURNAL ARTICLE
Marjaana Viljanto, Catherine Love, Daniel White, Jocelyn Habershon-Butcher, Pamela Hincks, Bobby Gray, James Scarth
Methandienone is an anabolic-androgenic steroid that is prohibited in equine sports due to its potential performance enhancing properties. Metabolism and detection of methandienone in equine urine have been investigated comprehensively in literature; however, there is a limited knowledge about its metabolites in equine plasma and no information about its detection in equine hair. Following a multi-dose oral administration of methandienone to two Thoroughbred horses, 17-epimethandienone, methyltestosterone, two mono-hydroxylated, two di-hydroxylated and three 17α-methylandrostanetriol metabolites were detected in plasma...
January 17, 2024: Drug Testing and Analysis
https://read.qxmd.com/read/38231120/liver-abnormalities-are-frequent-and-persistent-in-patients-with-fanconi-anemia
#30
JOURNAL ARTICLE
Alana J Snyder, Kathleen M Campbell, Adam Lane, Parinda A Mehta, Kasiani C Myers, Stella M Davies, Jane Koo
Liver disease has not been well-described in patients with Fanconi anemia (FA). Chronic hepatobiliary disease in patients with FA has been attributed variously to the consequences of androgen therapy, acute and late toxicities from hematopoietic stem cell transplant and hepatic tumors. Improvements in outcomes of transplant mean that more individuals with FA are reaching adulthood and new features of the FA phenotype are being discovered. We performed a retrospective review of liver function in a cohort of 97 FA patients followed for at least 10 years at a single center...
January 17, 2024: Blood Advances
https://read.qxmd.com/read/38215797/cutaneous-manifestations-of-misuse-of-androgenic-anabolic-steroids-a-retrospective-cohort-study
#31
JOURNAL ARTICLE
Ida M Heerfordt, Josefine Windfeld-Mathiasen, Kim Peder Dalhoff, Mette Mogensen, Jon Trærup Andersen, Henrik Horwitz
No abstract text is available yet for this article.
January 10, 2024: Journal of the American Academy of Dermatology
https://read.qxmd.com/read/38213269/carotid-intima-media-thickness-as-a-marker-of-increased-cardiovascular-risk-due-to-androgenic-anabolic-steroids-in-male-bodybuilders-a-cross-sectional-study
#32
JOURNAL ARTICLE
Baris Karagun
BACKGROUND: The usage of androgenic-anabolic steroids (AAS) leads to severe side effects. The aim of our study was to investigate the effects of AAS on the increase in the carotid intima-media thickness which is regarded as predictor of cardiovascular disorders and determine the association of ASS usage to urinary, hepatic, and hematological systems as well as lipid disorders. METHODS: A total of 60 male bodybuilders (30 AAS users with a mean age of 31.2±8...
January 11, 2024: Journal of Sports Medicine and Physical Fitness
https://read.qxmd.com/read/38202665/rapid-and-simultaneous-determination-of-anabolic-andro-genic-steroids-in-livestock-and-poultry-meat-using-one-step-solid-phase-extraction-coupled-with-uhplc-ms-ms
#33
JOURNAL ARTICLE
Liqun Wang, Yonghong Yan, Yan Wang, Qingqin Lv, Shuang Teng, Wei Wang
Anabolic androgenic steroids (AASs) are usually illegally added to animal feed because they can significantly promote animal growth and increase carcasses' leanness, which threatens the safety of animal-derived foods and indirectly hazards human health. This study aimed to establish an ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method for the simultaneous detection of twelve AAS residues in livestock and poultry meat. The homogenized samples were extracted with acetonitrile containing 1% acetic acid ( v / v ) and purified using the one-step extraction column...
December 22, 2023: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38181852/prolonged-testosterone-17%C3%AE-cyclopentylpropionate-exposition-induces-behavioral-ovarian-oviductal-uterine-and-reproductive-disturbances-in-female-mice
#34
JOURNAL ARTICLE
Mônica N Barcelos, Elda Gonçalves-Santos, Matheus A Souza, Eliziária C Santos, Reggiani V Gonçalves, Angel Mauricio C Gamero, Rômulo D Novaes
Anabolic-androgenic steroids (AAS) abuse is often associated with metabolic disorders and infertility. However, the current evidence on AAS-induced reproductive toxicity is mainly based on male studies. Thus, AAS repercussions on female reproductive capacity remain poorly understood, despite scarce evidence that fertility determinants may be more severely impaired in females than males exposed to these drugs. Accordingly, this study used an integrated framework to investigate the impact of different testosterone 17β-cyclopentylpropionate (TC) doses on pain sensitivity, aggressiveness, anxiety, sexual behavior, ovarian, oviductal, uterine and reproductive morphofunctional and molecular outcomes...
January 3, 2024: Life Sciences
https://read.qxmd.com/read/38176451/impact-of-anabolic-androgenic-steroids-on-covid-19
#35
REVIEW
Khaja Moinuddin Shaik, Vijay Patibandla, Sukhendu Nandi
In the wake of the Novel Coronavirus arrival, the world witnessed the fragility of healthcare systems and the resilience of healthcare workers who stood on the front lines. SARS-CoV-2, also known as COVID-19 or severe acute respiratory syndrome, first appeared in China in December 2019. The infection quickly spread across the nation and the world. All countries severely restricted social interaction to stop the virus's transmission, impacting all sporting, social, and recreational activities. Anabolic androgenic steroids (AASs) are frequently used illegally to enhance strength and physical attractiveness...
January 2, 2024: Steroids
https://read.qxmd.com/read/38128896/purinergic-signaling-influences-the-neuroinflammatory-outcomes-of-a-testosterone-derived-synthetic-in-female-rats-resistance-training-protective-effects-on-brain-health
#36
JOURNAL ARTICLE
Aline da Silva Pereira, Nathieli Bianchin Bottari, Jelson Norberto Nauderer, Charles Elias Assmann, Priscila Marquezan Copetti, Karine Paula Reichert, Vitor Bastianello Mostardeiro, Marcylene Vieira da Silveira, Vera Maria Melchiors Morsch, Maria Rosa Chitolina Schetinger
Physical exercise is recognized as a non-pharmacological approach against several neuroinflammatory conditions and thus prevent brain disorders. However, the search for ergogenic resources by athletes in the sports field and by bodybuilding practitioners in gyms has been increasingly common and on the rise. This practice shortens the process of performance gain and improves aesthetics, having led to the prominent use and abuse of hormones in the past years. Recent evidence has pointed out that the purinergic system, composed of adenine nucleotides, nucleosides, enzymes, and receptors, largely participates in a wide range of functions within the brain, such as neuroinflammation, neuromodulation, and cellular communication...
December 19, 2023: Steroids
https://read.qxmd.com/read/38102386/factors-predicting-normalization-of-reproductive-hormones-after-cessation-of-anabolic-androgenic-steroids-in-men-a-single-center-retrospective-study
#37
JOURNAL ARTICLE
Bonnie Grant, John Campbell, Anjali Pradeep, Angela D Burns, Paul Bassett, Ali Abbara, Priyadarshi Saket, Sukhbinder Minhas, Waljit S Dhillo, James McVeigh, Shalender Bhasin, Channa N Jayasena
OBJECTIVE: Symptomatic hypogonadism discourages men from stopping anabolic-androgenic steroids (AAS). Some men illicitly take drugs temporarily stimulating endogenous testosterone following AAS cessation (post-cycle therapy; PCT) to lessen hypogonadal symptoms. We investigated whether prior PCT use was associated with the normalization of reproductive hormones following AAS cessation. METHODS: Retrospective analysis of 641 men attending a clinic between 2015-2022 for a single, nonfasting, random blood test <36 months following AAS cessation, with or without PCT...
December 6, 2023: European Journal of Endocrinology
https://read.qxmd.com/read/38092130/biotransformation-of-anabolic-androgenic-steroids-in-human-skin-cells
#38
JOURNAL ARTICLE
Lingyu Liu, Ziaul Karim, Nils Schlörer, Xavier de la Torre, Francesco Botrè, Christian Zoschke, Maria Kristina Parr
In comparison to well-known drug-metabolizing organs such as the liver, the metabolic capacity of human skin is still not well elucidated despite the widespread use of topical drug application. To gain a comprehensive insight into anabolic steroid metabolism in the skin, six structurally related anabolic androgenic steroids, testosterone, metandienone, methyltestosterone, clostebol, dehydrochloromethyltestosterone, and methylclostebol, were applied to human keratinocytes and fibroblasts derived from the juvenile foreskin...
December 11, 2023: Journal of Steroid Biochemistry and Molecular Biology
https://read.qxmd.com/read/38085771/lived-experiences-of-closeness-to-a-person-using-anabolic-androgenic-steroids-a-next-of-kin-perspective
#39
JOURNAL ARTICLE
Annica Börjesson, Margaretha Ekebergh, Marja-Liisa Dahl, Lena Ekström, Mikael Lehtihet, Veronica Vicente
PURPOSE: Anabolic androgenic steroids (AAS) are used for their aesthetic and performance-enhancing effects and are associated with physical and psychological side effects. Behavioural changes/side effects as mood swings, aggressiveness, depression, potency problems, anxiety, and emotional coldness have been reported by next of kin to people using AAS. METHODS: This phenomenological study is based on the reflective lifeworld research approach. Interviews were conducted with twelve next of kin about their experiences of living close to persons using AAS...
December 2024: International Journal of Qualitative Studies on Health and Well-being
https://read.qxmd.com/read/38085110/trace-analysis-of-5-androgens-in-environmental-waters-by-optimization-of-enzymolysis-and-solid-phase-extraction-ultra-performance-liquid-chromatography-mass-spectrometry-and-its-risk-assessment
#40
JOURNAL ARTICLE
Yufei Xie, Zhihan Gao, Yuan Ren
Steroid hormones (SHs), have received widespread attention in recent years. However, current studies of SHs have primarily focused on estrogenic substances and androgen-related studies are still very limited. In this study, the solid-phase extraction (SPE) pre-treatment method, as well as the enzymolysis conditions of 5 androgenic materials, such as Androstenedione, Boldenone, Methandienone, Nandrolone, and Testosterone, were optimized to simultaneously determine their concentrations in the effluent from wastewater treatment plants (WWTP) and surface water samples...
December 12, 2023: Environmental Toxicology and Chemistry
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