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https://www.readbyqxmd.com/read/28631113/fast-determination-of-ingredients-in-solid-pharmaceuticals-by-microwave-enhanced-in-source-decay-of-microwave-plasma-torch-mass-spectrometry
#1
Rui Su, Xinchen Wang, Changming Hou, Meiling Yang, Keke Huang, Huanwen Chen
Rapid qualitative and quantitative analysis of solid samples (e.g., pharmaceutical preparations) by using a small and low-resolution mass spectrometer without MS/MS function is still a challenge in ambient pressure ionization mass spectrometric analysis. Herein, a practically efficient method termed microwave-enhanced in-source decay (MEISD) using microwave plasma torch desorption ionization coupled with time-of-flight mass spectrometry (MPTDI-TOF MS) was developed for fast analysis of pharmaceutical tablets using a miniature TOF mass spectrometer without tandem mass function...
June 19, 2017: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/28628730/comparative-study-on-ambient-ionization-methods-for-direct-analysis-of-navel-orange-tissues-by-mass-spectrometry
#2
H Zhang, A Bibi, H Lu, J Han, H Chen
It is of sustainable interest to improve the sensitivity and selectivity of the ionization process, especially for direct analysis of complex samples without matrix separation. Herein, four ambient ionization methods including desorption atmospheric pressure chemical ionization (DAPCI), heat-assisted desorption atmospheric pressure chemical ionization (heat-assisted DAPCI), microwave plasma torch (MPT), and internal extractive electrospray ionization (iEESI) were employed for comparative analysis of the navel orange tissue samples by mass spectrometry...
June 19, 2017: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/28622418/severe-apparently-isolated-fetal-ventriculomegaly-and-neurodevelopmental-outcome
#3
Mathilde Letouzey, Alexandra Chadie, Marie Brasseur-Daudruy, François Proust, Eric Verspyck, Pascal Boileau, Stéphane Marret
OBJECTIVE: To assess the neurodevelopmental outcome of children with a prenatal diagnosis of apparently isolated severe ventriculomegaly (SVM). METHOD: Retrospective cohort study from 1994 to 2011. We included fetuses with unilateral or bilateral ventriculomegaly equal to or greater than 15 mm at prenatal ultrasound and confirmed by Magnetic Resonance Imaging, whose parents chose continuation of pregnancy past 22 weeks, and with no associated findings at diagnosis (i...
June 16, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28604289/a-suitable-soil-plague-s-urban-breeding-grounds-at-the-dawn-of-the-third-pandemic
#4
Christos Lynteris
A pressing question during the first half-decade of the third plague pandemic (1894-9) was what was a 'suitable soil' for the disease. The question related to plague's perceived ability to disappear from a given city only to reappear at some future point; a phenomenon that became central to scientific investigations of the disease. However, rather than this simply having a metaphorical meaning, the debate around plague's 'suitable soil' actually concerned the material reality of the soil itself. The prevalence of plague in the working-class neighbourhood of Taipingshan during the first major outbreak of the pandemic, in 1894 in Hong Kong, led to an extensive debate regarding the ability of the soil to harbour and even spread the disease...
July 2017: Medical History
https://www.readbyqxmd.com/read/28585522/structural-and-photoluminescence-properties-of-silicon-nanowires-extracted-by-means-of-a-centrifugation-process-from-plasma-torch-synthesized-silicon-nanopowder
#5
Vincent Le Borgne, Marta Agati, Simona Boninelli, Paola Castrucci, Maurizio De Crescenzi, Richard Dolbec, My Ali El Khakani
We report on a method for the extraction of silicon nanowires (SiNWs) from the by-product of a plasma torch based spheroidization process of silicon. This by-product is a nanopowder which consists of a mixture of SiNWs and silicon particles. By optimizing a centrifugation based process, we were able to extract substantial amounts of highly pure Si nanomaterials (mainly SiNWs and Si nanospheres (SiNSs)). While the purified SiNWs were found to have typical outer diameters in the 10-15 nm range and lengths of up to several µm, the SiNSs have external diameters in the 10-100 nm range...
June 6, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28579764/is-zika-virus-an-emerging-torch-agent-an-invited-commentary
#6
Mohammad Zare Mehrjardi
Zika virus (ZIKV) is a mosquito-borne arbovirus from the family Flaviviridae, which had caused some epidemics since its discovery in 1947 without any significant impacts on public health. In 2015, however, a 20-fold increase in congenital microcephaly cases in northeastern Brazil was attributed to prenatally acquired ZIKV infection. Traditionally, TORCH agents have 4 common characteristics including causing a mild illness in infected mother, vertical transmission to fetus, developing several anomalies in the affected fetus, and in some instances, maternal therapy may not ameliorate fetal prognosis...
2017: Virology: Research and Treatment
https://www.readbyqxmd.com/read/28573989/evaluation-of-kayser-fleischer-ring-in-wilson-disease-by-anterior-segment-optical-coherence-tomography
#7
Mittanamalli S Sridhar, Advithi Rangaraju, Kavitha Anbarasu, Sharat Putta Reddy, Sachin Daga, Sita Jayalakshmi, Bajibhi Shaik
PURPOSE: The purpose of the study is to present anterior segment optical coherence tomography (AS-OCT) as an alternative method of evaluating Kayser-Fleischer (KF) ring in Wilson disease (WD) not only by ophthalmologists but also by other clinicians dealing with WD. MATERIALS AND METHODS: This was a retrospective case series of six WD patients with KF ring. Evaluation of KF ring was done by naked eye examination using torch light, slit lamp biomicroscopy (SL), and AS-OCT...
May 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28550383/-you-can-carry-the-torch-now-a-qualitative-analysis-of-parents-experiences-caring-for-a-child-with-trisomy-13-or-18
#8
Joshua D Arthur, Divya Gupta
Trisomy 13 and 18 (T 13/18) are rare chromosomal abnormalities associated with high morbidity and mortality. Improved survival rates and increased prevalence of aggressive medical intervention have resulted in families and physicians holding different perspectives regarding the appropriate management of children with T 13/18. Families were invited for open-ended interviews regarding their experiences with the medical care of a child with T 13/18 over the past 5 years. Seven of 33 invited families were surveyed; those who had spent more than 40 days in the hospital were most likely to accept the invitation (OR 8...
May 26, 2017: HEC Forum: An Interdisciplinary Journal on Hospitals' Ethical and Legal Issues
https://www.readbyqxmd.com/read/28540600/microglial-interferon-signaling-and-white-matter
#9
Ashley McDonough, Richard V Lee, Jonathan R Weinstein
Microglia, the resident immune cells of the CNS, are primary regulators of the neuroimmune response to injury. Type I interferons (IFNs), including the IFNαs and IFNβ, are key cytokines in the innate immune system. Their activity is implicated in the regulation of microglial function both during development and in response to neuroinflammation, ischemia, and neurodegeneration. Data from numerous studies in multiple sclerosis (MS) and stroke suggest that type I IFNs can modulate the microglial phenotype, influence the overall neuroimmune milieu, regulate phagocytosis, and affect blood-brain barrier integrity...
May 25, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28515947/the-impact-of-body-armor-on-physical-performance-of-law-enforcement-personnel-a-systematic-review
#10
Colin Tomes, Robin Marc Orr, Rodney Pope
BACKGROUND: The law enforcement officer profession requires performance of arduous occupational tasks while carrying an external load, consisting of, at minimum, a chest rig, a communication system, weaponry, handcuffs, personal protective equipment and a torch. The aim of this systematic review of the literature was to identify and critically appraise the methodological quality of published studies that have investigated the impacts of body armour on task performance and to synthesize and report key findings from these studies to inform law enforcement organizations...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28492481/a-vision-aided-3d-path-teaching-method-before-narrow-butt-joint-welding
#11
Jinle Zeng, Baohua Chang, Dong Du, Guodong Peng, Shuhe Chang, Yuxiang Hong, Li Wang, Jiguo Shan
For better welding quality, accurate path teaching for actuators must be achieved before welding. Due to machining errors, assembly errors, deformations, etc., the actual groove position may be different from the predetermined path. Therefore, it is significant to recognize the actual groove position using machine vision methods and perform an accurate path teaching process. However, during the teaching process of a narrow butt joint, the existing machine vision methods may fail because of poor adaptability, low resolution, and lack of 3D information...
May 11, 2017: Sensors
https://www.readbyqxmd.com/read/28484817/pen-torch-transillumination-difficult-venepuncture-made-easy
#12
Elijah Zhengyang Cai, Kalarani Sankaran, Monica Tan, Yiong Huak Chan, Thiam Chye Lim
INTRODUCTION: Our novel technique of pen torch transillumination (PTI) uses a cheap and easily available instrument (Penlite-LP212(®), Energizer(®), Missouri, USA) to visualize superficial veins invisible to the naked eye. We evaluate the efficacy of PTI in improving venepuncture success rate (SR) for patients with poor venous access. METHODS: This prospective randomized controlled trial looked at adult patients (n = 69) aged 21-90 with difficult venous access (history of ≥3 consecutive attempts required for successful cannulation during the current admission) requiring non-emergent venepuncture...
May 8, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28462606/perinatal-outcome-in-pregnancy-with-polyhydramnios-in-comparison-with-normal-pregnancy-in-department-of-obstetrics-at-shiraz-university-of-medical-sciences
#13
Nasrin Asadi, Azadeh Khalili, Zahra Zarei, Arsalan Azimi, Maryam Kasraeian, Leila Forouginia, Ali Reza Salehi, Reza Ravanbod, Sarah Davoodi, Homeira Vafaei
OBJECTIVE: Polyhydraminos can lead to maternal and fetal complication during pregnancy, so diagnosis and management can decrease some perinatal complications. STUDY DESIGN: 114 singleton pregnancies were diagnosed with idiopathic polyhydramnios in the department of obstetrics at Shiraz University of Medical Sciencesbetween January 2000 and January 2011 were compared with 114 normal pregnancies for their perinatal outcome. Variables include birth weight, admission toneonatal intensive care unit (NICU), meconium staining, respiratory distress, fetal death,neonatal death,low 1 minute and 5minute APGAR score, primary cesarean section(C/S), preterm delivery (<37 weeks),postpartum bleeding and placental abruption...
May 2, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28427160/biomarker-analysis-of-the-phase-3-torch-trial-for-first-line-erlotinib-versus-chemotherapy-in-advanced-non-small-cell-lung-cancer-patients
#14
Lucia Kim, Mauro Saieg, Massimo Di Maio, Ciro Gallo, Charles Butts, Fortunato Ciardiello, Ronald Feld, Dengxiao Cheng, Vittorio Gebbia, Marco Angelo Burgio, Yasmin Alam, Simona Signoriello, Antonio Rossi, Natasha Leighl, Paolo Maione, Alessandro Morabito, Geoffrey Liu, Ming-Sound Tsao, Francesco Perrone, Cesare Gridelli
BACKGROUND: The TORCH phase III trial compared the efficacy of first-line erlotinib followed by chemotherapy at progression (experimental arm) with the reverse sequence (standard arm) in unselected advanced non-small cell lung cancer (NSCLC) patients. Here we report biomarker analyses. METHODS: EGFR and KRAS mutation, expression of EGFR family members and of cMET and PTEN and EGFR and ABCG2 germline polymorphisms were tested on tumor tissue or blood samples to either confirm previously proposed predictive role or describe it in an explorative setting...
February 25, 2017: Oncotarget
https://www.readbyqxmd.com/read/28373641/influence-of-nitric-oxide-generated-through-microwave-plasma-on-l6-skeletal-muscle-cell-myogenesis-via-oxidative-signaling-pathways
#15
Naresh Kumar, Priyanka Shaw, Han Sup Uhm, Eun Ha Choi, Pankaj Attri
Myogenic precursors are myoblasts that have a potency to differentiate into muscle fibers on injury and maintain the regenerative power of skeletal muscle. However, the roles of exogenous nitric oxide (NO) in muscle development and myoblast differentiation are largely unknown. Therefore, in this study, we examined the effects of exogenous NO generated by a microwave plasma torch on rat myoblastic L6 cell proliferation and differentiation. We observed that the differentiation of L6 myogenic precursor cells into myotubes was significantly enhanced after NO treatment...
April 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28358813/prevalence-and-associated-factors-of-pterygium-among-adults-living-in-gondar-city-northwest-ethiopia
#16
Dereje Hayilu Anbesse, Tsehay Kassa, Biruktayit Kefyalew, Atirsaw Tasew, Abie Atnie, Beredu Desta
PURPOSE: The aim of this study was to assess the prevalence and associated factors of pterygium among adults living in Gondar city, Northwest Ethiopia. METHODS: A cross sectional design study was carried out in 390 participants in Gondar city from April 15 to May 7, 2016. Basic ophthalmic examination was performed using portable slit lamb, 3.5x magnifying loop with torch light and a pretested and structured questionnaire was completed. The raw data has been entered into EPI INFO 3...
2017: PloS One
https://www.readbyqxmd.com/read/28335425/linear-mathematical-model-for-seam-tracking-with-an-arc-sensor-in-p-gmaw-processes
#17
Wenji Liu, Liangyu Li, Ying Hong, Jianfeng Yue
Arc sensors have been used in seam tracking and widely studied since the 80s and commercial arc sensing products for T and V shaped grooves have been developed. However, it is difficult to use these arc sensors in narrow gap welding because the arc stability and sensing accuracy are not satisfactory. Pulse gas melting arc welding (P-GMAW) has been successfully applied in narrow gap welding and all position welding processes, so it is worthwhile to research P-GMAW arc sensing technology. In this paper, we derived a linear mathematical P-GMAW model for arc sensing, and the assumptions for the model are verified through experiments and finite element methods...
March 14, 2017: Sensors
https://www.readbyqxmd.com/read/28335222/effects-of-atomization-injection-on-nanoparticle-processing-in-suspension-plasma-spray
#18
Hong-Bing Xiong, Cheng-Yu Zhang, Kai Zhang, Xue-Ming Shao
Liquid atomization is applied in nanostructure dense coating technology to inject suspended nano-size powder materials into a suspension plasma spray (SPS) torch. This paper presents the effects of the atomization parameters on the nanoparticle processing. A numerical model was developed to simulate the dynamic behaviors of the suspension droplets, the solid nanoparticles or agglomerates, as well as the interactions between them and the plasma gas. The plasma gas was calculated as compressible, multi-component, turbulent jet flow in Eulerian scheme...
May 20, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28296971/retention-and-sustainability-of-community-based-health-volunteers-activities-a-qualitative-study-in-rural-northern-ghana
#19
Samuel Chatio, Patricia Akweongo
BACKGROUND: The shortage of formal health workers has led to the utilization of Community-Based Health Volunteers (CBHV) to provide health care services to people especially in rural and neglected communities. Community-based health volunteers have been effective partners in health care delivery at the community level for many years. The challenge is how to retain these volunteers and also sustain their activities. This study explored factors affecting retention and sustainability of community-based health volunteers' activities in a rural setting in Northern Ghana...
2017: PloS One
https://www.readbyqxmd.com/read/28292484/external-validation-of-health-economic-decision-models-for-chronic-obstructive-pulmonary-disease-copd-report-of-the-third-copd-modeling-meeting
#20
Martine Hoogendoorn, Talitha L Feenstra, Yumi Asukai, Andrew H Briggs, Ryan N Hansen, Reiner Leidl, Nancy Risebrough, Yevgeniy Samyshkin, Margarethe Wacker, Maureen P M H Rutten-van Mölken
OBJECTIVES: To validate outcomes of presently available chronic obstructive pulmonary disease (COPD) cost-effectiveness models against results of two large COPD trials-the 3-year TOwards a Revolution in COPD Health (TORCH) trial and the 4-year Understanding Potential Long-term Impacts on Function with Tiotropium (UPLIFT) trial. METHODS: Participating COPD modeling groups simulated the outcomes for the placebo-treated groups of the TORCH and UPLIFT trials using baseline characteristics of the trial populations as input...
March 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
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