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https://www.readbyqxmd.com/read/29912857/stretch-could-reduce-hamstring-injury-risk-during-sprinting-by-right-shifting-the-length-torque-curve
#1
Mianfang Ruan, Li Li, Chen Chen, Xie Wu
Ruan, M, Li, L, Chen, C, and Wu, X. Stretch could reduce hamstring injury risk during sprinting by right shifting the length-torque curve. J Strength Cond Res XX(X): 000-000, 2018-It was hypothesized that static stretch would shift the length-torque curve to the right, which may reduce the risk of muscle strain injuries. The purpose of this study was to evaluate the acute effects of static stretching of hamstring (SSH) on the risk of hamstring injury during sprinting indicated by the shift of the length-torque relationship...
June 15, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29754415/biological-hydropersulfides-and-related-polysulfides-a-new-concept-and-perspective-in-redox-biology
#2
REVIEW
Jon M Fukuto, Louis J Ignarro, Peter Nagy, David A Wink, Christopher G Kevil, Martin Feelisch, Miriam M Cortese-Krott, Christopher L Bianco, Yoshito Kumagai, Adrian J Hobbs, Joseph Lin, Tomoaki Ida, Takaaki Akaike
The chemical biology of thiols (RSH, e.g., cysteine and cysteine containing proteins/peptides) has been a topic of extreme interest for many decades due to their reported roles in protein structure/folding, redox signaling, metal ligation, cellular protection and enzymology. While many of the studies on thiol/sulfur biochemistry have focused on thiols, relatively ignored have been hydropersulfides (RSSH) and higher order polysulfur species (RSSn H, RSSn R, n > 1). Recent and provocative work has alluded to the prevalence and likely physiological importance of RSSH and related RSSn H...
May 12, 2018: FEBS Letters
https://www.readbyqxmd.com/read/29753984/a-novel-white-spot-syndrome-virus-protein-wssv164-controls-prophenoloxidases-pmpropos-in-shrimp-melanization-cascade
#3
Pakkakul Sangsuriya, Walaiporn Charoensapsri, Jantiwan Sutthangkul, Saengchan Senapin, Ikuo Hirono, Anchalee Tassanakajon, Piti Amparyup
Melanization, mediated by the prophenoloxidase (proPO)-activating system, is an important innate immune response in invertebrates. The implication of the proPO system in antiviral response and the suppression of host proPO activation by the viral protein have previously been demonstrated in shrimp. However, the molecular mechanism of viral-host interactions in the proPO cascade remains largely unexplored. Here, we characterized the viral protein, namely, WSSV164, which was initially identified from the forward suppression subtractive hybridization (SSH) cDNA library of the PmproPO1/2 co-silenced black tiger shrimp Penaeus monodon that was challenged with white spot syndrome virus (WSSV)...
May 4, 2018: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/29751742/integrated-mirna-mrna-analysis-reveals-regulatory-pathways-underlying-the-curly-fleece-trait-in-chinese-tan-sheep
#4
Yufang Liu, Jibin Zhang, Qiao Xu, Xiaolong Kang, Kejun Wang, Keliang Wu, Meiying Fang
BACKGROUND: Tan sheep is an indigenous Chinese breed well known for its beautiful curly fleece. One prominent breed characteristic of this sheep breed is that the degree of curliness differs markedly between lambs and adults, but the molecular mechanisms regulating the shift are still not well understood. In this study, we identified 49 differentially expressed (DE) microRNAs (miRNAs) between Tan sheep at the two stages through miRNA-seq, and combined the data with that in our earlier Suppression Subtractive Hybridization cDNA (SSH) library study to elucidate the mechanisms underlying curly fleece formation...
May 11, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29715682/comparative-transcriptomic-analysis-of-the-roots-of-intercropped-peanut-and-maize-reveals-novel-insights-into-peanut-iron-nutrition
#5
Jing Dai, Wei Qiu, Nanqi Wang, Hiromi Nakanishi, Yuanmei Zuo
Intercropping is a vital technology in resource-limited agricultural systems with low inputs. Peanut/maize intercropping enhances iron (Fe) nutrition in calcareous soil. In this study, the transcriptome of peanut and maize roots was analyzed by suppression subtractive hybridization (SSH) and microarray analysis separately. We constructed four SSH libraries using the cDNA of peanut roots based on two cropping patterns: monocropping and intercropping, and two growth stages: vegetative stage and reproductive stage...
April 23, 2018: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29714727/edge-modes-of-scattering-chains-with-aperiodic-order
#6
Ren Wang, Malte Röntgen, Christian V Morfonios, Felipe A Pinheiro, Peter Schmelcher, Luca Dal Negro
We study the scattering resonances of one-dimensional deterministic aperiodic chains of electric dipoles using the vectorial Green's matrix method, which accounts for both short- and long-range electromagnetic interactions in open scattering systems. We discover the existence of edge-localized scattering states within fractal energy gaps with characteristic topological band structures. Notably, we report and characterize edge-localized modes in the classical wave analogues of the Su-Schrieffer-Heeger (SSH) dimer model, quasiperiodic Harper and Fibonacci crystals, as well as in more complex Thue-Morse aperiodic systems...
May 1, 2018: Optics Letters
https://www.readbyqxmd.com/read/29706803/why-are-social-sciences-and-humanities-needed-in-the-works-of-ipbes-a-systematic-review-of-the-literature
#7
Alice B M Vadrot, Aleksandar Rankovic, Renaud Lapeyre, Pierre-Marie Aubert, Yann Laurans
Despite the increased attention, which has been given to the issue of involving knowledge and experts from the social sciences and humanities (SSH) into the products and works of the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES), little is known on what the expectations towards the involvement of SSH in IPBES actually are. The aim of this paper is to close this gap by identifying the range of possible SSH contributions to IPBES that are expected in the literature, and discuss the inherent challenges of and concrete ways to realize these contributions in the particular institutional setting of IPBES...
2018: Innovation: the European Journal of Social Sciences
https://www.readbyqxmd.com/read/29656400/pkd-regulates-actin-polymerization-neutrophil-deformability-and-transendothelial-migration-in-response-to-fmlp-and-trauma
#8
Christoph Wille, Tim Eiseler, Sven-Thorben Langenberger, Julia Richter, Kensaku Mizuno, Peter Radermacher, Uwe Knippschild, Markus Huber-Lang, Thomas Seufferlein, Stephan Paschke
Neutrophils are important mediators of the innate immune defense and of the host response to a physical trauma. Because aberrant infiltration of injured sites by neutrophils was shown to cause adverse effects after trauma, we investigated how neutrophil infiltration could be modulated at the cellular level. Our data indicate that protein kinase D (PKD) is a vital regulator of neutrophil transmigration. PKD phosphorylates the Cofilin-phosphatase Slingshot-2L (SSH-2L). SSH-2L in turn dynamically regulates Cofilin activity and actin polymerization in response to a chemotactic stimulus for neutrophils, for example, fMLP...
April 14, 2018: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/29579043/experiments-in-interdisciplinarity-responsible-research-and-innovation-and-the-public-good
#9
Ana Delgado, Heidrun Åm
In Europe, responsible research and innovation (RRI) has emerged as a science policy measure that demands the early integration of a broad range of social actors and perspectives into research and development (R&D). More collaboration of the social sciences and humanities (SSH) with science and engineering appears within this policy framework as a crucial element that will enable better technological development. However, RRI is new to both natural scientists and SSH scholars, and interdisciplinary collaborations are challenging for many reasons...
March 2018: PLoS Biology
https://www.readbyqxmd.com/read/29551678/hemocyanin-of-litopenaeus-vannamei-agglutinates-vibrio-parahaemolyticus-ahpnd-vp-ahpnd-and-neutralizes-its-toxin
#10
Pakpoom Boonchuen, Phattarunda Jaree, Anchalee Tassanakajon, Kunlaya Somboonwiwat
Acute hepatopancreatic necrosis disease, AHPND, caused by a specific strain of Vibrio parahaemolyticus (VPAHPND ), results in great loss of global shrimp production. Despite this, studies on shrimp defense mechanisms protecting against AHPND are few. In this study, suppression subtractive hybridization (SSH) was performed to identify differentially expressed genes from white shrimp Litopenaeus vannamei hepatopancreas upon VPAHPND infection at the early stages: 3 and 6 h post challenge and in the late stage at 48 h post challenge...
July 2018: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/29537884/current-status-of-sperm-functional-genomics-and-its-diagnostic-potential-of-fertility-in-bovine-bos-taurus
#11
Sellappan Selvaraju, Sivashanmugam Parthipan, Lakshminarayana Somashekar, B Krishnan Binsila, Atul P Kolte, Arunachalam Arangasamy, Janivara Parameshwaraiah Ravindra, Stephen A Krawetz
With artificial insemination (AI) and other precision dependent assisted reproductive technologies (ART) being followed in large scale in human and animal reproduction, assessing semen quality and fertilizability is under continuous scrutiny. Various tests have been developed to predict semen quality, but so far no single, highly reliable test is available. In this regard, transcriptomic profiling of spermatozoa assumes significance as it carries the information about spermatogenesis, sperm function, and paternal roles in post-fertilization events...
March 14, 2018: Systems Biology in Reproductive Medicine
https://www.readbyqxmd.com/read/29510742/molecular-and-biochemical-responses-in-the-midgut-of-the-silkworm-bombyx-mori-infected-with-nosema-bombycis
#12
Zhi Li, Yu Wang, Linling Wang, Zeyang Zhou
BACKGROUND: Microsporidia are a group of eukaryotic intracellular parasites that infect almost all vertebrates and invertebrates. However, there is little information available of how microsporidia obtain nutrients and energy from host cells. The purpose of this study was to investigate the energy and material requirements of Nosema bombycis for the invasion procedure through analyzing the global variation of the gene expression, protein abundance, fatty acids level and ATP flux induced by the microsporidia N...
March 6, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29438454/comparative-efficacy-of-antihypertensive-agents-in-salt-sensitive-hypertensive-patients-a-network-meta-analysis
#13
Han Qi, Zheng Liu, Han Cao, Wei-Ping Sun, Wen-Juan Peng, Bin Liu, Sheng-Jie Dong, Yu-Tao Xiang, Ling Zhang
Background: Salt-sensitive hypertension (SSH) is an intermediate inherited phenotype of essential hypertension as well as being an independent risk factor for cardiovascular disease. However, effective medications for the treatment of SSH have not been clarified. This study was to compare the efficacious of different classes of antihypertensive agents combined with salt intake on the reduction of blood pressure in patients with salt-sensitive hypertension (SSH). Methods: We used sources as PubMed, EMBASE, Cochrane Library, CENTRAL, ClinicalTrials...
February 9, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/29431773/a-near-infrared-fluorescent-probe-for-sensitive-detection-and-imaging-of-sulfane-sulfur-in-living-cells-and-in-vivo
#14
Xiaoyue Han, Xinyu Song, Bowei Li, Fabiao Yu, Lingxin Chen
Sulfane sulfur refers to ionized sulfur that is reversibly attached to other sulfur atoms in the form of 6-valence electrons (S0 ). Sulfane sulfur possesses stronger nucleophilicity and reducibility than hydrogen sulfide in a series of physiological reactions, which probably makes sulfane sulfur the actual signal molecule in cells. Herein, we designed and synthesized a near-infrared (NIR) fluorescent probe BD-diSH for sensitive detection and imaging of sulfane sulfur in living cells and in vivo. The probe BD-diSH is composed of two moieties: the fluorophore azo-BODIPY and the sulfane sulfur recognition unit, viz...
February 27, 2018: Biomaterials Science
https://www.readbyqxmd.com/read/29417346/transcript-profiling-and-gene-expression-analysis-under-drought-stress-in-ziziphus-nummularia-burm-f-wright-arn
#15
Radha Yadav, Om Prakash Verma, Jasdeep Chatrath Padaria
Drought is one of the prime abiotic stresses responsible for limiting agricultural productivity. A number of drought responsive genes have been isolated and functionally characterized but these studies have been restricted to a few model plant systems. Very few drought responsive genes have been reported till date from non model drought tolerant plants. The present study aimed at identifying differentially expressed genes from a drought tolerant, non-model plant, Ziziphus nummularia (Burm.f.) Wight & Arn...
April 2018: Molecular Biology Reports
https://www.readbyqxmd.com/read/29401820/robust-manipulation-of-light-using-topologically-protected-plasmonic-modes
#16
Chenxu Liu, M V Gurudev Dutt, David Pekker
We propose using a topological plasmonic crystal structure composed of an array of nearly parallel nanowires with unequal spacing for manipulating light. In the paraxial approximation, the Helmholtz equation that describes the propagation of light along the nanowires maps onto the Schrödinger equation of the Su-Schrieffer-Heeger (SSH) model. Using a full three-dimensional finite difference time domain solution of the Maxwell equations, we verify the existence of topological defect modes, with sub-wavelength localization, bound to domain walls of the plasmonic crystal...
February 5, 2018: Optics Express
https://www.readbyqxmd.com/read/29394254/differential-expression-of-genes-identified-by-suppression-subtractive-hybridization-in-liver-and-adipose-tissue-of-gerbils-with-diabetes
#17
Jingjing Gong, Xiaoyan Du, Zhenkun Li, Xiaohong Li, Meng Guo, Jing Lu, Ying Wang, Zhenwen Chen, Changlong Li
OBJECTIVES: We aimed at identifying genes related to hereditary type 2 diabetes expressed in the liver and the adipose tissue of spontaneous diabetic gerbils using suppression subtractive hybridization (SSH) screening. METHODS: Two gerbil littermates, one with high and the other with normal blood glucose level, from our previously bred spontaneous diabetic gerbil strain were used in this study. To identify differentially expressed genes in the liver and the adipose tissue, mRNA from these tissues was extracted and SSH libraries were constructed for screening...
2018: PloS One
https://www.readbyqxmd.com/read/29375807/from-population-connectivity-to-the-art-of-striping-russian-dolls-the-lessons-from-pocillopora-corals
#18
Pauline Gélin, Cécile Fauvelot, Lionel Bigot, Joseph Baly, Hélène Magalon
Here, we examined the genetic variability in the coral genus Pocillopora , in particular within the Primary Species Hypothesis PSH09, identified by Gélin, Postaire, Fauvelot and Magalon (2017) using species delimitation methods [also named Pocillopora eydouxi/meandrina complex sensu , Schmidt-Roach, Miller, Lundgren, & Andreakis (2014)] and which was found to split into three secondary species hypotheses (SSH09a, SSH09b, and SSH09c) according to assignment tests using multi-locus genotypes (13 microsatellites)...
January 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29352327/limk-cofilin-pathway-and-slingshot-are-implicated-in-human-colorectal-cancer-progression-and-chemoresistance
#19
Helen Aggelou, Panagiota Chadla, Sofia Nikou, Sofia Karteri, Ioannis Maroulis, Haralabos P Kalofonos, Helen Papadaki, Vasiliki Bravou
Cofilin phospho-regulation is important for actin filament turnover and is implicated in cancer. Phosphorylation of cofilin is mediated by LIM kinases (LIMKs) and dephosphorylation by Slingshot phosphatases (SSH). LIMKs and SSH promote cancer cell invasion and metastasis and represent novel anti-cancer targets. However, little is known regarding LIMK/cofilin and SSH in human colorectal cancer (CRC). In this study, we aimed to address their expression and significance in human CRC. We evaluated expression of non-phosphorylated (active) and phosphorylated cofilin, LIMK1, LIMK2, and SSH1 by immunohistochemistry in 143 human CRC samples in relation to clinicopathologic parameters, response of metastatic disease to chemotherapy, and epithelial-mesenchymal transition (EMT) markers β-catenin, E-cadherin, and ZEB...
January 19, 2018: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/29327094/association-between-secondhand-smoke-exposure-and-quality-of-life-in-pregnant-women-and-postpartum-women-and-the-consequences-on-the-newborns
#20
Rasmon Kalayasiri, Waranya Supcharoen, Pichanan Ouiyanukoon
PURPOSE: Secondhand smoke (SHS) exposure is prevalent and could damage the health of non-smokers, especially that of pregnant women (PW) and postpartum women (PPW). Nevertheless, there is no study on the impact of SHS during pregnancy on the quality of life (QOL) of PW and PPW. The study's purpose is to study the effects of exposure to SHS on the QOL of pregnant and postpartum women and health of the newborns. METHODS: Self-reports and urine tests for cotinine were used to obtain data on SSH exposure in 296 women in the second trimester of pregnancy and 106 women in the postpartum period at the Obstetrics & Gynecology Clinic located in a university hospital...
April 2018: Quality of Life Research
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