Yoichi Nakayama, Ryu Watanabe, Wataru Yamamoto, Kosuke Ebina, Toru Hirano, Takuya Kotani, Hideyuki Shiba, Masaki Katayama, Yonsu Son, Hideki Amuro, Akira Onishi, Sadao Jinno, Ryota Hara, Kosaku Murakami, Koichi Murata, Hiromu Ito, Masao Tanaka, Shuichi Matsuda, Akio Morinobu, Motomu Hashimoto
OBJECTIVES: Anaemia, a common comorbidity of rheumatoid arthritis (RA), is related to high disease activity and poor prognosis. It is unknown which b/ts-DMARDs are optimal for patients with anaemia and RA in regulating anaemia and controlling disease activity. METHODS: We investigated the change in haemoglobin levels, drug retention rates and disease activities after the administration of b/ts-DMARDs with different modes of action [tumour necrosis factor inhibitors (TNFi), immunoglobulin fused with cytotoxic T-lymphocyte antigen (CTLA-4-Ig), interleukin-6 receptor inhibitors (IL-6Ri) and Janus-kinase inhibitors (JAKi)], in patients with RA stratified by baseline Hb levels using the multicentre observational registry for patients with RA in Japan (ANSWER cohort)...
June 24, 2023: Rheumatology