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Mitral valve replacement

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https://www.readbyqxmd.com/read/29332266/association-between-the-interferon-gamma-874-t-a-polymorphism-and-the-severity-of-valvular-damage-in-patients-with-rheumatic-heart-disease
#1
Erhan Teker, A Basak Akadam-Teker, Oguz Ozturk, Allison Pinar Eronat, Kivanc Yalin, S Ebru Golcuk, Zehra Bugra
Interferon gamma (IFN-γ) is a multifunctional cytokine that plays an important role in modulating almost all phases of the immune response and may be responsible for the increased valvular fibrosis and calcification in the pathogenesis of rheumatic heart disease (RHD). The aim of this study was to investigate the possible relationship between the IFN-γ +874 T/A polymorphism and the severity of valvular damage in the Turkish population. The IFN-γ genotypes were determined in 152 RHD patients and 151 healthy controls by ARMS-PCR...
January 13, 2018: Biochemical Genetics
https://www.readbyqxmd.com/read/29330899/retrograde-transmitral-paravalvular-leak-closure-through-an-antegrade-transseptal-approach-a-novel-technique
#2
Roberto J Cubeddu, Hector J Crespo, Gian M Novaro
Mitral paravalvular leak (PVL) remains a well-known complication after mitral valve replacement. Since the first report over 25 years ago, several catheter-based PVL closure techniques have been described. Most of these comprise of either an antegrade transseptal approach, or a retrograde transaortic or transapical approach. We herein report a novel percutaneous mitral PVL closure technique that was safely and successfully performed after failed attempt using a conventional antegrade approach.
January 13, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29329115/developing-a-mitral-valve-center-of-excellence
#3
Ahmed El-Eshmawi, Javier G Castillo, Gilbert H L Tang, David H Adams
PURPOSE OF REVIEW: Despite the proven superiority of mitral repair over replacement for degenerative mitral disease, mitral valve replacement remains common. Guidelines now recommend referral of patients, particularly those whom are asymptomatic, to valve centers of excellence, although criteria that define such centers remain to be established. The purpose of this review is to define the structure of a mitral center of excellence and to review current clinical outcomes which are possible in such a center...
January 10, 2018: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29325812/transcatheter-mitral-valve-replacement-in-mitral-annulus-calcification-the-art-of-computer-simulation
#4
Júlia Karády, Ioannis Ntalas, Bernard Prendergast, Christopher Blauth, Steven Niederer, Pál Maurovich-Horvat, Ronak Rajani
There is considerable interest in transcatheter prosthetic valve treatment for mitral valve disease in high-risk individuals. Although the presence of mitral annular calcium (MAC) may provide an anchoring zone for such devices, results to date have been modest with reported technical failure rates approaching 30% in specialist centers. This in part relates to the risk of left ventricular outflow tract obstruction and device dislodgment but also to the lack of specific imaging guidelines to plan for such procedures...
January 4, 2018: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29325012/systematic-review-of-the-cost-effectiveness-of-transcatheter-interventions-for-valvular-heart-disease
#5
Gialama Fotini, Prezerakos Panagiotis, Apostolopoulos Vasilis, Nikolaos Maniadakis
Objectives: Transcatheter aortic valve implantation (TAVI) and transcatheter mitral valve repair (TMVR) are increasingly used for managing patients with valvular heart disease to whom surgery presents a high-risk. As these are costly procedures, a systematic review of studies concerned with their economic assessment was undertaken. Methods: The search was performed in PubMed and the Cochrane Library and followed recommended methodological steps. Studies were screened and their data were retrieved and were synthesized using a narrative approach...
January 9, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29321130/exercise-hemodynamic-and-functional-capacity-after-mitral-valve-replacement-in-patients-with-ischemic-mitral-regurgitation-a-comparison-of-mechanical-versus-biological-prostheses
#6
Carlo Fino, Attilio Iacovoni, Philippe Pibarot, John R Pepper, Paolo Ferrero, Maurizio Merlo, Lorenzo Galletti, Massimo Caputo, Paolo Ferrazzi, Constantinos Anagnostopoulos, Diego Cugola, Michele Senni, Diego Bellavia, Julien Magne
BACKGROUND: In patients with ischemic mitral regurgitation requiring mitral valve replacement (MVR), the choice of the prosthesis type is crucial. The exercise hemodynamic and functional capacity performance in patients with contemporary prostheses have never been investigated. To compare exercise hemodynamic and functional capacity between biological (MVRb) and mechanical (MVRm) prostheses. METHODS AND RESULTS: We analyzed 86 consecutive patients with ischemic mitral regurgitation who underwent MVRb (n=41) or MVRm (n=45) and coronary artery bypass grafting...
January 2018: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29317120/preoperative-invasive-hemodynamic-determinants-of-survival-among-patients-undergoing-aortic-or-mitral-valve-surgery
#7
David X Zhuo, Kenneth C Bilchick, Sula Mazimba
OBJECTIVES: To evaluate the association of preoperative invasive hemodynamic parameters with mortality in valvular heart surgery. DESIGN: Retrospective cohort study. SETTING: Single tertiary academic medical center. PARTICIPANTS: A total of 382 patients who underwent preoperative right and/or left heart catheterization before open aortic valve replacement (AVR), open mitral valve repair/replacement (MVR), or combined AVR and MVR, from July 2009 to December 2014...
September 29, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29313150/alfieri-stitch-for-temporary-severe-functional-mitral-regurgitation-after-aortic-valve-replacement
#8
Yoshihisa Morimoto, Takaki Sugimoto
The outcome in functional mitral regurgitation after aortic valve replacement is unclear. A frail 82-year-old woman with severe aortic valve regurgitation and mild to moderate functional mitral valve regurgitation (NYHA functional class III) was referred to our clinic. In consideration of her frail condition, aortic valve replacement without mitral surgery was performed. She had hemodynamic instability and difficulty to wean off cardiopulmonary bypass caused by severe functional mitral valve regurgitation with left ventricular dilatation...
January 8, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29311291/balloon-fracture-of-a-surgical-mitral-bioprosthesis-during-valve-in-valve-transcatheter-mitral-valve-replacement-first-in-human-report
#9
Tsuyoshi Kaneko, Bryan Piccirillo, Harsh Golwala, Agnieszka Trzcinka, Charles Nyman, Douglas Shook, Marc Pelletier, Natalia Berry, Piotr Sobieszczyk, Pinak Shah
No abstract text is available yet for this article.
January 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29304514/antithrombotic-treatment-after-transcatheter-heart-valves-implant
#10
Sabato Sorrentino, Gennaro Giustino, Kamilia Moalem, Ciro Indolfi, Roxana Mehran, George D Dangas
Transcatheter heart valve replacement technology was introduced as alternative to surgery for the growing high-risk profile population. Developed first, aortic valve replacement (TAVR) became a standard of care for patients with severe aortic stenosis at high operative risk, with a potential future use also for low-risk subjects. In the last decade, a multitude of transcatheter mitral valve replacement (TMVR) devices have been developed for the treatment of severe mitral regurgitation, with encouraging results coming from first-in-man and feasibility studies...
January 5, 2018: Seminars in Thrombosis and Hemostasis
https://www.readbyqxmd.com/read/29304513/nonvitamin-k-antagonist-oral-anticoagulants-use-in-patients-with-atrial-fibrillation-and-bioprosthetic-heart-valves-prior-surgical-valve-repair-a-multicenter-clinical-practice-experience
#11
Vincenzo Russo, Emilio Attena, Carmine Mazzone, Francesca Esposito, Valentina Parisi, Ciro Bancone, Anna Rago, Gerardo Nigro, Raffaele Sangiuolo, Antonio D' Onofrio
This is an observational study to investigate the efficacy and safety of nonvitamin K antagonist oral anticoagulants (NOACs) in atrial fibrillation (AF) patients with bioprosthetic valves or prior surgical valve repair in clinical practice. A total of 122 patients (mean age: 74.1 ± 13.2; 54 females) with bioprosthetic heart valve or surgical valve repair and AF treated with NOACs were included in the analysis. The mean CHA2DS2-VASc (Congestive heart failure, Hypertension, Age >75 years, Diabetes mellitus, prior Stroke or transient ischemic attack, Vascular disease) and HAS-BLED (Hypertension, Abnormal renal and liver function, Stroke, Bleeding, Labile INR [international normalized ratio], Elderly, Drugs or alcohol) score values were 3...
January 5, 2018: Seminars in Thrombosis and Hemostasis
https://www.readbyqxmd.com/read/29302936/impact-of-tricuspid-valve-regurgitation-on-early-outcomes-after-transcatheter-aortic-valve-replacement
#12
Mihir Barvalia, Rajiv Tayal, Marc Cohen, Martin Miguel Amor, Lilia Tcharnaia, Chunguang Chen, Mark Russo, Bruce Haik
BACKGROUND: Tricuspid valve regurgitation (TR) is often not taken into consideration in the prognostication of patients undergoing transcatheter aortic valve replacement (TAVR). Accordingly, its impact on such patients remains relatively poorly defined. The study aim was to explore the effect of TR and parameters of right ventricular (RV) function on outcomes in patients undergoing TAVR. METHODS: Baseline demographic and echocardiographic data were collected for 460 consecutive patients undergoing TAVR at the authors' institution between 2012 and 2015...
July 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29301624/transcatheter-mitral-valve-replacement-first-steps-on-a-long-road
#13
EDITORIAL
Josep Rodés-Cabau
No abstract text is available yet for this article.
January 2, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29289363/long-term-outcomes-of-the-mosaic-bioprosthesis
#14
Friedrich-Christian Rieß, Guy Fradet, Andrea Lavoie, Malcolm Legget
BACKGROUND: The Mosaic bioprosthesis is a third-generation stented porcine bioprosthesis. This study was performed to evaluate long-term survival and durability associated with this device. METHODS: A total of 1,029 patients (797 aortic valve replacements, 232 mitral valve replacements) previously enrolled at 6 centers as part of the original regulatory study were included. We evaluated freedom from death, valve-related reoperation, and explant due to structural valve deterioration (SVD), and compared these outcomes by age (<60 and ≥60 years) at the time of implant...
December 27, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29284867/short-term-outcome-of-patients-with-infective-endocarditis-a-single-center-prospective-study
#15
Kianoush Saberi, Mehrdad Salehi, Ali Reza Bakhshandeh, Shahnaz Sharifi, Mehrzad Rahmanian, Roya Sattarzadeh, Anahita Tavoosi
Objectives: To investigate the short-term outcome of patients with infective endocarditis (IE). Patients and Methods: We analyzed data from 42 patients with active endocarditis which underwent different cardiac surgeries. An active endocarditis was considered due to urine analysis and/or blood culture and acute inflammation Gram stains of sample tissue and/or blood culture and acute inflammation Gram stains of sample tissue. Design: Collecting data of 42 patients prospectively...
October 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29284509/should-high-risk-patients-with-concomitant-severe-aortic-stenosis-and-mitral-valve-disease-undergo-double-valve-surgery-in-the-tavr-era
#16
Pey-Jen Yu, Allan Mattia, Hugh A Cassiere, Rick Esposito, Frank Manetta, Nina Kohn, Alan R Hartman
BACKGROUND: Significant mitral regurgitation in patients undergoing transcatheter aortic valve replacement (TAVR) is associated with increased mortality. The aim of this study is to determine if surgical correction of both aortic and mitral valves in high risk patients with concomitant valvular disease would offer patients better outcomes than TAVR alone. METHODS: A retrospective analysis of 43 high-risk patients who underwent concomitant surgical aortic valve replacement and mitral valve surgery from 2008 to 2012 was performed...
December 29, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29284400/medium-term-outcomes-of-78-808-patients-after-heart-valve-surgery-in-a-middle-income-country-a-nationwide-population-based-study
#17
Regina Maria de Aquino Xavier, Vitor Manuel Pereira Azevedo, Paulo Henrique Godoy, Arn Migowski, Antonio Luiz Pinho Ribeiro, Rogério Brant Martins Chaves, Marcelo Goulart Correia, Carolina de Aquino Xavier, Lucas de Aquino Hashimoto, Clara Weksler, Nelson Albuquerque Souza E Silva
BACKGROUND: Heart valve surgery outcomes are unknown in middle-income countries and thus cannot be used in health system decision making processes. This study estimated in-hospital mortality and medium and long-term survival. METHODS: This was a retrospective study of 78,806 patients who underwent heart valve surgery between 2001 and 2007 in Brazil. Two national databases were used, the Hospital Information System and the Mortality Information System. Kaplan-Meier survival analysis and log-rank tests were performed...
December 28, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29281609/improving-the-safety-and-efficacy-of-robotically-assisted-mitral-valve-surgery
#18
REVIEW
Stephanie Mick
To improve outcomes with robotically assisted mitral valve surgery, Cleveland Clinic conducted a study evaluating outcomes in 1,000 consecutive cases. Primary areas of interest were to determine whether increased surgical experience with robotic techniques improved outcomes and to identify opportunities that could improve procedural processes. Results showed that these surgeries were effective and safe in terms of improvements in procedure time, transfusion rates, stroke risk, number of mitral valve replacements, and number of conversions to sternotomy...
December 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29276917/-the-integrated-approach-to-improving-efficiency-and-safety-of-anticoagulation-therapy-in-patients-with-prosthetic-mitral-valve
#19
E V Gorbunova, R R Salakhov, Y N Odarenko, S E Mamchur
AIM: To assess advantages of integrated approach to improvement of efficiency and safety of warfarin therapy after heart valve replacement. MATERIALS AND METHODS: We included in this study 118 patients who had undergone simultaneous mitral valve replacement and maze procedure. Group 1 patients (n=37) underwent just sinus rhythm restoration, group 2 patients (n=54) underwent sinus rhythm restoration and participated in a patient education program, group 3 patients (n=27) underwent sinus rhythm restoration, participated in a patient education program, and were subjected to pharmacogenetic testing for warfarin sensitivity...
November 2017: Kardiologiia
https://www.readbyqxmd.com/read/29258732/using-a-regent-aortic-valve-in-a-small-annulus-mitral-position-is-a-viable-option
#20
Yaron D Barac, Brittany Zwischenberger, Jacob N Schroder, Mani A Daneshmand, Jack Haney, Jeff Gaca, Andrew Wang, Carmelo A Milano, Donald D Glower
BACKGROUND: Outcome of mitral valve replacement in extreme scenarios of small mitral annulus using the Regent mechanical aortic valve is not well documented. METHODS: Records were examined in 31 consecutive patients undergoing mitral valve replacement using the aortic Regent valve due to a small mitral annulus. RESULTS: Mean age was 60±14 years. Mitral stenosis or mitral annulus calcification was present in 30/31(97%) patients. Concurrent procedures were performed in 17/31(55%) patients...
December 16, 2017: Annals of Thoracic Surgery
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