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saliva cortisol

Aniko Krumbholz, Martin Schönfelder, Hande Hofmann, Detlef Thieme
BACKGROUND: The endogenous glucocorticosteroid cortisol (F) and its metabolite cortisone (E) are known to be involved in stress adaption and anti-inflammatory and immune regulatory effects. The ratios of F to E in the matrices serum, hair and saliva are different. The shift of this ratio by the enzyme activity of 11β-hydroxysteroid-dehydrogenase, which inactivates cortisol, was often discussed. The aim of our study was to calculate the contribution of the plasma protein binding (PPB) to this shift...
February 26, 2018: Forensic Science International
Jihui Zhang, Siu Ping Lam, Shirley Xin Li, Yaping Liu, Joey Wing Yan Chan, Michael Ho Ming Chan, Chung Shun Ho, Albert Martin Li, Yun Kwok Wing
INTRODUCTION: There are contradictory findings regarding the associations of parental depression on the hypothalamic-pituitary-adrenal axis activity of their offspring. We aimed to explore the associations of parental depression on the diurnal salivary cortisol profile in their child and adolescent offspring. METHODS: A total of 189 unaffected child and adolescent offspring as determined by structured clinical interview were divided into 3 groups according to their parental history of depression, namely current parental depression (CPD, n = 27), past parental depression (PPD, n = 57), and no parental depression (NPD, n = 105)...
February 27, 2018: Journal of Affective Disorders
Svetlana Tikhonova, Linda Booij, Violet D'Souza, Karla T B Crosara, Walter L Siqueira, Elham Emami
BACKGROUND: This scoping review addressed the question 'what do we know about stress-related changes in saliva and dental caries in general population?' METHODS: The review was conducted using electronic searches via Embase, MEDLINE, PsycINFO, CINAHL and WoS. All published human studies with both observational and experimental designs were included. Two reviewers independently reviewed eligible articles and extracted the data. The studies' quality was assessed using the Effective Public Health Practice Project Quality Assessment Tool...
March 13, 2018: BMC Oral Health
Marloes Langelaan, Jérôme Kisters, Mirjam Oosterwerff-Suiker, Arjen-Kars Boer
Saliva as a diagnostic tool is patient friendly and offers analytical advantages. Hormonal analysis of saliva is not influenced by changes in concentrations of binding globulins as the free concentration of the hormones is measured. Analysis of salivary cortisol is common practice in the diagnostic work-up of hypercortisolism. We investigated the potential role of measuring salivary cortisol when adrenal insufficiency (AI) is suspected, to reduce the numbers of ACTH stimulation tests. Over a period of 6 years, patients undergoing an ACTH stimulation test (tetracosactide, 250 μg) in our hospital were included...
March 12, 2018: Endocrine Connections
Eri Matsubara, Shuichi Kawai
BACKGROUND: Wood is a valuable material for interiors, and the psychophysiological relaxation effects of volatile organic compounds (VOCs) from wood chips and essential oils have been reported. However, few studies have identified the odors in full-scale wooden environment, and also, differences in gender have not been clarified. In this study, we aimed to confirm the effects of VOCs emitted from interior wood walls in both human male and female participants. METHODS: We used Japanese cedar timber and analyzed VOCs in the experimental rooms with and without Japanese cedar timber by gas chromatography-mass spectrometry (GC-MS)...
March 12, 2018: Environmental Health and Preventive Medicine
Nicole C M Korten, Brenda W J H Penninx, Didi Rhebergen, Dorly J H Deeg, Hannie C Comijs
Inconsistent results are found in the involvement of the Hypothalamus-Pituitary-Adrenal (HPA)-axis in cognitive functioning. This study examined the association between various saliva cortisol measures (the 1-h awakening cortisol, evening cortisol, diurnal change, and cortisol suppression) and cognitive functioning (episodic memory, processing speed, interference control, and working memory). Participants were older adults, between 60 and 93 years with (N = 328) and without (N = 119) a depressive disorder from the Netherlands Study of Depression in Older adults...
December 29, 2017: Psychoneuroendocrinology
Marco Mezzullo, Flaminia Fanelli, Guido Di Dalmazi, Alessia Fazzini, Daniela Ibarra-Gasparini, Marianna Mastroroberto, Jenny Guidi, Antonio Maria Morselli-Labate, Renato Pasquali, Uberto Pagotto, Alessandra Gambineri
Hyperandrogenic disorders have been associated with psychological distress, reduced quality of life, anxiety and depression. The hypothalamic-pituitary-adrenal (HPA) axis plays a pivotal role in the adaptive response to stressor events. Salivary cortisol (SalF) and cortisone (SalE) testing have been proven to be useful in the evaluation of HPA-axis activity. This study investigated whether SalF and SalE responses to two putative stressor levels differed between the hyperandrogenic states in late adolescent and young women, thus measuring the HPA-axis adaptive response to acute stress events...
February 24, 2018: Psychoneuroendocrinology
Qingyun Lu, Fada Pan, Lingling Ren, Jing Xiao, Fangbiao Tao
Although numerous studies have described the relationship between HPA axis dysregulation and internalizing symptoms among adolescents, research using hair cortisol concentrations in pre- and young adolescent samples has not been reported. We investigated the association of self-reported internalizing symptoms with cortisol concertration in hair among pre- and young adolescents aged 10-12 years. Forty-six boys and 39 girls supplied a hair sample of at least 3 cm in length for an analysis of this period (3 months) cortisol excretion...
2018: PloS One
John F Hunter, Emily D Hooker, Nicolas Rohleder, Sarah D Pressman
OBJECTIVE: Mobile phones are increasingly becoming a part of the social environment, and when an individual feels excluded during a socially stressful situation, they often retreat to the comfort of their phone to ameliorate the negativity. This study tests whether smartphone presence does, in fact, alter psychological and physiological responses to social stress. METHODS: Participants (N=148, 84% female, mean age=20.4) were subjected to a peer, social-exclusion stressor...
March 8, 2018: Psychosomatic Medicine
John M Violanti, Desta Fekedulegn, Ja Kook Gu, Penelope Allison, Anna Mnatsakanova, Cathy Tinney-Zara, Michael E Andrew
PURPOSE: We hypothesized that effort-reward imbalance (ERI) is associated with an atypical cortisol response. ERI has been associated with higher job stress. Stress triggers cortisol secretion via the hypothalamic-pituitary-adrenal (HPA) axis, and significant deviation from a typical cortisol pattern can indicate HPA axis dysfunction. METHODS: 176 police officers participated from the Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) Study. ERI was the exposure variable...
March 7, 2018: International Archives of Occupational and Environmental Health
Tolga İnce, Hakkı Akman, Dilek Çimrin, Adem Aydın
BACKGROUND: Despite the high prevalence of infantile colic, the pathogenesis remains incompletely understood. Cortisol and melatonin hormones affect gastrointestinal system development in several ways, and interestingly, both cortisol and melatonin's circadian rhythms begin around the 3rd month in which infantile colic symptoms start to decrease. We hypothesized that infantile colic might associate with desynchronization of normal circadian rhythms of these hormones. In this study, we aimed to investigate the role of melatonin and cortisol in the pathogenesis of infantile colic...
March 5, 2018: World Journal of Pediatrics: WJP
Nicole Y L Oei, Steffy W Jansen, Ilya M Veer, P Eline Slagboom, Jeroen van de Grond, Diana van Heemst
INTRODUCTION: Middle-aged offspring from long-lived families are thought to have a slower pace of aging, possibly related to HPA-axis function. Here, we investigated the neural and behavioral effects of social stress in offspring compared to their regular aging partners on emotional distraction during working memory (WM). METHODS: 104 middle-aged participants (53 males) consisting of offspring and their partners underwent the Trier Social Stress Test or a control procedure...
March 2, 2018: Biological Psychology
Eleni Angeli, Terpsichori Korpa, Elizabeth O Johnson, Filia Apostolakou, Ioannis Papassotiriou, George P Chrousos, Panagiota Pervanidou
There is growing evidence for dysregulation of the stress system in individuals with Attention Deficit Hyperactivity Disorder (ADHD). The stress system includes neuroanatomical and functional components that function in concert to maintain homeostasis and its main effectors are the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic/adrenomedullary nervous system (SNS). As stress system activity demonstrates a distinct circadian variation, we aimed to describe simultaneously, diurnal rhythms of both the HPA axis and the SNS in children with ADHD and a comparison group...
February 23, 2018: Psychoneuroendocrinology
Uma Sudhakar, Ramakrishnan Thyagarajan, Bhagyameena Jeyapal, Sushuruthi Jagadeesh, Parvathee Jayakumar
Background: Periodontal disease is not a conventional bacterial infection but is an inflammatory disease initiated by immune response against a group of microorganisms in susceptible hosts. There are many intriguing researches that unfold the secrets of chronic periodontitis. The current researches in chronic periodontitis are directed toward an approach that respects the scientific relationship between the various risk factors, the genetic factors, and the progression of the disease...
September 2017: Journal of Indian Society of Periodontology
Courtney D Lynch, Rajeshwari Sundaram, Germaine M Buck Louis
STUDY QUESTION: Are biomarkers of preconception stress associated with pregnancy loss? SUMMARY ANSWER: Preconception stress, as measured by basal salivary cortisol and alpha-amylase concentrations, is not associated with pregnancy loss. WHAT IS KNOWN ALREADY: Many studies, most of which have been retrospective, have identified an association between stressful life events and perceived stress and miscarriage. STUDY DESIGN, SIZE, DURATION: A prospective pregnancy study with preconception enrollment was conducted between 2005 and 2009...
February 27, 2018: Human Reproduction
Joanna Orysiak, Konrad Witek, Jadwiga Malczewska-Lenczowska, Agnieszka Zembron-Lacny, Andrzej Pokrywka, Dariusz Sitkowski
The aim of this study was to determine the effects of 17 days of training during preparation for the Ice Hockey Under 18 World Championship of the Polish ice hockey national team on the mucosal immune function and monitor upper respiratory tract infection (URTI) incidence before, during and after the competition. Twelve male ice hockey players (age 17.7±0.5 years) were recruited for this study. The first saliva/blood collection took place at the beginning of the training camp (without training at the training camp), the second one was conducted on the 9th day of the training camp immediately after the intensification of training, and the third collection was carried out on the 13th day of training (4 days before leaving for the World Championship) in the tapering phase...
February 27, 2018: Journal of Strength and Conditioning Research
R J Meagher, E Kousvelari
In this review we have highlighted a few innovative microfluidic analytical technologies with mobile phone image processing tools for various bio-chemical tests performed using salivary biomarkers. Saliva-based assays for mobile monitoring with a smartphone sensor provide an excellent analytical technique which can be simple to perform. We describe several examples from the literature, utilizing different modalities of analysis, applied to several different applications of mobile health monitoring: cortisol monitoring, infectious disease testing, and drugs of abuse...
March 2018: Oral Diseases
Hannah E Lapp, Sarah Ahmed, Celia L Moore, Richard G Hunter
Histories of early life stress (ELS) or social discrimination can reach levels of severity characterized as toxic to mental and physical health. Such toxic social stress during development has been linked to altered acute hypothalamic-pituitary-adrenal (HPA) response to social stress in adulthood. However, there are important individual differences in the size and direction of these effects. We explored developmental, genetic, epigenetic, and contextual sources of individual differences in the relationship between ELS, discrimination, and adult responses to acute social stress in a standard laboratory test...
February 21, 2018: Neurotoxicology and Teratology
Jian Liu, Xuemei Qiu, Daoming Wang, Yantao Li, Yang Zong, Yichen Liu, Yue Zhang, Ping Yang, Yong Zuo, Huanming Yang, Jian Wang, Yutao Du, Jin Zi
Objective This study was performed to investigate the effects of age and sex on 10 salivary steroid hormones and analyze the correlations between salivary and plasma hormones. Methods The concentrations of 10 salivary steroid hormones in 1090 Chinese adult volunteers were examined using liquid chromatography-tandem mass spectrometry, and a related investigation was performed on the concentrations of salivary hormones in this population. Results The concentrations of androstenedione (A4), 17α-hydroxyprogesterone (17-OHP), aldosterone (ALD), cortisone (COR), corticosterone (CORT), cortisol (F), progesterone (P), and testosterone were significantly different between men and women (Student's t-test)...
January 1, 2018: Journal of International Medical Research
Francisco J Vaz-Leal, María I Ramos-Fuentes, Laura Rodríguez-Santos, Carlos Chimpén-López, Nieves Fernández-Sánchez, Francisco J Zamora-Rodríguez, Luis Beato-Fernández, Luis Rojo-Moreno, Juan A Guisado-Macías
OBJECTIVE: Clinical research on cortisol response to stress in patients with eating disorders has provided controversial and even contradictory results. As this might be the consequence of the inclusion in the studies of heterogeneous clinical populations, 3 highly selected samples were studied. METHODS: Dexamethasone suppression test was performed on 15 restricting anorexia nervosa patients without history of bulimia nervosa (BN), 17 BN patients with normal weight and no history of anorexia nervosa, and 22 healthy controls...
February 21, 2018: European Eating Disorders Review: the Journal of the Eating Disorders Association
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