Maria Giulia Conti, Sara Terreri, Eva Piano Mortari, Christian Albano, Fabio Natale, Giovanni Boscarino, Giulia Zacco, Patrizia Palomba, Simona Cascioli, Francesco Corrente, Claudia Capponi, Mattia Mirabella, Ane Fernandez Salinas, Alessandra Marciano, Francesca De Luca, Ida Pangallo, Cecilia Quaranta, Claudia Alteri, Cristina Russo, Paola Galoppi, Roberto Brunelli, Carlo Federico Perno, Gianluca Terrin, Rita Carsetti
Importance: Although several studies have provided information on short-term clinical outcomes in children with perinatal exposure to SARS-CoV-2, data on the immune response in the first months of life among newborns exposed to the virus in utero are lacking. Objective: To characterize systemic and mucosal antibody production during the first 2 months of life among infants who were born to mothers infected with SARS-CoV-2. Design, Setting, and Participants: This prospective cohort study enrolled 28 pregnant women who tested positive for SARS-CoV-2 infection and who gave birth at Policlinico Umberto I in Rome, Italy, from November 2020 to May 2021, and their newborns...
November 1, 2021: JAMA Network Open